The present invention relates to an intra-oral device including a carrier that has an outside wall, an inside wall and an occlusal wall connecting the outside wall to the inside wall. The carrier has at least one inset and at least one insert carrying a beneficial agent that is adapted to fit the in
The present invention relates to an intra-oral device including a carrier that has an outside wall, an inside wall and an occlusal wall connecting the outside wall to the inside wall. The carrier has at least one inset and at least one insert carrying a beneficial agent that is adapted to fit the inset, and the beneficial agent is capable of promoting weight loss. The intra-oral device is positioned in a user's mouth so that the intra-oral device is in contact with the user's cheeks, lips and/or tongue and the beneficial agent passes through the mucosal membrane of the user's mouth.
대표청구항▼
1. A method of administering a beneficial agent to promote weight loss or weight management in humans comprising: instead of eating, positioning an intra-oral device over an arch of teeth of a user when said user has a desire to eat;wherein said intra-oral device includes a carrier having an outside
1. A method of administering a beneficial agent to promote weight loss or weight management in humans comprising: instead of eating, positioning an intra-oral device over an arch of teeth of a user when said user has a desire to eat;wherein said intra-oral device includes a carrier having an outside wall, an inside wall, and an occlusal wall connecting said outside wall to said inside wall; and wherein said intra-oral device contains a beneficial agent for promoting weight loss or weight management selected from the group consisting of flavors, odors, appetite suppressants, agents for decreasing food absorption, agents for absorbing dietary fat, herbal compounds, chemicals, therapeutic agents, medications, pharmaceuticals, nutraceuticals and combinations thereof. 2. The method of claim 1, further comprising: removing said intra-oral device from said user's mouth when said beneficial agent extinguishes said user's desire to eat. 3. The method of claim 1, wherein said beneficial agent is flavors, odors, and a combination of flavors and odors. 4. The method of claim 3, further comprising exposing said intra-oral device to a solution comprising said beneficial agent before positioning said intra-oral device over said arch of teeth of said user. 5. The method of claim 4, wherein said step of exposing said intra-oral device to a solution comprises soaking said intra-oral device in said solution until said intra-oral device is imbibed with said solution. 6. The method of claim 3, further comprising replenishing said beneficial agent in said intra-oral device. 7. The method of claim 6, wherein said step of replenishing beneficial agent comprises soaking said intra-oral device in said solution until said intra-oral device is imbibed with said solution. 8. The method of claim 1, wherein said beneficial agent has time release properties. 9. The method of claim 1, wherein said carrier has at least one inset and at least one insert adapted to fit said inset, said insert carrying said beneficial agent. 10. The method of claim 1, wherein said beneficial agent is released by a delivery system comprising a hydrogel. 11. The method of claim 1, wherein said carrier includes at least one perforation. 12. The method of claim 11, further comprising applying pressure to said intra-oral device with said user's tongue to cause a discharge of said beneficial agent through said perforation. 13. The method of claim 1, wherein said beneficial agent is released by a delivery system comprising pullulan. 14. The method of claim 1, wherein said outside wall, said inside wall, and said occlusal wall of said carrier define at least one channel for embracing said arch of teeth; said carrier having a right-hand portion for embracing a portion of said arch of teeth on a right side of said user's mouth and a left-hand portion for embracing a portion of said arch of teeth on a left side of said user's mouth, and said carrier having an intermediate portion disposed between said right-hand portion and said left-hand portion and extending along at least a portion of said user's palate, wherein said intermediate portion carries said beneficial agent. 15. The method of claim 14, wherein said intermediate portion includes at least one inset and at least one insert adapted to fit said inset, said insert carrying said beneficial agent. 16. The method of claim 14, wherein said intermediate portion comprises a wing extending from said inside wall. 17. The method of claim 16, wherein said wing includes at least one inset and at least one insert adapted to fit said inset, said insert carrying said beneficial agent. 18. The method of claim 1, wherein said outside wall is provided with an opening adapted to expose at least one of said user's teeth. 19. A method of administering a beneficial agent to promote weight loss or weight management in humans comprising: positioning an intra-oral device over an arch of teeth of a user when said user has a desire to eat; wherein said intra-oral device includes a carrier having an outside wall, an inside wall, and an occlusal wall connecting said outside wall to said inside wall; wherein said outside wall is provided with an opening adapted to expose at least one of said user's teeth; and wherein said intra-oral device contains a beneficial agent for promoting weight loss or weight management selected from the group consisting of flavors, odors, appetite suppressants, agents for decreasing food absorption, agents for absorbing dietary fat, herbal compounds, chemicals, therapeutic agents, medications, pharmaceuticals, and nutraceuticals. 20. A method of administering a beneficial agent to promote weight loss or weight management in humans comprising: positioning an intra-oral device over an arch of teeth of a user when said user has a desire to eat; wherein said intra-oral device includes a carrier having an outside wall, an inside wall and an occlusal wall connecting said outside wall to said inside wall; wherein said intra-oral device contains a beneficial agent for promoting weight loss or weight management selected from the group consisting of flavors, odors, appetite suppressants, agents for decreasing food absorption, agents for absorbing dietary fat, herbal compounds, chemicals, therapeutic agents, medications, pharmaceuticals, and nutraceuticals; and wherein said outside wall, said inside wall, and said occlusal wall of said carrier define at least one channel for embracing said arch of teeth; said carrier having a right-hand portion for embracing a portion of said arch of teeth on a right side of said user's mouth and a left-hand portion for embracing a portion of said arch of teeth on a left side of said user's mouth, and said carrier having an intermediate portion disposed between said right-hand portion and said left-hand portion and extending along at least a portion of said user's palate, wherein said intermediate portion carries said beneficial agent. 21. The method of claim 20, wherein said intermediate portion includes at least one inset and at least one insert adapted to fit said inset, said insert carrying said beneficial agent. 22. The method of claim 20, wherein said intermediate portion comprises a wing extending from said inside wall. 23. The method of claim 22, wherein said wing includes at least one inset and at least one insert adapted to fit said inset, said insert carrying said beneficial agent.
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이 특허에 인용된 특허 (68)
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