Apparatus is provided including a prosthesis for implantation at a native semilunar valve of a native valve complex of a subject, the native valve complex having semilunar sinuses, the prosthesis including a valve prosthesis support, which includes a support structure including at least two engageme
Apparatus is provided including a prosthesis for implantation at a native semilunar valve of a native valve complex of a subject, the native valve complex having semilunar sinuses, the prosthesis including a valve prosthesis support, which includes a support structure including at least two engagement arms. Upon implantation of the prosthesis, each of the engagement arms is at least partially disposed within a respective one of the semilunar sinuses. A shape of at least one of the engagement arms is generally characterized by a function z″(r)=0, where z is a height of any given point on the at least one engagement arm measured along a longitudinal axis of the prosthesis, and r is a distance from the longitudinal axis to the given point. Other embodiments are also described.
대표청구항▼
1. Apparatus comprising a prosthesis for implantation at a native semilunar valve of a native valve complex of a subject, the native valve complex having semilunar sinuses, the prosthesis comprising: a collapsible and expandable valve prosthesis support comprising a support structure having exactly
1. Apparatus comprising a prosthesis for implantation at a native semilunar valve of a native valve complex of a subject, the native valve complex having semilunar sinuses, the prosthesis comprising: a collapsible and expandable valve prosthesis support comprising a support structure having exactly three engagement arms and a longitudinal axis,wherein, upon implantation of the prosthesis, each of the engagement arms is configured to be at least partially disposed within a respective one of the semilunar sinuses, andwherein each of the engagement arms comprises an upwardly concave portion, wherein the upwardly concave portion is shaped so as to curve outwards from the longitudinal axis in a lateral direction when the valve prosthesis support is in an expanded state. 2. The apparatus according to claim 1, wherein the valve prosthesis support includes a downstream section and an upstream section, wherein the engagement arms include a downstream end and an upstream end, and wherein the engagement arms extend from the downstream section of the valve prosthesis support towards the upstream section of the valve prosthesis support. 3. The apparatus according to claim 1, wherein the native semilunar valve includes a native aortic valve of the subject, wherein the semilunar sinuses include respective aortic sinuses, and wherein, upon implantation of the prosthesis, each of the engagement arms is configured to be disposed at least partially within the respective one of the aortic sinuses. 4. The apparatus according to claim 1, wherein the native semilunar valve includes a native pulmonary valve of the subject, wherein the semilunar sinuses include respective pulmonary sinuses, and wherein, upon implantation of the prosthesis, each of the engagement arms is configured to be at least partially disposed within the respective one of the pulmonary sinuses. 5. The apparatus according to claim 1, wherein each of the engagement arms comprises an extension element that extends from the engagement arm, wherein the extension element is configured to engage a sinus floor of the respective one of the semilunar sinuses upon implantation of the prosthesis. 6. The apparatus according to claim 2, wherein, when the valve prosthesis support is in an expanded state, the radial distance between the engagement arms and the longitudinal axis generally increases moving from the upstream end to the downstream end of the engagement arms. 7. The apparatus according to claim 1, wherein the prosthesis is configured, upon implantation thereof, to embrace, without squeezing, leaflets of the native semilunar valve. 8. The apparatus according to claim 1, wherein the valve prosthesis support is configured such that, upon implantation of the prosthesis, the valve prosthesis support does not fold over leaflets of the native semilunar valve. 9. The apparatus according to claim 1, wherein the support structure is configured to serve as a distal fixation member,wherein the valve prosthesis support comprises a proximal fixation member, andwherein the proximal fixation member and the engagement arms of the distal fixation member are configured to axially sandwich the native valve complex from ventricular and downstream sides thereof, respectively, upon implantation of the prosthesis. 10. The apparatus according to claim 1, wherein each of the engagement arms is configured to engage a respective one of the semilunar sinuses upon implantation of the prosthesis. 11. The apparatus according to claim 10, wherein each of the engagement arms is shaped so as to define at least one extension element that extends from the engagement arm, and wherein each of the engagement arms and its respective at least one extension element are configured such that the engagement arm engages, via the at least one extension element, a sinus floor of the respective one of the semilunar sinuses upon implantation of the prosthesis. 12. The apparatus according to claim 10, wherein the longitudinal length of each of the engagement arms, as measured along a line parallel to a longitudinal axis of the prosthesis, is greater than 6 mm. 13. The apparatus according to claim 1, wherein the prosthesis further comprises a prosthetic valve comprising one or more prosthetic leaflets, wherein at least a portion of each of the prosthetic leaflets is configured to assume a closed position during diastole and an open position during systole, and wherein the at least a portion is not directly coupled to any of the engagement arms. 14. The apparatus according to claim 13, wherein the prosthetic valve is coupled to the support structure such that at least 50% of an axial length of the prosthetic leaflets is distal to native valve leaflets of the native semilunar valve, upon implantation of the prosthesis. 15. The apparatus according to claim 1, wherein the engagement arms are configured to touch respective floors of the respective semilunar sinuses, upon implantation of the prosthesis. 16. The apparatus according to claim 15, wherein the engagement arms are configured to firmly engage the respective semilunar sinuses, upon implantation of the prosthesis. 17. Apparatus comprising a prosthesis for implantation at a native semilunar valve of a native valve complex of a subject, the native valve complex having semilunar sinuses, the prosthesis comprising: a collapsible and expandable valve prosthesis support comprising a support structure comprising at least two engagement arms, wherein the valve prosthesis support includes a downstream section and an upstream section, wherein the engagement arms extend from the downstream section of the valve prosthesis support towards the upstream section of the valve prosthesis support,wherein, upon implantation of the prosthesis, each of the engagement arms is configured to be at least partially disposed within a respective one of the semilunar sinuses, andwherein each of the engagement arms comprises an upwardly concave portion, wherein the upwardly concave portion is shaped so as to curve outwards from the longitudinal axis in a lateral direction when the valve prosthesis support is in an expanded state.
연구과제 타임라인
LOADING...
LOADING...
LOADING...
LOADING...
LOADING...
이 특허에 인용된 특허 (311)
Yock Paul G. (1216 San Mateo Dr. Menlo Park CA 94025), Angioplasty apparatus facilitating rapid exchanges.
Barbut, Denise; Root, Jonathan D.; Pastrone, Giovanni; Maahs, Tracy D.; Tsugita, Ross S., Aortic occluder with associated filter and methods of use during cardiac surgery.
Taheri Syde (268 Dan Troy Williamsville NY 14221) Leonhardt Howard J. (13794 NW. 4th St. ; Bldg. #210 Sunrise FL 33325), Apparatus and method for engrafting a blood vessel.
Lenker Jay A. ; Freislinger Kirsten ; Evans Michael A. ; Watanabe Gwendolyn A. ; Ryan Timothy J. ; Zarins Christopher K. ; Murphy Richard O., Apparatus and methods for placement and repositioning of intraluminal prostheses.
Chuter Timothy A.,SEX ; DeBruyne Michael P. ; Fearnot Neal E. ; Elliott Gregory D., Barb and expandable transluminal graft prosthesis for repair of aneurysm.
Paul F. Chouinard ; Dennis A. Peiffer ; Patrick A. Haverkost, Braided branching stent, method for treating a lumen therewith, and process for manufacture therefor.
White, Bradley R.; Chouinard, Paul F.; Peiffer, Dennis A.; Haverkost, Patrick A., Braided, branched, implantable device and processes for manufacture thereof.
Roberts George T. (Weston MA) Hess Kathleen L. (Lynn MA) Nott Sepideh H. (Canton MA) Chu Michael S. H. (Brookline MA) Chin Yem (Burlington MA), Controlled deployment of a medical device.
Liotta Domingo S. (3 De Febrero 2025 Buenos Aires ARX) Troncoso De Liotta Holga E. (3 De Febrero 2025 Buenos Aires ARX 1428), Diaphragm and method for occlusion of the descending thoracic aorta.
Tchakarov Borislav J. ; DiFoggio Rocco ; Forgang Stanislav W. ; Fanini Otto N. ; Hunziker James C. ; Civarolo Marcelo F., Downhole carbon dioxide gas analyzer.
Julio C. Palmaz ; Eugene A. Sprague ; Cristina Simon ; Denes Marton ; Roger W. Wiseman ; Christopher E. Banas, Endoluminal device exhibiting improved endothelialization and method of manufacture thereof.
Valley, Kirsten L.; Snow, David W.; Corvi, Timothy C.; Donlon, Brian S.; Boyd, Stephen W.; Fan, Sylvia W.; Roth, Alex T.; Peters, William S.; Mueller, Jr., Richard J.; Gifford, III, Hanson S., Endovascular system for arresting the heart.
Suh Soo Won,KRX ; Kim In Young,KRX ; Choo In Wook,KRX ; Do Young Soo,KRX ; Choo Sung Wook,KRX, Flexible self-expandable stent and method for making the same.
Carpentier Alain (Paris FRX) Carpentier Sophie (Paris CA FRX) Nashef Aws S. (Costa Mesa CA), Implantable biological tissue and process for preparation thereof.
Carpentier Alain (Paris FRX) Carpentier Sophie (Paris CA FRX) Nashef Aws S. (Costa Mesa CA), Implantable biological tissue and process for preparation thereof.
Block Peter C. (3510 SW. Sherwood Pl. Portland OR 97201) Anderson W. Earl (230 E. 38th Ave. Eugene OR 97405-4714) Atteridge David G. (18235 SW. Barcelona Way Beaverton OR 97007), Inflatable prosthetic cardiovascular valve for percutaneous transluminal implantation of same.
Garrison Michi E. ; Donlon Brian S. ; Mueller ; Jr. Richard L., Method and apparatus for minimizing the risk of air embolism when performing a procedure in a patient's thoracic cavity.
Liddicoat, John R.; Lambrecht, Gregory H.; Davenport, Todd F.; Cohn, William E.; Woolfson, Steven B.; Taylor, Daniel C., Method and apparatus for performing a procedure on a cardiac valve.
Stenzel, Eric B.; Sahatjian, Ronald A.; Zhong, Sheng-ping; Dao, Kinh-Luan D.; Dayton, Peter L.; Kalashian, Daniel J.; Griffin, Stephen; Chien, Thomas Yung-hui, Method and device for providing full protection to a stent.
Nguyen Than (Huntington Beach CA) Nashef Aws (Huntington Beach CA) Abolfathi Amir H. (Laguna Hills CA) Wieting David W. (Irvine CA) Lee Denis (Irvine CA), Method and device for testing venous valves.
Nguyen Than (Huntington Beach CA) Nashef Aws (Huntington Beach CA) Abolfathi Amir H. (Laguna Hills CA) Wieting David W. (Irvine CA) Lee Denis (Irvine CA), Method for testing venous valves.
Yang, Jibin; Heneveld, Sr., Scott Hyler; Pease, Matthew Lane; Walsh, Brandon G., Methods and apparatuses for deploying minimally-invasive heart valves.
Zadno-Azizi Gholam-Reza ; Luehrs Kirsten F. ; Gittings Darin C. ; Turovskiy Roman ; Cox Brian J. ; Shiu Brian ; Hayes Michael B. ; Coombs Craig J., Methods for the manufacture of radially expansible stents.
Hachtman Steven W. (Chanhassen MN) Johnson Liann M. (Golden Valley MN) Johnson Scott T. (Anoka MN) Laptewicz ; Jr. Joseph E. (Eden Prairie MN) Thompson Paul J. (New Hope MN) Ahmad Amjad (Eagan MN) Sc, Multiple layer stent.
Cribier Alain (Maromme FRX) Letac Brice (Rouen RI FRX) Ariola ; Jr. John P. (East Providence RI), Procedure and catheter instrument for treating patients for aortic stenosis.
Bokros Jack C. ; Ely John L. ; Emken Michael R. ; Haubold Axel D. ; Peters T. Scott ; Stupka Jonathan C. ; Waits C. Thomas, Prosthetic heart valve with improved blood flow.
Quijano R. C. (Laguna Hills CA) Nashef Aws (Huntington Beach CA), Stent devices and support/restrictor assemblies for use in conjunction with prosthetic vascular grafts.
Ross Donald N. (25 Upper Wimpole St. London W.1 GB2) Bodnar Endre (9 West End Ct. ; West End Ave. Pinner ; Middlesex GB2) Hoskin William J. (5 Long Buftlers Harpenden ; Hertfordshire GB2), Stent for a cardiac valve.
An Sung Soon,KRX ; Kim Chel Seng,KRX ; Choi Sung Pil,KRX ; Kim Tae Hyung,KRX ; Song Ho Young,KRX ; Song Sang Woo,KRX, Stent for expanding body's lumen.
McVenes Rick D. (Isanti MN) Stokes Kenneth B. (Brooklyn Park MN) Pohndorf Peter J. (Stillwater MN) Proctor Keith J. (Lino Lakes MN), Steroid eluting stitch-in chronic cardiac lead.
Stevens John H. (Palo Alto CA) Sterman Wesley D. (San Francisco CA) Gifford ; III Hanson S. (Woodside CA) Machold Timothy R. (Moss Beach CA), System for cardiac procedures.
Sabbaghian Mehdy (Baton Rouge LA) Dailey Russell S. (Metairie LA) Dobson Gregory T. (Baton Rouge LA) Tang Hing W. (Perak LA MYX) Schwartzberg Glen J. (Baton Rouge LA), Valve cutter for arterial by-pass surgery.
Andersen, Henning Rud; Hasenkam, John Michael; Knudsen, Lars Lyhne, Valve prosthesis for implantation in the body and a catheter for implanting such valve prosthesis.
Andersen, Henning Rud; Hasenkam, John Michael; Knudsen, Lars Lyhne, Valve prosthesis for implantation in the body and a catheter for implanting such valve prosthesis.
Andersen Henning R. (Dalvangen 37A DK-8270 Hoejbjerg DKX) Hasenkam John M. (Aprilvej 8 DK-8210 Aarhus V DKX) Knudsen Lars L. (RudolfWulffsgade 6,4.mf. DK-8000 Aarhus C DKX), Valve prothesis for implantation in the body and a catheter for implanting such valve prothesis.
Palmaz,Julio C.; Sprague,Eugene A.; Fuss,Cristina; Marton,Denes; Wiseman,Roger W.; Banas,Christopher E.; Boyle,Christopher T.; Bailey,Steven R., Valvular prostheses having metal or pseudometallic construction and methods of manufacture.
Braido, Peter N.; Ashworth, Paul E.; Schraut, Julia A., Collapsible and re-expandable prosthetic heart valve cuff designs and complementary technological applications.
Braido, Peter N.; Ashworth, Paul Edward; Schraut, Julia Ann, Collapsible and re-expandable prosthetic heart valve cuff designs and complementary technological applications.
Braido, Peter N.; Ashworth, Paul Edward; Schraut, Julia Ann, Collapsible and re-expandable prosthetic heart valve cuff designs and complementary technological applications.
Braido, Peter N.; Ashworth, Paul Edward; Schraut, Julia Ann, Collapsible and re-expandable prosthetic heart valve cuff designs and complementary technological applications.
Braido, Peter N.; Ashworth, Paul Edward; Schraut, Julia Ann, Collapsible and re-expandable prosthetic heart valve cuff designs and complementary technological applications.
Braido, Peter N.; Ashworth, Paul Edward; Schraut, Julia Ann, Collapsible and re-expandable prosthetic heart valve cuff designs and complementary technological applications.
Braido, Peter Nicholas; Ashworth, Paul Edward; Schraut, Julia Ann, Collapsible and re-expandable prosthetic heart valve cuff designs and complementary technological applications.
Braido, Peter N.; Alkhatib, Yousef F.; Anderl, Steven Frederick; Daly, Jacob John; Fahim, Mina S.; Smith, Kent J.; Thomas, Ralph J., Paravalvular sealing via extended cuff mechanisms.
Braido, Peter N.; Smith, Kent J.; McCarthy, Andrea L.; Fahim, Mina S., Stationary intra-annular halo designs for paravalvular leak (PVL) reduction—active channel filling cuff designs.
Braido, Peter N.; Smith, Kent J.; McCarthy, Andrea L.; Para, Andrea N.; Khouengboua, Sounthara (Ott); Benson, Thomas M.; Kumar, Saravana B.; Moseman, Bruce; Satam, Gaurav, Subannular sealing for paravalvular leak protection.
Ganesan, Kavitha; Venkatasubramanian, Ramji T.; Forsberg, Andrew T.; Schweich, Jr., Cyril J.; Mortier, Todd J.; Martz, Erik O.; Krone, Douglas J., Systems and methods for heart valve therapy.
Ganesan, Kavitha; Venkatasubramanian, Ramji; Forsberg, Andrew T.; Schweich, Jr., Cyril J.; Mortier, Todd J.; Martz, Erik O.; Krone, Douglas J., Systems and methods for heart valve therapy.
Ganesan, Kavitha; Venkatasubramanian, Ramji; Forsberg, Andrew T.; Schweich, Jr., Cyril J.; Mortier, Todd J.; Martz, Erik O.; Krone, Douglas J., Systems and methods for heart valve therapy.
Morin, Kristen T.; Para, Andrea N.; Braido, Peter N.; Khouengboua, Sounthara; Benson, Thomas M.; Kumar, Saravana B.; Moseman, Bruce; Satam, Gaurav, Transcatheter valve with paravalvular leak sealing ring.
Morin, Kristen T.; Para, Andrea N.; Braido, Peter N.; Khouengboua, Sounthara; Benson, Thomas M.; Kumar, Saravana B.; Moseman, Bruce; Satam, Gaurav, Transcatheter valve with paravalvular leak sealing ring.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.