Temperature compensation for pneumatic pumping system
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
G01F-015/02
A61M-001/28
G06F-017/40
G06F-019/00
출원번호
US-0110357
(2011-05-18)
등록번호
US-8868357
(2014-10-21)
발명자
/ 주소
Huitt, Bruce E.
Vincent, Douglas E.
Hecht, Gideon
출원인 / 주소
Baxter International Inc.
대리인 / 주소
K&L Gates LLP
인용정보
피인용 횟수 :
1인용 특허 :
20
초록▼
Temperature compensation is applied to correct for temperature mismatch between a reference chamber and a disposable chamber in a pneumatic pumping system for dialysis fluid for peritoneal dialysis. The mismatch creates an error in the calculation of pumping volume of dialysate fluid. Applying a cor
Temperature compensation is applied to correct for temperature mismatch between a reference chamber and a disposable chamber in a pneumatic pumping system for dialysis fluid for peritoneal dialysis. The mismatch creates an error in the calculation of pumping volume of dialysate fluid. Applying a correction for the temperature mismatch helps to more precisely control the volume of dialysate that is metered to the patient. Also disclosed are ways to keep temperatures constant and to use temperature sensors to accurately measure the temperatures of the chambers. In other aspects, the temperature of the dialysate fluid itself may be measured and used to apply a correction to the volume of fluid that is pumped to the patient.
대표청구항▼
1. A dialysis system comprising: a disposable cassette including a disposable chamber;a reference chamber; anda controller configured to (i) calculate a volume of air delivered to the disposable chamber using the formula Vd=Vr*(Pr2-Pr1)(Pd1-Pd2),wherein Vd is the volume, Vr is a reference volume of
1. A dialysis system comprising: a disposable cassette including a disposable chamber;a reference chamber; anda controller configured to (i) calculate a volume of air delivered to the disposable chamber using the formula Vd=Vr*(Pr2-Pr1)(Pd1-Pd2),wherein Vd is the volume, Vr is a reference volume of the disposable chamber, and (Pr2−Pr1) is a difference between a pressure in the reference chamber before and after equalization, and (Pd1−Pd2) is a difference between a pressure in the disposable chamber before and after equalization, (ii) calculate a corrected volume of air delivered to the disposable chamber by multiplying Vd by a ratio of a temperature in the disposable chamber to a temperature in the reference chamber Td/Tr, and by a ratio of Trcal/Tdcal, wherein Trcal is a previously measured temperature in the reference chamber and Tdcal is a previously measured temperature in the disposable chamber, and(iii) calculate a corrected volume of dialysate pumped by the dialysis system using the corrected volume of air delivered to the disposable chamber. 2. The dialysis system of claim 1, which includes an expected volume of air in the disposable chamber, and wherein the controller is configured to calculate the corrected volume of dialysate pumped by the dialysis system by adding or subtracting the corrected volume of air in the disposable chamber to or from, respectively, the corrected volume of air delivered to the disposable chamber. 3. The dialysis system of claim 1, wherein the pressures after equalization include pressure measurements after the disposable and reference chambers are pneumatically connected. 4. The dialysis system of claim 1, which includes a sensor for sensing the temperature in the disposable chamber, the sensor located (i) within the disposable chamber, or (ii) on a wall of the disposable chamber. 5. The dialysis system of claim 1, which includes two sensors, wherein the temperature of the disposable chamber is sensed by (i) one of the sensors, or (ii) each of the sensors. 6. The dialysis system of claim 1, which includes two sensors, and the temperature of the reference chamber is sensed by (i) one of the sensors, or (ii) each of sensors. 7. A dialysis system having temperature compensation comprising: a pumping mechanism includinga disposable cassette including at least two pumping chambers, anda reference chamber; anda controller configured to (i) input a temperature measurement of one of the pumping chambers, (ii) select an offset temperature that is dependent on the measured temperature, (iii) apply the offset temperature to the measured temperature, and (iv) correct a volume of air pumped by the particular pumping chamber using the formula Vd=Vr*Tdo*Trcal*(Pr2-Pr1)Tr*Tdcal*(Pd1-Pd2),wherein Vd is the corrected volume, Vr is a nominal chamber volume, Tdo is the temperature of the chamber with the offset applied, Tr is the temperature of the reference chamber, Trcal/Tdcal is a correction factor calibrated at 37° C., and (Pr2−Pr1/(Pd1−Pd2) is a ratio of the pressure differences of the reference chamber and the particular pumping chamber before and after equalization. 8. The dialysis system of claim 7, which includes a temperature sensor for measuring the temperature of the particular pumping chamber, the sensor located in an air path in fluid communication with the particular pumping chamber or attached to a wall inside the particular pumping chamber. 9. The method of claim 7, wherein the controller is further configured to select the offset temperature by (a) inputting a thermal time constant for the particular pump chamber, and (b) applying the thermal time constant to compensate for at least one of the temperature of the particular pump chamber and a temperature of the air pumped. 10. A peritoneal dialysis system including temperature compensation, the system comprising: a pumping system includinga disposable chamber, anda reference chamber; anda controller configured to (i) calculate a volume of air delivered to the disposable chamber using the formula Vd=Vr*(Pr2-Pr1)(Pd1-Pd2),wherein Vd is the volume, Vr is a reference volume of the reference chamber, and (Pr2−Pr1) is a difference between a pressure in the reference chamber before and after equalization, and (Pd1−Pd2) is a difference between a pressure in the disposable chamber before and after equalization, (ii) calculate a corrected volume of air delivered to the disposable chamber by multiplying Vd by a ratio of a temperature of a membrane adjacent the disposable chamber to a temperature in the reference chamber, Tm/Tr, and by a ratio of Trcal/Tdcal, wherein Trcal is a previously measured temperature in the reference chamber, and Tdcal is a previously measured temperature in the disposable chamber, and(iii) calculate a corrected volume of dialysate pumped by the dialysis system using the corrected volume of air delivered to the disposable chamber. 11. The peritoneal dialysis system of claim 10, which includes an expected volume of air in the disposable chamber, and wherein the controller is configured to calculate the corrected volume of dialysate pumped by the dialysis system by adding or subtracting the corrected volume of air in the disposable chamber to or from, respectively, the corrected volume of air delivered to the disposable chamber. 12. The peritoneal dialysis system of claim 10, wherein the pressures after equalization include pressure measurements after the disposable and reference chambers are pneumatically connected. 13. The peritoneal dialysis system of claim 10, wherein the controller is further configured to estimate a temperature of air of the disposable chamber and use the estimated temperature to calculate the corrected volume of air delivered to the disposable chamber. 14. The peritoneal dialysis system of claim 10, including a sensor configured to sense a temperature of air delivered to the disposable chamber, and wherein the controller is further configured to sense a temperature of air delivered to the disposable chamber via the sensor and correct the volume of air delivered to the disposable chamber using the sensed temperature. 15. A peritoneal dialysis system comprising: a pumping system includinga pumping mechanism,a disposable chamber, anda reference chamber; anda controller configured to: (i) measure a temperature of air pumped from the disposable chamber,(ii) calculate a volume of air delivered to the disposable chamber using the formula Vd=Vr*(Pr2-Pr1)(Pd1-Pd2),wherein Vd is the volume, Vr is a reference volume of the reference chamber, and (Pr2−Pr1) is a difference between a pressure in the reference chamber before and after equalization, and (Pd1−Pd2) is a difference between a pressure in the disposable chamber before after equalization, (iii) calculate a corrected volume of air delivered to the disposable chamber by multiplying Vd by: (a) a ratio of an offset temperature to a temperature in the reference chamber, Tm/Tr, the offset temperature including the measured temperature of the air corrected by an offset, wherein the offset depends on the measured temperature and the disposable chamber, and(b) a ratio of Trcal /Tdcal,wherein Trcal is a previously measured temperature in the reference chamber, and Tdcal is a previously measured temperature in the disposable chamber, and(iii) calculate a corrected volume of dialysate pumped by the dialysis system using the corrected volume of air delivered to the disposable chamber. 16. The peritoneal dialysis system of claim 15, which includes a memory operably connected to the controller, wherein a table of offset temperatures is stored in the memory. 17. The peritoneal dialysis system of claim 15, wherein the controller is further configured to calculate the offset temperature by (a) inputting a thermal time constant for the disposable chamber, and (b) applying the thermal time constant in a correction factor to compensate for at least one of the temperature in the disposable chamber and a temperature of the air delivered. 18. A dialysis system comprising: a pneumatic distribution manifold including a heater, anda reference volume chamber;a disposable chamber; anda controller configured to (i) control a temperature of the heater by monitoring a temperature of the manifold, (ii) monitor a temperature of air in the disposable chamber, (iii) calculate a corrected volume of air delivered to the disposable chamber using a temperature of air in the reference volume chamber, and (iv) correct a volume of dialysate pumped by the dialysis system using the calculated corrected volume of air delivered to the disposable chamber. 19. The dialysis system of claim 18, wherein the heater is a first heater, and which includes a second heater, wherein at least one of the first and second heaters is configured to include a set point that is above a desired temperature of dialysate fluid to be delivered by the dialysis system. 20. The dialysis system of claim 18, wherein the disposable chamber is a first disposable chamber, and which includes a second disposable chamber, wherein the volume of air delivered is corrected using an average of a temperature in the two disposable chambers. 21. The dialysis system of claim 18, wherein the calculated corrected volume of air delivered to the disposable chamber includes one of (i) a correction factor of a ratio of a temperature of the disposable chamber to a temperature of the reference chamber, and (ii) a correction factor of a ratio of a calibration temperature of the reference chamber to a calibration temperature of the disposable chamber. 22. The dialysis system of claim 18, wherein the pneumatic distribution manifold is contained within a door assembly of the dialysis system. 23. The dialysis system of claim 18, wherein the heater is a first heater, and which includes a second heater and an enclosure including a positive pressure air tank, a negative pressure air tank and the second heater, and wherein the controller is further configured to heat the enclosure and control a temperature of the air tanks with the second heater. 24. The dialysis system of claim 23, wherein the first heater is at least one of a thermocouple and a thermistor mounted to the reference volume chamber. 25. The dialysis system of claim 23, wherein the pneumatic distribution manifold, the enclosure, the air tanks, and the disposable chamber are contained within a door assembly of the dialysis system.
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이 특허에 인용된 특허 (20)
Albrecht Charles W. (Warminster PA) Cornforth Malcolm W. (Edgewater Park NJ), Calibration system for mechanical gas volume corrector.
Bryant Robert J. (Manchester NH) Bouchard Clement D. (Pembroke NH) Kamen Dean (Bedford NH) Lanigan Richard (Concord NH) Miller Bradley D. (Londonderry NH) Spencer Geoffrey P. (Manchester NH) Vincent , Liquid pumping mechanisms for peritoneal dialysis systems employing fluid pressure.
Bryant Robert J. (Manchester NH) Bouchard Clement D. (Pembroke NH) Kamen Dean (Bedford NH) Lanigan Richard (Concord NH) Miller Bradley D. (Londonderry NH) Spencer Geoffrey P. (Manchester NH) Vincent , Liquid pumping mechanisms for peritoneal dialysis systems employing fluid pressure.
Kamen Dean (Bedford NH) Lanigan Richard (Concord NH) Vincent Douglas E. (Manchester NH), Peritoneal dialysis systems and methods employing a liquid distribution and pump cassette with self-contained air isolat.
Bryant Robert J. (Manchester NH) Kamen Dean (Bedford NH) Vincent Douglas E. (Manchester NH), Peritoneal dialysis systems and methods employing pneumatic pressure and temperature-corrected liquid volume measurement.
Kamen Dean (Bedford NH) Spencer Geoffrey P. (Manchester NH) Vincent Douglas E. (Manchester NH), Peritoneal dialysis systems employing a liquid distribution and pumping cassette that emulates gravity flow.
Kramer David E. (Northbrook IL) Muetterties Andrew J. (Mundelein IL) Szempruch Walter T. (Gurnee IL), Solution pumping system including disposable pump cassette.
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