Differential neurostimulation therapy driven by physiological therapy
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61N-001/00
A61N-001/36
A61M-005/142
A61N-001/05
출원번호
US-0784569
(2013-03-04)
등록번호
US-8934980
(2015-01-13)
발명자
/ 주소
Pless, Benjamin D.
Tcheng, Thomas K.
출원인 / 주소
NeuroPace, Inc.
대리인 / 주소
Arent Fox LLP
인용정보
피인용 횟수 :
0인용 특허 :
99
초록▼
An implantable neurostimulator system adapted to provide therapy for various neurological disorders is capable of varying therapy delivery strategies based on the context, physiological or otherwise, into which the therapy is to be delivered. Responsive and scheduled therapies can be varied dependin
An implantable neurostimulator system adapted to provide therapy for various neurological disorders is capable of varying therapy delivery strategies based on the context, physiological or otherwise, into which the therapy is to be delivered. Responsive and scheduled therapies can be varied depending on various sensor measurements, calculations, inferences, and device states (including elapsed times and times of day) to deliver an appropriate course of therapy under the circumstances.
대표청구항▼
1. An implantable medical device system comprising: an implantable medical device configured to acquire EEG signals from a patient, to detect a neurological event of interest based on one or more EEG parameters derived from the EEG signals, and to store in a memory, a representation of the EEG signa
1. An implantable medical device system comprising: an implantable medical device configured to acquire EEG signals from a patient, to detect a neurological event of interest based on one or more EEG parameters derived from the EEG signals, and to store in a memory, a representation of the EEG signals, together with the one or more EEG parameters;an external component provided with a software operating program and associated hardware and configured to process, store, playback and display on a display of the external component the representation of the EEG signals and the one or more EEG parameters stored in the memory of the implantable medical device; anda communication link configured to establish communication between a communications subsystem of the implantable medical device and the external component to enable the external component to process, store, playback and display on the display of the external component the representation of the EEG signals acquired and stored in the implantable medical device;wherein the software operating program and associated hardware of the external component is configured to process the EEG signals received from the implantable medical device in order to simulate the detection of the neurological event. 2. The implantable medical device system of claim 1 wherein the communication link is a wireless link configured using a short distance first link between the implantable medical device and a transceiver, and the transceiver is configured to relay communications between the implantable medical device and the external component. 3. The implantable medical device system of claim 1 wherein the communication link is a wireless link configured using a long distance first link between the implantable medical device and a transceiver, and the transceiver is configured to relay information between the implantable medical device and the external component. 4. The implantable medical device system of claim 1 wherein the implantable medical device is further configured to acquire information corresponding to signal activity sensed by at least one sensor in operable communication with the implantable medical device, and the software operating program and associated hardware of the external component is further configured to process the signal activity received from the implantable medical device in order to simulate the detection and prediction of sensor signal activity representative of movement disorders based on a predetermined template developed for the patient. 5. The implantable medical device system of claim 1 wherein the implantable medical device is further configured with at least one analysis tool configured to derive the EEG parameters, and the software operating program and associated hardware of the external component is further configured to at least one of process, store, playback and display on the display of the external component the neurological event detected in the EEG signals based on the derived EEG parameters. 6. The implantable medical device system of claim 1 wherein the implantable medical device is further configured with operational parameters stored in the memory of the implantable medical device, and the software operating program and associated hardware of the external component is further configured to at least one of process, store, playback and display the operational parameters on the display of the external component. 7. The implantable medical device system of claim 1 wherein the display of EEG parameters on the external component may be directly associated with the display of the representation of the EEG signals. 8. The implantable medical device system of claim 1 wherein the display of EEG parameters on the display of the external component may be indirectly associated with the display of the representation of the EEG signals. 9. The implantable medical device system of claim 1, the implantable medical device further configured with: a therapy subsystem provided with at least one of a therapeutic stimulator, a sensory stimulator, and a diagnostic stimulator, wherein each of the therapeutic stimulator, the sensory stimulator and the diagnostic stimulator is configured to deliver a form of neuromodulation to the neural tissue of a patient, the form of neuromodulation characterized by one or more therapy parameters;a memory subsystem including the memory in which the representation of the EEG signals and the EEG parameters are stored and other memory in which the therapy parameters, if any, are stored, andthe software operating program and associated hardware of the external component is further configured to at least one of process, store, playback and display on the display of the external component at least the representation of the EEG signals, the neurological event detected in the EEG signals based on the derived EEG parameters, if any, and the form of neuromodulation delivered, if any, based on the therapy parameters. 10. The implantable medical device system of claim 9, further comprising an adaptive subsystem configured to do one of the following based on the EEG parameters, if any: correlate or decorrelate the form of neuromodulation therapy based on one or more of the derived parameters. 11. The implantable medical device system of claim 1, wherein the external component is further configured to process the EEG parameters to derive a characteristic of the EEG signals. 12. The implantable medical device system of claim 11, wherein the EEG parameter comprises half-wave measurements and the derived characteristic is frequency content information. 13. The implantable medical device system of claim 11, wherein the EEG parameter comprises line length measurements and the derived characteristic is signal variation information. 14. The implantable medical device system of claim 11, wherein the EEG parameter comprises area measurements and the derived characteristic is energy information. 15. A method of communicating information between an implantable neurostimulator and at least one external component configured to process, store, playback and display on a display of the external component a representation of EEG signals acquired and stored in the implantable neurostimulator, comprising: acquiring signal activity from the patient's brain from at least one sensor, the at least one sensor in operable communication with the implantable neurostimulator;processing the signal activity with the implantable neurostimulator to provide a digital representation of the signal activity, and to detect a neurological event of interest based on one or more signal parameters derived from the signal activity;storing the digital representation of the signal activity, together with the one or more signal parameters, in an area of memory in a memory subsystem of the implantable neurostimulator;establishing a communication link between the implantable neurostimulator and the external component and communicating through the communication link the digital representation of the signal activity from the area of memory to the external component; andwith a software operating program and associated hardware of the external component, processing and displaying on a display of the external component the representation of the signal activity and the signal parameters received from the implantable medical device, and processing the signal activity in order to simulate the detection of the neurological event.
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이 특허에 인용된 특허 (99)
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