The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
대표청구항▼
1. An electronic device for processing sensor data from a subcutaneous continuous glucose sensor, the device comprising: a processor module configured to process sensor data from a subcutaneous continuous glucose sensor, the sensor data comprising a plurality of sensor data points; anda computer rea
1. An electronic device for processing sensor data from a subcutaneous continuous glucose sensor, the device comprising: a processor module configured to process sensor data from a subcutaneous continuous glucose sensor, the sensor data comprising a plurality of sensor data points; anda computer readable memory comprising: instructions configured to cause the processor module to determine a rate of change of the sensor data; andinstructions comprising a threshold rate of about 4 mg/dL/min, wherein the instruction are configured to allow the processor module to calibrate the sensor data using a reference glucose measurement when the rate of change is less than the threshold rate, but not allow the processor module to calibrate the sensor data using the reference glucose measurement when the rate of change is greater than the threshold rate. 2. The device of claim 1, wherein the calibration is based on a matched data pair formed by matching a sensor data point of the sensor data with the reference glucose measurement. 3. The device of claim 1, wherein the instructions configured to allow the processor module to calibrate the sensor data comprise instructions configured to cause the processor module to compensate for a time lag between the reference glucose measurement and a time-corresponding sensor data point. 4. The device of claim 1, wherein the instructions configured to allow the processor module to calibrate the sensor data comprise instructions configured to cause the processor module to evaluate the sensor data to determine a sensor break-in and to request the reference glucose measurement in response to the sensor break-in determination. 5. The device of claim 1, wherein the reference glucose measurement is obtained from a reference glucose monitor operatively and/or physically coupled to the electronic device. 6. The device of claim 1, wherein the instructions configured to allow the processor module to calibrate the sensor data comprise instructions configured to cause the processor module to determine a best matched data pair from a plurality of matched data pairs, wherein the plurality of matched data pairs comprise the reference glucose measurement matched with a plurality of individual sensor data points. 7. The device of claim 1, wherein the instructions configured to cause the processor module to calibrate the sensor data comprise instructions configured to cause the processor module to evaluate a clinical acceptability of the reference glucose measurement and a time-corresponding sensor data point based on a deviation of the time-corresponding sensor data point from the reference glucose measurement and a clinical risk associated with the deviation based on the glucose concentration indicated by the reference glucose measurement or the sensor data point. 8. The device of claim 7, wherein the instructions configured to cause the processor module to evaluate a clinical acceptability are based on a clinical error grid. 9. The device of claim 8, wherein the clinical error grid is a Clarke error grid. 10. The device of claim 1, wherein the sensor data is indicative of the concentration of glucose in a subcutaneous space of the host. 11. The device of claim 1, wherein the computer readable memory further comprises instructions configured to cause the processor module to prospectively calibrate the sensor data when calibration is allowed. 12. The device of claim 1, wherein the rate of change is calculated using calibrated sensor data. 13. The device of claim 1, wherein the computer readable memory further comprises instructions configured to cause the processor module to calculate real-time glucose concentration values based on the calibrated sensor data. 14. The device of claim 13, further comprising a user interface, wherein the computer readable memory further comprises instructions configured to cause the processor module to initiate display, on the user interface, of real-time glucose concentration information based on the calculated real-time glucose concentration values. 15. The device of claim 1, further comprising instructions configured to cause the processor module to estimate at least one projected glucose concentration value based at least in part on a linear extrapolation of calibrated sensor data and on a variation analysis. 16. The device of claim 15, further comprising instructions configured to cause the processor module to activate an alarm when a projected glucose concentration value is greater than a high threshold value or less than a low threshold value. 17. An electronic device for processing sensor data from a subcutaneous continuous glucose sensor, the device comprising: a processor module configured to process sensor data from a subcutaneous continuous glucose sensor, the sensor data comprising a plurality of sensor data points; anda computer readable memory comprising: instructions configured to cause the processor module to determine a rate of change of the sensor data; andinstructions configured to cause the processor module to evaluate the rate of change of the sensor data against an acceptability criterion a threshold rate of 3.5 mg/dL/min. to determine whether a reference glucose measurement is acceptable for calibration of the sensor data, wherein the acceptability criterion allows for the instructions allow for calibration of the sensor data using the reference glucose measurement when the rate of change of the sensor data less than 3.5 mg/dL/min the threshold rate, but does not allow for calibration of the sensor data using the reference glucose measurement when the rate of change of the sensor data is above 3.5 mg/dL the threshold rate. 18. The device of claim 17, wherein the calibration is based on a matched data pair formed by matching a sensor data point of the sensor data with the reference glucose measurement. 19. The device of claim 17, further comprising instructions configured to cause the processor module to compensate for a time lag between the reference glucose measurement and a time-corresponding sensor data point. 20. The device of claim 17, further comprising instructions configured to cause the processor module to evaluate the sensor data to determine a sensor break-in and to request the reference glucose measurement in response to the sensor break-in determination. 21. The device of claim 17, wherein the reference glucose measurement is obtained from a reference glucose monitor operatively and/or physically coupled to the electronic device. 22. The device of claim 17, further comprising instructions configured to cause the processor module to determine a best matched data pair from a plurality of matched data pairs, wherein the plurality of matched data pairs comprise the reference glucose measurement matched with a plurality of individual sensor data points. 23. The device of claim 17, further comprising instructions configured to cause the processor module to evaluate a clinical acceptability of the reference glucose measurement and a time-corresponding sensor data point based on a deviation of the time-corresponding sensor data point from the reference glucose measurement and a clinical risk associated with the deviation based on the glucose concentration indicated by the reference glucose measurement or the sensor data point. 24. The device of claim 23, wherein the instructions configured to cause the processor module to evaluate a clinical acceptability are based on a clinical error grid. 25. The device of claim 24, wherein the clinical error grid is a Clarke error grid. 26. The device of claim 17, wherein the sensor data is indicative of the concentration of glucose in a subcutaneous space of the host. 27. The device of claim 17, wherein the computer readable memory further comprises instructions configured to cause the processor module to prospectively calibrate the sensor data when calibration is allowed. 28. The device of claim 17, wherein the rate of change is calculated using calibrated sensor data. 29. The device of claim 17, wherein the computer readable memory further comprises instructions configured to cause the processor module to calculate real-time glucose concentration values based on the calibrated sensor data. 30. The device of claim 29, further comprising a user interface, wherein the computer readable memory further comprises instructions configured to cause the processor module to initiate display, on the user interface, of real-time glucose concentration information based on the calculated real-time glucose concentration values.
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Purcell William P., 9-cis retinoic acid esters and amides and uses thereof.
Hou Kenneth C. (Glastonbury CT) Liao Tung-Ping D. (Missouri City TX) Rohan Robert (Columbia CT), Affinity matrices of modified polysaccharide supports.
Starkweather, Timothy J.; Lebel, Ronald J.; Shahmirian, Varaz; Weiss, Philip T.; Marsh, David J., Ambulatory medical apparatus and method having telemetry modifiable control software.
Lebel, Ronald J.; Shahmirian, Varaz; Bowman, IV, Sam W.; Dennard, Robert C.; Armstrong, John T.; Richert, John D., Ambulatory medical apparatus and method using a robust communication protocol.
Lebel, Ronald J.; Shahmirian, Varaz; Starkweather, Timothy J.; Weiss, Philip T.; Villegas, Daniel H.; Dennard, Robert C.; Armstrong, John T.; Richert, John D., Ambulatory medical apparatus and method using a telemetry system with predefined reception listening periods.
Lebel, Ronald J.; Shahmirian, Varaz; Starkweather, Timothy J.; Villegas, Daniel H.; Choy, David Y.; Weiss, Philip T.; Chong, Colin A.; Lord, Peter C.; Morgan, Wayne A.; Meadows, Paul M., Ambulatory medical apparatus with hand held communication device.
Lebel, Ronald J.; Shahmirian, Varaz; Villegas, Daniel H.; Choy, David Y.; Weiss, Philip T.; Meadows, Paul M., Ambulatory medical apparatus with hand held communication device.
Say James ; Tomasco Michael F. ; Heller Adam ; Gal Yoram,ILX ; Aria Behrad ; Heller Ephraim ; Plante Phillip John ; Vreeke Mark S. ; Friedman Keith A. ; Colman Fredric C., Analyte monitoring device and methods of use.
Causey ; III James D. ; Kovelman Paul H. ; Purvis Richard E. ; Mastrototaro John J., Analyte sensor and holter-type monitor system and method of using the same.
Hans Kintzig DE; Michael Schabbach DE; Hans-Ruediger Murawski DE; Wolfgang Obermeier DE; Karl Miltner DE, Analytical measuring device with lancing device.
Bcker Dirk (Heidelberg DEX) Haar Hans-Peter (Wiesloch DEX) Blasberg Peter (Weinheim DEX) Kotulla Reinhard (Lambsheim DEX), Analytical system for monitoring a substance to be analyzed in patient-blood.
Robinson,Mark Ries; Fleming,Cliona; Jones,Howland; Rohrscheib,Mark, Apparatus and method for non-invasive spectroscopic measurement of analytes in tissue using a matched reference analyte.
Fuller Milton E. (500 Winchester Dr. Reno NV 89506) Cherne Frank J. (1295 Wesley Dr. Reno NV 89503), Apparatus and method for radio frequency spectroscopy using spectral analysis.
Lovejoy David A. (Waukesha WI) Young Robert L. (Waukesha WI) Heinzelman Bert D. (Tenafly NJ), Apparatus for determining spectral absorption by a specific substance in a fluid.
Nishikawa Hisao,JPX ; Sonoda Kouichi,JPX ; Takinami Masao,JPX ; Morikawa Naoki,JPX, Assembly having lancet and means for collecting and detecting body fluid.
Blackburn Gary ; Creager Stephen E. ; Fraser Scott ; Irvine Bruce D. ; Meade Thomas J. ; O'Connor Stephen D. ; Terbrueggen Robert H. ; Vielmetter Jost G. ; Welch Thomas W., Binding acceleration techniques for the detection of analytes.
Della Valle Francesco (Padua ITX) Calderini Gabriella (Carrara San Giorgio ITX) Rastrelli Alessandro (Padua ITX) Romeo Aurelio (Rome ITX), Biocompatible perforated membranes, processes for their preparation, their use as a support in the in vitro growth of ep.
White Bradley E. (Indianapolis IN) Parks Robert A. (Springport IN) Ritchie Paul G. (Indianapolis IN) Svetnik Vladimir (Carmel IN), Biosensing meter with fail/safe procedures to prevent erroneous indications.
Cunningham David D. (Lakemoor IL) Brontman Susan B. (Buffalo Grove IL) Geist Jill M. (Ingleside IL) Helgren R. Hayes (Mundelein IL) Henning Timothy P. (Vernon Hills IL) Johnson Kenneth S. (Buffalo Gr, Biosensor with a membrane containing biologically active material.
Shaffer Thomas H. (Lansdowne PA) Wolfson Marla R. (Philadelphia PA) Miller Thomas F. (Philadelphia PA) Foust ; III Raymond (Philadelphia PA), Breathable liquid elimination analysis.
Simons Tad Decatur ; Greenstein Michael ; Freeman Dominique ; Leonard Leslie Anne ; King David A. ; Lum Paul, Cassette of lancet cartridges for sampling blood.
Steil, Garry M.; Rebrin, Kerstin; Goode, Jr., Paul V.; Mastrototaro, John J.; Purvis, Richard E.; Van Antwerp, William P.; Shin, John J.; Talbot, Cary D., Closed loop system for controlling insulin infusion.
Clarke Robert A (Libertyville IL) Pauley Robin G. (Ingleside IL) Hill Ronald S. (Grayslake IL) Brauker James H. (Harvard IL) Sternberg Shmuel (Northbrook IL) Boggs Daniel R. (Libertyville IL), Closed porous chambers for implanting tissue in a host.
Clarke Robert A. (Libertyville IL) Pauley Robin G. (Ingleside IL) Hill Ronald S. (Grayslake IL) Brauker James H. (Harvard IL) Sternberg Shmuel (Northbrook IL) Boggs Daniel R. (Libertyville IL), Closed porous chambers for implanting tissue in a host.
Malave, Luis J.; Estes, Mark C.; Yonemoto, Jay; Barlow, J. Jeffrey; Gross, Todd M.; Shin, John; Cheney, II, Paul S.; Dobbles, Mike; Hague, Clifford W.; Ruppert, Deborah; Wells, Kevin C., Communication station and software for interfacing with an infusion pump, analyte monitor, analyte meter, or the like.
Gough David A. (Cardiff CA) Lucisano Joseph Y. (La Jolla CA) Armour Jon C. (La Jolla CA) McKean Brian D. (San Diego CA), Complete glucose monitoring system with an implantable, telemetered sensor module.
Routh Helen F. (Kirkland WA) Powrie ; Jr. Charles W. (Bellevue WA) Peterson Roy B. (Redmond WA), Continuous display of peak and mean blood flow velocities.
Oweis Salah ; Zatorski Raymond A. ; Chagnon Guy ; Rigobert Gerard,FRX ; Souliac Laurent,FRX, Current collection through thermally sprayed tabs at the ends of a spirally wound electrochemical cell.
Faupel Mark L. (Conyers GA) Barrett Burke T. (Roswell GA) Stephens John D. (Alpharetta GA) Nathanson Seth D. (Alpharetta GA), D.C. biopotential sensing electrode assemblies for apparatus for disease, injury and bodily condition screening or sensi.
Ham Fredric M. (Indialantic FL) Cohen Glenn M. (Indialantic FL), Determination of concentrations of biological substances using raman spectroscopy and artificial neural network discrimi.
Gross Joseph,ILX ; Reingewirtz Meir,ILX ; Katz Moshe George,ILX, Device and method of calibrating and testing a sensor for in vivo measurement of an analyte.
Penn, Richard D.; Miesel, Keith Alan; Stylos, Lee; Christopherson, Mark A.; Nagavarapu, Sudha; Roline, Glenn M., Device and method to measure and communicate body parameters.
Bret Berner ; Chia-Ming Chiang ; Michael D. Garrison ; Janan Jona ; Russell O. Potts ; Janet A. Tamada ; Michael J. Tierney, Device for monitoring of physiological analytes.
Berner, Bret; Dunn, Timothy C.; Farinas, Kathleen C.; Garrison, Michael D.; Kurnik, Ronald T.; Lesho, Matthew J.; Potts, Russell O.; Tamada, Janet A.; Tierney, Michael J., Device for signal processing for measurement of physiological analytes.
Conn, Thomas E.; Ford, Russell; Potts, Russell O.; Soni, Pravin L.; Tamada, Janet A.; Tierney, Michael J., Devices and methods for frequent measurement of an analyte present in a biological system.
Say James ; Tomasco Michael F. ; Heller Adam ; Gal Yoram,ILX ; Aria Behrad ; Heller Ephraim ; Plante Phillip John ; Vreeke Mark S., Electrochemical analyte.
James Say ; Michael F. Tomasco ; Adam Heller ; Yoram Gal IL; Behrad Aria ; Ephraim Heller ; Phillip John Plante ; Mark S. Vreeke, Electrochemical analyte sensor.
Carter Nigel F. (Oxon GB2) Chambers Geoffrey R. (Northwood Middlesex GB2) Hughes Graham J. (Oxford GB2) Scott Steven (Oxon GB2) Sanghera Gurdial S. (Oxford GB2) Watkin Jared L. (Oxon GB2), Electrochemical sensor.
Maley Thomas C. (Medway MA) D\Orazio Paul A. (Mendon MA) Dalzell Bonnie C. (Sherborn MA) Edelman Peter G. (Franklin MA) Flaherty James E. (Attleboro MA) Mason Richard W. (Millis MA) McCaffrey Robert , Electrochemical sensors.
Stafford Rodney A. (Ballyross Glencree ; County Wicklow IEX) Kilroy Michael M. (Castlecor Oldcastle ; County Meath IEX), Electronic animal identification system.
Banauch Dieter (Darmstadt DT) Brummer Wolfgang (Darmstadt DT) Ebeling Wolfgang (Darmstadt DT) Helger Roland (Darmstadt DT) Hennrich Norbert (Darmstadt DT) Lang Hermann (Darmstadt DT), Enzymatic determination of glucose.
Rishpon Judith (Los Alamos NM) Zawodzinski Thomas A. (Los Alamos NM) Gottesfeld Shimshon (Los Alamos NM), Enzyme electrochemical sensor electrode and method of making it.
D\Orazio Paul A. (Mishawaka IN) Eddy ; Jr. Arthur R. (Depew NY) Fogt Eric J. (Maple Grove MN) Jones James E. (Elkhart IN) Oberhardt Bruce J. (Mishawaka IN), Enzyme electrode membrane.
Gregg Brian A. (13940 Braun Dr. Golden CO 80401) Heller Adam (5317 Valburn Cir. Austin TX 78731) Kerner Wolfgang (Universitat Zu Lubeck ; Klinik Fur Innerere Medizin ; Razeburger Allee 160 D-2400 Lub, Enzyme electrodes.
Lord Peter C. (Santa Clarita CA) Van Antwerp William P. (Brentwood CA) Mastrototaro John J. (Los Angeles CA) Cheney ; II Paul S. (Beverly Hills CA) Schnabel Nannette M. (Valencia CA), Flex circuit connector.
Savage Douglas R. (Del Mar CA) Betts Ronald E. (La Jolla CA) Koerner Richard J. (San Diego CA) Hillier Douglas R. (San Juan Capistrano CA), Fluid sample analyte collector and calibration assembly.
Schulman Joseph H. (10650 Comet Way Santa Clarita CA 91351) Rule ; III Orville R. (2572 Basil La. Los Angeles CA 90077), Fluidic infusion system for catheter or probe.
Ford, Russell; Lesho, Matthew J.; Potts, Russell O.; Tierney, Michael J.; Wei, Charles W., Formulation and manipulation of databases of analyte and associated values.
Francis Moussy ; Robert W. Conlan ; Markham C. Godwin ; Richard D. Beach, Generic integrated implantable potentiostat telemetry unit for electrochemical sensors.
Young Chung C. (Weston MA) Gary Kenneth (Belmont MA) Winarta Handani (Waltham MA) Chen Chin-Chun (Wayland MA), Glucose electrode and method of determining glucose.
Garcia Fernando S. (Eden Prairie MN) Merkert Hartmut G. (Eden Prairie MN) Anderson Paul J. (Eden Prairie MN) Linde David E. (Eden Prairie MN) Hudson Bertram J. (Eden Prairie MN), Glucose medical monitoring system.
Schulman Joseph H. (Santa Clarita CA) Rule ; III Orville R. (Los Angeles CA) Whitmoyer David I. (Los Angeles CA) Lebel Ronald J. (Sherman Oaks CA) Lucisano Joseph Y. (Saugus CA) Mann Alfred E. (Bever, Glucose monitoring system.
Schulman Joseph H. (Santa Clarita CA) Rule ; III Orville Rey (Los Angeles CA) Whitmoyer David I. (Los Angeles CA) Lebel Ronald J. (Sherman Oaks CA) Lucisano Joseph Y. (Saugus CA) Mann Alfred E. (Beve, Glucose sensor assembly.
K. Collin McIvor ; James L. Cabernoch ; Kevin D. Branch ; Nannette M. Van Antwerp ; Edgardo C. Halili ; John J. Mastrototaro, Glucose sensor package system.
McIvor, K. Collin; Cabernoch, James L.; Branch, Kevin D.; Van Antwerp, Nannette M.; Halili, Edgardo C.; Mastrototaro, John J., Glucose sensor package system.
McIvor, K. Collin; Cabernoch, James L.; Branch, Kevin D.; Van Antwerp, Nannette M.; Halili, Edgardo C.; Mastrototaro, John J., Glucose sensor package system.
Keogh Philip L. (Pittsford NY) Kunzler Jay F. (Canadaigua NY) Niu Gregory C. C. (Lexington MA), Hydrophilic contact lens made from polysiloxanes which are thermally bonded to polymerizable groups and which contain hy.
Allen Douglas J. (Indianapolis IN) Johnson Kirk W. (Indianapolis IN) Nevin Robert S. (Indianapolis IN), Hydrophilic polyurethane membranes for electrochemical glucose sensors.
Dionne Keith E. ; Emerich Dwaine F. ; Hoffman Diane ; Sanberg Paul R. ; Christenson Lisa ; Hegre Orion D. ; Scharp David W. ; Lacy Paul E. ; Aebischer Patrick,CHX ; Vasconcellos Alfred V. ; Lysaght M, Implantable biocompatable immunoisolatory vehicle for delivery of selected therapeutic products.
Slater Charles R. ; Jahrmarkt Scott L. ; Smith Scott T. ; Smith Kevin W., Implantable brachytherapy device having at least partial deactivation capability.
Joseph H. Schulman ; Charles L. Byers ; Gerald E. Adomian ; Michael S. Colvin, Implantable enzyme-based monitoring systems having improved longevity due to improved exterior surfaces.
Schulman Joseph H. ; Byers Charles L. ; Adomian Gerald E. ; Colvin Michael S., Implantable enzyme-based monitoring systems having improved longevity due to improved exterior surfaces.
Bessman Samuel P. (2025 Zonal Ave. Los Angeles CA 90033) Layne Ennis C. (9128 Huntington Dr. San Gabriel CA 91775) Thomas Lyell J. (1900 Pelican Ave. San Pedro CA 90732), Implantable glucose sensor.
Wilson George S. (Lawrence KS) Bindra Dilbir S. (Lawrence KS) Hill Brian S. (Lawrence KS) Thevenot Daniel R. (Paris Cedex FRX) Sternberg Robert (Thiais FRX) Reach Gerard (Paris Cedex KS FRX) Zhang Ya, Implantable glucose sensor.
Gosserez Olivier (Quartier Didier Alle de la Louisiane 97200 Fort de France ; Martinique FRX), Implantable mammary prosthesis adapted to combat the formation of a retractile shell.
Andrews Winston A. (Danville CA) Nelson David (San Jose CA) Novy Richard W. (Sunnyvale CA), Implantable prosthesis with open cell textured surface and method for forming same.
Dai Sheng ; Burleigh Mark C. ; Shin Yongsoon, Imprint-coating synthesis of selective functionalized ordered mesoporous sorbents for separation and sensors.
Kimball Victor E. ; Lynch Laurie E. ; Pierskalla Irvin T. ; Porter Christopher H., In situ calibration system for sensors located in a physiologic line.
Fox ; Jr. Charles L. (New York NY) Modak Shanta M. (River Edge NJ) Sampath Lester A. (Nyack NY), Infection-resistant compositions, medical devices and surfaces and methods for preparing and using same.
Bobroff, Randa M.; Kiliszewski, Lawrence; Lickliter, Hans; Houghton, Frederick C.; Safabash, Jason H.; McConnell, Susan M.; Marano, April A., Insertion device for an insertion set and method of using the same.
Safabash Jason H. ; McConnell Susan M. ; Adair Randy W. ; Funderburk Jeffery V. ; Marano April A. ; Field Jeffrey F., Insertion device for an insertion set and method of using the same.
Safabash,Jason H.; McConnell,Susan M.; Adair,Randy W.; Funderbunk,Jeffery V.; Marano,April A.; Field,Jeffrey F., Insertion device for an insertion set and method of using the same.
Safabash,Jason H.; McConnell,Susan M.; Adair,Randy W.; Funderburk,Jeffery V.; Marano,April A.; Field,Jeffrey F., Insertion device for an insertion set and method of using the same.
Brauker, James H.; Tapsak, Mark A.; Saint, Sean T.; Kamath, Apurv U.; Neale, Paul V.; Simpson, Peter C.; Mensinger, Michael Robert; Markovic, Dubravka, Integrated delivery device for continuous glucose sensor.
D\Angelo Joseph P. (Miami FL) Schur Henry B. (Miami FL) Han Kedu (Miami FL) Glenn Daniel J. (Hollywood FL), Integrated system for biological fluid constituent analysis.
Gravel Marian ; Gasparello Benjamin ; Ferraro Joseph ; Sharma Ashutosh ; Strowe Robert John ; Bendek Antonio A. ; Uschold Robert C. ; Antoshkiw William Thomas, Integrated system including medication delivery pen, blood monitoring device, and lancer.
Erickson Brian J. (Woodbury MN) Hilgers Michael E. (Roseville MN) Hendrickson Tracy A. (Minnetonka MN) Shapland J. Edward (Shoreview MN) Solomon Frank A. (Plymouth MN) Knudson Mark B. (Shoreview MN), Interstitial fluid collection and constituent measurement.
Chan Eddie K. M. (Round Lake Beach IL) Pauley Robin G. (Ingleside IL) Brauker James H. (Harvard IL) Woo Lecon (Libertyville IL), Laminated barriers for tissue implants.
Denen Dennis J. (Columbus OH) Eggers Philip E. (Dublin OH) Shaw Robert F. (San Francisco CA) Weller ; III Albert E. (Columbus OH), Local in-device memory feature for electrically powered medical equipment.
Say, James L.; Sakslund, Henning; Tomasco, Michael F.; Audett, Jay D.; Cho, Hyun; Yamasaki, Duane O.; Heller, Adam, Mass transport limited in vivo analyte sensor.
Versteeg Vera A. (Rochester NY) Avedisian C. Thomas (Ithaca NY) Raj Rishi (Ithaca NY), Method and apparatus for CVD using liquid delivery system with an ultrasonic nozzle.
Pfeiffer Ernst (Stauffenbergstr. 34 89075 Ulm DEX) Sternberg Fabio (Robert-Stolz-Str. 17 89231 Neu-Ulm DEX), Method and apparatus for continuously monitoring the concentration of a metabolyte.
Houck Raymond K. ; Koebler Douglas J. ; Williams Glen P. ; Levy Joseph M. ; Danielson Victor G., Method and apparatus for determination of analyte concentration.
Reinhart Richard (Lawrenceville NJ) Letterio Fred (Philadelphia PA) Pugliese Peter (Bernville PA) Ritter Carl (Aldan PA) Lubrano Glenn (Metairie LA) Guilbault Jerry (Slidell LA) Feistel Christopher (, Method and apparatus for measuring blood glucose concentration.
Cunningham David D. ; Henning Timothy P. ; Shain Eric B. ; Young Douglas F. ; Muetterties Andrew J. ; Schapira Thomas G. ; Chambers Geoffrey R.,GBX ; Hughes Graham J.,GBX ; Watkin Jared L.,GBX ; Prok, Method and apparatus for obtaining blood for diagnostic tests.
Pizziconi Vincent B. (3535 E. Highline Canal Rd. Phoenix AZ 85040) Towe Bruce C. (2331 S. Paseo Loma Cir. Mesa AZ 85202), Method and apparatus for withdrawing, collecting and biosensing chemical constituents from complex fluids.
Monfre,Stephen L.; Hazen,Kevin H.; Ruchti,Timothy L.; Blank,Thomas B.; Henderson,James R., Method and apparatus using alternative site glucose determinations to calibrate and maintain noninvasive and implantable analyzers.
Dunn, Timothy C.; Jayalakshmi, Yalia; Kurnik, Ronald T.; Lesho, Matthew J.; Oliver, Jonathan James; Potts, Russell O.; Tamada, Janet A.; Waterhouse, Steven Richard; Wei, Charles W., Method and device for predicting physiological values.
Dunn, Timothy C; Jayalakshmi, Yalia; Kurnik, Ronald T; Lesho, Matthew J; Oliver, Jonathan James; Potts, Russell O; Tamada, Janet A; Waterhouse, Steven Richard; Wei, Charles W, Method and device for predicting physiological values.
Kurnik Ronald T. ; Oliver Jonathan James ; Potts Russell O. ; Waterhouse Steven Richard ; Dunn Timothy C. ; Jayalakshmi Yalia ; Lesho Matthew J. ; Tamada Janet A. ; Wei Charles W., Method and device for predicting physiological values.
Luong John H. T. (Mount Royal CAX) Male Keith B. (Pierrfonds CAX) Cattaneo Maurice V. (Outremont CAX), Method and system for determining bioactive substances.
Hayter, Gary; Budiman, Erwin S.; Doniger, Kenneth J.; Mazza, John C., Method and system for dynamically updating calibration parameters for an analyte sensor.
Neuenfeldt Steven (Vernon Hills IL) Brauker James (Lake Villa IL) Clarke Robert (Libertyville IL) Carr-Brendel Victoria (Woodstock IL), Method for implanting tissue in a host.
Yacynych Alexander (2 Bernard Rd. East Brunswick NJ 08816), Method for making electrochemical sensors and biosensors having a polymer modified surface.
Richardson Charles A. (San Francisco CA) Bernstein Michael (San Ramon CA) Okikawa Jerry K. (Oakland CA) Bennett Terrence R. (Richmond CA), Method for reducing ambient noise effects in electronic monitoring instruments.
Genshaw Marvin A. (Elkhart IN) Huang Dijia (Granger IN) Musho Matthew K. (Granger IN) Yip Kin Fai (Elkhart IN), Method for reducing bias in amperometric sensors.
Khalil, Omar S.; Yeh, Shu-jen; Hanna, Charles F.; Kantor, Stanislaw, Method for the non-invasive determination of analytes in a selected volume of tissue.
Zhang, Zhiwei; Park, Chi-Kyun; Sun, Lu Ying; Chai, Chul, Method of making an electrochemical cell by the application of polysiloxane onto at least one of the cell components.
Tietje-Girault Jordis (1088 Ropraz En Vernay CHX) Seddon Brian J. (Chemin De Fonadel 37 Prilly ; Lausanne ; CH1008 CHX) McAleer Jerome F. (52 Nobles ; Grove Wantage ; Oxfordshire OX12 ONR GBX), Method of making gas permeable membranes for amperometric gas electrodes.
Richard W. Mason ; Rudolf E. Slovacek ; Kevin J. Sullivan, Method of operating an optical sensor adapted for selective analyte-sensing contact with a plurality of samples.
Desai,Shashi P.; Dunn,Timothy C.; Lesho,Matthew J.; Potts,Russell O.; Tamada,Janet A.; Wei,Charles W., Methods for computing rolling analyte measurement values, microprocessors comprising programming to control performance of the methods, and analyte monitoring devices employing the methods.
Mosbach Klaus,SEX ; Cormack Peter A. G.,GBX ; Ramstrom Olof,SEX ; Haupt Karsten,FRX, Methods for direct synthesis of compounds having complementary structure to a desired molecular entity and use thereof.
Martinson Laura A. (Lake Villa IL) Brauker James H. (Lake Villa IL) Johnson Robert C. (Bartlett IL) Loudovaris Thomas (Grayslake IL), Methods for enhancing vascularization of implant devices.
Desai, Shashi P.; Dunn, Timothy C.; Lesho, Matthew J.; Potts, Russell O.; Tamada, Janet A.; Wei, Charles W., Methods for estimating analyte-related signals, microprocessors comprising programming to control performance of the methods, and analyte monitoring devices employing the methods.
Parris, Norman A.; Potts, Russell O.; Tierney, Michael J.; Uhegbu, Christopher, Methods for measuring analyte in a subject and/or compensating for incomplete reaction involving detection of the analyte.
Bartkowiak, Miroslaw; Harper, Wesley S.; Kulcu, Eray; Lesho, Matthew J.; Tamada, Janet A., Micropressors, devices and methods for use in analyte monitoring systems.
Lebel, Ronald J.; Shahmirian, Varaz; Bowman, IV, Sam W.; Starkweather, Timothy J.; Morgan, Wayne A., Microprocessor controlled ambulatory medical apparatus with hand held communication device.
Dunn Timothy C. ; Jayalakshmi Yalia ; Kurnik Ronald T. ; Lesho Matthew J. ; Oliver Jonathan James ; Potts Russell O. ; Tamada Janet A. ; Waterhouse Steven Richard ; Wei Charles W., Microprocessors for use in a device for predicting physiological values.
Bartkowiak, Miroslaw; Harper, Wesley S.; Kulcu, Eray; Lesho, Matthew J.; Tamada, Janet A., Microprocessors, devices and methods for use in analyte monitoring systems.
Carlisle Daniel Alan (Santa Barbara CA) Waybright Richard S. (Lompoc CA) Guillen Blanca (Goleta CA), Molded silicone foam implant and method for making.
Sasaki Darryl Y. ; Brinker C. Jeffrey ; Ashley Carol S. ; Daitch Charles E. ; Shea Kenneth J. ; Rush Daniel J., Molecular receptors in metal oxide sol-gel materials prepared via molecular imprinting.
Yan Mingdi (Eugene OR) Keana John F. W. (Eugene OR) Wybourne Martin N. (Eugene OR) Sevrain Christophe J. P. (Ridgefield WA), Molecularly imprinted materials, method for their preparation and devices employing such materials.
Markowitz Michael A. ; Schoen Paul E. ; Gaber Bruce P. ; Ratna Banahalli R. ; Kust Paul R. ; Turner David C. ; Clark Douglas S. ; Dordick Jonathan S., Molecularly-imprinted material made by template-directed synthesis.
Berner Bret ; Chiang Chia-Ming ; Garrison Michael D. ; Jona Janan ; Potts Russell O. ; Tamada Janet A. ; Tierney Michael J., Monitoring of physiological analytes.
Wohlstadter Jacob N. ; Wilbur James ; Sigal George ; Martin Mark ; Guo Liang-Hong ; Fischer Alan ; LeLand Jon, Multi-array, multi-specific electrochemiluminescence testing.
Domb Abraham J.,ILX ; Gref Ruxandra,FRX ; Minamitake Yoshiharu,JPX ; Peracchia Maria Teresa,ITX ; Langer Robert S., Nanoparticles and microparticles of non-linear hydrophilic-hydrophobic multiblock copolymers.
Tarr Randall V. (Atlanta GA) Steffes Paul G. (Norcross GA), Non-invasive blood glucose measurement system and method using stimulated Raman spectroscopy.
Sodickson Lester (P.O. Box 148 Waban MA) Block Myron J. (P.O. Box 148 North Salem NH 03073), Non-spectrophotometric measurement of analyte concentrations and optical properties of objects.
Janata Jiri A. (Salt Lake City UT) Janata Jarmila (Salt Lake City UT), Novel protein-immobilizing hydrophobic polymeric membrane, process for producing same and apparatus employing same.
Yoon Gil-won,KRX ; Lee Sang-min,KRX ; Kim Hong-sig,KRX ; Kim Won-ky,KRX, Optical diagnosis point detector for noninvasive diagnosis of blood constituents and noninvasive diagnostic device.
Oka Tohru,JPX ; Takakura Makoto,JPX, Physical information monitor system having means for determining reference range for abnormality determination, based.
Schaffar Bernhard (Graz ATX) Kontschieder Heinz (Graz ATX) Dolezal Andreas (Graz ATX) Ritter Christoph (Graz ATX), Planar sensor for determining a chemical parameter of a sample.
Clark ; Jr. Leland (Cincinnati OH), Polarographic method for measuring both analyte and oxygen with the same detecting electrode of an electroenzymatic sens.
Betts Ronald E. (La Jolla CA) Savage Douglas R. (Del Mar CA) Leader Matthew J. (Laguna Niguel CA), Portable analyte measuring system for multiple fluid samples.
Neuenfeldt Steven (Vernon Hills IL) Brauker James (Lake Ville IL) Clarke Robert (Libertyville IL), Ported tissue implant systems and methods of using same.
Swette Larry L. ; Griffith Arthur E. ; LaConti Anthony B., Potential and diffusion controlled solid electrolyte sensor for continuous measurement of very low levels of transdermal.
Fidler John C. (DeKalb) Bobis James P. (Downers Grove) Penrose William R. (Naperville) Stetter Joseph R. (Naperville IL), Potentiostatic apparatus and methods.
Say James ; Tomasco Michael F. ; Heller Adam ; Gal Yoram,ILX ; Aria Behrad ; Heller Ephraim ; Plante Phillip John ; Vreeke Mark S., Process for producing an electrochemical biosensor.
Carr Daniel J. (Harleysville PA) Scally Charles R. (Warminister PA) Carney Michael D. (Havertown PA) Kern Scott L. (Perkasie PA) Satko Thomas A. (Ivyland PA) Zecca James W. (Telford PA), Programmable electronic display for a chart recorder.
Phillips Roger (Palo Alto CA) McGarraugh Geoffery (Scotts Valley CA) Jurik Franklin A. (San Mateo CA) Underwood Raymond D. (Red Bluff CA), Reagent test strip and apparatus for determination of blood glucose.
Shin, John J.; Holtzclaw, Kris R.; Dangui, Nandita D.; Kanderian, Jr., Sami; Mastrototaro, John J.; Hong, Peter I., Real time self-adjusting calibration algorithm.
Schulman Joseph H. (Santa Clarita CA) Mann Alfred E. (Beverly Hills CA), Replaceable catheter system for physiological sensors, tissue stimulating electrodes and/or implantable fluid delivery s.
Reghabi,Bahar; Shah,Rajiv; Jin,Eunjoo; Gottlieb,Rebecca; Miller,Michael E.; Van Antwerp,Nannette M.; Enegren,Bradley J.; Van Antwerp,William P.; Mastrototaro,John J., Reusable analyte sensor site and method of using the same.
Karinka, Shridhara Alva; Moser, Isabella; Jobst, Gerhard; Tietjen, Uwe; Petrou, Panagiota S.; Herberth, Uwe; Urban, Gerald, Sensor having electrode for determining the rate of flow of a fluid.
Brauker, James H.; Carr-Brendel, Victoria; Goode, Paul V.; Kamath, Apurv U.; Thrower, James P.; Xavier, Ben, Signal processing for continuous analyte sensor.
Berner Bret ; Dunn Timothy C. ; Farinas Kathleen C. ; Garrison Michael D. ; Kurnik Ronald T. ; Lesho Matthew J. ; Potts Russell O. ; Tamada Janet A. ; Tierney Michael J., Signal processing for measurement of physiological analysis.
Benjamin J. Feldman ; Adam Heller ; Ephraim Heller ; Fei Mao ; Joseph A. Vivolo ; Jeffery V. Funderburk ; Fredric C. Colman ; Rajesh Krishnan, Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator.
Cordero Rafael M. ; Devlin Philip H. ; Chamoun Nassib G. ; Shambroom John R. ; Merrick Edwin B. ; Melo Joao, Smart electrophysiological sensor system with automatic authentication and validation and an interface for a smart electrophysiological sensor system.
Sheridan, Margaret M.; Bries, James L.; Malmer, Jeffrey D.; Sherman, Audrey A.; Kinning, David J., Stretch releasing pressure sensitive adhesive tape and articles.
Hill Hugh Allen Oliver (Oxford GB3) Higgins Irving John (Bedford GB3) McCann James Michael (Oxford GB3) Davis Graham (Plainsborough NJ), Strip electrode with screen printing.
Keith,Steven; Parker,Robert S.; Harvey,Noel G.; Pettis,Ronald J.; DeNuzzio,John D.; Vonk,Glenn, System and method for initiating and maintaining continuous, long-term control of a concentration of a substance in a patient using a feedback or model-based controller coupled to a single-needle or .
Goode, Jr., Paul V.; Brauker, James H.; Kamath, Apurv U.; Thrower, James Patrick; Carr-Brendel, Victoria, Systems and methods for replacing signal artifacts in a glucose sensor data stream.
Goode, Jr., Paul V.; Brauker, James H.; Kamath, Apurv U.; Thrower, James Patrick; Carr-Brendel, Victoria, Systems and methods for replacing signal artifacts in a glucose sensor data stream.
Mann, Alfred E.; Purvis, Richard E.; Mastrototaro, John J.; Causey, James D.; Henke, James; Hong, Peter; Livingston, John H.; Hague, Clifford W.; Hite, Brad T., Telemetered characteristic monitor system and method of using the same.
Bayerl Thomas,DEX ; Decher Gero,DEX ; Braunschweig Thomas,DEX, Template induced patterning of surfaces and their reversible stabilization using phase transitions of the patterned material.
Grill ; Jr. Warren M. (Cleveland Hts. OH) Creasey Graham H. (Cleveland Hts. OH) Ksienski David A. (Hermosa Beach CA) Veraart Claude S. (Brussels OH BEX) Mortimer J. Thomas (Chagrin Falls OH), Thin film implantable electrode and method of manufacture.
Brauker James H. (Harvard IL) Hill Ronald S. (Grayslake IL) Martinson Laura A. (Lake Villa IL) Boggs Daniel R. (Libertyville IL) Johnson Robert C. (Bartlett IL), Tissue implant systems and methods for sustaining viable high cell densities within a host.
Brauker James H. (Harvard IL) Hill Ronald S. (Grayslake IL) Martinson Laura A. (Lake Villa IL) Boggs Daniel R. (Libertyville IL) Johnson Robert C. (Bartlett IL), Tissue inplant systems and methods for sustaining viable high cell densities within a host.
Cheney ; II Paul S. (Beverly Hills CA) Mastrototaro John J. (Los Angeles CA) Schnabel Nannette M. (Valencia CA) Lord Peter C. (Valencia CA) Van Antwerp William P. (Los Angeles CA) Clark Raymond D. (V, Transcutaneous sensor insertion set.
Lord Peter C. (Santa Clarita CA) Van Antwerp William P. (Brentwood CA) Mastrototaro John J. (Los Angeles CA) Cheney ; II Paul S. (Beverly Hills CA) Schnabel Nannette M. (Valencia CA), Transcutaneous sensor insertion set.
Linda Hockersmith ; Thomas B. Blank ; Stephen L. Monfre ; Timothy L. Ruchti, Use of targeted glycemic profiles in the calibration of a noninvasive blood glucose monitor.
Band David M. (88 Ditton Road ; Surbiton Surrey GBX) Penman David G. (No. 1 Brief Street ; Myatts Field London UT GBX) Kratochvil Jiri (3551 S. Canyon Way Salt Lake City UT), pH electrode.
Levine, Andy H.; Kanzler, Christoph Matthias; Miranda, Daniel Leo; Mooney, Joseph; Lam, Huy; Osborne, John; Karabas, Mustafa; Dunne, Alan; Niemi, James; Matthews, Benjamin; Ingber, Donald E.; Henry, Olivier; Indic, Premananda Pai, Systems and methods for monitoring, managing, and treating asthma and anaphylaxis.
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