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Primate pluripotent stem cell expansion without feeder cells and in the presence of FGF and matrigel or Engelbreth-Holm-Swarm tumor cell preparation 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C12N-005/02
  • C12N-015/10
  • C12N-005/0735
  • C12N-005/0793
  • C12N-005/079
  • C12N-005/074
  • C12N-005/00
  • C12N-005/071
  • C12N-011/04
  • C12N-005/073
  • C12N-005/09
  • C12N-005/0775
출원번호 US-0710078 (2010-02-22)
등록번호 US-8951800 (2015-02-10)
발명자 / 주소
  • Mandalam, Ramkumar
  • Xu, Chunhui
  • Gold, Joseph D.
  • Carpenter, Melissa K.
출원인 / 주소
  • Asterias Biotherapeutics, Inc.
대리인 / 주소
    Mittler, E. Stewart
인용정보 피인용 횟수 : 0  인용 특허 : 59

초록 ▼

This disclosure provides an improved system for culturing human pluripotent stem cells. Traditionally, pluripotent stem cells are cultured on a layer of feeder cells (such as mouse embryonic fibroblasts) to prevent them from differentiating. In the system described here, the role of feeder cells is

대표청구항 ▼

1. A system for expanding primate pluripotent stem cells in vitro without feeder cells comprising a nutrient media comprising primate pluripotent stem cells, a fibroblast growth factor and a soluble preparation from Engelbreth-Holm-Swarm tumor cells. 2. The system of claim 1, wherein the nutrient me

이 특허에 인용된 특허 (59)

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