Implantable heart assist system and method of applying same
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61M-001/10
A61M-001/12
A61M-001/36
A61M-025/00
출원번호
US-0175735
(2011-07-01)
등록번호
US-8900115
(2014-12-02)
발명자
/ 주소
Bolling, Steven F.
Gharib, Morteza
Aldea, Gabriel
Gaddis, Mary Lynn
Viole, Anthony J.
출원인 / 주소
Thoratec Corporation
대리인 / 주소
Knobbe, Martens, Olson & Bear LLP
인용정보
피인용 횟수 :
8인용 특허 :
203
초록▼
An extracardiac pumping for supplementing the circulation of blood, including the cardiac output, in a patient without any component thereof being connected to the patient's heart, and methods of using same. One embodiment provides a vascular graft that has a first end that is sized and configured t
An extracardiac pumping for supplementing the circulation of blood, including the cardiac output, in a patient without any component thereof being connected to the patient's heart, and methods of using same. One embodiment provides a vascular graft that has a first end that is sized and configured to couple to a non-primary blood vessel and a second end that is fluidly coupled to a pump to conduct blood between the pump and the non-primary blood vessel. An outflow conduit is also provided that has a first end sized and configured to be positioned within the same or different blood vessel, whether primary or non-primary, through the vascular graft. The outflow conduit is fluidly coupled to the pump to conduct blood between the pump and the patient. The vascular graft may be connected to the blood vessel subcutaneously to permit application of the extracardiac pumping system in a minimally-invasive procedure.
대표청구항▼
1. A system for supplementing blood circulation in a patient comprising: a pump configured to pump blood through the patient at subcardiac flow rates, said pump having an average flow rate that, during normal operation thereof is substantially below that of the patient's heart when healthy; anda con
1. A system for supplementing blood circulation in a patient comprising: a pump configured to pump blood through the patient at subcardiac flow rates, said pump having an average flow rate that, during normal operation thereof is substantially below that of the patient's heart when healthy; anda conduit fluidly coupled to the pump and configured to withdraw blood from and return blood to the patient's vasculature wherein the blood may travel in reverse directions within the conduit;wherein the pump is configured to be implanted within the patient minimally invasively. 2. The system of claim 1, wherein the pump is selected from the group consisting of a pulsatile pump, a rotary pump, and a continuous flow pump. 3. The system of claim 1, wherein the conduit comprises a first lumen and a second lumen. 4. The system of claim 3, wherein the first and second lumens each comprise a proximal end configured to couple with the pump and a distal end. 5. The system of claim 4, wherein the conduit further comprises an inflow port at the distal end of the first lumen and an outflow port at the distal end of the second lumen. 6. The system of claim 1, wherein the conduit is comprised of a material that is sufficiently flexible so as not to prevent the patient from being ambulatory. 7. A system for supplementing the circulation of blood through a patient, the system comprising: a pulsatile pump configured to be implanted in the patient; anda conduit configured to minimally-invasively couple with a non-primary blood vessel of the circulatory system of the patient and configured for fluid communication with the pulsatile pump, andwherein the system is configured to direct blood from the circulatory system into the conduit to reduce the load on the heart. 8. The system of claim 7, wherein the pump is configured to be implanted extrathoracially in the patient. 9. The system of claim 7, wherein the pump is configured to be implanted subcutaneously in the patient. 10. The system of claim 7, wherein the conduit comprises an inflow port, a first lumen, an outflow port, and a second lumen. 11. The system of claim 10, wherein the conduit is configured to: direct the blood from the vasculature into the first lumen through the inflow port while the heart is in systole; anddirect the blood from the second lumen through the outflow port and into the vasculature while the heart is in diastole. 12. The system of claim 7, wherein the pump is configured to operate out-of-phase with the heart cycle. 13. The system of claim 12, wherein the system is configured to direct blood from the circulatory system into the conduit just prior to isovolumetric contraction. 14. The system of claim 7, wherein the pulsatile pump comprises a rotary pump. 15. A system for supplementing the circulation of blood through a patient, the system comprising: a pulsatile pump configured to be implanted extrathoracially in the patient; anda conduit configured to couple to a peripheral blood vessel of the circulatory system of the patient and configured for fluid communication with the pulsatile pump,wherein the pulsatile pump is configured to intake into or expel blood from the conduit in a manner to reduce the load on the patient's heart during systole. 16. The system of claim 15, wherein the pump is configured to be implanted subcutaneously in the patient. 17. The system of claim 15, wherein the conduit is configured to be coupled to the circulatory system of the patient subcutaneously. 18. The system of claim 15, wherein the conduit is a first conduit comprising a first port and a first lumen. 19. The system of claim 18, wherein the system comprises a second conduit comprising a second port and a second lumen. 20. The system of claim 19, wherein: the first port is an inflow port, the first lumen is an inflow lumen, the second port is an outflow port, and the second lumen is an outflow lumen;the first conduit is configured to direct the blood from the vasculature into the inflow lumen through the inflow port while the heart is in systole; andthe second conduit is configured to direct the blood from the outflow lumen through the outflow port and into the vasculature while the heart is in diastole. 21. The system of claim 15, wherein the conduit comprises a first lumen and a second lumen. 22. The system of claim 15, wherein the conduit is configured to couple to the left subclavian artery of the patient. 23. The system of claim 15, wherein the pump is configured to operate out-of-phase with the heart cycle. 24. The system of claim 23, wherein the pump is configured to intake blood into the conduit just prior to isovolumetric contraction. 25. The system of claim 15, wherein the pulsatile pump comprises a rotary pump. 26. A system for supplementing the circulation of blood through a patient using counterpulsation, the system comprising: a pulsatile pump configured to be implanted extrathoracially in the patient;a conduit configured to couple to the circulatory system of the patient and configured for fluid communication with the pulsatile pump,wherein the pulsatile pump is configured to operate in a counter-pulsating manner to reduce the load on the patient's heart during systole; anda continuous flow pump configured to be operated in parallel with the pulsatile pump.
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