Filamentary devices for treatment of vascular defects
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61M-029/00
A61B-017/12
A61M-029/02
A61B-017/00
A61B-018/00
출원번호
US-0911034
(2010-10-25)
등록번호
US-9039726
(2015-05-26)
발명자
/ 주소
Becking, Frank P.
출원인 / 주소
Covidien LP
대리인 / 주소
O'Brien, Esq., Elizabeth A.
인용정보
피인용 횟수 :
2인용 특허 :
211
초록▼
Braid-balls suitable for aneurysm occlusion and/or parent vessel occlusion/sacrifice (e.g., in treating neurovascular defects) are disclosed. Especially for aneurysm treatment, but also for either one of the aforementioned treatments, the form of the ball is very important. In particular, the densit
Braid-balls suitable for aneurysm occlusion and/or parent vessel occlusion/sacrifice (e.g., in treating neurovascular defects) are disclosed. Especially for aneurysm treatment, but also for either one of the aforementioned treatments, the form of the ball is very important. In particular, the density of the device is paramount in applications where braid itself is intended to moderate or stop blood flow—allowing thrombosis within a volume formed by the ball.
대표청구항▼
1. A device for treatment of a patient's vasculature, comprising: a self-expanding resilient permeable shell having a proximal portion, a distal portion, a longitudinal axis and further comprising: a plurality of elongate resilient filaments with a woven structure secured relative to each other at t
1. A device for treatment of a patient's vasculature, comprising: a self-expanding resilient permeable shell having a proximal portion, a distal portion, a longitudinal axis and further comprising: a plurality of elongate resilient filaments with a woven structure secured relative to each other at the proximal and distal portions thereof, the filaments (i) radially converging to a first cross-section at each of the proximal and distal portions to form respective proximal and distal filament tufts, and (ii) radially diverging from the first cross-section to a second cross-section, larger than the first cross-section, such that free ends of the filaments flare outwardly within the shell for promoting thrombosis of blood;a radially constrained elongated state configured for delivery within a microcatheter with the thin woven filaments extending longitudinally from the proximal portion to the distal portion radially adjacent each other along a length of the filaments; andan expanded relaxed state with a globular and longitudinally shortened configuration relative to the radially constrained state with the woven filaments forming the self-expanding resilient permeable shell in a smooth path radially expanded from the longitudinal axis between the proximal portion and distal portion including a plurality of openings in the shell formed between the woven filaments, the largest of said openings being configured to allow blood flow through the openings at a velocity below a thrombotic threshold velocity. 2. The device of claim 1, wherein at least the shell distal portion includes a bend in a recessed configuration such that the distal filament tuft is disposed axially within a nominal contour of the permeable shell structure in the expanded state. 3. The device of claim 2, wherein the proximal portion of the shell further comprises a bend in a recessed configuration such that the proximal filament tuft is withdrawn axially within the nominal permeable shell. 4. The device of claim 1, wherein the filaments of the permeable shell are secured relative to each other in wraps or bands. 5. The device of claim 1, further comprising a distal hub secured to the distal filament tuft. 6. The device of claim 1, further comprising a proximal hub secured to the proximal filament tuft. 7. The device of claim 1, further comprising a band forming a cavity for a detachment tether. 8. The device of claim 7, further comprising a detachment tether secured through the cavity of the proximal hub. 9. The device of claim 1, wherein the filaments of the permeable shell have a transverse dimension of about 0.001 inch to about 0.003 inch. 10. The device of claim 1, wherein the permeable shell comprises at least about 72 filaments. 11. The device of claim 1, wherein the filaments of the permeable shell comprise a superelastic material. 12. The device of claim 11, wherein the superelastic material comprises a shape memory metal. 13. The device of claim 1, wherein the filaments of the permeable shell comprise a shape memory material that is heat set in a configuration of the relaxed expanded state. 14. The device of claim 13, wherein the shape memory metal comprises a NiTi alloy. 15. The device of claim 1, wherein the largest openings formed between adjacent filaments of a defect spanning portion of the permeable shell are about 0.017 inches to about 0.032 inches. 16. A delivery system for deployment of a device for treatment of a patient's vasculature, comprising: a microcatheter having an inner lumen extending a length thereof;a device for treatment of a patient's vasculature disposed within the inner lumen of the microcatheter and comprising a self-expanding resilient permeable shell of thin filaments, the permeable shell having a proximal portion, a distal portion, a longitudinal axis, a radially constrained elongated state, and an expanded state;wherein in the constrained state, the device is configured for delivery within a microcatheter with the thin woven filaments extending longitudinally from the proximal portion to the distal portion radially adjacent each other, andwherein in the expanded state, the filaments of the proximal and distal portions (i) radially converge to a first cross-section at each of the proximal and distal portions to form respective proximal and distal filament tufts, and (ii) radially diverge from the first cross-section to a second cross-section, larger than the first cross-section, such that free ends of the filaments flare outwardly within the shell for promoting thrombosis of blood, the device having, in the expanded state, a globular and axially shortened configuration relative to the constrained state with the woven filaments forming the self-expanding resilient permeable shell in a smooth path radially expanded from the longitudinal axis between the proximal portion and distal portion and a plurality of openings in the shell formed between the woven filaments, the permeable shell further having a portion when in the expanded relaxed state that is configured to span an opening of a patient's vascular defect; andan elongate delivery apparatus having a proximal end and a distal end releasably secured to a proximal hub of the device. 17. The system of claim 16, wherein at least the shell distal portion includes a bend in a recessed configuration such that the distal filament tuft is disposed axially within a nominal contour of the permeable shell structure in the expanded state. 18. The system of claim 17, wherein the proximal portion of the shell further comprises a bend in a recessed configuration such that the proximal filament tuft is disposed axially within the nominal contour of the permeable shell structure in the expanded state. 19. The system of claim 16, wherein the filaments of the permeable shell are secured relative to each other in wraps or bands. 20. The system of claim 16, wherein the device comprises a distal hub secured to the distal filament tuft. 21. The system of claim 16, wherein the device comprises a proximal hub secured to the proximal filament tuft.
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