IPC분류정보
국가/구분 |
United States(US) Patent
등록
|
국제특허분류(IPC7판) |
|
출원번호 |
US-0680351
(2012-11-19)
|
등록번호 |
US-8821412
(2014-09-02)
|
발명자
/ 주소 |
- Gonzalez-Zugasti, Javier
- Boccuti, A. David
- Chickering, III, Donald E.
- Michelman, Mark
- Haghgooie, Ramin
- Davis, Shawn
- James, Scott
- Dadgar, Maisam
- Fisher, Greg
- Miller, Richard L.
- Morse, Christopher J.
- Bernstein, Howard
- Levinson, Douglas A.
|
출원인 / 주소 |
- Seventh Sense Biosystems, Inc.
|
대리인 / 주소 |
Wolf, Greenfield & Sacks, P.C.
|
인용정보 |
피인용 횟수 :
9 인용 특허 :
268 |
초록
▼
The present invention generally relates to receiving bodily fluid through a device opening. In one aspect, the device includes a flow activator arranged to cause fluid to be released from a subject. A deployment actuator may actuate the flow activator in a deployment direction, which may in turn cau
The present invention generally relates to receiving bodily fluid through a device opening. In one aspect, the device includes a flow activator arranged to cause fluid to be released from a subject. A deployment actuator may actuate the flow activator in a deployment direction, which may in turn cause fluid release from a subject. The flow activator may also be moved in a retraction direction by a retraction actuator. In one aspect, the device may include a vacuum source that may help facilitate fluid flow into the opening of the device and/or may help facilitate fluid flow from the opening to a storage chamber. In one aspect, a device actuator may enable fluid communication between the opening and the vacuum source and the flow activator may be actuated after the enablement of fluid communication.
대표청구항
▼
1. A device for receiving fluid from a subject, comprising: a housing including a device actuator and an opening to receive fluid into the housing;a pre-packaged vacuum chamber in the housing, the vacuum chamber having a volume that is at a pressure less than ambient pressure prior to actuation of t
1. A device for receiving fluid from a subject, comprising: a housing including a device actuator and an opening to receive fluid into the housing;a pre-packaged vacuum chamber in the housing, the vacuum chamber having a volume that is at a pressure less than ambient pressure prior to actuation of the device actuator, the vacuum chamber being fluidly coupleable to the opening via a flow path to cause fluid to be drawn into the opening and toward the vacuum chamber along the flow path;a flow control element positioned along the flow path that prevents fluid communication between the vacuum chamber and the opening prior to actuation of the device actuator, the flow control element being configured to enable fluid communication between the opening and the vacuum chamber after actuation of the device actuator and permit fluid flow from the opening toward the vacuum chamber along the flow path;a plurality of microneedles arranged in an array and arranged to be inserted into a subject to cause fluid to be released from the subject;a deployment actuator to move the plurality of microneedles in a deployment direction toward or through the opening, the deployment actuator being configured to move the plurality of microneedles in the deployment direction in response to actuation of the device actuator; anda retraction actuator to move the plurality of microneedles in a retraction direction away from the opening, the retraction actuator being configured to move the plurality of microneedles in the retraction direction in response to actuation of the device actuator. 2. The device of claim 1, wherein the retraction actuator has an initial stored potential energy prior to any deployment movement of the deployment actuator, and wherein release of the stored potential energy causes movement of the plurality of microneedles in the retraction direction. 3. The device of claim 1, wherein a distance between the deployment actuator and the opening is smaller than a distance between the retraction actuator and the opening. 4. The device of claim 1, further comprising a membrane that attaches the plurality of microneedles to the housing and separates the vacuum chamber from the opening. 5. The device of claim 1, wherein the deployment actuator includes a bistable element coupled to the plurality of microneedles and arranged to move from a first stable state to a second stable state in response to actuation of the device actuator, where motion of the bistable element from the first stable state to the second stable state moving between bistable states causes the plurality of microneedles to move in a deployment direction toward or through the opening, and wherein the bistable element is incapable of moving from the second stable state to the first stable state in the absence of an external force on the bistable element. 6. The device of claim 5, wherein the bistable element comprises a snap dome. 7. The device of claim 1, wherein the retraction actuator comprises a leaf spring. 8. The device of claim 1, wherein the flow control element is a seal. 9. The device of claim 8, further comprising a piercing member enclosed by the housing, wherein actuation of the device actuator causes the piercing member to move and pierce the seal. 10. The device of claim 1, further comprising a channel that provides fluid communication between the vacuum chamber and the opening. 11. The device of claim 1, further comprising a membrane positioned between the vacuum chamber and the opening that permits passage of air but prevents passage of liquids into the vacuum chamber. 12. The device of claim 1, wherein the device actuator, the deployment actuator and the flow control element are arranged such that actuation of the device actuator causes the plurality of microneedles to reach the subject after fluid communication between the opening and the vacuum chamber is enabled. 13. The device of claim 1, wherein the deployment actuator is arranged to move the plurality of microneedles in the deployment direction at a higher speed than the retraction actuator is arranged to move the plurality of microneedles in the retraction direction. 14. A device for receiving fluid from a subject, comprising: a housing including a device actuator and an opening to receive fluid into the housing;a pre-packaged vacuum chamber in the housing, the vacuum chamber having a volume at a pressure less than ambient pressure prior to actuation of the device actuator, the vacuum chamber being fluidly coupleable to the opening via a flow path to cause fluid to be drawn into the opening and toward the vacuum chamber along the flow path and the device being configured to enable fluid communication between the opening and the vacuum chamber after actuation of the device actuator;a membrane positioned along the flow path between the vacuum chamber and the opening that permits passage of air but prevents passage of liquids from entering the vacuum chamber;a plurality of microneedles arranged to be inserted into a subject to cause fluid to be released from the subject;a deployment actuator to move the plurality of microneedles in a deployment direction toward or through the opening, the deployment actuator being configured to move the plurality of microneedles in the deployment direction in response to actuation of the device actuator; anda retraction actuator to move the plurality of microneedles in a retraction direction away from the opening, the retraction actuator being configured to move the plurality of microneedles in the retraction direction in response to actuation of the device actuator. 15. The device of claim 14, further comprising a flow control element that prevents fluid communication between the opening and the vacuum chamber, the flow control element being configured to enable fluid communication between the opening and the vacuum chamber after actuation of the device actuator. 16. The device of claim 14, wherein the retraction actuator has an initial stored potential energy prior to any deployment movement of the deployment actuator, and wherein release of the stored potential energy causes movement of the plurality of microneedles in the retraction direction. 17. The device of claim 14, wherein the deployment actuator includes a bistable element coupled to the plurality of microneedles, the bistable element being arranged to move from a first stable state to a second stable state in response to actuation of the device actuator, motion of the bistable element from the first stable state to the second stable state moving the plurality of microneedles in a deployment direction toward or through the opening, and wherein the bistable element is incapable of moving from the second stable state to the first stable state in the absence of an external force on the bistable element. 18. The device of claim 14, wherein the device actuator and the deployment actuator are arranged such that actuation of the device actuator causes the plurality of microneedles to reach the subject after fluid communication between the opening and the vacuum chamber is enabled. 19. A device for receiving fluid from a subject, comprising: a housing including a device actuator and an opening to receive fluid into the housing;a vacuum chamber in the housing at a pressure less than ambient pressure prior to actuation of the device actuator, the device being configured to enable fluid communication between the opening and the vacuum chamber after actuation of the device actuator;a plurality of microneedles arranged in an array and arranged to be inserted into a subject to cause fluid to be released from the subject, wherein the plurality of microneedles are moveable relative to the housing;a deployment actuator including a bistable element arranged to move from a first stable state to a second stable state in response to actuation of the device actuator, wherein the bistable element is coupled to the plurality of microneedles such that motion of the bistable element from the first stable state to the second stable state moves the plurality of microneedles in a deployment direction toward or through the opening, and wherein the bistable element is incapable of moving from the second stable state to the first stable state in the absence of an external force on the bistable element; anda retraction actuator to move the plurality of microneedles in a retraction direction away from the opening, the retraction actuator being configured to move the plurality of microneedles in the retraction direction in response to actuation of the device actuator. 20. The device of claim 19, wherein the deployment actuator, when actuated, moves from a pre-deployment position to a post-deployment position at a peak acceleration of at least 100,000 meters/second2. 21. The device of claim 19, wherein a distance between the deployment actuator and the opening is smaller than a distance between the retraction actuator and the opening. 22. The device of claim 19, wherein the bistable element comprises a snap dome. 23. The device of claim 19, further comprising a channel that provides fluid communication between the vacuum chamber and the opening. 24. The device of claim 19, further comprising a membrane positioned between the vacuum chamber and the opening that permits passage of air but prevents passage of liquids into the vacuum chamber. 25. The device of claim 19, wherein the deployment actuator is arranged to move the plurality of microneedles in the deployment direction at a higher speed than the retraction actuator is arranged to move the plurality of microneedles in the retraction direction. 26. The device of claim 19, further comprising a flow control element that prevents fluid communication between the opening and the vacuum chamber, the flow control element being configured to enable fluid communication between the opening and the vacuum chamber after actuation of the device actuator. 27. The device of claim 26, wherein the device actuator, the deployment actuator and the flow control element are arranged such that actuation of the device actuator causes the plurality of microneedles to reach the subject after fluid communication between the opening and the vacuum chamber is enabled. 28. The device of claim 1, further comprising a storage chamber that is separate and distinct from the vacuum chamber. 29. The device of claim 1, further comprising a release element that contacts the deployment actuator to deploy the plurality of microneedles in response to actuation of the device actuator and releases potential energy stored in the retraction actuator in response to actuation of the device actuator. 30. The device of claim 1, wherein the vacuum chamber is at a pressure that is less than 50 mmHg below atmospheric pressure prior to actuation of the device actuator. 31. The device of claim 14, wherein the vacuum chamber is at a pressure that is less than 50 mmHg below atmospheric pressure prior to actuation of the device actuator. 32. The device of claim 14, further comprising a release element that contacts the deployment actuator to deploy the plurality of microneedles in response to actuation of the device actuator and releases potential energy stored in the retraction actuator in response to actuation of the device actuator.
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