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Kafe 바로가기국가/구분 | United States(US) Patent 등록 |
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국제특허분류(IPC7판) |
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출원번호 | US-0085398 (2013-11-20) |
등록번호 | US-8983602 (2015-03-17) |
발명자 / 주소 |
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출원인 / 주소 |
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대리인 / 주소 |
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인용정보 | 피인용 횟수 : 3 인용 특허 : 454 |
Approaches for selecting an electrode combination of multi-electrode pacing devices are described. Electrode combination parameters that support cardiac function consistent with a prescribed therapy are evaluated for each of a plurality of electrode combinations. Electrode combination parameters tha
Approaches for selecting an electrode combination of multi-electrode pacing devices are described. Electrode combination parameters that support cardiac function consistent with a prescribed therapy are evaluated for each of a plurality of electrode combinations. Electrode combination parameters that do not support cardiac function are evaluated for each of the plurality of electrode combinations. An order is determined for the electrode combinations based on the parameter evaluations. An electrode combination is selected based on the order, and therapy is delivered using the selected electrode combination.
1. A method comprising: delivering electrical stimulation to a patient's heart using a plurality of cardiac electrodes supported inside the patient by one or more at least partially implanted leads and an evaluation unit having an analyzer circuit that is external of the patient and attached to the
1. A method comprising: delivering electrical stimulation to a patient's heart using a plurality of cardiac electrodes supported inside the patient by one or more at least partially implanted leads and an evaluation unit having an analyzer circuit that is external of the patient and attached to the one or more leads;receiving user-determined electrode combination selection criteria from a user via the evaluation unit;evaluating, for each electrode combination of a plurality of electrode combinations of the plurality of cardiac electrodes, one or more first parameters and one or more second parameters produced by the electrical stimulation delivered using the electrode combination, the first parameters supportive of cardiac function consistent with a prescribed therapy and the second parameters not supportive of cardiac function consistent with the prescribed therapy;selecting one or more electrode combinations of the plurality of cardiac electrodes based, at least in part, on the user-determined electrode combination selection criteria; andprogramming an implantable pacing circuit to deliver a cardiac pacing therapy that preferentially uses the selected one or more electrode combinations relative to other electrode combinations of the plurality of cardiac electrodes. 2. The method of claim 1, wherein evaluating the one or more first parameters comprises evaluating a capture threshold for each of the plurality of electrode combinations, and wherein evaluating the one or more second parameters comprises evaluating extra-cardiac stimulation for each of the plurality of electrode combinations. 3. The method of claim 1, wherein evaluating the one or more first parameters comprises evaluating a responsiveness to cardiac resynchronization. 4. The method of claim 1, wherein evaluating the one or more second parameters comprises detecting at least one of unintended nerve stimulation and unintended muscle stimulation. 5. The method of claim 1, wherein the user-determined electrode combination selection criteria indicate one or more boundary conditions comprising one or more of a maximum pulse amplitude at which the implantable pacing circuit is programmed to deliver, a minimum pulse amplitude at which the implantable pacing circuit is programmed to deliver, a maximum pulse width at which the implantable pacing circuit is programmed to deliver, a minimum pulse amplitude at which the implantable pacing circuit is programmed to deliver. 6. The method of claim 1, wherein the user-determined electrode combination selection criteria indicate which electrode combinations of the plurality of cardiac electrodes will be evaluated. 7. The method of claim 1, further comprising: determining a ranking for at least some of the electrode combinations of the plurality of electrode combinations based on the evaluations of the one or more first parameters and the one or more second parameters for each electrode combination of the plurality of electrode combinations, wherein the one or more electrode combinations of the plurality of cardiac electrodes based are selected based, at least in part, on the ranking. 8. The method of claim 7, further comprising detecting a change in a patient's condition, wherein programming the implantable pacing circuit to deliver the cardiac pacing therapy further comprises programming the implantable pacing circuit to switch delivery of the cardiac pacing therapy from a first prioritized electrode combination of the ranking to a lower prioritized electrode combination of the ranking in response to the detected change in the patient's condition. 9. The method of claim 7, wherein determining the ranking of at least some electrode combinations comprises ranking at least some electrode combinations based on one or more of capture threshold, therapy energy consumption, undesirable activation of nerve or muscle tissue, anodal cardiac stimulation, degree of responsiveness to resynchronization therapy, impedance, cardiac contractility, electrode combination activation timing, cardiac output, stroke volume, dP/dt, hemodynamics, and historical success of therapy using the electrode combinations. 10. The method of claim 1, wherein evaluating the one or more first parameters comprises evaluating for each electrode combination two or more different first parameters associated with electrical stimulation delivered using the corresponding electrode combination, the two or more different first parameters supportive of cardiac function consistent with the prescribed therapy. 11. The method of claim of claim 1, further comprising: displaying for each of two or more of the plurality of electrode combinations, one or more of the first parameters and one or more of the second parameters on an electronic display;accepting a user input from a user; andranking the two or more of the plurality of electrode combinations on the display based, at least in part, on the user input and the evaluations of the first parameters and the second parameters for each of the two or more of the plurality of electrode combinations. 12. The method of claim 1, further comprising detecting a change in a patient's condition, wherein programming the implantable pacing circuit to deliver the cardiac pacing therapy further comprises programming the implantable pacing circuit to switch delivery of the cardiac pacing therapy from a first electrode combination to a second electrode combination based on the evaluations of the one or more first parameters and the one or more second parameters for each electrode combination of the plurality of electrode combinations in response to the detected change in the patient's condition. 13. A method comprising: delivering electrical stimulation to a patient's heart using a plurality of cardiac electrodes;receiving user-determined electrode combination selection criteria from a user, and storing the user-determined electrode combination selection criteria;evaluating, for each electrode combination of a plurality of electrode combinations of the plurality of cardiac electrodes, which electrode combination best satisfies the user-determined electrode combination selection criteria, by delivering electrical stimulation to the patient's heart using each electrode combination of the plurality of electrode combinations;selecting the electrode combination that best satisfies the user-determined electrode combination selection criteria; anddeliver a cardiac pacing therapy to the patient's heart that uses the selected electrode combination. 14. The method of claim 13, further comprising: detecting a condition that triggers an electrode combination update;repeating the evaluating and selecting steps in response to detecting the condition. 15. The method of claim 14, wherein the condition comprises one or more of loss of capture, change in posture, change in disease state, detection of non-therapeutic activation, and change in patient activity. 16. The method of claim 13, further determining a ranking for at least some of the electrode combinations of the plurality of electrode combinations based on the evaluations of which electrode combination best satisfies the user-determined electrode combination selection criteria. 17. The method of claim 13, further comprising automatically selecting the electrode combination that best satisfies the user-determined electrode combination selection criteria. 18. A method comprising: delivering electrical stimulation to a patient's heart using a plurality of cardiac electrodes supported inside the patient;receiving user-determined electrode combination selection criteria from a user via a user interface, and storing the user-determined electrode combination selection criteria in a memory;identifying, for each electrode combination of a plurality of electrode combinations of the plurality of cardiac electrodes, one or more electrode combinations that are not supportive of cardiac function consistent with the prescribed therapy by delivering electrical stimulation to the patient's heart using each electrode combination, resulting in one or more non-supportive electrode combinations;for each of the plurality of electrode combinations that are not identified as non-supportive electrode combinations, evaluating which of the electrode combination(s) satisfy the user-determined electrode combination selection criteria;selecting an electrode combination that satisfies the user-determined electrode combination selection criteria; andprogramming an implantable pacing circuit to deliver a cardiac pacing therapy to the patient's heart that uses the selected electrode combination. 19. The method of claim 18, wherein the user-determined electrode combination selection criteria comprises a capture threshold. 20. The method of claim 19, wherein an electrode combination is not supportive of cardiac function consistent with the prescribed therapy if it results in extra-cardiac stimulation of one or more of a nerve or a muscle.
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