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A surgical system has a jaw assembly including a plurality of fasteners, an anvil and a drive beam for pushing an actuation sled. A drive screw imparts motion to the drive beam. An elongated body is configured to connect with the jaw assembly. A drive link connects a flexible drive shaft to the driv

A surgical system has a jaw assembly including a plurality of fasteners, an anvil and a drive beam for pushing an actuation sled. A drive screw imparts motion to the drive beam. An elongated body is configured to connect with the jaw assembly. A drive link connects a flexible drive shaft to the drive screw, the drive link being disposed off-axis. The jaw assembly and elongated body are separable from each other.

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1. A surgical system, comprising: a handle housing including a rotatable actuation shaft;an elongated body including a flexible portion and a flexible drive shaft in the flexible portion, the elongated body couplable to the handle housing such that the flexible drive shaft couples to the actuation s

1. A surgical system, comprising: a handle housing including a rotatable actuation shaft;an elongated body including a flexible portion and a flexible drive shaft in the flexible portion, the elongated body couplable to the handle housing such that the flexible drive shaft couples to the actuation shaft; anda jaw assembly couplable to the elongated body, the jaw assembly including: first and second jaws, the second jaw defining a cam surface and pivotally movable relative to the first jaw from an open position to a closed position;a drive beam including a cam member positioned to engage the cam surface of the second jaw member, the drive beam longitudinally movable through the first and second jaw members such that the cam member is translated along the cam surface of the second jaw to move the first and second jaws from the open position to the closed position; anda drive screw supported within the first jaw, the drive screw including a threaded portion threadably coupled to the drive beam, the drive screw coupled to the flexible drive shaft configured to transfer rotational motion of the actuation shaft to the drive screw, such that rotation of the drive screw imparts longitudinal movement of the drive beam. 2. The surgical system according to claim 1, wherein the first jaw includes a removable cartridge assembly including a plurality of fasteners. 3. The surgical system according to claim 2, wherein the second jaw includes an anvil having a fastener forming surface thereon. 4. The surgical system according to claim 3, wherein the jaw assembly further includes an actuation sled supported within the cartridge assembly, the actuation sled being movable to urge the plurality of fasteners from the cartridge assembly. 5. The surgical system according to claim 4, wherein the drive beam abuts the actuation sled such that during longitudinal movement of the drive beam the actuation sled is pushed through the cartridge assembly to urge the plurality of fasteners from the cartridge assembly. 6. The surgical system according to claim 1, wherein the flexible portion includes a plurality of interlocking segments. 7. The surgical system according to claim 1, further comprising a drive link interconnecting the flexible drive shaft and the drive screw, wherein the drive screw defines a first longitudinal axis and the flexible drive shaft defines a second longitudinal axis, and wherein the drive link is disposed off-axis in relation to the first and second longitudinal axes. 8. The surgical system according to claim 7, wherein the drive link includes a proximal engagement portion mechanically coupled to the flexible drive shaft and a distal engagement portion mechanically coupled to the drive screw. 9. The surgical system according to claim 8, wherein the proximal engagement portion includes a socket configured and dimensioned to mechanically interface with a ball joint disposed at a distal end of the flexible drive shaft. 10. The surgical system according to claim 8, wherein the distal engagement portion includes a pin configured and dimensioned to mechanically interface with a clevis disposed at a proximal end of the drive screw. 11. The surgical system according to claim 1, further comprising: a surgical buttress releasably secured to a tissue contacting surface of at least one of the first jaw or the second jaw; anda release assembly disposed within at least one of the first jaw or the second jaw. 12. The surgical system according to claim 11, wherein the drive screw is configured to actuate the release assembly to thereby release the surgical buttress from the at least one of the first jaw or the second jaw. 13. The surgical system according to claim 1, wherein the handle housing further includes a control assembly configured to accept at least one user input. 14. The surgical system according to claim 13, wherein the handle housing further includes a first motor and a second motor configured to operate in response to the at least one user input. 15. The surgical system according to claim 14, wherein the handle housing further includes a power source configured to provide electrical energy to the first and second motors. 16. The surgical system according to claim 14, wherein the handle housing further includes a selector gearbox assembly comprising at least one gear element mechanically coupled to the flexible drive shaft, wherein the first motor is configured to selectively move the at least one gear element into engagement with the second motor to actuate the flexible drive shaft. 17. A surgical system, comprising: an elongated body including a flexible portion and a flexible drive shaft in the flexible portion, the flexible drive shaft defining a first longitudinal axis; anda jaw assembly couplable to the elongated body, the jaw assembly including: first and second jaws, the second jaw defining a cam surface and pivotally movable relative to the first jaw from an open position to a closed position;a drive beam including a cam member positioned to engage the cam surface of the second jaw member, the drive beam longitudinally movable through the first and second jaw members such that the cam member is translated along the cam surface of the second jaw to move the first and second jaws from the open position to the closed position;a drive screw supported within the first jaw, the drive screw defining a second longitudinal axis and including a threaded portion threadably coupled to the drive beam; anda drive link interconnecting the flexible drive shaft and the drive screw, wherein the drive link is disposed off-axis in relation to the first and second longitudinal axes, the drive link configured to transfer rotational motion of the flexible drive shaft to the drive screw, such that rotation of the drive screw imparts longitudinal movement of the drive beam. 18. The surgical system according to claim 17, wherein the first jaw includes a removable cartridge assembly having a plurality of fasteners and the second jaw includes an anvil having a fastener forming surface thereon. 19. The surgical system according to claim 18, wherein the jaw assembly further includes an actuation sled supported within the cartridge assembly, the actuation sled being movable to urge the plurality of fasteners from the cartridge assembly. 20. The surgical system according to claim 19, wherein the drive beam abuts the actuation sled such that during longitudinal movement of the drive beam the actuation sled is pushed through the cartridge assembly to urge the plurality of fasteners from the cartridge assembly.