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Kafe 바로가기국가/구분 | United States(US) Patent 등록 |
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국제특허분류(IPC7판) |
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출원번호 | US-0787331 (2013-03-06) |
등록번호 | US-9042965 (2015-05-26) |
발명자 / 주소 |
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출원인 / 주소 |
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인용정보 | 피인용 횟수 : 1 인용 특허 : 401 |
An intracorporeal marker, for marking a site within living tissue of a host, includes an outer body portion of biodegradable material. An inner body portion is located in the outer body portion. The inner body portion includes biological material that becomes calcified in the living tissue of the ho
An intracorporeal marker, for marking a site within living tissue of a host, includes an outer body portion of biodegradable material. An inner body portion is located in the outer body portion. The inner body portion includes biological material that becomes calcified in the living tissue of the host over time. An agent interacts with the biological material to promote calcification of the biological material of the inner body portion in the living tissue of the host.
1. An intracorporeal marker for marking a site within living tissue of a host, the intracorporeal marker comprising: an outer body portion of biodegradable material;an inner body portion located in the outer body portion, the inner body portion configured to include elastin that becomes calcified in
1. An intracorporeal marker for marking a site within living tissue of a host, the intracorporeal marker comprising: an outer body portion of biodegradable material;an inner body portion located in the outer body portion, the inner body portion configured to include elastin that becomes calcified in the living tissue of the host over time; andan agent configured to interact with the elastin to promote calcification of the elastin of the inner body portion in the living tissue of the host, wherein the agent is selected from a group consisting of bone growth factor, phospholipids, and polyethylene glycol. 2. The marker of claim 1, wherein the biological material inner body portion includes porcine aortic wall tissue. 3. The marker of claim 1, wherein the elastin has been cross-linked. 4. The marker of claim 1, wherein the inner body portion is entirely encased within the outer body portion, and the outer body portion is porous. 5. The marker of claim 1, wherein the outer body portion includes collagen. 6. The marker of claim 1, wherein the outer body portion is a porous gelatin. 7. An intracorporeal marker for marking a site within living tissue of a host, the intracorporeal marker comprising: an outer body portion of biodegradable material configured to be ultrasound detectable;an inner body portion located in the outer body portion, the inner body portion including elastin configured to calcify in the living tissue of the host over a period of time to enhance X-ray or MRI detectability of the inner body portion; andan agent configured to interact with the elastin to promote calcification of the elastin of the inner body portion in the living tissue of the host, wherein the agent is selected from a group consisting of bone growth factor, phospholipids, and polyethylene glycol. 8. The marker of claim 6, wherein the outer body portion is configured to be detectable by ultrasound over a first time period and the inner body portion is configured to undergo calcification to be detectable by X-ray or MRI prior to the expiration of the first time period. 9. The marker of claim 7, wherein the inner body portion is entirely encased within the outer body portion, and the outer body portion is porous. 10. The marker of claim 7, wherein the with elastin has been cross-linked. 11. The marker of claim 7, wherein the inner body portion includes porcine aortic wall tissue. 12. The marker of claim 7, wherein the outer body portion includes porous collagen. 13. The marker of claim 7, wherein the outer body portion is a porous gelatin. 14. An intracorporeal marker for marking a site within living tissue of a human host, the intracorporeal marker comprising: an outer body portion of biodegradable material;an inner body portion located within the outer body portion, the inner body portion including elastin configured to calcify in the living tissue of the human host over time; andan additive that interacts with the elastin to promote calcification of the elastin in the living tissue of the human host, wherein the additive is selected from a group consisting of bone growth factor, phospholipids, and polyethylene glycol. 15. The marker of claim 14, wherein the inner body portion is entirely encased within the outer body portion, and the outer body portion is porous. 16. The marker of claim 14, wherein the biodegradable material of the outer body portion of is one of collagen foam or gelatin foam, and the elastin is embedded in the outer body portion.
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