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A multicapillary sample preparation device, especially useful for handling biological samples, comprising a plurality of uniform capillary tubes coated with a stationary phase, and arranged in a monolithic element. The multicapillary device is suitable for attachment to a pipette, micropipette, syri

A multicapillary sample preparation device, especially useful for handling biological samples, comprising a plurality of uniform capillary tubes coated with a stationary phase, and arranged in a monolithic element. The multicapillary device is suitable for attachment to a pipette, micropipette, syringe, or other analytical or sample preparation instrument.

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1. A method for isolating nucleic acid, comprising: (a) loading a multicapillary element retained in or attached to a pipette, micropipette, pipette tip, or syringe device, with a loading solution comprising nucleic acid under conditions that permit adsorption of the nucleic acid to the inner wall o

1. A method for isolating nucleic acid, comprising: (a) loading a multicapillary element retained in or attached to a pipette, micropipette, pipette tip, or syringe device, with a loading solution comprising nucleic acid under conditions that permit adsorption of the nucleic acid to the inner wall of the capillaries, which multicapillary element comprises a plurality of parallel capillaries comprising a substantially imperforate inner wall;(b) discarding the loading solution from the device after (a); and(c) eluting the nucleic acid from the multicapillary element after (b), whereby the nucleic acid is isolated from the loading solution. 2. The method of claim 1, wherein the device comprises a plastic, glass, fused silica, ceramic, or stainless steel. 3. The method of claim 2, wherein the plastic is formed from polyetheretherketone, polystyrene, polypropylene or polyethylene. 4. The method of claim 3, wherein the device is formed from polypropylene. 5. The method of claim 1, wherein the device is a pipette tip. 6. The method of claim 5, wherein the pipette tip is formed from polystyrene, polypropylene or polyethylene. 7. The method of claim 6, wherein the pipette tip is formed from polypropylene. 8. The method of claim 1, wherein the capillaries are substantially cylindrical. 9. The method of claim 1, wherein the cross section of the capillaries is substantially polygonal. 10. The method of claim 1, wherein the cross section of the capillaries is substantially hexagonal. 11. The method of claim 1, wherein the multicapillary element comprises fused silica, glass, ceramic, stainless steel, polystyrene, polypropylene, polyethylene, or polyetheretherketone. 12. The method of claim 11, wherein the multicapillary element consists of fused silica. 13. The method of claim 11, wherein the multicapillary element consists of glass. 14. The method of claim 1, wherein an inner diameter of each capillary is about 0.1 micrometers to about 200 micrometers. 15. The method of claim 1, wherein an outer diameter of the multicapillary element is about 1 mm to about 20 mm. 16. The method of claim 1, wherein the length of the multicapillary element is about 1 mm to about 250 mm. 17. The method of claim 1, wherein the volume of the device is about 1 microliter to about 100 microliters. 18. The method of claim 1, wherein the inner wall of the capillaries includes particles of inert material. 19. The method of claim 1, wherein the inner wall of the capillaries includes a nodular surface. 20. The method of claim 1, wherein the inner wall of the capillaries is etched. 21. The method of claim 1, wherein the nucleic acid comprises deoxyribonucleic acid (DNA). 22. The method of claim 1, wherein the nucleic acid comprises ribonucleic acid (RNA). 23. The method of claim 1, wherein the nucleic acid isolated is sheared less than nucleic acid isolated from a device that includes porous silica. 24. The method of claim 1, further comprising washing the multicapillary element after the loading solution is discarded and before the nucleic acid is eluted from the multicapillary element. 25. The method of claim 1, wherein the inner surface of each capillary comprises an insoluble stationary phase coated directly on the inner wall of the capillaries. 26. The method of claim 25, wherein the stationary phase comprises C18.