Devices and methods for cardiovascular reflex treatments
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61N-001/36
A61N-001/08
출원번호
US-0535817
(2006-09-27)
등록번호
US-8838246
(2014-09-16)
발명자
/ 주소
Kieval, Robert S.
출원인 / 주소
CVRx, Inc.
대리인 / 주소
Patterson Thuente Pedersen P.A.
인용정보
피인용 횟수 :
5인용 특허 :
279
초록▼
Devices, systems and methods are described which control blood pressure, nervous system activity, and neurohormonal activity by activating baroreceptors. By selectively and controllably activating baroreceptors, the present invention reduces excessive blood pressure, sympathetic nervous system activ
Devices, systems and methods are described which control blood pressure, nervous system activity, and neurohormonal activity by activating baroreceptors. By selectively and controllably activating baroreceptors, the present invention reduces excessive blood pressure, sympathetic nervous system activity and neurohormonal activity, thereby minimizing their deleterious effects on a heart, vasculature and other organs and tissues. A baroreceptor activation device is positioned near a low-pressure baroreceptor, preferably in the venous system, heart, or pulmonary vasculature.
대표청구항▼
1. A method for treating a patient with a heart failure condition and having functioning baroreceptors on both a high-pressure side and on a low-pressure side of a vasculature of the patient, comprising: sensing a patient parameter related to the heart failure condition; andusing a control system an
1. A method for treating a patient with a heart failure condition and having functioning baroreceptors on both a high-pressure side and on a low-pressure side of a vasculature of the patient, comprising: sensing a patient parameter related to the heart failure condition; andusing a control system and an implantable baroreceptor activation device to stimulate a baroreceptor on the low-pressure side of the patient's vasculature in response to sensing the patient parameter to treat the heart failure condition at least in part by lowering blood pressure of the patient. 2. A method as in claim 1, wherein the baroreceptor is located in a vein, in a heart, or in a pulmonary artery. 3. A method as in claim 1, wherein the baroreceptor is located in a vein. 4. A method as in claim 3, wherein the vein is selected from the group consisting of the inferior vena cava, the superior vena cava, the portal vein, the jugular vein, the subclavian vein, the iliac vein, and the femoral vein. 5. A method as in claim 1, wherein the baroreceptor activation device stimulates the baroreceptor via adjacent vascular tissue. 6. A method as in claim 1, wherein the baroreceptor activation device provides electrical activation, mechanical activation, thermal activation, or chemical activation. 7. A method as in claim 1, wherein the baroreceptor activation device is configured to provide continuous stimulation, pulsed stimulation, or periodic stimulation. 8. A method as in claim 1, wherein the baroreceptor activation device is controllable by the patient. 9. A method as in claim 1, wherein the baroreceptor is electrically stimulated by the baroreceptor activation device comprising an electrode proximate the baroreceptor. 10. A method as in claim 9, wherein the baroreceptor is located in a pulmonary artery. 11. A method, comprising: providing a control system to a user;providing an implantable baroreflex activation device to the user, the implantable baroreflex activation device coupled to the control system;providing instructions recorded on a tangible medium to the user, the instructions for treating a patient with a heart failure condition and having functioning baroreceptors on both a high-pressure side and on a low-pressure side of a vasculature of the patient, the instructions comprising: sensing a patient parameter related to the heart failure condition; andusing the control system and the implantable baroreceptor activation device to stimulate a baroreceptor on the low-pressure side of the patient's vasculature in response to sensing the patient parameter to treat the heart failure condition at least in part by lowering blood pressure of the patient.
연구과제 타임라인
LOADING...
LOADING...
LOADING...
LOADING...
LOADING...
이 특허에 인용된 특허 (279)
Funke Hermann D. (Bonn DEX), Acoustic body bus medical device communication system.
Berne Robert M. (Charlottesville VA) Belardinelli Luiz (Charlottesville VA) Rubio Rafael (Charlottesville VA), Adenosine antagonists in the treatment and diagnosis of A-V node conduction disturbances.
Boveja Birinder Bob, Apparatus and method for adjunct (add-on) therapy of partial complex epilepsy, generalized epilepsy and involuntary movement disorders utilizing an external stimulator.
Boveja, Birinder R., Apparatus and method for adjunct (add-on) treatment of coma and traumatic brain injury with neuromodulation using an external stimulator.
Schroeppel Edward A. (Miramar FL), Apparatus and method for adjusting heart/pacer relative to changes in venous diameter during exercise to obtain a requir.
Boveja, Birinder R., Apparatus and method for electrical stimulation adjunct (add-on) therapy of atrial fibrillation, inappropriate sinus tachycardia, and refractory hypertension with an external stimulator.
Spreigl William T. ; Hess Douglas N ; Heynen Henri G.,NLX ; Struble Chester I.,NLX ; von Venrooij Paulus C.,NLX, Apparatus and method for fixing electrodes in a blood vessel.
King Gary W., Apparatus and method for treating peripheral vascular disease and organ ischemia by electrical stimulation with closed loop feedback control.
Ding, Jiang; Kramer, Andrew P.; Spinelli, Julio C., Apparatus and method for ventricular pacing triggered by detection of early ventricular excitation.
Arai Makoto R. (Chicago IL) Gordon David (Chicago IL) McAlpine Laura E. (Chicago IL), Apparatus for monitoring cardiovascular regulation using heart rate power spectral analysis.
Kapp John P. (455 Bunkers Cove Rd. Panama City FL 32401) Robertson James T. (628 W. Trezevant Memphis TN 38112) Tucker Elton M. (8 Oxbow Rd. Medfield MA 02052), Arterial pressure control system.
Adkins Robert A. ; O'Donovan Cormac A. ; Terry ; Jr. Reese S., Automatic activation of a neurostimulator device using a detection algorithm based on cardiac activity.
Bozeman ; Jr. Richard J. (Dickinson TX) Akkerman James W. (Houston TX) Aber Gregory S. (Houston TX) Damm George Arthur Van (Houston TX) Bacak James W. (Houston TX) Svejkovsky Paul A. (Webster TX) Ben, Axial pump.
Stadler Robert W. ; Nelson Shannon, Axis shift analysis of electrocardiogram signal parameters especially applicable for multivector analysis by implantable medical devices, and use of same.
Kieval Robert S. ; Bettett Tom D. ; Fitts Stephanie Michele, Baroreflex modulation with carotid sinus nerve stimulation for the treatment of heart failure.
Dahl Roger W. (Andover MN) Swanson David K. (Roseville MN) Hahn Stephen J. (Roseville MN) Lang Douglas J. (Arden Hills MN) Heil John E. (St. Paul MN), Body implantable defibrillation system.
Heil ; Jr. Ronald W. (Roseville MN) Owens Robert C. (Forest Lake MN) Pederson Brian D. (St. Paul MN), Cardiac electrode with drug delivery capabilities.
Ding, Jiang; Spinelli, Julio C.; Kramer, Andrew P., Cardiac rhythm management system selecting between multiple same-chamber electrodes for delivering cardiac therapy.
Baumann, Lawrence S.; Kadhiresan, Veerichetty A., Cardiac rhythm management system with respiration synchronous optimization of cardiac performance using atrial cycle length.
Fogarty Thomas J. (770 Welch Rd. Palo Alto CA 94304) Kinney Thomas B. (San Diego CA) Finn ; III James C. (Menlo Park CA), Catheter with corkscrew-like balloon.
Wolff Rodney G. (468 W. Eagle Lake Dr. Maple Grove MN 55369) Dance Creg W. (812 Benton St. Anoka MN 55303) Letac Brice (134 rue du Renard 76.000 Roven FRX) Cribier Alain (76150 Maromme Maromme FRX), Compressive stent and delivery system.
Claracq Michel (17 ; rue de Vittel 31300 Toulouse FRX), Device for partly occluding a vessel in particular the inferior vena cava and inherent component of this device.
Zacouto Fred (16 rue de la Convention 75 015 Paris FRX), Device for protection against blood-related disorders, notably thromboses, embolisms, vascular spasms, hemorrhages, hemo.
Kieval, Robert S.; Persson, Bruce J.; Serdar, David J.; Keith, Peter T.; Rossing, Martin A., Devices and methods for cardiovascular reflex control via coupled electrodes.
Kieval, Robert S.; Persson, Bruce J.; Serdar, David J.; Keith, Peter T.; Rossing, Martin A., Devices and methods for cardiovascular reflex control via coupled electrodes.
Kasprzyk Daniel J. (Sunnyvale CA) Orth Jean C. (San Jose CA) Gaiser John W. (Mountain View CA) Houser Russell A. (Pleasanton CA), Dilatation catheter assembly with heated balloon.
Kieval,Robert S.; Persson,Bruce J.; Serdar,David J.; Keith,Peter T.; Irwin,Eric D., Electrode designs and methods of use for cardiovascular reflex control devices.
Bolea,Stephen L.; Kieval,Robert S.; Persson,Bruce J.; Serdar,David J.; Keith,Peter T.; Irwin,Eric D.; Rossing,Martin A., Electrode structures and methods for their use in cardiovascular reflex control.
Fenner Andreas A. ; Larson Lary R. ; Greeninger Daniel R. ; Thompson David L., Feedthrough assembly for implantable medical devices and methods for providing same.
Nappholz Tibor A. (Englewood CO) Hursta William N. (Littleton CO) Dawson Albert K. (Denver CO) Steinhaus Bruce M. (Parker CO), Implantable ambulatory electrocardiogram monitor.
Halperin Louis E. (St. Paul MN) Lee Brian B. (Golden Valley MN) Roline Glenn M. (Anoka MN) Varrichio Anthony J. (Flanders NJ), Implantable capacitive absolute pressure and temperature monitor system.
Kroll Mark W. (Minnetonka MN) Nelson Randall S. (Pine Springs MN) Adams Theodore P. (Edina MN), Implantable cardioverter defibrillator pulse generator kite-tail electrode system.
Hassler Beth Anne ; Donders Adriannus P. ; Wiklund Craig L. ; Lyons Daniel A., Implantable ceramic enclosure for pacing, neurological, and other medical applications in the human body.
Obel Israel W. P. (Johannesburg ZAX) Bourgeois Ivan (Verviers BEX), Implantable electrical nerve stimulator/pacemaker with ischemia for decreasing cardiac workload.
Schulman Joseph H. (Santa Clarita CA) Strojnik Primoz (Granada Hills CA) Meadows Paul (Altadena CA), Implantable microdevice with self-attaching electrodes.
Scheiner, Avram; Heil, Jr., Ronald W.; Kelley, Peter T.; Tockman, Bruce; Westlund, Randy; Warren, Jay A., Leads for pacing and/or sensing the heart from within the coronary veins.
Di Domenico Edward D. (Anoka MN) Hobot Christopher M. (Tonka Bay MN) Stokes Kenneth B. (Minneapolis MN) Coury Arthur J. (St. Paul MN) Doan Phong D. (Shoreview MN) Sandstrom Richard D. (Scandia MN), Medical electrical lead with polymeric monolithic controlled release device and method of manufacture.
Stroetmann Brigitte (Uttenreuth DEX) Holmstrom Nils (Jarfalla SEX) Kallert Siegfried (Erlangen DEX) Bowald Staffan (Almunge SEX), Method and apparatus for cardiac therapy by stimulation of a physiological representative of the parasympathetic nervous.
Stadler Robert ; Nelson Shannon ; Stylos Lee ; Sheldon Todd J., Method and apparatus for filtering electrocardiogram (ECG) signals to remove bad cycle information and for use of physiologic signals determined from said filtered ECG signals.
Cohen Richard J. (Waban MA) Appel Marvin L. (Cambridge MA) Berger Ronald D. (Brookline MA), Method and apparatus for physiologic system identification.
Verrier Richard L. (Bethesda MD) Nearing Bruce D. (Bethesda MD), Method and apparatus for prediction of sudden cardiac death by simultaneous assessment of autonomic function and cardiac.
Edell David J. (Lexington MA) Wyatt ; Jr. John L. (Sudbury MA) Rizzo ; III Joseph (Boston MA), Method and apparatus for preferential neuron stimulation.
Webster ; Jr. Wilton W. ; Scherlag Benjamin J. ; Scherlag Michael ; Schauerte Patrick, Method and apparatus for transvascular treatment of tachycardia and fibrillation.
Geddes Leslie A. (West Lafayette IN) Elabbady Tarek (Kirkland WA) Schoenlein William E. (Lafayette IN) Waninger Matthew (Frankfort IN) Bourland Joe D. (West Lafayette IN), Method and apparatus using vagal stimulation for control of ventricular rate during atrial fibrillation.
Geddes Leslie A. ; Elabbady Tarek ; Schoenlein William E. ; Waninger Matthew ; Bourland Joe D., Method and apparatus using vagal stimulation for control of ventricular rate during atrial fibrillation.
Hill Michael R. S. ; Jonkman Kenneth R., Method and device for electronically controlling the beating of a heart using venous electrical stimulation of nerve fibers.
Corbucci Giorgio (San Giovanni In Persiceto ITX), Method and device for monitoring and detecting sympatho-vagal activity and for providing therapy in response thereto.
Brabec Scott J. ; Brennen Kenneth R. ; Schindeldecker William J. ; Spear Stanten C. ; Rugland Roger E. ; Johnson Bruce C., Method for tissue stimulation and fabrication of low polarization implantable stimulation electrode.
Gordon David (Chicago IL) Akselrod Solange (Ramat-Ilan MA ILX) Cohen Richard J. (Newton Highlands MA) Tu Jerome C. (Monterey Park CA) Burns Stephen K. (Henniker NH) DeLeon Victoria H. (Arlington MA), Methods and apparatus for monitoring cardiovascular regulation using heart rate power spectral analysis.
Larsen Charles E. (Cumming GA) Trip Roel (Snellville GA) Johnson Cheryl R. (Atlanta GA), Methods for procedures related to the electrophysiology of the heart.
Naritoku Dean K. ; Jensen Robert A. ; Browning Ronald A. ; Clark Kevin B. ; Smith Douglas C. ; Terry ; Jr. Reese S., Methods of treating traumatic brain injury by vagus nerve stimulation.
Russell,Ted W., Methods, apparatus and articles-of-manufacture for noninvasive measurement and monitoring of peripheral blood flow, perfusion, cardiac output biophysic stress and cardiovascular condition.
Klein George J.,CAX ; Warkentin Dwight H. ; Riff Kenneth M. ; Lee Brian B. ; Carney James K. ; Turi Gregg ; Varrichio Anthony J., Minimally invasive implantable device for monitoring physiologic events.
Kroll Mark W. (Minnetonka MN) Adams Theodore P. (Edina MN) Perttu Joseph S. (Chanhassen MN) Supino Charles (Arden Hills MN), Multiplexed defibrillation electrode apparatus.
Keller ; Jr. John W. (Miami FL) Bursack William E. (New Brighton MN) Coombes Alan (Brooklyn Park MN), Mutually noninterfering transcutaneous nerve stimulation and patient monitoring.
Grandjean Pierre A. (Rue Du Mari 7 Bassenge MN BEX) Lee Philip H. J. (6461 Crackleberry Trail Woodbury MN 55125), Nerve electrode with biological substrate.
Bennett Tommy D. (Shoreview MN) Nichols Lucy M. (Maple Grove MN) Roline Glenn M. (Anoka MN) Thompson David L. (Fridley MN), Rate responsive pacemaker and pacing method.
Doten, Gregory P.; Brockway, Brian P.; Brockway, Robert V.; Fundakowski, Richard A., Respiration monitoring system based on sensed physiological parameters.
Kramer,Andrew P.; Kadhiresan,Veerichetty; Ding,Jiang; Baumann,Lawrence; Vanderlinde,Scott, Resynchronization method and apparatus based on intrinsic atrial rate.
Leonardo Cammilli IT; Gino Grassi IT, SINGLE PASS MULTIPLE CHAMBER IMPLANTABLE ELECTRO-CATHETER FOR MULTI-SITE ELECTRICAL THERAPY OF UP TO FOUR CARDIAC CHAMBERS, INDICATED IN THE TREATMENT OF SUCH PATHOLOGIES AS ATRIAL FIBRILLATION AND C.
Dahl Roger W. (Andover MN) Wickham ; deceased Robert W. (late of Harris MN by Duane Quiggle ; administrator) Swanson David K. (Roseville MN) Lipson David (Poway CA), Stent-type defibrillation electrode structures.
Lee Philip (Woodbury MN) Stokes Kenneth (Brooklyn Park MN) Gates James (Maple Grove MN) Johnson Gary (Ramsey MN), Steroid eluting cuff electrode for peripheral nerve stimulation.
Lee Philip (Woodbury MN) Stokes Kenneth (Brooklyn Park MN) Colson Michael (Minneapolis MN), Steroid eluting electrode for peripheral nerve stimulation.
Bennett Tom D. (Shoreview MN) Combs William J. (Eden Prairie MN) Kallok ; Michael J. (New Brighton MN) Lee Brian B. (Golden Valley MN) Mehra Rahul (Stillwater MN) Klein George J. (London CAX), Subcutaneous multi-electrode sensing system, method and pacer.
Tanagho Emil A. (San Rafael CA) Schmidt Richard A. (San Rafael CA) Gleason Curtis A. (Palo Alto CA) Lue Tom F. (Millbrae CA), Surgically implantable peripheral nerve electrode.
Wernicke Joachim F. (League City TX) Terry ; Jr. Reese S. (Houston TX) Zabara Jacob (Philadelphia PA), Treatment of neuropsychiatric disorders by nerve stimulation.
Wernicke Joachim F. (League City TX) Terry ; Jr. Reese S. (Houston TX) Baker ; Jr. Ross G. (Houston TX), Treatment of patients in coma by nerve stimulation.
Bolea, Stephen L.; Kieval, Robert S.; Persson, Bruce J.; Serdar, David J.; Keith, Peter T.; Irwin, Eric D.; Rossing, Martin A., Electrode structures and methods for their use in cardiovascular reflex control.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.