[특허]Method for applying flowable hydrogels to a cornea

Method for applying flowable hydrogels to a cornea 원문보기

IPC분류정보
국가/구분	United States(US) Patent 등록
국제특허분류(IPC7판)	A61B-018/18 A61F-002/00 A61K-009/00 A61K-009/06 A61K-047/34
출원번호	US-0884466 (2010-09-17)
등록번호	US-8961501 (2015-02-24)
발명자 / 주소	Jarrett, Peter El Hayek, Rami Bassett, Michael Biggins, James
출원인 / 주소	Incept, LLC
대리인 / 주소	Dardi & Herbert, PLLC
인용정보	피인용 횟수 : 0 인용 특허 : 232

초록 ▼

Materials and methods of treating an eye with a hydrogel formed on the eye. Embodiments are provided that include post-keratectomy bandages. A method of treating a patient by application of a hydrogel bandage to a cornea by providing a first hydrogel precursor in a dry form immobilized in a first deposit at a first location in a well, providing a second hydrogel precursor in a dry form immobilized in a second deposit at a second location in the well, mixing the deposits together to form a mixture, and transferring at least some of the mixture to the cornea, with the mixture forming a covalently crosslinked hydrogel on the cornea.

대표청구항 ▼

1. A method of treating a patient by application of a hydrogel bandage to a cornea comprising: providing a first hydrogel precursor in a dry form immobilized in a first deposit at a first location in a well,providing a second hydrogel precursor in a dry form immobilized in a second deposit at a second location in the well,adding less than 1000 μl of aqueous solution to one or more of the deposits to thereby dissolve the first and/or the second hydrogel precursor;mixing the deposits together to form a mixture comprising the first hydrogel precursor and the second hydrogel precursor,introducing a delivery surface to the mixture and recovering a volume between 1 and 100 μl of the mixturetransferring at between 1 and 100 μl of the volume from the delivery surface to the cornea,with the mixture forming a covalently crosslinked hydrogel on the cornea,wherein said immobilization prevents the hydrogel precursor from moving from the location until such time as it is dissolved in the aqueous solution and wherein said immobilization prevents the first hydrogel precursor in the dry form and the second hydrogel precursor in the dry form from mixing together before being dissolved. 2. The method of claim 1 wherein the first precursor comprises a first functional group and the second precursor comprises a second functional group, with the first functional group and the second functional group reacting with each other to form covalent bonds to thereby form the covalently crosslinked hydrogel. 3. The method of claim 1 wherein the first and/or second deposit further comprises a visualization agent that, before application to the eye, is visible without a machine aid to a user applying the solution. 4. The method of claim 1 wherein the hydrogel is fully degraded on the cornea within less than 10 days. 5. The method of claim 1 wherein the mixture has a pH of between 6 and 8. 6. The method of claim 2 wherein the first precursor comprises polyethylene glycol and the first functional group or the second functional group comprises a succinimidyl ester. 7. The method of claim 2 with the mixture further comprising a drug subsequently released from the hydrogel. 8. The method of claim 1 wherein the covalently crosslinked hydrogel has a solids content of between 3% and 15% w/w. 9. The method of claim 1 wherein the mixture further comprises a visualization agent that, before application to the eye, is visible without a machine aid to a user applying the mixture. 10. The method of claim 1 wherein the mixture further comprises a drug subsequently released from the covalently crosslinked hydrogel. 11. The method of claim 1 wherein the deposits are mixed using an applicator comprises a first and second end, with a mixing rod forming the first end and the delivery surface being on the second end.

이 특허에 인용된 특허 (232)

Evan C. Unger, Acoustically active drug delivery systems.
상세보기
Zalipsky Shmuel (Edison NJ), Active carbonates of polyalkylene oxides for modification of polypeptides.
상세보기
Barrows Thomas H. (Cottage Grove MN) Lewis Terry W. (Woodbury MN) Truong Myhanh T. (Blaine MN), Adhesive sealant composition.
상세보기
Kupiecki David ; Teoh Clifford ; Doan Hong ; Gia Son M. ; Engelson Erik T. ; Chee Uriel Hiram ; Bashiri Mehran ; Eder Joseph C., Aneurysm closure device assembly.
상세보기
Chandrashenkhar P. Pathak ; Mark A. Moore ; Richard E. Phillips, Anticalcification treatments for fixed biomaterials.
상세보기
Pathak Chandrashekhar P. ; Sawhney Amarpreet S. ; Hubbell Jeffrey A. ; Herman Stephen J. ; Roth Laurence A. ; Campbell Patrick K. ; Berrigan Kevin M. ; Jarrett Peter K. ; Coury Arthur J., Apparatus and methods for intraluminal photothermoforming.
상세보기
Polson Alan M. (Fort Collins CO) Swanbom Deryl D. (Fort Collins CO) Dunn Richard L. (Fort Collins CO) Cox Charles P. (Fort Collins CO) Norton Richard L. (Fort Collins CO) Lowe Bryan K. (Fort Collins , Apparatus for forming a biodegradable implant precursor.
상세보기
Pathak Chandrashekhar P. (Waltham MA) Sawhney Amarpreet S. (Newton MA) Hubbell Jeffrey A. (Concord MA) Herman Stephen J. (Andover MA) Roth Laurence A. (Windham NH) Campbell Patrick K. (Georgetown MA), Apparatus for intraluminal photothermoforming.
상세보기
Ryan, Timothy J.; Evans, Michael A.; Lenker, Jay A.; Freislinger, Kirsten; Kim, Steven W.; Will, Allan R., Bifurcated intraluminal prostheses construction and methods.
상세보기
Slaikeu, Paul C.; Wallace, Michael P.; Eder, Joseph C.; Barry, James J.; Abrams, Robert M., Bioactive aneurysm closure device assembly and kit.
상세보기
Rhee Woonza M. ; Rao Prema R. ; Chu George H. ; DeLustro Frank A. ; Harner Carol F. H. ; Sakai Naomi ; Schroeder Jacqueline A., Biocompatible adhesive compositions.
상세보기
Rhee Woonza M. ; Rao Prema R. ; Chu George H. ; DeLustro Frank A. ; Harner Carol F. H. ; Sakai Naomi ; Schroeder Jacqueline A., Biocompatible adhesive compositions.
상세보기
Guire Patrick E. (Eden Prairie MN), Biocompatible coating for solid surfaces.
상세보기
Pathak, Chandrashekhar P.; Sawhney, Amarpreet S.; Edelman, Peter G., Biocompatible crosslinked polymers.
상세보기
Pathak,Chandrashekhar P.; Sawhney,Amarpreet S.; Edelman,Peter G., Biocompatible crosslinked polymers.
상세보기
Hubbell Jeffrey A. (Austin TX) Sawhney Amarpreet S. (Austin TX), Biocompatible microcapsules.
상세보기
Hubbell Jeffrey A. ; Sawhney Amarpreet S., Biocompatible microcapsules.
상세보기
Feijen Jan (Oude Grensweg NLX), Biodegradable hydrogel matrices for the controlled release of pharmacologically active agents.
상세보기
Dunn Richard L. (451 Boardwalk Dr. RLD ; Apt. 501 Fort Collins CO 80526) English James P. (2500 Melinda Cir. Birmingham AL 35214) Cowsar Donald R. (4657 Round Forest Dr. Birmingham AL 35213) Vanderbi, Biodegradable in-situ forming implants and methods of producing the same.
상세보기
Dunn Richard L. (Fort Collins CO) English James P. (Birmingham AL) Cowsar Donald R. (Birmingham AL) Vanderbilt David D. (Birmingham AL), Biodegradable in-situ forming implants and methods of producing the same.
상세보기
Gref Ruxandra (Nancy FRX) Minamitake Yoshiharu (Brookline MA) Langer Robert S. (Newton MA), Biodegradable injectable particles for imaging.
상세보기
Hubbell Jeffrey A.,CHX ; Kieras Mark T. ; Ron Eyal S. ; Rowe Stephen C., Biodegradable macromers for the controlled release of biologically active substances.
상세보기
DeLuca Patrick P. (Lexington KY) Rypacek Frantisek (Leckova CSX), Biodegradable microspheres as a carrier for macromolecules.
상세보기
Berde Charles B. (Brookline MA) Langer Robert S. (Newton MA), Biodegradable polymer matrices for sustained delivery of local anesthetic agents.
상세보기
Cohn Daniel (Jerusalem ILX) Younes Hani (Ara-Meshulush ILX) Uretzky Gideon (Jerusalem ILX), Biodegradable polymeric materials based on polyether glycols, processes for the preparation thereof and surgical article.
상세보기
Poff, Bradley C.; Herman, Stephen J.; Pichon, Dean M.; Sawhney, Amarpreet S., Biodegradable tissue retractor.
상세보기
Rhee Woonza (Palo Alto CA) Wallace Donald G. (Menlo Park CA) Michaels Alan S. (Boston MA) Burns ; Jr. Ramon A. (Fremont CA) Fries Louis (Los Altos CA) DeLustro Frank (Belmont CA) Bentz Hanne (Newark , Biologically inert, biocompatible-polymer conjugates.
상세보기
Pathak Chandrashekhar P. ; Moore Mark A. ; Philips ; Jr. Richard E., Blocked functional reagants for cross-linking biological tissues.
상세보기
Dean Thomas R. ; Desantis ; Jr. Louis ; York Billie M., Brinzolamide and brimonidine for treating glaucoma.
상세보기
Dean Thomas R. ; Desantis ; Jr. Louis ; York Billie M., Brinzolamide and brimonidine for treating ocular conditions.
상세보기
Karakelle,Mutlu; Brunstedt,Michael R., Carrageenan viscoelastics for ocular surgery.
상세보기
Rhee Woonza M. (Palo Alto CA) Rao Prema R. (Los Gatos CA) Chu George H. (Cupertino CA) DeLustro Frank A. (Belmont CA), Clear, chemically modified collagen-synthetic polymer conjugates for ophthalmic applications.
상세보기
Hubbell, Jeffrey A.; Pathak, Chandrashekhar P.; Sawhney, Amarpreet S.; Desai, Neil P.; Hill, Jennifer L.; Hossainy, Syed F. A., Coating substrates by polymerizing macromers having free radical-polymerizable substituents.
상세보기
Rhee Woonza (Palo Alto CA) Wallace Donald G. (Menlo Park CA) Michaels Alan S. (Boston MA) Burns ; Jr. Ramon A. (Fremont CA) Fries Louis (Los Altos CA) DeLustro Frank (Belmont CA) Bentz Hanne (Newark , Collagen-polymer conjugates.
상세보기
Rhee Woonza (Palo Alto CA) Wallace Donald G. (Menlo Park CA) Michaels Alan S. (Boston MA) Burns ; Jr. Ramon A. (Fremont CA) Fries Louis (Los Altos CA) DeLustro Frank (Belmont CA) Bentz Hanne (Newark , Collagen-polymer conjugates.
상세보기
Rhee Woonza (Palo Alto CA) Wallace Donald G. (Menlo Park CA) Michaels Alan S. (Boston MA) Burns ; Jr. Ramon A. (Fremont CA) Fries Louis (Los Altos CA) DeLustro Frank (Belmont CA) Bentz Hanne (Newark , Collagen-polymer conjugates containing an ether linkage.
상세보기
Sierra David H., Collagen-polymer matrices with differential biodegradability.
상세보기
Sierra David H., Collagen-polymer matrices with differential biodegradability.
상세보기
Sawhney,Amarpreet S.; Lyman,Michelle D.; Jarrett,Peter K.; Rudowsky,Ronald S., Compliant tissue sealants.
상세보기
Sawhney, Amarpreet S., Composite hydrogel drug delivery systems.
상세보기
Rhee, Woonza M.; DeLustro, Frank A.; Berg, Richard A., Composition for administration of a biologically active compound.
상세보기
Olof Mikael Trollsas ; Donald G. Wallace ; Frank A. DeLustro, Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use.
상세보기
Donald G. Wallace ; George H. Chu ; Jacqueline Anne Schroeder, Compositions and systems for forming high strength medical sealants, and associated methods of preparation and use.
상세보기
De Groot, Jacqueline Hermina; Hodd, Kenneth Albert; Haitjema, Hendrik Jan, Compositions capable of forming hydrogels in the eye.
상세보기
Hubbell Jeffrey A. ; Sawhney Amarpreet S., Compositions for coating microcapsules and other surfaces.
상세보기
Chang Nienyuan J. (Irvine CA) Himmelstein Kenneth J. (Omaha NE), Compositions for controlled delivery of pharmaceutical compounds.
상세보기
Greff Richard J. ; Jones Michael L. ; Evans Scott, Compositions for use in embolizing blood vessels.
상세보기
Gregory M Cruise ; Olexander Hnojewyj, Compositions, systems, and methods for arresting or controlling bleeding or fluid leakage in body tissue.
상세보기
Gregory M Cruise ; Olexander Hnojewyj, Compositions, systems, and methods for creating in situ, chemically cross-linked, mechanical barriers.
상세보기
Hubbell, Jeffrey A.; Elbert, Donald; Schoenmakers, Ronald, Conjugate addition reactions for the controlled delivery of pharmaceutically active compounds.
상세보기
Benjamin William J., Conjunctival inserts for topical delivery of medication or lubrication.
상세보기
Rhee, Woonza M.; DeLustro, Frank A.; Berg, Richard A., Cross-linked polymer compositions and methods for their use.
상세보기
Pathak C. P. ; Moore Mark A., Cross-linking tissue with a compound having a C.sub.8 to C.sub.40 aliphatic chain.
상세보기
Rhee, Woonza M., Crosslinkable biomaterial compositions containing hydrophobic and hydrophilic crosslinking agents.
상세보기
Chudzik Stephen J. ; Anderson Aron B., Crosslinkable macromers bearing initiator groups.
상세보기
Pathak,Chandrashekhar P., Crosslinked albumin hydrogels.
상세보기
Berg Richard A. ; Rosenblatt Joel S. ; Rhee Woonza M., Crosslinked collagen compositions for in situ administration.
상세보기
Rhee Woonza M. ; DeLustro Frank A. ; Berg Richard A., Crosslinked polymer compositions and methods for their use.
상세보기
Rhee Woonza M. ; DeLustro Frank A. ; Berg Richard A., Crosslinked polymer compositions and methods for their use.
상세보기
Pathak, Chandrashekhar P., Crosslinking agents and methods of use.
상세보기
Lenker, Jay A.; Cox, Brian J.; Evans, Michael A.; Weinberg, Steven, Cuffed endoluminal prosthesis.
상세보기
Hughes Howard C. (Cornwall PA) Kissinger Jacob T. (Mechanicsburg PA), Cuffed tubular organic prostheses.
상세보기
Hirt, Thomas; Holland, Troy; Francis, Vimala; Chaouk, Hassan, Degradable poly(vinyl alcohol) hydrogels.
상세보기
Sawhney, Amarpreet S.; Edelman, Peter G., Dehydrated hydrogel precursor-based, tissue adherent compositions and methods of use.
상세보기
Hoi S. (La Jolla CA), Detachable balloon catheter.
상세보기
Abrams Robert M., Detachable covering for an implantable medical device.
상세보기
John Kucharczyk ; Richard Latchaw, Device and method for the endovascular treatment of aneurysms.
상세보기
Parel Jean-Marie ; Behar Francine,FRX, Device for the intraocular transfer of active products by iontophoresis.
상세보기
Py,Daniel; Assion,Norbert M.; Chan,Julian V., Dispenser with sealed chamber, one-way valve and needle penetrable and laser resealable stopper.
상세보기
Clyde Lewis Schultz ; Janet M. Mint, Drug delivery system for antiglaucomatous medication.
상세보기
Melanson, David A.; Lyman, Michelle D.; Edelman, Peter G.; Sawhney, Amarpreet S., Dual component medicinal polymer delivery system and methods of use.
상세보기
McGurk Erin (Palo Alto CA) Dieck Ronald (Palo Alto CA) Tremulis William S. (Redwood City CA), Embolic elements and methods and apparatus for their delivery.
상세보기
Li, Shu-Tung; Lin, Horng-Ban; Yuen, Debbie, Embolization device.
상세보기
Ding Shulin ; Olejnik Orest ; Reis Brenda L., Emulsion eye drop for alleviation of dry eye related symptoms in dry eye patients and/or contact lens wearers.
상세보기
Cox Brian ; Evans Michael A. ; Will Allan ; Lenker Jay A. ; Kim Steven W. ; Freislinger Kirsten, Endoluminal prostheses and therapies for highly variable body lumens.
상세보기
Howard J. Leonhardt ; Syde A. Taheri ; Trevor Greenan, Endoluminal prosthesis.
상세보기
Greenberg, Roy K., Endovascular device having a stent.
상세보기
Rhodes Valentine J. (608 Winding River Rd. Bricktown NJ 08723), Endovascular prosthesis with improved sealing means for aneurysmal arterial disease and method of use.
상세보기
Marotta Thomas R.,CAX ; Shukov George A. ; Ricci Donald R.,CAX ; Penn Ian M.,CAX, Endovascular prothesis with expandable leaf portion.
상세보기
Thompson Richard J. ; Laptewicz ; Jr. Joseph E. ; Thompson Paul J., Esophageal stent.
상세보기
Azizi, Gholam-Reza Zadno, Exchange method for emboli containment.
상세보기
Jones, Donald K.; Mitelberg, Vladimir, Expandable stent and delivery system.
상세보기
Hubbell Jeffrey A. (Austin TX) Pathak Chandrashekhar P. (Waltham MA) Sawhney Amarpreet S. (Newton MA) Desai Neil P. (Los Angeles CA) Hill-West Jennifer L. (Austin TX) Hossainy Syed F. A. (Austin TX), Gels for encapsulation of biological materials.
상세보기
Hubbell Jeffrey A. (Concord MA) Pathak Chandrashekhar P. (Austin TX) Sawhney Amarpreet S. (Newton MA) Desai Neil P. (Los Angeles CA) Hossainy Syed F. A. (Austin TX), Gels for encapsulation of biological materials.
상세보기
Hubbell Jeffrey A. ; Pathak Chandrashekhar P. ; Sawhney Amarpreet S. ; Desai Neil P. ; Hill Jennifer L. ; Hossainy Syed F. A., Gels for encapsulation of biological materials.
상세보기
Hubbell Jeffrey A. ; Pathak Chandrashekhar P. ; Sawhney Amarpreet S. ; Desai Neil P. ; Hill Jennifer L. ; Hossainy Syed F. A., Gels for encapsulation of biological materials.
상세보기
Hubbell Jeffrey A. ; Pathak Chandrashekhar P. ; Sawhney Amarpreet S. ; Desai Neil P. ; Hill Jennifer L. ; Hossainy Syed F. A., Gels for encapsulation of biological materials.
상세보기
Hubbell Jeffrey A. ; Pathak Chandrashekhar P. ; Sawhney Amarpreet S. ; Desai Neil P. ; Hossainy Syed F. A., Gels for encapsulation of biological materials.
상세보기
Hubbell Jeffrey A. ; Pathak Chandrashekhar P. ; Sawhney Amarpreet S. ; Desai Neil P. ; Hossainy Syed F. A., Gels for encapsulation of biological materials.
상세보기
Hubbell, Jeffrey A.; Pathak, Chandrashekhar P.; Sawhney, Amarpreet S.; Desai, Neil P.; Hossainy, Syed F. A., Gels for encapsulation of biological materials.
상세보기
Rhee Woonza M. (Palo Alto CA) Berg Richard A. (Los Altos CA), Glycosaminoglycan-synthetic polymer conjugates.
상세보기
Coury Arthur J. ; Sawhney Amarpreet S. ; Hubbell Jeffrey A.,CHX ; Philbrook C. Michael, Hemostatic tissue sealants.
상세보기
Weissleder Ralph (Charlestown MA) Bogdanov Alexei (Newton MA), Hydrogel compositions and methods of use.
상세보기
Won, Chee-Youb; Zhang, Yeli; Chu, Chih-Chang, Hydrogel entrapping therapeutic agent and stent with coating comprising this.
상세보기
Ottoboni Thomas B. ; Jungherr Lisa B. ; Yamamoto Ronald K., Hydrogel-based microsphere drug delivery systems.
상세보기
Won, Chee-Youb; Zhang, Yeli; Chu, Chih-Chang, Hydrogel-forming system with hydrophobic and hydrophilic components.
상세보기
Won, Chee-Youb; Zhang, Yeli; Chu, Chih-Chang, Hydrogel-forming system with hydrophobic and hydrophilic components.
상세보기
Shalaby Shalaby W., Hydrogel-forming, self-solvating absorbable polyester copolymers, and methods for use thereof.
상세보기
Shalaby W. Shalaby, Hydrogel-forming, self-solvating absorbable polyester copolymers, and methods for use thereof.
상세보기
Jamiolkowski Dennis D. ; Bezwada Rao S., Hydrogels containing absorbable polyoxaamides.
상세보기
Coury Arthur J. ; Avila Luis Z. ; Pathak Chandrashekhar P. ; Barman Shikha P., Hydroxy-acid cosmetics.
상세보기
Houki Yoji (Kawasaki JPX) Matsuoka Makoto (Kawasaki JPX) Kojima Takeo (Kawasaki JPX) Takahashi Akira (Kawasaki JPX) Furukawa Mitsuhito (Ryouzen-machi JPX) Kera Hiroshi (Fukushima JPX), Image forming apparatus having contact type, one-component developing unit.
상세보기
Hubbell,Jeffrey A.; Pathak,Chandrashekhar P.; Sawhney,Amarpreet S.; Desai,Neil P.; Hill,Jennifer L.; Hossainy,Syed F. A., Implantable substrate coated with a macromer having free radical polymerizable substituents.
상세보기
Rhee Woonza (Palo Alto CA) Wallace Donald G. (Menlo Park CA) Michaels Alan S. (Boston MA) Burns ; Jr. Ramon A. (Fremont CA) Fries Louis (Los Altos CA) DeLustro Frank (Belmont CA) Bentz Hanne (Newark , Implants coated with collagen-polymer conjugates.
상세보기
Sawhney, Amarpreet S., In situ polymerizable hydrogels.
상세보기
Ni, Yawei; Yates, Kenneth M., In-situ gel formation of pectin.
상세보기
Li Leping ; Gilhooly James Albert ; Morgan ; III Clifford Owen ; Wei Cong ; Yu Chienfan, Indirect endpoint detection by chemical reaction.
상세보기
Melanson David A. ; Sawhney Amarpreet S. ; Levine Marc Alan ; Spiridigliozzi John C. ; Bromander Thomas S., Initiator priming for improved adherence of gels to substrates.
상세보기
Wallace Donald G. (Menlo Park CA) Reihanian Hertsel (San Francisco CA) Pharriss Bruce B. (Palo Alto CA) Braun William G. (Los Altos CA), Injectable implant composition having improved intrudability.
상세보기
Rhee Woonza M. ; Berg Richard A. ; Chu George H. ; DeLustro Frank A. ; Jolivette Dan M. ; McCullough Kimberly A., Injectable or implantable biomaterials for filling or blocking lumens and voids of the body.
상세보기
Horton Joseph A. ; Vincent Diana Joan, Insitu formable and self-forming intravascular flow modifier (IFM) and IFM assembly for deployment of same.
상세보기
Rogers Russell L. (Munith MI) Turk Rodney E. (W. Bloomfield MI), Intraluminal stenting graft.
상세보기
Lazarus Harrison M. (853 Thirteenth Ave. Salt Lake City UT 84103), Intraluminal vascular graft.
상세보기
Harris J. Milton (Huntsville AL), Isolatable, water soluble, and hydrolytically stable active sulfones of poly(ethylene glycol) and related polymers for m.
상세보기
Dunshee Wayne K. ; Peterson Donald G. ; Niven ; Jr. Clarence A. ; Riedel John E., Medical adhesive composite and package.
상세보기
Opolski Margaret P. (Fort Polk LA), Medical apparatus having protective, lubricious coating.
상세보기
Rockey Arthur G. (3438 Sharon Rd. Charlotte NC 28211), Medical sleeve.
상세보기
Viegas Tacey X. (Canton MI) Reeve Lorraine E. (Dexter MI) Henry Raymond L. (Grosse Pointe Woods MI), Medical uses of in situ formed gels.
상세보기
Sawhney Amarpreet S. ; Campbell Patrick K. ; Melanson David A., Method and apparatus for in situ formation of hydrogels.
상세보기
Jones Michael L. ; Greff Richard J., Method and apparatus for intravasculer embolization.
상세보기
Mazzocchi, Rudy, Method and apparatus for occluding aneurysms.
상세보기
Hugh H. Trout, III ; Howard M. Tanner, Method and apparatus for supporting a graft assembly.
상세보기
Rudy Michael A. (Rochester NY), Method and compositions for enhancing white blood cell functioning on a mucosal or cutaneous surface.
상세보기
Kupiecki David (Cupertino CA) Han Thuzar K. (Fremont CA), Method for coating catheter lumens.
상세보기
Fogarty Thomas J. ; Freislinger Kirsten ; Weinberg Steven ; Cox Brian J. ; Evans Michael A. ; Kim Steven W. ; Lenker Jay A., Method for deploying cuff prostheses.
상세보기
Chinn, Joseph A.; Phillips, Jr., Richard E.; Sauter, Joseph A.; Casanova, R. Michael; Pathak, Chandrashekhar P.; Moore, Mark A.; Bruce, L. Diane, Method for producing antimicrobial antithrombogenic medical devices.
상세보기
Korteweg, Wayne; Korteweg, George P., Method for producing surgical sponge device and product thereof.
상세보기
Folkman Judah M. (Brookline MA), Method for retaining ophthalmological agents in ocular tissues.
상세보기
Pathak Chandrashekhar P. ; Moore Mark A. ; Philips ; Jr. Richard E., Method for treating cross-linked biological tissues.
상세보기
Embleton Jonathan Kenneth,GBX, Method for treating ophthalmic disease through fast dispersing dosage forms.
상세보기
Rhee Woonza (Palo Alto CA) Wallace Donald G. (Menlo Park CA) Michaels Alan S. (Boston MA) Burns ; Jr. Ramon A. (Fremont CA) Fries Louis (Los Altos CA) DeLustro Frank (Belmont CA) Bentz Hanne (Newark , Method of augmenting tissue with collagen-polymer conjugates.
상세보기
Pathak, Chandrashekhar P.; Moore, Mark A.; Phillips, Jr., Richard E., Method of cross-linking tissue with a bis-maleimide compound.
상세보기
Rhee Woonza M. (Palo Alto CA) Berg Richard A. (Los Altos CA) Rosenblatt Joel S. (Palo Alto CA) Tefft Jacqueline A. (Redwood City CA) Braga Larry J. (Fremont CA) Smestad Thomas L. (Palo Alto CA), Method of preparing crosslinked biomaterial compositions for use in tissue augmentation.
상세보기
Rhee Woonza M. (Palo Alto CA) Berg Richard A. (Los Altos CA) Rosenblatt Joel S. (Palo Alto CA) Tefft Jacqueline A. (Redwood City CA) Braga Larry J. (Fremont CA) Smestad Thomas L. (Palo Alto CA), Method of preparing crosslinked biomaterial compositions for use in tissue augmentation.
상세보기
Hodd, Kenneth A.; Dillingham, Keith Alfred; de Groot, Jacqueline, Method of producing intraocular lenses in vivo.
상세보기
Rhee Woonza M. ; DeLustro Frank A. ; Berg Richard A., Method of using crosslinked polymer compositions in tissue treatment applications.
상세보기
Fogarty Thomas J. ; Lenker Jay A. ; Cox Brian J. ; Will Allan R. ; Freislinger Kirsten, Methods and apparatus for conformably sealing prostheses within body lumens.
상세보기
Fogarty, Thomas J.; Lenker, Jay A.; Cox, Brian J.; Will, Allan R.; Freislinger, Kirsten, Methods and apparatus for conformably sealing prostheses within body lumens.
상세보기
Sawhney Amarpreet S., Methods and apparatus for in situ formation of hydrogels.
상세보기
Sawhney, Amarpreet S., Methods and apparatus for in situ formation of hydrogels.
상세보기
Amarpreet S. Sawhney ; John Spiridigliozzi, Methods and apparatus for intraluminal deposition of hydrogels.
상세보기
Sawhney Amarpreet S., Methods and apparatus for intraluminal deposition of hydrogels.
상세보기
Sawhney, Amarpreet S.; Spiridigliozzi, John, Methods and apparatus for intraluminal deposition of hydrogels.
상세보기
Sawhney,Amarpreet S.; Spiridigliozzi,John, Methods and apparatus for intraluminal deposition of hydrogels.
상세보기
Beck Jon E., Methods and apparatus for ocular iontophoresis.
상세보기
Khosravi, Farhad; Abolfathi, Amir; Hogendijk, Michael, Methods and apparatus for treating aneurysms and arterio-venous fistulas.
상세보기
Schwartz Daniel M. ; Hubbell Jeffrey A.,CHX ; Irvine Alexander R., Methods and pharmaceutical compositions for the closure of retinal breaks.
상세보기
Sawhney, Amarpreet S., Methods for forming regional tissue adherent barriers and drug delivery systems.
상세보기
Sawhney,Amarpreet S., Methods for forming regional tissue adherent barriers and drug delivery systems.
상세보기
Pathak Chandrashekhar P. ; Sawhney Amarpreet S. ; Hubbell Jeffrey A. ; Herman Stephen J. ; Roth Laurence A. ; Campbell Patrick K. ; Berrigan Kevin M. ; Jarrett Peter K. ; Coury Arthur J., Methods for intraluminal photothermoforming.
상세보기
Hubbell Jeffrey A. (Austin TX) Elbert Donald (Austin TX) Hill-West Jennifer L. (Austin TX) Drumbeller Paul D. (Austin TX) Chowdhury Sanghamitra (Round Rock TX) Sawhney Amarpreet (Newtown MA), Methods for modifying cell contact with a surface.
상세보기
Sehl, Louis C.; Trollsas, Olof Mikael; Wallace, Donald G.; Toman, David; DeLustro, Frank A.; Schroeder, Jacqueline A.; Chu, George H., Methods for tissue repair using adhesive materials.
상세보기
Hodd,Kenneth A.; Dillingham,Keith Alfred; de Groot,Jacqueline, Methods of producing intraocular lenses.
상세보기
Sawhney, Amarpreet S., Methods of using in situ hydration of hydrogel articles for sealing or augmentation of tissue or vessels.
상세보기
Rourke Jonathan M. ; Yang Yi, Micro-porous mesh stent with hybrid structure.
상세보기
Shah Kishore R. (Chelmsford MA), Microphase separated hydrogels for controlled release of bioactive materials.
상세보기
Yagi Takayuki,JPX, Microstructure and method of forming the same.
상세보기
Fogarty Thomas J. ; Freislinger Kirsten ; Weinberg Steven ; Cox Brian J. ; Evans Michael A. ; Kim Steven W. ; Lenker Jay A., Modular intraluminal prosteheses construction and methods.
상세보기
Fogarty Thomas J. ; Freislinger Kirsten ; Weinberg Steven ; Cox Brian J. ; Evans Michael A. ; Kim Steven W. ; Lenker Jay A., Modular intraluminal prostheses construction and methods.
상세보기
Harris J. Milton ; Veronese Francesco Maria,ITX ; Caliceti Paolo,ITX ; Schiavon Oddone,ITX, Multiarmed, monofunctional, polymer for coupling to molecules and surfaces.
상세보기
Chandrashekhar P. Pathak ; Shikha P. Barman ; C. Michael Philbrook ; Amarpreet S. Sawhney ; Arthur J. Coury ; Luis Z. Avila ; Mark T. Kieras, Multiblock biodegradable hydrogels for drug delivery and tissue treatment.
상세보기
Pathak Chandrashekhar P. ; Barman Shikha P. ; Philbrook C. Michael ; Sawhney Amarpreet S. ; Coury Arthur J. ; Avila Luis Z. ; Kieras Mark T., Multiblock biodegradable hydrogels for drug delivery and tissue treatment.
상세보기
Pathak, Chandrashekhar P.; Barman, Shikha P.; Philbrook, C. Michael; Sawhney, Amarpreet S.; Coury, Arthur J.; Avila, Luis Z.; Kieras, Mark T., Multiblock biodegradable hydrogels for drug delivery and tissue treatment.
상세보기
Pathak, Chandrashekhar P.; Barman, Shikha P.; Philbrook, C. Michael; Sawhney, Amarpreet S.; Coury, Arthur J.; Avila, Luis Z.; Kieras, Mark T., Multiblock biodegradable hydrogels for drug delivery and tissue treatment.
상세보기
Hubbell Jeffrey A. (Austin TX) Elbert Donald (Austin TX) Hill-West Jennifer L. (Austin TX) Drumheller Paul D. (Austin TX) Chowdhury Sanghamitra (Round Rock TX) Sawhney Amarpreet (Newton MA), Multifunctional organic polymers.
상세보기
Hubbell Jeffrey A. (Austin TX) Elbert Donald (Austin TX) Hill-West Jennifer L. (Austin TX) Drumheller Paul D. (Austin TX) Chowdhury Sanghamitra (Round Rock TX) Sawhney Amarpreet (Newton MA), Multifunctional organic polymers.
상세보기
Hubbell Jeffrey A. ; Elbert Donald ; Hill-West Jennifer L. ; Drumheller Paul D. ; Chowdhury Sanghamitra ; Sawhney Amarpreet S., Multifunctional organic polymers.
상세보기
Meadows David L. (Mission Viejo CA), Nonaqueous thixotropic drug delivery suspensions and methods of their use.
상세보기
Darougar Sohrab,GBX ; Darougar Dayshad,GBX, Ocular insert.
상세보기
Darougar Sohrab (2 Digby Place Croydon CR0 5RQ GB2), Ocular insert for the fornix.
상세보기
Darougar Sohrab (2 Digby Pl. Croydon CR0 5QR NJ GB2) Weiner Alan L. (28 Priory Rd. Cranburry NJ 08512), Ocular insert with anchoring protrusions.
상세보기
Darougar Sohrab (Croydon NJ GB2) Weiner Alan L. (Cranburry NJ), Ocular insert with anchoring protrusions.
상세보기
Darougar Sohrab,GBX ; Weiner Alan L. ; Bhatt Padmanabh Pravinchandra ; Raul Victor Albert ; Gantner David Clayton, Ocular insert with anchoring protrusions.
상세보기
Beck, Jon E.; Koss, Alex, Ocular iontophoretic apparatus.
상세보기
Jungherr Lisa B. ; Ottoboni Thomas B., Ocular microsphere delivery system.
상세보기
Chang, James; Hughes, Patrick, Oil-in-water method for making alpha-2 agonist polymeric drug delivery systems.
상세보기
Sawaya Assad S., Ophthalmic aqueous gel formulation and related methods.
상세보기
Cohen Smadar,ILX ; Lobel Esther,ILX, Ophthalmic delivery system.
상세보기
Chandler Lamar ; Salz James J., Ophthalmic surgical sponge for protection of a corneal cap.
상세보기
Smalling, Richard W., Percutaneous implantation of partially covered stents in aneurysmally dilated arterial segments with subsequent embolization and obliteration of the aneurysm cavity.
상세보기
Buscemi Paul J. ; Bilge Fertac ; Holman Thomas J., Percutaneous repair of cardiovascular anomalies and repair compositions.
상세보기
Wong Sui-Ming ; Cooper Eugene R. ; Xu Shuqian, Pharmaceutical compositions containing polyalkylene block copolymers which gel at physiological temperature.
상세보기
Hubbell Jeffrey A. (Austin TX) Pathak Chandrashekhar P. (Waltham MA) Sawhney Amarpreet S. (Newton MA) Desai Neil P. (Los Angeles CA) Hill Jennifer L. (Austin TX), Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers.
상세보기
Hubbell Jeffrey A. (Austin TX) Pathak Chandrashekhar P. (Waltham MA) Sawhney Amarpreet S. (Newton MA) Desai Neil P. (Los Angeles CA) Hill Jennifer L. (Austin TX), Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers.
상세보기
Hubbell Jeffrey A. (Austin TX) Pathak Chandrashekhar P. (Waltham MA) Sawhney Amarpreet S. (Newton MA) Desai Neil P. (Los Angeles CA) Hill-West Jennifer L. (Austin TX), Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers.
상세보기
Hubbell Jeffrey A. ; Pathak Chandrashekhar P. ; Sawhney Amarpreet S. ; Desai Neil P. ; Hill Jennifer L., Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers.
상세보기
Hubbell Jeffrey A. ; Pathak Chandrashekhar P. ; Sawhney Amarpreet S. ; Desai Neil P. ; Hill-West Jennifer L., Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers.
상세보기
Hubbell Jeffrey A. ; Pathak Chandrashekhar P. ; Sawhney Amarpreet S. ; Desai Neil P. ; Hill-West Jennifer L., Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers.
상세보기
Hubbell, Jeffrey A.; Pathak, Chandrashekhar P.; Sawhney, Amarpreet S.; Desai, Neil P.; Hill, Jennifer L., Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers.
상세보기
Johnson ; Leighton Clifford, Pipette.
상세보기
Coury Arthur J. ; Avila Luis Z. ; Pathak Chandrashekhar P. ; Barman Shikha P., Poly(hydroxy acid)/polymer conjugates for skin applications.
상세보기
Rhee Woonza (Palo Alto CA) Wallace Donald G. (Menlo Park CA) Michaels Alan S. (Boston MA) Burns ; Jr. Ramon A. (Fremont CA) Fries Louis (Los Altos CA) DeLustro Frank (Belmont CA) Bentz Hanne (Newark , Polymer conjugates ophthalmic devices comprising collagen-polymer conjugates.
상세보기
Pathak Chandrashekhar P. ; Sawhney Amarpreet S. ; Hubbell Jeffrey A. ; Herman Stephen J. ; Roth Laurence A. ; Campbell Patrick K. ; Berrigan Kevin M. ; Jarrett Peter K. ; Coury Arthur J., Polymeric article for intraluminal photothermoforming.
상세보기
Pohlmann Thomas (Niedernberg DEX) Muller Achim (Aschaffenburg DEX) Seiferling Bernhard (Goldbach DEX), Polymeric networks from water-soluble prepolymers.
상세보기
Sawhney Amarpreet S. ; Enscore David J. ; Goodrich Stephen D. ; Nason William C. ; Yao Fei ; Weaver Douglas ; Jarrett Peter K. ; Coury Arthur J. ; Rudowsky Ronald S. ; Powell Michelle D. ; Avila Luis, Polymerizable biodegradable polymers including carbonate or dioxanone linkages.
상세보기
Sawhney Amarpreet S. ; Jarrett Peter K. ; Coury Arthur J. ; Rudowsky Ronald S. ; Powell Michelle D. ; Avila Luis Z. ; Enscore David J. ; Goodrich Stephen D. ; Nason William C. ; Yao Fei ; Weaver Doug, Polymerizable biodegradable polymers including carbonate or dioxanone linkages.
상세보기
Sawhney,Amarpreet S.; Jarrett,Peter K.; Coury,Arthur J.; Rudowsky,Ronald S.; Lyman,Michelle D.; Avila,Luis Z.; Enscore,David J.; Goodrich,Stephen D.; Nason,William C.; Yao,Fei; Weaver,Douglas; Barman, Polymerizable biodegradable polymers including carbonate or dioxanone linkages.
상세보기
Cohn Daniel (Jerusalem ILX) Yitzchaiek Shlomo (Ramat Gan ILX) Bilenkis Sophie (Jerusalem ILX), Polyurethane-based polymeric materials and biomedical articles and pharmaceutical compositions utilizing the same.
상세보기
Ramstack J. Michael (Lebanon OH) Herbert Paul F. (Wayland MA) Strobel Jan (Westchester OH) Atkins Thomas J. (Cincinnati OH), Preparation of biodegradable microparticles containing a biologically active agent.
상세보기
De Luca Patrick P. (Lexington KY) Rypacek Frantisek (Leckova CZX), Preparation of biodegradable microspheres useful as carriers for macromolecules.
상세보기
Kuzma Petr (Monmouth Junction NJ) Moro Daniel G. (Randolph NJ) Quandt Harry (North Middletown NJ), Preparation of homogeneous hydrogel copolymers.
상세보기
Masayo Higashiyama JP; Akira Ohtori JP, Prolonged-action eye drop.
상세보기
Rhodes Valentine J., Prostheses for aneurysmal and/or occlusive disease at a bifurcation in a vessel, duct, or lumen.
상세보기
McDermott John D. ; Renzi David ; Layne Richard W. ; Banas Christopher E., Prosthesis for abdominal aortic aneurysm repair.
상세보기
Pathak,Chandrashekhar P., Proteinaceous gels having visualization agents and methods of use thereof.
상세보기
Turnlund Todd H. ; Sweet William L., Radioactive intraluminal endovascular prosthesis and method for the treatment of aneurysms.
상세보기
Wallace Donald G. ; Cruise Gregory M. ; Rhee Woonza M. ; Schroeder Jacqueline Anne ; Coker ; III George T. ; Maroney Marcee M., Rapid gelling biocompatible polymer composition.
상세보기
Wallace, Donald G.; Cruise, Gregory M.; Rhee, Woonza M.; Schroeder, Jacqueline Anne; Coker, III, George T.; Maroney, Marcee M.; Trollsas, Olof Mikael, Rapid-gelling biocompatible polymer composition and associated methods of preparation and use.
상세보기
Sawhney Amarpreet S. ; Melanson David A. ; Pathak Chandrashekar P. ; Hubbell Jeffrey A. ; Avila Luis Z. ; Kieras Mark T. ; Goodrich Stephen D. ; Barman Shikha P. ; Coury Arthur J. ; Rudowsky Ronald S, Redox and photoinitiator priming for improved adherence of gels to substrates.
상세보기
Sawhney Amarpreet S. ; Melanson David A. ; Pathak Chandrashekar P. ; Hubbell Jeffrey A. ; Avila Luis Z. ; Kieras Mark T. ; Goodrich Stephen D. ; Barman Shikha P. ; Coury Arthur J. ; Rudowsky Ronald S, Redox and photoinitiator systems for priming and improved adherence of gels to substrates.
상세보기
Amarpreet S. Sawhney ; David A. Melanson ; Chandrashekar P. Pathak ; Jeffrey A. Hubbell ; Luis Z. Avila ; Mark T. Kieras ; Stephen D. Goodrich ; Shikha P. Barman ; Arthur J. Coury ; Ronald S, Redox and photoinitiator systems for priming for improved adherence of gels to substrates.
상세보기
Poff Bradley C. ; Herman Stephen J. ; Pichon Dean M. ; Sawhney Amarpreet S., Retracting tissue using photoadhering adhesive.
상세보기
Harris J. Milton, Soluble, degradable poly(ethylene glycol) derivatives for controllable release of bound molecules into solution.
상세보기
Lonneman Alan (Plymouth MN) Miller Curtis H. (Burnsville MN), Sprayer assembly for physiologic glue.
상세보기
Dahms Gerd H.,DEX, Stable multiple X/O/Y-emulsion.
상세보기
Hall Todd A. ; Furnish Greg R. ; Furnish Simon M. ; Wolf Scott J. ; Wilk Peter J. ; Phelps David Y. ; Pompili Vincent, Stent delivery system and method of use.
상세보기
Matsuda Takehisa (Minoo JPX) Iwata Hiroo (Suita JPX) Itoh Tetsuo (Shiga JPX), Surgical adhesive.
상세보기
Sawhney, Amarpreet S.; Ransone, II, William H.; Singhal, Mukesh, Surgical delivery system for medical sealant.
상세보기
Maitra, Amarnath; Gupta, Ajay Kumar; Majumdar, Dipak; Madan, Sumit, Sustained release and long residing ophthalmic formulation and the process of preparing the same.
상세보기
Fischer Dan E. (Sandy UT), Syringe apparatus with detachable mixing and delivery tip.
상세보기
Barta Helmut (Vienna ATX) Eder Helmut (Vienna ATX) Granser Manfred (Vienna ATX) Habison Georg (Vienna ATX) Hantak Edith (Seebarn ATX) Moser Franz (Deutsch Wagram ATX) Pfaffenbichler Peter (Podersdorf, Syringe assembly for the storage and application of a biological multi-component material.
상세보기
Shah Abhay S. ; Pathak Jogen ; Mitchell Bob ; Andrade Hugo A. ; DeKey Samson L. ; Brower Todd, System and method for handling events in an instrumentation system.
상세보기
Letort, Michel, System for transrenal/intraostial fixation of endovascular prosthesis.
상세보기
Clark Abbot F. ; Wordinger Robert J., TGF.alpha. for the treatment of ocular hypertension and glaucoma.
상세보기
Lowinger,Johan; Lowinger,Bruno; DeLustro,Frank; Cox,David; Browdie,David A., Tissue adhesive sealant.
상세보기
Pathak C. P. ; Moore Mark A. ; Phillips Richard E., Tissue crosslinking for bioprostheses using activated difunctional or polyfunctional acids.
상세보기
Dehdashtian, Mark; Allenberg, Jens, Towel graft means for enhancing tissue ingrowth in vascular grafts.
상세보기
Jeffrey A. Hubbell CH; Chandrashekhar P. Pathak ; Amarpreet Sawhney ; Neil Desai ; Syed Hossainy ; Jennifer L. Hill-West, Treating medical conditions by polymerizing macromers to form polymeric materials.
상세보기
Brazzell Romulus K. (New City NY) Dubnick Bernard (Westwood NJ), Treatment of glaucoma and ocular hypertension with b3-adrenergic agonists.
상세보기

IPC	Description
A	생활필수품
A62	인명구조; 소방(사다리 E06C)
A62B	인명구조용의 기구, 장치 또는 방법(특히 의료용에 사용되는 밸브 A61M 39/00; 특히 물에서 쓰이는 인명구조 장치 또는 방법 B63C 9/00; 잠수장비 B63C 11/00; 특히 항공기에 쓰는 것, 예. 낙하산, 투출좌석 B64D; 특히 광산에서 쓰이는 구조장치 E21F 11/00)
A62B-1/08	.. 윈치 또는 풀리에 제동기구가 있는 것

내보내기 구분	파일저장 인쇄 메일전송
구성항목	기본정보 상세정보 관리번호, 국가코드, 자료구분, 상태, 출원번호, 출원일자, 공개번호, 공개일자, 등록번호, 등록일자, 발명명칭(한글), 발명명칭(영문), 출원인(한글), 출원인(영문), 출원인코드, 대표IPC 관리번호, 국가코드, 자료구분, 상태, 출원번호, 출원일자, 공개번호, 공개일자, 공고번호, 공고일자, 등록번호, 등록일자, 발명명칭(한글), 발명명칭(영문), 출원인(한글), 출원인(영문), 출원인코드, 대표출원인, 출원인국적, 출원인주소, 발명자, 발명자E, 발명자코드, 발명자주소, 발명자 우편번호, 발명자국적, 대표IPC, IPC코드, 요약, 미국특허분류, 대리인주소, 대리인코드, 대리인(한글), 대리인(영문), 국제공개일자, 국제공개번호, 국제출원일자, 국제출원번호, 우선권, 우선권주장일, 우선권국가, 우선권출원번호, 원출원일자, 원출원번호, 지정국, Citing Patents, Cited Patents
저장형식	Text(ASCII format) Excel format PIAS분석(.xls)
메일정보	받는사람 (필수) @ 보내는사람 (선택) @ 제목 내용 KISTI 검색결과 이메일 서비스
안내	총 건의 자료가 검색되었습니다. 다운받으실 자료의 인덱스를 입력하세요. (1-10,000) 검색결과의 순서대로 최대 10,000건 까지 다운로드가 가능합니다. 데이타가 많을 경우 속도가 느려질 수 있습니다.(최대 2~3분 소요) 다운로드 파일은 UTF-8 형태로 저장됩니다. 파일의 내용이 제대로 보이지 않을실 때는 웹브라우저 상단의 보기 -> 인코딩 -> 자동선택 여부를 확인하십시오. ~ Text(ASCII format) Excel format

연합인증

Method for applying flowable hydrogels to a cornea 원문보기

초록 ▼

대표청구항 ▼

연구과제 타임라인

이 특허에 인용된 특허 (232)

관련 콘텐츠

특허 원문 보기

IPC 상위 출원인

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

선택된 텍스트

연합인증

Method for applying flowable hydrogels to a cornea 원문보기

초록 ▼

대표청구항 ▼

연구과제 타임라인

전체(0) 논문(0) 특허(0) 보고서(0)

전체(0) 논문(0) 특허(0) 보고서(0)

이 특허에 인용된 특허 (232)

관련 콘텐츠

특허 원문 보기

IPC 상위 출원인

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

선택된 텍스트