An endoprosthesis component and a method for producing an endoprosthesis component is disclosed. The endoprosthesis component comprises a body predefining the shape of the endoprosthesis component. On surface portions with which the endoprosthesis component in the implanted state is in contact with
An endoprosthesis component and a method for producing an endoprosthesis component is disclosed. The endoprosthesis component comprises a body predefining the shape of the endoprosthesis component. On surface portions with which the endoprosthesis component in the implanted state is in contact with human tissue, the body is covered with an outer layer which comprises a nitride, an oxynitride or an oxide based on a refractory metal and which contains silver and/or copper. An intermediate layer is arranged between the outer layer and the body in such a way that parts of the intermediate layer are accessible from the outside. The endoprosthesis component enables generation of a long-term antimicrobial action with the outer layer and, in addition, action on the surrounding tissue from the intermediate layer.
대표청구항▼
1. An endoprosthesis component comprising: a body;an outer layer covering the body on surface portions configured to come into contact with human tissue in an implanted state, wherein the outer layer consists of: a) a nitride based on a refractory metal, an oxynitride based on a refractory metal or
1. An endoprosthesis component comprising: a body;an outer layer covering the body on surface portions configured to come into contact with human tissue in an implanted state, wherein the outer layer consists of: a) a nitride based on a refractory metal, an oxynitride based on a refractory metal or an oxide based on a refractory metal, and b) one or more of silver and copper; andan intermediate layer arranged between the outer layer and the body, wherein parts of the intermediate layer are accessible to the human tissue in the implanted state. 2. The endoprosthesis component of claim 1, wherein the intermediate layer is composed of one or more of silver, copper and gold. 3. The endoprosthesis component of claim 1 or 2, wherein the outer layer includes interruptions, and wherein the interruptions occupy a proportion of at least 20% of a surface area of the endoprosthesis component across which the endoprosthesis component is configured to come into contact with the human tissue. 4. The endoprosthesis component of claim 3, wherein the outer layer is porous. 5. The endoprosthesis component of claim 4, wherein the outer layer has a microstructure or nanostructure with distinct peaks. 6. A method for producing an endoprosthesis component, comprising: providing a body of the endoprosthesis component covered with an intermediate layer on surface portions of the body that are configured to come into contact with human tissue in an implanted state;providing a refractory metal and also one or more of silver and copper in the form of one or more targets;releasing ions of the refractory metal and also ions of the one or more of silver and copper from the one or more targets; andconducting the ions, together with a reactive gas comprising one or more of oxygen and nitrogen, onto the surface portions covered with the intermediate layer so that an outer layer forms the outer layer consisting of: a) a nitride based on the refractory metal, an oxynitride based on the refractory metal or an oxide based on the refractory metal, and b) the one or more of silver and copper, with the intermediate layer being accessible through said outer layer to the human tissue in the implanted state. 7. The method of claim 6, wherein the ions are released from the one or more targets by means of an electric arc. 8. The method of claim 7, wherein the intermediate layer includes one or more of silver, gold and copper. 9. The method of claim 6, wherein the ions are released from the one or more targets by means of a laser. 10. The method of claim 9, wherein the intermediate layer includes one or more of silver, gold and copper. 11. The method of claim 6, wherein the ions are released from the one or more targets by means of an electron beam. 12. The method of claim 11, further comprising releasing fragments with a diameter of more than 20 μm from the one or more targets, andconducting the fragments onto the body. 13. The method of claim 6, wherein, the intermediate layer includes one or more of silver, gold and copper. 14. The method of claim 13, further comprising prior to the step of conducting the ions, covering a surface portion of the body to be coated with a mask made of a temperature-stable material.
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이 특허에 인용된 특허 (6)
Burrell Robert Edward,CAX ; Rosenfeld Aron Marcus,CAX, Actively sterile surfaces.
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