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Bupivacaine formulation in a polyorthoester carrier

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61F-002/00
  • A01N-043/40
  • A61K-031/445
  • A61L-031/16
출원번호 US-0426005 (2009-04-17)
등록번호 US-8956642 (2015-02-17)
발명자 / 주소
  • Hobot, Christopher M.
  • Benz, Michael E.
  • Hildebrand, Keith R.
  • Pudil, Bryant J.
출원인 / 주소
  • Medtronic, Inc.
대리인 / 주소
    Sorell Lenna & Schmidt LLP
인용정보 피인용 횟수 : 0  인용 특허 : 89

초록

Effective treatments of pain, such as chronic pelvic pain, for extended periods of time are provided. The treatments include the administration of one or more drug depots intraspinally wherein the drug depots include an effective amount of bupivacaine formulated within a polyorthoester. By administr

대표청구항

1. An implantable drug depot useful for reducing, or treating pain in a patient in need of such treatment, the drug depot comprising a polyorthoester and bupivacaine, the drug depot adapted to be administered intraspinally in the patient to reduce, or treat pain, wherein the drug depot is capable of

이 특허에 인용된 특허 (89)

  1. Himmelstein Kenneth J. (Lawrence KS) Higuchi Takeru (Lawrence KS), Acid anhydrides as rate controlling agent for the erosion of polymers which latter polymers have beneficial substances d.
  2. Daniels Alma U. (Salt Lake City UT) Heller Jorge (Woodside CA), Biodegradable composites for internal medical use.
  3. Sankaram, Mantripragada, Biodegradable compositions for the controlled release of encapsulated substances.
  4. Berde Charles B. (Brookline MA) Langer Robert S. (Newton MA), Biodegradable polymer matrices for sustained delivery of local anesthetic agents.
  5. Berde Charles B. ; Langer Robert S., Biodegradable polymer matrices for sustained delivery of local anesthetic agents.
  6. Kohn Joachim B. ; Bolikal Durgadas ; Brode George L. ; Ertel Sylvie I.,FRX ; Guan Shuiyun ; Kemnitzer John E., Biodegradable, anionic polymers derived from the amino acid L-tyrosine.
  7. Shih Chung ; Zentner Gaylen M. ; Sparer Randall V. ; Seward R. Lee, Bioerodible implants.
  8. Ng, Steven Y.; Heller, Jorge, Bioerodible poly (orthoesters) from dioxolane-based diketene acetals.
  9. Sparer, Randall V.; Pogany, Stefano A., Bioerodible poly(ortho ester) thermoplastic elastomer from diketene diacetal.
  10. Heller,Jorge; Ng,Steven Y., Bioerodible poly(ortho esters) from dioxane-based di(ketene acetals), and block copolymers containing them.
  11. Heller,Jorge; Ng,Steven Y., Bioerodible poly(ortho esters) from dioxane-based di(ketene acetals), and block copolymers containing them.
  12. Heller Jorge (Woodside CA) Ng Steve Y. W. (San Francisco CA), Bioerodible polymers for solid controlled release pharmaceutical compositions.
  13. Ng Steve Y. W. (San Francisco CA) Heller Jorge (Woodside CA), Bioerodible polymers useful for the controlled release of therapeutic agents.
  14. Ng Steve Y. W. (San Francisco CA) Heller Jorge (Woodside CA), Bioerodible polymers useful for the controlled release of therapeutic agents.
  15. Ng Steve Y. W. ; Heller Jorge, Bioerodible polymers, compositions and therapeutic method.
  16. Ng, Steven Y.; Heller, Jorge, Bioerodible polyorthoesters containing amine groups.
  17. Liu Lin-Shu ; Froix Michael ; Heller Jorge ; Ng Steven Y., Bioerodible porous compositions.
  18. Ng, Steven Y.; Heller, Jorge, Block copolymers based on poly(ortho esters) containing amine groups.
  19. Ng, Steven Y.; Heller, Jorge, Block copolymers based on poly(ortho esters) containing amine groups.
  20. Elsberry, Dennis D.; Christiansen, Chris; Morris, Mary M.; Hankner, Douglas Owen; Hamlen, Robert Cushing, Catheter for target specific drug delivery.
  21. Hassenbusch ; III Samuel J. ; Edeburn Patrick ; Trissel Lawrence A., Clonidine therapy enhancement.
  22. Pacetti,Stephen D., Coatings for drug delivery devices based on poly (orthoesters).
  23. Edward M. Gillis ; Felix Theeuwes, Composite drug delivery catheter.
  24. Schacht, Etienne Honor?, Composition of crosslinkable prepolymers for biodegradable implants.
  25. Tobinick,Edward Lewis, Cytokine antagonists for neurological and neuropsychiatric disorders.
  26. Thompson, David L., Drug delivery device.
  27. Caldwell Larry J. (Lawrence KS) Gardner Colin R. (Lawrence KS) Cargill Robyn C. (Lawrence KS), Drug delivery device which can be retained in the stomach for a controlled period of time.
  28. Caldwell Larry J. (Lawrence KS) Gardner Colin R. (Lawrence KS) Cargill Robyn C. (Lawrence KS), Drug delivery device which can be retained in the stomach for a controlled period of time.
  29. Caldwell Larry J. (Lawrence KS) Gardner Colin R. (Lawrence KS) Cargill Robyn C. (Lawrence KS) Higuchi Takeru (Lawrence KS), Drug delivery device which can be retained in the stomach for a controlled period of time.
  30. Choi ; Nam Sok ; Heller ; Jorge, Drug delivery devices manufactured from poly(orthoesters) and poly(orthocarbonates).
  31. Gruber Andres ; Murdande Sharad B. ; Kim Taehee ; Kim Sinil, Epidural administration of therapeutic compounds with sustained rate of release.
  32. Choi Nam S. (Seoul CA KRX) Heller Jorge (Palo Alto CA), Erodible agent releasing device comprising poly(orthoesters) and poly(orthocarbonates).
  33. Chasin Mark ; Sackler Richard ; Burch Ronald M. ; Goldenheim Paul ; Tigner Joseph, Formulations and methods for providing prolonged local anesthesia.
  34. Chasin, Mark; Goldenheim, Paul; Sackler, Richard; Tigner, Joseph; Burch, Ronald M, Formulations and methods for providing prolonged local anesthesia.
  35. Chasin, Mark; Sackler, Richard; Burch, Ronald M.; Goldenheim, Paul; Tigner, Joseph, Formulations and methods for providing prolonged local anesthesia.
  36. Goldenheim, Paul; Chasin, Mark; Sackler, Richard; Burch, Ronald M.; Tigner, Joseph, Formulations and methods for providing prolonged local anesthesia.
  37. Berde Charles B. ; Langer Robert S. ; Curley Joanne ; Castillo Jenny, High load formulations and methods for providing prolonged local anesthesia.
  38. Tipton Arthur J. ; Holl Richard J., High viscosity liquid controlled delivery system.
  39. John W. Gibson ; Stacey A. Sullivan ; John C. Middleton ; Arthur J. Tipton, High viscosity liquid controlled delivery system and medical or surgical device.
  40. Tipton Arthur J., High viscosity liquid controlled delivery system as a device.
  41. Ashton Paul ; Pearson Paul A., Implantable controlled release device to deliver drugs directly to an internal portion of the body.
  42. Rise Mark T. ; Baudino Michael D., Implantable techniques for infusing equal volumes of agents to spaced sites.
  43. Aebischer Patrick (Barrington RI) Goddard Moses (Tiverton RI) Moldauer John G. (Brooklyn NY) Mulhauser Paul J. (New York NY) Rathbun Anne M. (Providence RI) Sanberg Paul R. (Greenwich RI) Vasconcello, Implantable therapy systems and methods.
  44. Elsberry, Dennis D., Intraparenchymal infusion catheter system.
  45. Hori, Shuuji; Mototani, Masayoshi; Nojiri, Mikio; Endo, Takeshi, Lever-operated actuator drive unit and operating lever unit.
  46. Nelson Timothy S. ; Bergan Matthew A., Method and apparatus for administering analgesics, and method for making same device.
  47. Nelson Timothy S. ; Bergan Matthew A., Method and device for administering analgesics.
  48. Hildebrand, Keith Robert, Method for treating severe tinnitus.
  49. Heller Jorge (Woodside CA) Penhale Donald W. H. (Menlo Park CA) Ng Steve Y. (San Francisco CA), Method of preparing bioerodible polymers having pH sensitivity in the acid range and resulting product.
  50. Heller Jorge (Woodside CA) Penhale Donald W. H. (Menlo Park CA) Ng Steve Y. (San Francisco CA), Method of preparing bioerodible polymers having pH sensitivity in the acid range and resulting product.
  51. Newsome, Peter W.; Frisbee, A. Roger; Itov, Zinovy; Morgan, April J.; Noe, Robert A., Method of preparing di(ketene acetals).
  52. Wong, Erik H. F.; Ahmed, Saeeduddin; Marshall, Robert C.; McArthur, Robert; Taylor, Duncan P.; Birgerson, Lars; Cetera, Pasquale, Method of treating chronic pain.
  53. Erik H. F. Wong ; Saeeduddin Ahmed ; Robert C. Marshall ; Robert McArthur ; Duncan P. Taylor ; Lars Birgerson ; Pasquale Cetera, Method of treating or preventing chronic pain with a highly selective norepinephrine reuptake inhibitor.
  54. Elkhoury George F., Methods and devices for delivering opioid analgesics to wounds via a subdermal implant.
  55. Sackler, Richard S.; Goldenheim, Paul D.; Chasin, Mark; Burch, Ronald M.; Reder, Robert F.; Tigner, Joseph, Methods for providing safe local anesthesia.
  56. Tice Thomas R. (Helena AL) Lewis Danny H. (Gardendale AL), Microencapsulation process.
  57. Kohn Joachim (Brookline MA) Langer Robert S. (Somerville MA), Non-peptide polyamino acid bioerodible polymers.
  58. Zaffaroni Alejandro (Atherton CA), Novel drug delivery device.
  59. Choi Nam S. (Seoul CA KRX) Heller Jorge (Palo Alto CA), Novel orthoester polymers and orthocarbonate polymers.
  60. Zentner Gaylen M. (Lawrence KS) Himmelstein Kenneth J. (Irvine CA) Pogany Stefano A. (Lawrence KS) Ringeisen Cheryl (Olathe KS), Organic acids as catalysts for the erosion of polymers.
  61. Heller Jorge (Woodside CA) Ng Steve Y. W. (San Francisco CA) Penhale Donald W. H. (Menlo Park CA), Ortho and thio-ortho ester polymer.
  62. Heller Jorge ; Ng Steven Y., PEG-POE, PEG-POE-PEG, and POE-PEG-POE block copolymers.
  63. Ng, Steven Y.; Shen, Hui-Rong; Heller, Jorge, Pharmaceutical compositions using semi-solid delivery vehicle.
  64. Ng, Steven Y.; Shen, Hui-Rong; Heller, Jorge, Pharmaceutical compositions using semi-solid delivery vehicle.
  65. Hubbell, Jeffrey A.; Pathak, Chandrashekhar P.; Sawhney, Amarpreet S.; Desai, Neil P.; Hill, Jennifer L., Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers.
  66. Choi ; Nam Sok ; Heller ; Jorge, Poly(carbonates).
  67. Pogany Stefano A. (Lawrence KS) Zentner Gaylen M. (Lawrence KS), Poly(orthocarbonate acetal) bioerodible polymers.
  68. Heller Jorge (Woodside CA) Penhale Donald W. H. (Menlo Park CA) Ng Steve Y. (San Francisco CA), Polyacetal and polyketal hydrogels formed from acetals or ketals and polyols.
  69. Kroner Matthias (Eisenberg DEX) Hartmann Heinrich (Limburgerhof DEX) Baur Richard (Mutterstadt DEX) Schwendemann Volker (Neustadt DEX) Jaeger Hans-Ulrich (Neustadt DEX) Perner Johannes (Neustadt DEX), Polyacetals based on divinyl ethers, dihydroxy compounds and monohydroxy compounds.
  70. Coates Geoffrey W. ; Cheng Ming, Polycarbonates made using high activity catalysts.
  71. Musa,Osama M., Polymer compounds containing oxetane and maleimide functionality.
  72. Capozza Richard C. (Palo Alto CA), Polymeric orthoesters having arylene arrangement.
  73. Heller Jorge (Woodside CA) Ng Steve Y. W. (San Francisco CA) Penhale Donald W. H. (Menlo Park CA), Polymers containing acetal, carboxy-acetal, ortho ester and carboxyortho ester linkages.
  74. Heller Jorge (Woodside CA) Ng Steve Y. W. (San Francisco CA) Penhale Donald W. H. (Menlo Park CA), Polymers containing carboxy-ortho ester and ortho ester linkages.
  75. Heller Jorge (Woodside CA), Polymers containing pendant acid functionalities and labile backbone bonds.
  76. Heller Jorge (Woodside CA), Polymers containing pendant acid functionalities and labile backbone bonds.
  77. Heller Jorge (Palo Alto CA) Helwing Robert F. (Sunnyvale CA) Penhale Donald W. (Cupertino CA), Polymers of di- (and higher functionality) ketene acetals and polyols.
  78. Heller Jorge ; Ng Steven Y., Polymers with controlled physical state and bioerodibility.
  79. Ng Steven Y. (San Francisco CA) Penhale Donald W. (Cupertino CA) Heller Jorge (Woodside CA), Preparation of ketene acetals.
  80. Helwing Robert F. (San Jose CA), Preparation of ketene acetals by rearrangement of allyl and substituted allyl acetals.
  81. Sparer Randall V. (Lawrence KS) Zentner Gaylen (Lawrence KS), Process for the manufacture of bioerodible poly (orthoester)s and polyacetals.
  82. Goldenheim Paul ; Lacouture Peter ; Donigi-Gale Donna ; Chasin Mark ; Sackler Richard, Prolonged anesthesia in joints and body spaces.
  83. Goldenheim, Paul; Donigi-Gale, Donna; Sackler, Richard; Lacouture, Peter; Chasin, Mark, Prolonged anesthesia in joints and body spaces.
  84. Sackler Richard ; Goldenheim Paul ; Chasin Mark, Prolonged local anesthesia with colchicine.
  85. Berde Charles B. (Brookline MA) Langer Robert S. (Newton MA), Prolonged nerve blockade by the combination of local anesthetic and glucocorticoid.
  86. Ng, Steven Y.; Shen, Hui-Rong; Heller, Jorge, Semi-solid delivery vehicle and pharmaceutical compositions.
  87. Choi ; Nam S. ; Heller ; Jorge, Structured orthoester and orthocarbonate drug delivery devices.
  88. Drizen Alan,CAX ; Rothbart Peter,CAX ; Nath Gary M., Sustained release delivery system.
  89. Kohn Joachim B. (Highland Park NJ) Hooper Kimberly A. (Long Valley NJ), Synthesis of tyrosine derived diphenol monomers.
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