최소 단어 이상 선택하여야 합니다.
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다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
DataON 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Edison 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Kafe 바로가기국가/구분 | United States(US) Patent 등록 |
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국제특허분류(IPC7판) |
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출원번호 | US-0946175 (2013-07-19) |
등록번호 | US-8880154 (2014-11-04) |
발명자 / 주소 |
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출원인 / 주소 |
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인용정보 | 피인용 횟수 : 4 인용 특허 : 390 |
An intracorporeal marker includes a fibrous unitary marker body having bioabsorbable fibers compressed into a compressed configuration, and bound in the compressed configuration by a polymer binding agent. The intracorporeal marker may be incorporated into an intracorporeal marker delivery device ha
An intracorporeal marker includes a fibrous unitary marker body having bioabsorbable fibers compressed into a compressed configuration, and bound in the compressed configuration by a polymer binding agent. The intracorporeal marker may be incorporated into an intracorporeal marker delivery device having a delivery cannula which has a distal tip, an inner lumen and a discharge opening in communication with the inner lumen. The compression and binding occur prior to insertion of the fibrous unitary marker body into the inner lumen of the delivery cannula. The fibrous unitary marker body is slidably disposed within and pushable through the inner lumen of the elongated delivery cannula proximal to the discharge opening.
1. An intracorporeal marker comprising a fibrous unitary marker body having bioabsorbable fibers compressed into a compressed configuration, and bound in the compressed configuration by a polymer binding agent. 2. The intracorporeal marker of claim 1, wherein a radiopaque marker element is incorpora
1. An intracorporeal marker comprising a fibrous unitary marker body having bioabsorbable fibers compressed into a compressed configuration, and bound in the compressed configuration by a polymer binding agent. 2. The intracorporeal marker of claim 1, wherein a radiopaque marker element is incorporated into the fibrous unitary marker body. 3. The intracorporeal marker of claim 2, wherein the radiopaque marker element is disposed about the fibrous unitary marker body. 4. The intracorporeal marker of claim 1, wherein the bioabsorbable fibers comprise a bioabsorbable material selected from the group consisting of cellulose, polylactic acid, a copolymer of polylactic acid and glycolic acid, and polycaprolactone. 5. The intracorporeal marker of claim 4, wherein the cellulose is oxidized, regenerated cellulose. 6. The intracorporeal marker of claim 1, wherein the bioabsorbable fibers comprise a woven fabric. 7. The intracorporeal marker of claim 1, wherein the bioabsorbable fibers comprise a felt fabric. 8. The intracorporeal marker of claim 1, wherein the polymer binding agent comprises one or more water soluble polymers selected from the group consisting of polyvinyl alcohol, polyethylene glycol, polyvinyl pyrollidone. 9. The intracorporeal marker of claim 1, wherein the fibrous unitary marker body includes at least one bioactive component selected from the group consisting of therapeutic and diagnostic agents incorporated therein. 10. The intracorporeal marker of claim 1, wherein the bioabsorbable fibers comprise a material selected from the group consisting of polylactic acid, a co-polymer of polylactic acid and glycolic acid, polycaprolactone, collagen and mixtures thereof, including mixtures with oxidized cellulose. 11. The intracorporeal marker of claim 1, further comprising a constricting member configured to hold a portion of the fibrous unitary marker body to prevent an expansion of the portion upon contact with a water-based fluid. 12. The intracorporeal marker of claim 11, wherein the constricting member is a radiographically detectable marker element. 13. The intracorporeal marker of claim 1, wherein the fibrous unitary marker body comprises a core of bioabsorbable felt surrounded by a bioabsorbable fabric jacket. 14. The intracorporeal marker of claim 1, wherein a radiopaque marker element is incorporated into the fibrous unitary marker body. 15. An intracorporeal marker delivery device, comprising: a delivery cannula which has a distal tip, an inner lumen and a discharge opening in communication with the inner lumen; anda fibrous unitary marker body comprising bioabsorbable fibers which is compressed into a compressed configuration and bound in the compressed configuration by a binding agent prior to insertion into the inner lumen of the delivery cannula, the fibrous unitary marker body being slidably disposed within and pushable through the inner lumen of the elongated delivery cannula proximal to the discharge opening. 16. The intracorporeal marker delivery device of claim 15, wherein the bioabsorbable fibers expand upon contact with body fluid or other water based fluid. 17. The intracorporeal marker delivery device of claim 15, further comprising a short term ultrasonically detectable marker slidably disposed within the inner lumen of the delivery cannula proximal to the discharge opening. 18. The intracorporeal marker delivery device of claim 15, wherein the discharge opening of the delivery cannula is occluded by a bioabsorbable plug to prevent the premature contact of the fibrous unitary marker body within the inner lumen with body fluids at a tissue site. 19. An intracorporeal marker comprising a fibrous unitary marker body having bioabsorbable fibers compressed into a compressed configuration, and bound in the compressed configuration by a binding agent. 20. The intracorporeal marker of claim 19, wherein the fibrous unitary marker body comprises a core of bioabsorbable felt surrounded by a bioabsorbable fabric jacket.
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