최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
DataON 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Edison 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Kafe 바로가기국가/구분 | United States(US) Patent 등록 |
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국제특허분류(IPC7판) |
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출원번호 | US-0549313 (2012-07-13) |
등록번호 | US-8986209 (2015-03-24) |
발명자 / 주소 |
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출원인 / 주소 |
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대리인 / 주소 |
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인용정보 | 피인용 횟수 : 0 인용 특허 : 595 |
The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
1. A system for monitoring glucose concentration in a host, the system comprising: a substantially continuous glucose sensor configured to produce sensor data indicative of a glucose concentration in a host;a communications module configured to receive the sensor data from the substantially continuo
1. A system for monitoring glucose concentration in a host, the system comprising: a substantially continuous glucose sensor configured to produce sensor data indicative of a glucose concentration in a host;a communications module configured to receive the sensor data from the substantially continuous glucose sensor and to receive reference data from an in vitro single point glucose monitor, the reference data indicative of a measured glucose concentration in a biological sample from the host, wherein the receiver comprises:a processor module; anda computer readable memory comprising: instructions configured to cause the processor module to determine a rate of change of the glucose concentration in the host at a time corresponding to the measured glucose concentration in the biological sample;instructions configured to cause the processor module to determine a time lag between the sensor data and the reference data based at least in part on the determined rate of change;instructions configured to cause the processor module to form a matched data pair by matching one or more sensor data points of the sensor data with one or more data points of the reference data using the determined time lag; andinstructions configured to cause the processor module to calibrate the sensor data, wherein calibrating the sensor data is based at least in part on the matched data pair. 2. The system of claim 1, wherein the instructions configured to cause the processor module to calibrate the sensor data comprise instructions for prospective calibration of the sensor data. 3. The system of claim 1, wherein the instructions configured to cause the processor module to calibrate the sensor data comprise instructions configured to calibrate during initialization of the substantially continuous glucose sensor. 4. The system of claim 1, wherein the instructions configured to cause the processor module to calibrate the glucose data comprise instructions configured to calibrate after initialization of the substantially continuous glucose sensor. 5. The system of claim 1, wherein the instructions configured to cause the processor module to calibrate the sensor data comprise instructions configured to calibrate the sensor data based on reference data indicative of a single glucose concentration measured by the in vitro single point glucose monitor. 6. The system of claim 1, wherein the instructions configured to cause the processor module to calibrate the sensor data comprise instructions configured to calibrate the sensor data based on reference data indicative of more than one glucose concentration measured by the in vitro single point glucose monitor. 7. The system of claim 1, wherein the computer readable memory further comprises instructions configured to cause the processor module to filter the sensor data. 8. The system of claim 7, wherein the instructions configured to filter the sensor data are further configured to cause the processor module to adaptively filter the sensor data. 9. The system of claim 8, wherein the instructions configured to adaptively filter the sensor data are configured to cause the processor module to adaptively filter the sensor data based on a detection of signal artifacts. 10. The system of claim 8, wherein the instructions configured to adaptively filter the sensor data are configured to cause the processor module to adaptively filter the sensor data based on the rate of change of the calibrated sensor data. 11. The system of claim 7, wherein the instructions configured to calculate a rate of change are configured to cause the processor module to calculate a rate of change based on the filtered sensor data. 12. The system of claim 1, the communication module, the processor module, the instructions and the in vitro glucose monitor are integral with a hand-held computing device. 13. A system for monitoring glucose concentration in a host, the system comprising: a substantially continuous glucose sensor configured to produce sensor data indicative of a glucose concentration in a host;a communications module configured to receive the sensor data from the substantially continuous glucose sensor and to receive reference data from an in vitro single point glucose monitor, the in vitro single point glucose monitor configured to receive a biological sample from the host and to measure a glucose concentration in the sample, wherein the reference data is indicative of the measured glucose concentration in the sample;a processor module; anda computer readable memory comprising instructions that, when executed by the processor module, are configured to cause the processor module to: determine a rate of change of the host's glucose concentration based on the sensor data;determine a time lag between the sensor data and the glucose concentration measured by the in vitro single point glucose monitor using at least the determined rate of change; andcalibrate the sensor data received from the substantially continuous glucose sensor, wherein calibrating the sensor data comprises compensating for the time lag. 14. The system of claim 13, wherein the reference data includes a time stamp of the glucose concentration measured by the in vitro single point glucose monitor. 15. The system of claim 13, wherein the instructions configured to cause the processor module to calibrate the sensor data comprise instructions for prospective calibration. 16. The system of claim 13, wherein the instructions configured to cause the processor module to calibrate the sensor data comprise instructions configured to calibrate during initialization of the substantially continuous glucose sensor. 17. The system of claim 13, wherein the instructions configured to cause the processor module to calibrate the glucose data comprise instructions configured to calibrate after initialization of the substantially continuous glucose sensor. 18. The system of claim 13, wherein the instructions configured to cause the processor module to calibrate the sensor data comprise instructions configured to calibrate the sensor data based on a single glucose concentration measured by the in vitro single point glucose monitor. 19. The system of claim 13, wherein the instructions configured to cause the processor module to calibrate the sensor data comprise instructions configured to calibrate the sensor data based on more than one glucose concentration measured by the in vitro single point glucose monitor. 20. The system of claim 13, wherein the instructions are further configured to cause the processor module to filter the sensor data. 21. The system of claim 20, wherein the instructions configured to calculate a rate of change are configured to calculate a rate of change based on the filtered sensor data. 22. The system of claim 13, wherein the instructions configured to filter the sensor data are further configured to adaptively filter the sensor data. 23. The system of claim 21, wherein the instructions configured to adaptively filter the sensor data are configured to adaptively filter the sensor data based on a detection of signal artifacts. 24. The system of claim 21, wherein the instructions configured to adaptively filter the sensor data are configured to adaptively filter the sensor data based on the rate of change of the calibrated sensor data. 25. The system of claim 13, wherein the communication module, the processor module and the instructions are incorporated into a hand-held computing device.
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