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A refrigeration system includes a first portion having a primary loop and a secondary loop operably coupled by a first chiller, The primary loop circulates a refrigerant through the first chiller to provide cooling to a coolant in the secondary loop. The secondary loop has a supply portion and a ret

A refrigeration system includes a first portion having a primary loop and a secondary loop operably coupled by a first chiller, The primary loop circulates a refrigerant through the first chiller to provide cooling to a coolant in the secondary loop. The secondary loop has a supply portion and a return portion, the supply portion circulates the coolant to one or more temperature-controlled storage devices operating at a first temperature. A second portion has a primary loop and at least one secondary loop operably coupled by the second chiller. The primary loop circulates a refrigerant through the second chiller to provide cooling to coolant in the secondary loop. The secondary loop has a supply portion and a return portion, the supply portion circulates the coolant to one or more temperature-controlled storage devices operating at a second temperature. The return portion of the secondary loop of the first portion and the return portion of the secondary loop of the second portion share a common return header.

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1. A refrigeration system, comprising: a first portion having a primary loop and a secondary loop operably coupled by a first chiller, the primary loop configured to circulate a refrigerant through the first chiller to provide cooling to a coolant in the secondary loop, the secondary loop having a s

1. A refrigeration system, comprising: a first portion having a primary loop and a secondary loop operably coupled by a first chiller, the primary loop configured to circulate a refrigerant through the first chiller to provide cooling to a coolant in the secondary loop, the secondary loop having a supply portion and a return portion, the supply portion configured to circulate the coolant to one or more temperature-controlled storage devices operating at a first temperature; anda second portion having a primary loop and at least one secondary loop operably coupled by at least one second chiller, the primary loop configured to circulate a refrigerant through the second chiller to provide cooling to coolant in the secondary loop, the secondary loop having a supply portion and a return portion, the supply portion configured to circulate the coolant to one or more temperature-controlled storage devices operating at a second temperature;wherein the return portion of the secondary loop of the first portion and the return portion of the secondary loop of the second portion share a common return header,wherein the second chiller pre-cools the coolant in the common return header to the second temperature and delivers the coolant at the second temperature to the supply portion of the secondary loop of the second portion, wherein the first chiller further cools the pre-cooled coolant from the second temperature to the first temperature and delivers the coolant at the first temperature to the supply portion of the secondary loop of the first portion. 2. The refrigeration system of claim 1, wherein the first temperature is less than the second temperature. 3. The refrigeration system of claim 2, wherein the coolant in the return portion of the secondary loop of the first portion pre-cools the coolant in the return portion of the secondary loop of the second portion. 4. The refrigeration system of claim 3, wherein the return portion of the secondary loop of the first portion diverges from the return portion of the secondary loop of the second portion after the second chiller. 5. The refrigeration system of claim 4, wherein the second chiller pre-cools the coolant in the return portion of the secondary loop of the first portion. 6. The refrigeration system of claim 5, wherein the return header further comprises a pump. 7. The refrigeration system of claim 2, wherein the second chiller comprises a plurality of second chillers, each of the second chillers operably coupled to a secondary loop, and each of the secondary loops operably coupled to a group of temperature-controlled display devices. 8. The refrigeration system of claim 7, wherein each of the groups of temperature-controlled display devices are configured to operate at a different temperature. 9. A refrigeration system, comprising: a first portion having a first primary loop and a secondary loop operably coupled by a first chiller, the first primary loop configured to circulate a refrigerant through the first chiller to provide cooling to a coolant in the secondary loop, the secondary loop having a supply portion and a return portion, the supply portion configured to circulate the coolant to one or more temperature-controlled storage devices operating at a first temperature; anda second portion including at least one modular unit containing a second primary loop and a second chiller, the second portion further including at least one secondary loop operably coupled to the second chiller, the second primary loop configured to circulate a refrigerant through the second chiller to provide cooling to coolant in the secondary loop, the secondary loop having a supply portion and a return portion, the supply portion configured to circulate the coolant to one or more temperature-controlled storage devices operating at a second temperature;wherein the return portion of the secondary loop of the first portion and the return portion of the secondary loop of the second portion share a common return header,wherein the second chiller pre-cools the coolant in the common return header to the second temperature and delivers the coolant at the second temperature to the supply portion of the secondary loop of the second portion, wherein the first chiller further cools the pre-cooled coolant from the second temperature to the first temperature and delivers the coolant at the first temperature to the supply portion of the secondary loop of the first portion. 10. The refrigeration system of claim 9, wherein the first temperature is less than the second temperature. 11. The refrigeration system of claim 10, wherein the at least one modular unit comprises a plurality of modular units, each having a second chiller operably coupled to a secondary loop, and each secondary loop configured to provide coolant to a group of temperature controlled storage devices. 12. The refrigeration system of claim 11, wherein each of the secondary loops share a common supply header and the common return header. 13. The refrigeration system of claim 12, wherein the return portion of the secondary loop of the first portion diverges from the return portion of the secondary loops of the second portion after at least one of the second chillers.