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Kafe 바로가기국가/구분 | United States(US) Patent 등록 |
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국제특허분류(IPC7판) |
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출원번호 | US-0721789 (2010-03-11) |
등록번호 | US-8834564 (2014-09-16) |
발명자 / 주소 |
|
출원인 / 주소 |
|
인용정보 | 피인용 횟수 : 59 인용 특허 : 352 |
A prosthesis is provided for implantation at a native semilunar valve of a native valve complex, the native valve complex having three semilunar sinuses and three native commissures. The prosthesis includes a valve prosthesis support, which comprises a support structure comprising exactly three enga
A prosthesis is provided for implantation at a native semilunar valve of a native valve complex, the native valve complex having three semilunar sinuses and three native commissures. The prosthesis includes a valve prosthesis support, which comprises a support structure comprising exactly three engagement arms that meet one another at three respective junctures. The engagement arms are shaped so as define three peak complexes at the three respective junctures, and three trough complexes, each of which is between two of the peak complexes. Upon implantation of the prosthesis, each of the engagement arms is at least partially disposed within a respective one of the semilunar sinuses, such that each of the peak complexes is disposed distal to and in rotational alignment with a respective one of the native commissures, and each of the trough complexes is disposed at least partially within the respective one of the semilunar sinuses.
1. A valve prosthesis support structure, comprising: a collapsible outer support structure having exactly three distal outer strut supports and exactly three proximal engagement arms, each engagement arm linking two distal outer strut supports, and each engagement arm having an upwardly concave shap
1. A valve prosthesis support structure, comprising: a collapsible outer support structure having exactly three distal outer strut supports and exactly three proximal engagement arms, each engagement arm linking two distal outer strut supports, and each engagement arm having an upwardly concave shape so as to define respective peaks at junctures with the distal outer strut supports and respective troughs between each of respective peaks, wherein the engagement arms diverge radially outward from a longitudinal axis of the valve prosthesis support structure as the engagement arms extend in a proximal direction; anda collapsible inner support structure having exactly three distal inner strut supports extending from a proximal skirt, wherein the proximal skirt includes a flared distal portion, a narrowed throat portion, and a bulging proximal portion;wherein each engagement arm and the proximal skirt define a space configured to receive a native valve leaflet radially between the respective engagement arm and the proximal skirt, wherein each engagement arm forms a radial outer boundary of the space, andwherein the outer support structure is coupled to the inner support structure at respective outer and inner strut supports. 2. The valve prosthesis support structure of claim 1, wherein ends of each engagement arm are at a distance of about 0.5 mm to about 8 mm from ends of the other respective engagement arms. 3. The valve prosthesis support structure of claim 1, wherein the trough of each engagement arm is at a distance of about 1 mm to about 14 mm from the proximal skirt of the inner support structure. 4. The valve prosthesis support structure of claim 1, wherein the inner diameter at the level of the inner support struts of the inner support structure has a diameter of at least about 23 mm, and the trough of each engagement arm is at a distance of about 1 mm to about 14 mm from the proximal skirt of the inner support structure. 5. The valve prosthesis support structure of claim 1, wherein the engagement arms are configured such that the troughs of the engagement arms engage surfaces of semilunar sinuses of a native valve complex. 6. The valve prosthesis support structure of claim 1, wherein the engagement arms axially overlap portions of the flared distal portion and the narrowed throat portion of the proximal skirt. 7. The valve prosthesis support of claim 1, wherein the bulging proximal portion defines a proximal edge of the valve prosthesis. 8. The valve prosthesis support of claim 1, wherein a distal edge of the flared distal portion of the proximal skirt is proximal to a distal edge of the valve prosthesis. 9. The valve prosthesis support of claim 8, wherein the distal edge of the flared distal portion of the proximal skirt is substantially and circumferentially aligned with the junctures. 10. The valve prosthesis support of claim 1, wherein the distal outer strut supports and the distal inner strut supports diverge radially outward from the longitudinal axis as the distal outer strut supports and the distal inner strut supports extend in a distal direction. 11. The valve prosthesis of claim 1, wherein the space defined by each engagement arm and the proximal skirt is sized and configured such that each engagement arm embraces a respective native valve leaflet without folding over the respective native valve leaflet. 12. The valve prosthesis of claim 1, wherein substantially entire portions of the engagement arms diverge radially outward. 13. A valve prosthesis, comprising: a distal fixation member having exactly three distal outer strut supports and exactly three proximal engagement arms, each engagement arm linking two distal outer strut supports, and each engagement arm having an upwardly concave shape so as to define respective peaks at junctures with the distal outer strut supports and respective troughs between each of respective peaks, wherein the engagement arms diverge radially outward from a longitudinal axis of the valve prosthesis support structure as the engagement arms extend in a proximal direction;a proximal fixation member having exactly three distal inner strut supports extending from a proximal skirt, wherein the proximal skirt includes a flared distal portion, a narrowed throat portion, and a bulging proximal portion, wherein the distal fixation member is coupled to the proximal fixation member at respective outer and inner strut supports; anda valve sutured to the proximal fixation memberwherein each engagement arm and the proximal skirt define a space configured to receive a native valve leaflet radially between the respective engagement arm and the proximal skirt, wherein each engagement arm forms a radial outer boundary of the space. 14. The valve prosthesis of claim 13, wherein ends of each engagement arm are at a distance of about 0.5 mm to about 8 mm from ends of the other respective engagement arms. 15. The valve prosthesis support structure of claim 13, wherein the trough of each engagement arm is at a distance of about 1 mm to about 14 mm from the proximal skirt of the proximal fixation member. 16. The valve prosthesis support structure of claim 13, wherein the inner diameter at the level of the inner support struts of the proximal fixation member has a diameter of at least about 23 mm, and the trough of each engagement arm is at a distance of about 1 mm to about 14 mm from the proximal skirt of the proximal fixation member at a distance of about 1 mm to about 10 mm from the proximal skirt of the proximal fixation member. 17. The valve prosthesis of claim 13, wherein the engagement arms are configured such that the troughs of the engagement arms engage surfaces of semilunar sinuses of a native valve complex. 18. The valve prosthesis of claim 13, wherein the engagement arms axially overlap portions of the flared distal portion and the narrowed throat portion of the proximal skirt. 19. The valve prosthesis of claim 13, wherein the bulging proximal portion defines a proximal edge of the valve prosthesis. 20. The valve prosthesis of claim 13, wherein a distal edge of the flared distal portion of the proximal skirt is proximal to a distal edge of the valve prosthesis. 21. The valve prosthesis of claim 20, wherein the distal edge of the flared distal portion of the proximal skirt is substantially and circumferentially aligned with the junctures. 22. The valve prosthesis of claim 13, wherein the distal outer strut supports and the distal inner strut supports diverge radially outward from the longitudinal axis as the distal outer strut supports and the distal inner strut supports extend in a distal direction. 23. The valve prosthesis of claim 13, wherein the space defined by each engagement arm and the proximal skirt is sized and configured such that each engagement arm embraces a respective native valve leaflet without folding over the respective native valve leaflet. 24. The valve prosthesis of claim 13, wherein substantially entire portions of the engagement arms diverge radially outward.
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