Methods for inhibiting microbial infections associated with sanitary products and for enhancing sanitary product degradation
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A01N-025/34
A01N-063/00
C12N-001/20
출원번호
US-0401701
(2006-04-10)
등록번호
US-8821854
(2014-09-02)
발명자
/ 주소
Farmer, Sean
Lefkowitz, Andrew R.
출원인 / 주소
Ganeden Biotech, Inc.
대리인 / 주소
Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
인용정보
피인용 횟수 :
6인용 특허 :
49
초록▼
The present invention describes compositions and methods for inhibiting microbial infections associated with the use of sanitary products, such as diapers, bandages, sanitary napkins, tampons, and the like. The present invention comprises providing for use a sanitary product containing an effective
The present invention describes compositions and methods for inhibiting microbial infections associated with the use of sanitary products, such as diapers, bandages, sanitary napkins, tampons, and the like. The present invention comprises providing for use a sanitary product containing an effective amount of a viable, non-pathogenic, lactic acid-producing bacteria, such as Bacillus coagulans, or an extracellular product thereof, useful for inhibiting growth of parasites and pathogens on the epithelial tissue in contact with the sanitary product during use of the product. The present invention also provides for enhancing biodegradation of sanitary products after use and disposal. Also described herein are methods using the product and systems containing the compositions.
대표청구항▼
1. A method of inhibiting or preventing a skin infection in a subject suffering from said skin infection or at risk thereof, comprising the step of applying to the skin of the subject an absorbent product comprising a fabric and viable non-pathogenic Bacillus coagulans bacteria, wherein said fabric
1. A method of inhibiting or preventing a skin infection in a subject suffering from said skin infection or at risk thereof, comprising the step of applying to the skin of the subject an absorbent product comprising a fabric and viable non-pathogenic Bacillus coagulans bacteria, wherein said fabric is woven or non-woven, and wherein said bacteria are present on an external surface of said absorbent product, thereby inhibiting or preventing said skin infection. 2. The method of claim 1, wherein said absorbent product is a diaper, towelette, sanitary napkin, tampon, panty protector, incontinence guard, bed sheet, bed protector, clothing, wound or sore dressing, dermal patch, adhesive tape, saliva absorbent product, wash cloth, or bath towel. 3. The method of claim 1, wherein said bacteria are present in the form of spores. 4. The method of claim 1, wherein said bacteria are present in the form of a dried cell mass. 5. The method of claim 1, wherein said bacteria are incorporated into the absorbent product in a liquid, paste, powder, granule, or pellet formulation. 6. The method of claim 1, wherein said absorbent product contains 102 to 1014 of viable bacteria or spores per cubic meter of absorbent product. 7. The method of claim 1, wherein said absorbent product contains 106 to 109 of viable bacteria or spores per cubic meter of absorbent product. 8. The method of claim 1, wherein said Bacillus coagulans is Bacillus coagulans Hammer. 9. The method of claim 1, wherein said absorbent product further comprises a degradation-enhancing, non-pathogenic bacteria that is not Bacillus coagulans selected from the group consisting of a member of the Bacillus genus, the Lactobacillus genus, the Sporolactobacillus genus, the Bifidobacterium genus, and the Pseudomonas genus. 10. The method of claim 1, wherein said absorbent product further comprises an extracellular product of Bacillus coagulans bacteria. 11. The method of claim 1, wherein said absorbent product is disposable. 12. The method of claim 1, wherein said absorbent product comprises a liquid non-permeable back sheet adjacent to an absorbent matrix. 13. The method of claim 1, wherein said absorbent product comprises fibers, non-woven fabric, pellets or aggregates of absorbent material. 14. The method of claim 1, wherein said absorbent product comprises fibers selected from the group consisting of cellulose, cotton, silk, wool, polyester, polyolefin, polyamide, polyvinyl alcohol, polyurethane, polyurea, and polyacrylonitrile. 15. The method of claim 1, wherein said absorbent product comprises a porous material comprising non-woven fabric. 16. The method of claim 1, wherein said absorbent product further comprises an antimicrobial agent, an antiviral agent, or an antifungal agent. 17. The method of claim 1, wherein said absorbent product further comprises a fructooligosaccharide (FOS). 18. The method of claim 1, wherein said skin infection is caused by a Staphylococcus species or a Streptococcus species. 19. The method of claim 1, wherein said skin infection is a dermal or epithelial infection. 20. The method of claim 1, wherein said fabric comprises felt and batting, fiber balls of cotton, rayon, cellulose or synthetic fibers. 21. The method of claim 1, wherein said absorbent product further comprises foam. 22. A method of inhibiting or preventing a skin infection in a subject suffering from said skin infection or at risk thereof, comprising the step of applying to the skin of the subject an absorbent product comprising a fabric and an extracellular supernatant of non-pathogenic Bacillus coagulans bacterial cells, said supernatant in liquid or powder form, wherein said fabric is woven or non-woven, and wherein said supernatant is present on an external surface of said absorbent product, thereby inhibiting or preventing said skin infection.
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