[특허]Implants with roughened surfaces

Implants with roughened surfaces 원문보기

IPC분류정보
국가/구분	United States(US) Patent 등록
국제특허분류(IPC7판)	B22F-003/24 A61L-027/50 C22C-014/00 B22F-003/11 A61L-027/04
출원번호	US-0470397 (2009-05-21)
등록번호	US-8871142 (2014-10-28)
발명자 / 주소	Smith, Bryan Rybolt, Jeffrey A. Liu, Derek Hengda Martin, Andrew James
출원인 / 주소	DePuy Synthes Products, LLC
인용정보	피인용 횟수 : 0 인용 특허 : 32

초록 ▼

Provided are methods for processing a green body that includes compacted metal powder, comprising impacting the green body with a particulate material for a time and under conditions effective to displace a portion of the metal powder from the green body. The present methods can be used to prepare green bodies that have “roughened” surfaces and that can be used to make orthopedic implants displaying low movement relative to bone when installed in situ, which corresponds to higher stability upon implantation and decreases the time required for biological fixation of the implant. Also provided are implants comprising a metallic matrix, and methods comprising surgically installing an implant prepared from a “surface roughened” green body in accordance with the present invention.

대표청구항 ▼

1. A method for processing a green body comprising mixing at least one metal powder with extractable particles of salt or sugar, thereby forming a powder mixture in which said metal powder and extractable particles assume respective positions;shaping said power mixture into a shaped object;compacting said shaped object to form said green body;exposing said green body to a solvent in which said extractable particles are soluble to remove at least a portion of said extractable particles thereby forming a green body having a porosity of about 50 to 90%; andimpacting said green body that has been exposed to said solvent with a particulate material for a time and under conditions effective to displace a portion of said metal powder from said green body;sintering said green body having a portion of said metal powder displaced therefrom to form an implant having a roughness that corresponds to a Pa value of at least 50, a roughness that corresponds to a Pp value of at least 90, a roughness that corresponds to a Pt value of at least 200, or a roughness that corresponds to a Pq value of at least 60. 2. The method according to claim 1 wherein said powder mixture comprises about 18 wt. % to about 67 wt. % metal powder, the balance of said powder mixture comprising said extractable particles. 3. The method according to claim 1 wherein said extractable particles are soluble in an aqueous solvent, an organic solvent, or both. 4. The method according to claim 3 wherein said green body is immersed in said solvent to remove said extractable particles. 5. The method according to claim 1 wherein said extractable particles are sodium chloride, potassium chloride, sucrose, potassium sorbate, or any combination thereof. 6. The method according to claim 5 wherein said metal powder comprises titanium, a titanium alloy, a cobalt-chromium alloy, molybdenum, tantalum, niobium, zirconium, stainless steel, or any combination thereof. 7. The method according to claim 1 wherein said particulate material is removable by heating. 8. The method according to claim 6 wherein said particulate material comprises ammonium bicarbonate, urea, biuret, melamine, ammonium carbonate, naphthalene, sodium bicarbonate, or any combination thereof. 9. The method according to claim 6 wherein said particulate material is soluble in an aqueous fluid, and said method further comprises immersing said green body in a bath comprising an aqueous fluid. 10. The method according to claim 9 wherein said particulate material comprises a salt. 11. The method according to claim 1 wherein said particulate material comprises particles having an average diameter of about 150 μm an to about 1250 μm. 12. The method according to claim 1 wherein said particulate material impacts said green body with a pressure of about 3 psi to about 25 psi. 13. The method according to claim 1 wherein impacting is effected for no more than about 2 seconds to about 30 seconds. 14. The method according to claim 1 wherein said particulate material is ejected from an orifice that is positioned about 2 inches to about 30 inches from said green body. 15. The method according to claim 1 wherein said metal powder comprises titanium or a titanium alloy; said extractable particles are sodium chloride or potassium chloride; said particulate material comprises a salt; and said green body is exposed to an aqueous solvent to remove said extractable particles. 16. The method according to claim 15, further comprising the step of immersing said green body that has been impacted with the particulate material in a bath comprising an aqueous fluid to remove said particulate material. 17. The method according to claim 1, where the impacting step is carried out using a blasting pressure ranging from 10 to 25 psi. 18. A method for processing a green body comprising mixing at least one metal powder comprising titanium or titanium alloy with extractable particles of sodium chloride or potassium chloride, thereby forming a powder mixture in which said metal powder and extractable particles assume respective positions;shaping said power mixture into a shaped object;compacting said shaped object to form said green body;exposing said green body to an aqueous solvent in which said extractable particles are soluble to remove at least a portion of said extractable particles thereby forming a green body having a porosity of about 50 to 90%; andimpacting said green body that has been exposed to said solvent with a particulate material comprising a salt for a time and under conditions effective to displace a portion of said metal powder from said green body; andsintering said green body having a portion of said metal powder displaced therefrom to form an implant having a roughness that corresponds to a Pa value of at least 50.

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