Reciprocating positive-displacement membrane pumps (which may be referred to hereinafter as “pods,” “pump pods,” or “pod pumps”) used to pump fluids, such as a biological fluid (e.g., blood or peritoneal fluid), a therapeutic fluid (e.g., a medication solution), or a surfactant fluid are disclosed.
Reciprocating positive-displacement membrane pumps (which may be referred to hereinafter as “pods,” “pump pods,” or “pod pumps”) used to pump fluids, such as a biological fluid (e.g., blood or peritoneal fluid), a therapeutic fluid (e.g., a medication solution), or a surfactant fluid are disclosed. The speed of a pump stroke can be adjusted by altering a frequency of pressure pulses delivered to the pump membrane during a fill stroke or a delivery stroke of the pump. A pumping algorithm may divide a pump stroke into an initial pumping period and a end-of-stroke pumping period, with the pressure pulse duration being longer during the initial pumping period. This arrangement may allow for a minimum pump flow rate while also providing a pressure ripple that can be used to detect the end of a pump stroke.
대표청구항▼
1. An actuation system for a reciprocating membrane-based pump having a pumping chamber separated from an actuation chamber by a flexible membrane, a delivery stroke resulting from the application of positive pressure in the actuation chamber, and a fill stroke resulting from the application of nega
1. An actuation system for a reciprocating membrane-based pump having a pumping chamber separated from an actuation chamber by a flexible membrane, a delivery stroke resulting from the application of positive pressure in the actuation chamber, and a fill stroke resulting from the application of negative pressure in the actuation chamber, the actuation system comprising: at least one valve fluidly connecting the actuation chamber with a reservoir arranged to supply positive pressure to the actuation chamber and fluidly connecting the actuation chamber with a reservoir arranged to supply negative pressure to the actuation chamber;a controller configured to signal the at least one valve to operate in a plurality of pulses during a delivery stroke or a fill stroke, each pulse comprising an opening period and a closing period of the valve; whereinthe controller is configured to command the at least one valve to pulse with an opening period during an initial phase of a delivery or fill stroke that is longer than an opening period during a later phase of the delivery or fill stroke. 2. The actuation system of claim 1, wherein the opening period during the initial phase is approximately twice the opening period during the later phase. 3. The actuation system of claim 1, wherein a number of pulses during the initial phase is less than a number of pulses during the later phase. 4. The actuation system of claim 1, further comprising an actuation chamber pressure transducer in fluid communication with the actuation chamber, wherein the controller receives pressure data from the actuation chamber pressure transducer and is configured to increase the opening period of the at least one valve to increase the magnitude of the positive or negative pressure in the actuation chamber. 5. The actuation system of claim 4, wherein the controller is configured to increase the closing period of the at least one valve to decrease the magnitude of the positive or negative pressure in the actuation chamber. 6. The actuation system of claim 4, further comprising a reservoir pressure transducer arranged to measure pressure in the positive pressure reservoir or the negative pressure reservoir, wherein the controller receives pressure data from the reservoir pressure transducer, and is configured to compare the actuation chamber pressure and the reservoir pressure at or near the end of a delivery or fill stroke to indicate the presence of a malfunction of the actuation chamber pressure transducer or the reservoir pressure transducer. 7. The actuation system of claim 1, wherein the at least one valve comprises a first valve fluidly connecting the actuation chamber with the reservoir arranged to supply positive pressure to the actuation chamber; and a second valve fluidly connecting the actuation chamber with the reservoir arranged to supply negative pressure to the actuation chamber. 8. The actuation system of claim 1, wherein the at least one valve comprises a three-way valve fluidly connecting the actuation chamber with the reservoir arranged to supply positive pressure to the actuation chamber and fluidly connecting the actuation chamber with the reservoir arranged to supply negative pressure to the actuation chamber. 9. A method of operating a reciprocating membrane-based pump having a pumping chamber separated from an actuation chamber by a flexible membrane, a delivery stroke resulting from the application of positive pressure in the actuation chamber, and a fill stroke resulting from the application of negative pressure in the actuation chamber, the method comprising: pulsing at least one valve connecting the actuation chamber with a first reservoir arranged to supply positive pressure to the actuation chamber and connecting the actuation chamber with a second reservoir arranged to supply negative pressure to the actuation chamber by switching from an opening period in which the valve is opened or partially opened to a closing period in which the valve is closed or open to a lesser degree than during the opening period a plurality of times during a delivery or fill stroke;andoperating the pulsing so that the opening period of the valve is longer in duration in an initial phase of the delivery or fill stroke than in a later phase of the delivery or fill stroke. 10. The method of claim 9, wherein the duration of the opening period of the at least one valve during the initial phase is approximately twice the duration of the opening period of the at least one valve during the later phase. 11. The method of claim 9, wherein a number of pulses during the initial phase is less than a number of pulses during the later phase. 12. The method of claim 9, further comprising measuring the pressure within the actuation chamber and increasing the duration of the opening period of the at least one valve to increase the magnitude of the positive or negative pressure in the actuation chamber. 13. The method of claim 12, further comprising decreasing the duration of the opening period of the at least one valve to decrease the magnitude of the positive or negative pressure in the actuation chamber. 14. The method of claim 12, further comprising measuring the pressure of the positive pressure reservoir or the negative pressure reservoir, comparing the actuation chamber pressure with the reservoir pressure at or near the end of a delivery or fill stroke, and triggering an alarm to indicate the presence of a malfunction of the pressure measurement in the actuation chamber or the reservoir. 15. The method of claim 9, wherein the at least one valve comprises a first valve fluidly connecting the actuation chamber with the first reservoir; and a second valve fluidly connecting the actuation chamber with the second reservoir, and wherein the pulsing step comprises: pulsing the first valve connecting the actuation chamber with the first reservoir by switching from an opening period in which the first valve is opened or partially opened to a closing period in which the first valve is closed or open to a lesser degree than during the opening period a plurality of times during a delivery stroke; andpulsing the second valve connecting the actuation chamber with the second reservoir by switching from an opening period in which the second valve is opened or partially opened to a closing period in which the second valve is closed or open to a lesser degree than during the opening period a plurality of times during a fill stroke. 16. The method of claim 9, wherein the at least one valve comprises a three-way valve fluidly connecting the actuation chamber with the reservoir arranged to supply positive pressure to the actuation chamber and fluidly connecting the actuation chamber with the reservoir arranged to supply negative pressure to the actuation chamber, and wherein the pulsing step comprises: pulsing the three-way valve connecting the actuation chamber with the reservoir arranged to supply positive pressure to the actuation chamber and connecting the actuation chamber with the reservoir arranged to supply negative pressure to the actuation chamber by switching from an opening period in which the valve is opened or partially opened to a second condition in which the valve is closed or open to a lesser degree than during the opening period a plurality of times during a delivery or fill stroke.
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