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Prevention and treatment of pain using antibodies to sphingosine-1-phosphate 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-039/395
  • C07K-016/44
  • A61K-039/00
출원번호 US-0246704 (2011-09-27)
등록번호 US-8871202 (2014-10-28)
발명자 / 주소
  • Sabbadini, Roger A.
출원인 / 주소
  • Lpath, Inc.
대리인 / 주소
    Acuity Law Group, P.C.
인용정보 피인용 횟수 : 1  인용 특허 : 101

초록

The present invention relates to use of anti-S1P agents, for example, humanized monoclonal antibodies, for prevention and/or treatment of pain, including neuropathic pain, hyperalgesia, allodynia, and chemotherapy-induced pain.

대표청구항 ▼

1. A method of reducing, or reducing the development of, neuropathic pain, allodynia or hyperalgesia in a human subject, comprising administering to a human subject having or believed to be at risk of having pain an antibody or fragment thereof that binds and neutralizes sphingosine-1-phosphate (S1P

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