Provided is a device for treating tinea unguium which allows unrestricted treatment even for patients with basic diseases such as liver diseases, pregnant women and lactating patients and by which interindividual difference in the treatment can be avoided and antifungal agent for external use can be
Provided is a device for treating tinea unguium which allows unrestricted treatment even for patients with basic diseases such as liver diseases, pregnant women and lactating patients and by which interindividual difference in the treatment can be avoided and antifungal agent for external use can be transdermally absorbed from the nail surface to the deep part of the nail economically, safely and efficiently within a short period of time without any side effects. A dome-shaped applicator, which is formed of a flexible material, which has an open part provided with a flange for adhesion and which is formed to have a larger film thickness in the periphery adjacent to the open part than the film thickness in other parts, is hermetically bonded to a surface of a nail. Then, the liquid antifungal agent for external use is fed into the dome-shaped applicator under pressure using an injector and is allowed to be efficiently penetrated into the deep part of the nail using positive pressure.
대표청구항▼
1. A device for treating tinea unguium of nail with a liquid antifungal agent for external use supplied through a needle of an injector, comprising: a dome-shaped applicator formed throughout of an elastic material and consisting essentially of a side wall portion defining an opening at one end ther
1. A device for treating tinea unguium of nail with a liquid antifungal agent for external use supplied through a needle of an injector, comprising: a dome-shaped applicator formed throughout of an elastic material and consisting essentially of a side wall portion defining an opening at one end thereof, an upper portion contiguous to and closing the other end of the side wall portion, and an annular flange formed along a periphery of the opening of the side wall portion and configured to be hermetically adhered to the nail,wherein said side wall portion, together with said upper portion, defines an inside space of the dome-shaped applicator, said inside space being closed when the dome-shaped applicator is attached to the nail with the annular flange being hermetically adhered to the nail,wherein the thickness of the side wall portion is such that the needle is insertible therethrough for injecting the liquid antifungal agent into the inside space but the injected liquid antifungal agent is prevented from exiting therethrough after removal of the needle therefrom,wherein the upper portion hasa thin-walled portion elastically expandable outward when the antifungal agent is fed to the inside space under pressure through the needle inserted through the side wall portion, andwherein the side wall portion has a thickness in the range of 2 to 5 mm and the thin-walled portion has a thickness in the range of 0.02 to 2 mm. 2. The device as recited in claim 1, wherein the elastic material is a rubber material selected from the group consisting of a polybutadiene-based rubber, a butadiene-acrylonitrile-based rubber, a chloroprene-based rubber, an acryl rubber, an acrylonitrile-butadiene rubber, an isoprene rubber, an urethane rubber, an ethylene-propylene rubber, an epichlorohydrin rubber, a chloroprene rubber, a silicone rubber, a styrene-butadiene rubber, a butadiene rubber, a fluorine rubber, a polyisobutyrene rubber and a butyl rubber. 3. The device as recited in claim 1, further comprising an absorbent disposed within the inside space for retaining the liquid antifungal agent supplied to the inside space. 4. The device as recited in claim 1, wherein the thickness of the side wall portion gradually decreases from the periphery of the opening of the side wall portion toward the upper portion. 5. The device as recited in claim 1, wherein the thickness of the side wall portion is such that the needle is insertible therethrough but a pinhole formed in the side wall portion as a result of the insertion of the needle therethrough is spontaneously closed after removal of the needle therefrom, so that when the dome-shaped applicator is attached to the nail with the annular flange being hermetically adhered to the nail and when the needle is inserted through the side wall portion into the closed inside space under pressure and the liquid antifungal agent is injected thereinto, the closed inside space is maintained in a positive pressure after the removal of the needle from the side wall portion.
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이 특허에 인용된 특허 (2)
Rosenberg, Zeil B., Method and apparatus for the transdermal administration of a substance.
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