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A sterile connector assembly for mounting on a fluid system includes a first connector and a second connector. The first connector includes a stem defining a fluid passage therethrough, a first housing surrounding the stem and defining a first aperture, and a first valve disposed over the first aper

A sterile connector assembly for mounting on a fluid system includes a first connector and a second connector. The first connector includes a stem defining a fluid passage therethrough, a first housing surrounding the stem and defining a first aperture, and a first valve disposed over the first aperture. The second connector includes a second housing configured to matingly engage the first housing. The second housing defines a second aperture and defines a seal structure. The seal structure is configured to engage the stem. The second connector also includes a second valve disposed over the second aperture. The second valve is configured to engage the first valve when the first housing engages the second housing.

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1. A connector comprising: a stem defining a fluid passage therethrough having a proximal end, a distal end, and a uniform length therebetween, wherein the proximal end of the stem includes an internal chamber with an open end and is configured to matingly engage a complimentary seal structure havin

1. A connector comprising: a stem defining a fluid passage therethrough having a proximal end, a distal end, and a uniform length therebetween, wherein the proximal end of the stem includes an internal chamber with an open end and is configured to matingly engage a complimentary seal structure having a seal located on an outside diameter of a fluid passage on a complimentary connector;a housing surrounding the stem and defining an aperture, wherein the housing is configured to engage a complimentary housing of the complimentary connector; anda valve disposed over the aperture, wherein a majority of an innermost surface area of an external surface of the valve is configured to align with and seal to a majority of an innermost surface area of an external surface of a complimentary valve when the housing engages the complimentary housing, and wherein the stem is configured to move in relation to the housing and open a path for a fluid to flow between a distal end of the connector positioned furthest from the complimentary connector and a distal end of the complimentary connector positioned furthest from the connector by uniformly engaging the valve to fold open the valve and complimentary valve. 2. The connector of claim 1, wherein the stem is configured to move in relation to the housing and through the valve and complimentary valve to engage the complimentary seal structure after the housing engages the complimentary housing. 3. The connector of claim 2, wherein the valve is configured to fold with the complimentary valve in a direction of movement of the stem when the stem moves through the valve and the complimentary valve. 4. The connector of claim 1, wherein the valve comprises a silicone elastomer, an ethylene propylene diene monomer (EPDM), a thermoplastic elastomer (TPE), or a thermoplastic vulcanizate (TPV). 5. The connector of claim 1, wherein the housing further includes a proximal end and a cap disposed thereon. 6. The connector of claim 1, wherein the stem further includes an interior surface wherein the interior surface defines the fluid passage. 7. The connector of claim 6, wherein the interior surface comprises a halogenated polyolefin. 8. The connector of claim 1, wherein the housing includes an interlocking mechanism configured to matingly engage the complimentary housing. 9. The connector of claim 1, wherein the housing includes at least one tab; and the stem includes at least one groove, wherein the at least one tab and the at least one groove are configured to matingly engage. 10. The connector of claim 1, wherein the at least one seal includes an O-ring. 11. The connector of claim 1, wherein at least a portion of the housing comprises polyvinylidene fluoride or polypropylene. 12. The connector of claim 1, wherein the stem further includes a flange. 13. The connector of claim 12, wherein the flange is configured to abut the housing when the stem engages the complimentary seal structure. 14. A connector comprising: a first housing defining an aperture configured to engage a complimentary second housing of a complimentary connector;a first valve disposed over the aperture, wherein a majority of an innermost surface area of an external surface of the first valve is configured to align with and seal to a majority of an innermost surface area of an external surface of a complimentary second valve when the first housing engages the second housing; anda seal structure having a seal located on an outside diameter of a fluid passage, the seal structure configured to engage a proximal end of a stem of the complimentary connector after the first and second housings engage, wherein the stem has an internal chamber with an open end on the proximal end, a distal end, and a uniform length therebetween, and wherein the stem is configured to move in relation to the second housing and open a path for a fluid to flow between a distal end of the connector positioned furthest from the complimentary connector and a distal end of the complimentary connector positioned furthest from the connector by uniformly engaging the second valve to fold open the first valve and the second valve. 15. The connector of claim 14, wherein the stem of the complimentary connector is configured to move through the first and second valves to engage the seal structure. 16. The connector of claim 15, wherein the first valve is configured to fold with the second valve in a direction of the movement of the stem when the stem moves through the first and second valves. 17. The connector of claim 14, wherein the seal structure includes an O-ring. 18. A sterile connector assembly for mounting on a fluid system comprising: a first connector including: a stem having an internal chamber with an open end on a proximal end, a distal end, and a uniform length therebetween defining a fluid passage therethrough;a first housing surrounding the stem and defining a first aperture; anda first valve disposed over the first aperture; anda second connector including: a second housing configured to matingly engage the first housing, the second housing defining a second aperture and defining a seal structure having a seal located on an outside diameter of a fluid passage, wherein the seal structure is configured to engage the proximal end of the stem; anda second valve disposed over the second aperture, wherein a majority of an innermost surface area of an external surface of the second valve is configured to engage with and seal to a majority of an innermost surface area of an external surface of the first valve when the first housing engages the second housing, wherein the stem is configured to move in relation to the first housing and open a path for a fluid to flow between a distal end of the first connector positioned furthest from the second connector and a distal end of the second connector positioned furthest from the first connector by uniformly engaging the first valve to fold open the first valve and the second valve. 19. The sterile connector assembly of claim 18, having a pressure rating of at least about 50 psi. 20. A fluid system comprising: a first fluid container coupled to a distal end of a first housing of a first connector, wherein a proximal end of the first housing defines a first aperture, a first valve disposed over the first aperture, and wherein the proximal end further defines a seal structure having a seal located on an outside diameter of a fluid passage, wherein the seal structure is configured to engage a proximal end of a stem of a second connector; anda second fluid container coupled to a distal end of the stem of the second connector, the second connector including the stem and a second housing, a proximal end of the second housing configured to matingly engage the first housing; the stem having an internal chamber with an open end on the proximal end and a uniform length therebetween the proximal end and the distal end defining a fluid passage therethrough, the second housing surrounding the stem and defining a second aperture, a second valve disposed over the second aperture, wherein a majority of an innermost surface area of an external surface of the second valve is configured to align with and seal to a majority of an innermost surface area of an external surface of the first valve when the first housing engages the second housing, and wherein the stem is configured to move in relation to the second housing and open a path for a fluid to flow between a distal end of the first connector positioned furthest from the second connector and a distal end of the second connector positioned furthest from the first connector by uniformly engaging the second valve to fold open the first valve and the second valve, and wherein the stem is further configured to engage the seal structure of the first housing after the first and second housings engage. 21. The fluid system of claim 20, wherein the distal end of the first housing and a distal end of the second housing have an outside diameter of about ¼ inch, about ⅜ inch, or about ½ inch.