Method for reducing hyperdynamic facial wrinkles
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61B-018/02
A61B-018/00
출원번호
US-0325004
(2011-12-13)
등록번호
US-9039688
(2015-05-26)
발명자
/ 주소
Palmer, III, Francis R.
Hsu, Michael
Tatsutani, Kristine
출원인 / 주소
MyoScience, Inc.
대리인 / 주소
Kilpatrick Townsend and Stockton LLP
인용정보
피인용 횟수 :
6인용 특허 :
2
초록▼
A method for cryogenically treating a target tissue comprises providing a cryogenic device having one or more tissue penetrating needle probes, and advancing the one or more tissue penetrating needle probes through skin disposed above the target tissue into the target tissue. The target tissue compr
A method for cryogenically treating a target tissue comprises providing a cryogenic device having one or more tissue penetrating needle probes, and advancing the one or more tissue penetrating needle probes through skin disposed above the target tissue into the target tissue. The target tissue comprises a motor nerve. The method also includes cooling the target tissue with the one or more tissue penetrating needle probes, and temporarily disrupting signal conduction from the motor nerve thereby preventing contraction of a muscle operably coupled to the motor nerve. This reduces or eliminates hyperdynamic wrinkles of a patient's face.
대표청구항▼
1. A method for cryogenically treating a target tissue to reduce or eliminate hyperdynamic wrinkles of a face of a patient, said method comprising: providing a cryogenic device having one or more tissue penetrating needle probes;advancing the one or more tissue penetrating needle probes through skin
1. A method for cryogenically treating a target tissue to reduce or eliminate hyperdynamic wrinkles of a face of a patient, said method comprising: providing a cryogenic device having one or more tissue penetrating needle probes;advancing the one or more tissue penetrating needle probes through skin into the target tissue, the target tissue intersecting a motor nerve;providing a series of separate cooling treatments where the series of separate cooling treatments produce a treatment path along the target tissue to treat the motor nerve and to provide a continuous array of treated tissue in the face of the patient by: (1) cooling the target tissue with the one or more tissue penetrating needle probes at a first location;(2) retracting the one or more tissue penetrating needle probes after cooling the target tissue; and(3) positioning the one or more tissue penetrating needle probes such that cooling occurs at a subsequent location along the treatment path;(4) cooling the target tissue at the subsequent location such that the previously cooled target tissue and the subsequently cooled target tissue provide a continuous array of treated tissue in the face of the patient; andtemporarily disrupting signal conduction from the motor nerve with the series of separate cooling treatments thereby preventing contraction of a muscle operably coupled to the motor nerve; andreducing or eliminating hyperdynamic wrinkles of a patient's face. 2. The method of claim 1, wherein the one or more tissue penetrating needle probe comprises a multi-needle array. 3. The method of claim 1, further comprising identifying anatomical landmarks prior to advancing the one or more tissue penetrating needle through the skin and drawing a treatment line on a surface of the skin based on a position of the identified anatomical landmarks so as to provide a visual path for the series of separate cooling treatments along the treatment path. 4. The method of claim 3, wherein the anatomical landmarks are identified by palpation, the anatomical landmarks at least including an outer edge of a lateral orbital rim or a temporal ridge of the patient. 5. The method of claim 3, wherein the anatomical landmarks are identified by applying electrical stimulation, imaging, or locally injecting a substance. 6. The method of claim 3, further comprising applying a treatment template to the patient's face by aligning one or more alignment features of the treatment template with one or more of the identified anatomical landmarks of the patient's face, the treatment template providing a treatment guide for identifying a linear array of cooling treatment locations spaced apart from the one or more anatomical landmarks for guiding the series of separate cooling treatments and for facilitating the drawing of the treatment line on the surface of the skin. 7. The method of claim 1, wherein the one or more tissue penetrating needle probes are inserted substantially perpendicular to the target tissue. 8. The method of claim 1, wherein the one or more tissue penetrating needle probes are inserted substantially parallel to a surface of the skin. 9. The method of claim 1, wherein the target tissue comprises the angular nerve, and wherein the one or more tissue penetrating needle probes are inserted adjacent the frontomaxillary suture or the frontonasal suture. 10. The method of claim 1, wherein the target tissue comprises the angular nerve, and wherein the one or more tissue penetrating needle probes are inserted inferior or medial to the infraorbital foramen. 11. A method for cryogenically treating a target tissue to reduce or eliminate hyperdynamic wrinkles of a patient's face, said method comprising: providing a cryogenic device having one or more tissue penetrating needle probes;advancing the one or more tissue penetrating needle probes through skin at a first location and into the target tissue adjacent a lateral edge of an orbital rim of the patient's face, the target tissue intersecting a motor nerve;cooling the target tissue adjacent the lateral edge of the orbital rim of the patient's face with the one or more tissue penetrating needle probes;after cooling the target tissue adjacent the lateral edge of the orbital rim of the patient's face, positioning the one or more tissue penetrating probes at a second location adjacent to the target tissue that is posterior from the lateral edge of the orbital rim and between the lateral edge of the orbital rim and a hairline of the patient;cooling the target tissue at the second location with the one or more tissue penetrating needle probes such that the cooling treatment starts adjacent the lateral edge of an orbital rim on the patient's face and extends posteriorly toward the hairline of the patient's face; andreducing or eliminating hyperdynamic wrinkles of a patient's face. 12. A method for cryogenically treating a target tissue to reduce or eliminate hyperdynamic wrinkles of a patient's face, said method comprising: providing a cryogenic device having one or more tissue penetrating needle probes;advancing the one or more tissue penetrating needle probes through skin at a first location and into the target tissue adjacent the tragus, the target tissue intersecting a motor nerve;cooling the target tissue adjacent the tragus with the one or more tissue penetrating needle probes;after cooling the target tissue adjacent the tragus, positioning the one or more tissue penetrating probes at a second location adjacent to the target tissue that is anterior to the first location along a zygomatic arch;cooling the target tissue at the second location with the one or more tissue penetrating needle probes such that the cooling treatment starts adjacent the tragus and progresses anteriorly along the zygomatic arch of the patient's face; andreducing or eliminating hyperdynamic wrinkles of a patient's face. 13. The method of claim 1, wherein the disruption comprises Wallerian degeneration of the motor nerve. 14. The method of claim 1, wherein a temporal branch of the motor nerve adjacent an orbital rim is temporarily disrupted. 15. The method of claim 1, further comprising protecting the skin disposed above the target tissue from cooling induced injury. 16. The method of claim 15, wherein protecting comprises heating the skin disposed above the target tissue. 17. The method of claim 1, further comprising locally anesthetizing a portion of a patient's face. 18. A method for cryogenically treating a target tissue, said method comprising: providing a cryogenic device having one or more tissue penetrating needle probes;providing a treatment template having an alignment feature corresponding to an anatomical landmark on a face of a patient and a treatment guide configured to indicate a treatment path spaced apart from the anatomical landmark on the face of the patient that is associated with the alignment feature;aligning the treatment template on a temple region of the face of the patient by aligning the alignment feature of the treatment template with the corresponding anatomical landmark on the face of the patient;maintaining the treatment template on the temple region and drawing the treatment path on a surface of the skin as indicated by the treatment guide;advancing along the drawn treatment path the one or more tissue penetrating needle probes into the target tissue, the target tissue intersecting a motor nerve;cooling the target tissue along the treatment path with the one or more tissue penetrating needle probes so as to provide a continuous array of treated tissue in the face of the patient;temporarily disrupting signal conduction from the motor nerve thereby preventing contraction of a muscle operably coupled to the motor nerve; andreducing or eliminating hyperdynamic wrinkles of a patient's face. 19. The method of claim of claim 18, wherein the alignment feature comprises a first corner of the treatment template, wherein a bottom edge of the treatment template leads from the first corner of the treatment template, and wherein a side edge of the treatment template leads from the first corner of the treatment template to a second corner of the treatment template in a direction perpendicular to the bottom edge. 20. The method of claim 19, wherein the anatomical landmark corresponding to the alignment feature comprises a lateral canthus of the temple region, and wherein aligning the treatment template comprises placing the first corner of the treatment template at the lateral canthus on the temple region. 21. The method of claim 20, wherein aligning the treatment template further comprises aligning the bottom edge in an anterior to posterior direction such that the bottom edge extends in the posterior direction from the first corner of the treatment template. 22. The method of claim 20, wherein the treatment guide extends from the second corner at an angle of approximately 30 degrees with respect to the bottom edge of the treatment template so as to identify a linear array of treatment locations from the lateral canthus region to the hairline of the user when aligned on the temple region of the face of the patient. 23. The method of claim of claim 18, wherein the treatment template comprises a flexible transparent plastic sheet. 24. The method of claim of claim 18, wherein the treatment template comprises an adhesive tape. 25. The method of claim of claim 24, wherein the adhesive tape includes a medication. 26. The method of claim of claim 24, wherein the treatment template includes a heating element configured to heat a region of skin along the treatment guide of the treatment template. 27. The method of claim 26, further comprising heating the skin during cooling using the heating element of the treatment template. 28. A template for cryogenically treating a target tissue, the template comprising: a planar body having an alignment feature for aligning the planar body with a lateral canthus on a temple region of a face, the temple region having target tissue;a treatment guide being configured to identify a linear array of treatment locations relative to the lateral canthus on the temple region of the to provide a continuous array of treated tissue in the face of the patient with the cryogenic treatment, the identified linear array of treatment locations providing a guide for one or more tissue penetrating needle probes to advance through skin into the target tissue, the target tissue intersecting a motor nerve. 29. The template of claim 28, wherein the alignment feature comprises a first corner, wherein a bottom edge leads from the first corner, and wherein a side edge leads from the first corner to a second corner in a direction perpendicular to the bottom edge. 30. The template of claim 29, wherein the treatment guide extends from the second corner at an angle of approximately 30 degrees with respect to the bottom edge of the treatment template so as to identify the linear array of treatment locations from the lateral canthus region to the hairline of the user when aligned on the temple region of the face of the patient. 31. The template of claim of claim 28, wherein the planar body comprises a flexible transparent plastic sheet. 32. The template of claim of claim 28, wherein the planar body comprises adhesive tape. 33. The template of claim of claim 32, wherein the adhesive tape includes a medication. 34. The template of claim of claim 32, further comprising a heating element configured to heat a region along the treatment guide. 35. The method of claim 1, wherein providing the series of separate cooling treatments further comprises: (5) checking an effect of the cooling treatment; and (6) repeating steps (2)-(5) until a desired effect is achieved. 36. The method of claim 1, wherein providing the series of separate cooling treatments further comprises: (5) repeating steps (2)-(4) until the series of separate cooling treatments reaches a hairline of the patient. 37. The method of claim 1, wherein the series of separate cooling treatments progresses in an anterior to posterior direction along the target tissue. 38. The method of claim 37, wherein the series of separate cooling treatments progresses in the anterior to posterior direction toward a hairline of the patient. 39. The method of claim 1, wherein the series of separate cooling treatments progresses in a posterior to anterior direction along the target tissue. 40. The method of claim 6, further comprising activating a heating element of the treatment template to heat the skin of the patient adjacent the linear array of cooling treatment locations, and wherein the heating element is coupled with a battery, and wherein activating the heating element of the treatment template comprises delivering power from the battery to the heating element. 41. The method of claim 27, wherein the heating element of the treatment template is coupled with a battery, and wherein heating the skin during cooling using the heating element of the treatment template comprises delivering power from the battery to the heating element. 42. The template of claim 34, wherein the heating element is coupled with a battery.
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