The present invention relates to a polyurethane prepared from a mixture comprising: (a) at least one polyethylene glycol; (b) at least one di-isocyanate; (c) at least one polydialkyl siloxane diol; and (d) at least one diol of formula (I) wherein n is an integer from 1 to 25; wherein the polyethylen
The present invention relates to a polyurethane prepared from a mixture comprising: (a) at least one polyethylene glycol; (b) at least one di-isocyanate; (c) at least one polydialkyl siloxane diol; and (d) at least one diol of formula (I) wherein n is an integer from 1 to 25; wherein the polyethylene glycol, di-isocyanate, polydialkyl siloxane diol and diol are reacted under substantially anhydrous conditions. Further aspects of the invention relate to a process for preparing a polyurethane. The invention also relates to a process for preparing a polyurethane xerogel in the form of a molded article, said process comprising the steps of: (i) preparing a reaction mixture comprising at least one polyethylene glycol, at least one di-isocyanate, at least one polydialkyl siloxane diol and at least one diol of formula I as described above; (ii) reacting the reaction mixture formed in step (i) under substantially anhydrous conditions to form a polyurethane xerogel; and (iii) injection molding the polyurethane xerogel to form a molded article.
대표청구항▼
1. A polyurethane xerogel prepared from a mixture comprising: (a) at least one polyethylene glycol having a molecular weight of 1,000 to 50,000;(b) at least one di-isocyanate;(c) at least one polydialkyl siloxane diol; and(d) at least one diol of formula I wherein n is an integer from 1 to 10;wherei
1. A polyurethane xerogel prepared from a mixture comprising: (a) at least one polyethylene glycol having a molecular weight of 1,000 to 50,000;(b) at least one di-isocyanate;(c) at least one polydialkyl siloxane diol; and(d) at least one diol of formula I wherein n is an integer from 1 to 10;wherein the polyethylene glycol, di-isocyanate, polydialkyl siloxane diol and diol are reacted under substantially anhydrous conditions. 2. A polyurethane xerogel according to claim 1 wherein the di-isocyanate is an aliphatic di-isocyanate. 3. A polyurethane xerogel according to claim 1 wherein the di-isocyanate is of the formula OCN—R1—NCO, wherein R1 is a linear or branched C3-C18-alkylene, a C3-C8-cycloalkylene, a C3-C8-cycloalkylene-C1-C6-alkylene, a C3-C8-cycloalkylene-C1-C6-alkylene-C3-C8-cycloalkylene or a C1-C6-alkylene-C3-C8-cyclo-alkylene-C1-C6-alkylene. 4. A polyurethane xerogel according to claim 1 wherein the di-isocyanate is methylene bis(4-cyclohexyl isocyanate). 5. A polyurethane xerogel according to claim 1 wherein the diol is triethylene glycol (TEG). 6. A polyurethane xerogel according to claim 1 wherein the diol is diethylene glycol (DEG). 7. A polyurethane xerogel according to claim 1 wherein the diol is according to formula I and n is an integer from 2 to 10. 8. A polyurethane xerogel according to claim 1 wherein the diol is tetraethylene glycol (TTEG). 9. A polyurethane xerogel according to claim 1 wherein the polydialkyl siloxane diol is carbinol terminated. 10. A polyurethane xerogel according to claim 9 wherein the polydialkyl siloxane diol is of formula V, wherein R is alkyl, p is an integer from 1 to 110, and x is an integer from 1 to 324. 11. A polyurethane xerogel according to claim 10 wherein the polydialkyl siloxane diol of formula V is prepared by reacting a polydialkyl siloxane hydride terminated of formula III with an allyl polyglycol of formula IV 12. A polyurethane xerogel according to claim 9 wherein the polydialkyl siloxane diol is of Formula VI: wherein R represents a small alkyl group, Y represents an alkyl group, p is an integer from 1 to 110, x is an integer from 1 to 324, and A is an integer from 1 to 25. 13. A polyurethane xerogel according to claim 1 wherein the mixture further comprises one or more antioxidants. 14. A polyurethane xerogel according to claim 13 wherein the mixture comprises 1 to 3 wt % antioxidant. 15. A polyurethane xerogel according to claim 1 wherein the mixture further comprises a catalyst. 16. A polyurethane xerogel according to claim 15 wherein the catalyst is a transition metal catalyst, an amine or a polyamine. 17. A polyurethane xerogel according to claim 16 wherein the catalyst is selected from dibutyltin dilaurate, FeCl3, stannous octoate, and triethylamine. 18. A polyurethane xerogel according to claim 1 wherein the mixture further comprises one or more tinting agents. 19. A polyurethane xerogel according to claim 1 wherein the mixture further comprises one or more UV blockers. 20. A polyurethane xerogel according to claim 1 wherein the mixture further comprises one or more of a modulus modifier, a plasticizer, a humectant and a lubricant. 21. A polyurethane hydrogel comprising the polyurethane xerogel of claim 1 in hydrated form. 22. A process for preparing a polyurethane xerogel, said process comprising: (i) preparing a mixture comprising at least one polyethylene glycol having a molecular weight of 1,000 to 50,000, at least one di-isocyanate, at least one polydialkyl siloxane diol and at least one diol of formula I, wherein n is an integer from 1 to 10; and(ii) reacting the mixture formed in step (i) under substantially anhydrous conditions to form a polyurethane xerogel. 23. A polyurethane xerogel obtained by the process of claim 22. 24. A process for preparing a polyurethane hydrogel, said process comprising preparing a polyurethane xerogel according to claim 22, and hydrating said polyurethane xerogel with an aqueous medium to form a polyurethane hydrogel. 25. A polyurethane hydrogel obtained by the process of claim 24. 26. A contact lens comprising the polyurethane xerogel of claim 1. 27. A polyurethane xerogel according to claim 1, wherein n is an integer from 1 to 4. 28. A polyurethane xerogel prepared from a mixture comprising: (a) at least one polyethylene glycol having a molecular weight of 1,000 to 50,000;(b) at least one di-isocyanate;(c) at least one carbinol terminated polydialkyl siloxane diol; and(d) at least one diol of formula I wherein n is an integer from 1 to 25;wherein the polyethylene glycol, di-isocyanate, polydialkyl siloxane diol and diol are reacted under substantially anhydrous conditions. 29. A polymer according to claim 28 wherein the polydialkyl siloxane diol is of Formula VI: wherein R represents a small alkyl group, Y represents an alkyl group, p is an integer from 1 to 110, x is an integer from 1 to 324, and A is an integer from 1 to 25.
연구과제 타임라인
LOADING...
LOADING...
LOADING...
LOADING...
LOADING...
이 특허에 인용된 특허 (14)
Calvin Olin W. ; Schlagel Mark E. ; Keene Darren S. ; Kindt-Larsen Ture,DKX ; Walker Craig W. ; Martin Wallace A. ; Heaton John C., Automated method and apparatus for single sided hydration of soft contact lenses in package carriers.
Heifetz Aaron H. (Columbia MD) Wolfe Richard A. (Ellisville MO) Braatz James A. (Beltsville MD) Luthra Narender P. (Columbia MD), Cell growth enhancers and/or antibody production stimulators comprising chemically modified hydrophilic polyurea-urethan.
Braatz James A. (Rockville MD) Kehr Clifton L. (Silver Spring MD), Contact lenses based on biocompatible polyurethane and polyurea-urethane hydrated polymers.
Matthews Virgil Edison (Charleston WV) Knopf Robert John (Saint Albans WV), Lightly cross-linked polyurethane hydrogels based on poly(alkylene ether) polyols.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.