Systems and methods for reshaping an eye feature
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61B-018/18
A61F-009/013
A61F-009/008
출원번호
US-0480127
(2012-05-24)
등록번호
US-9044308
(2015-06-02)
발명자
/ 주소
Muller, David
Thompson, Vance
출원인 / 주소
Avedro, Inc.
대리인 / 주소
McDonnell Boehnen Hulbert & Berghoff LLP
인용정보
피인용 횟수 :
0인용 특허 :
80
초록▼
Systems and methods include a cutting instrument that creates incisions in selected areas of the cornea; an eye therapy system that applies reshaping forces to the cornea; and a controller that determines the selected areas of the cornea for the incisions and the reshaping forces from the eye therap
Systems and methods include a cutting instrument that creates incisions in selected areas of the cornea; an eye therapy system that applies reshaping forces to the cornea; and a controller that determines the selected areas of the cornea for the incisions and the reshaping forces from the eye therapy system, such that the reshaping forces and the incisions combine to achieve corrective reshaping of the cornea. Other systems and methods include measuring an eye to determine a required amount of reshaping of a cornea; determining one or more doses of cross-linking agent and one or more corresponding doses of photoactivating light according to the required amount of reshaping; applying the cross-linking agent to the cornea; and delivering, from a light source, the photoactivating light to the area of the eye, the photoactivating light combining with the cross-linking agent to induce the corrective reshaping of the cornea.
대표청구항▼
1. A system for treating an eye, comprising: a first eye treatment system configured to apply reshaping forces to a cornea;a second eye treatment system including a cutting instrument configured to form secondary incisions in selected regions of the cornea along layers of collagen fibrils in the sel
1. A system for treating an eye, comprising: a first eye treatment system configured to apply reshaping forces to a cornea;a second eye treatment system including a cutting instrument configured to form secondary incisions in selected regions of the cornea along layers of collagen fibrils in the selected regions to form slip planes parallel to a surface of the cornea that relieve stresses resulting from intraocular pressure associated with the reshaping forces applied by the first eye treatment system; anda controller configured to determine the selected regions of the cornea for the secondary incisions formed by the cutting instrument of the second eye treatment system based on the reshaping forces applied by the first eye treatment system, the secondary incisions relieving the stresses associated with the reshaping forces, the reshaping forces and the secondary incisions combining to achieve a predetermined corrective reshaping of the cornea. 2. The system of claim 1, wherein the cutting instrument includes a femtosecond laser. 3. The system of claim 1, wherein the first eye treatment system includes a LASIK surgery system, the LASIK surgery system including a microkeratome that cuts a flap in the cornea and an excimer laser that ablates corneal tissue to apply the reshaping forces, the microkeratome and the excimer laser acting separately from the cutting instrument of the second eye treatment system, the secondary incisions formed by the cutting instrument being separate from the results of the actions of the microkeratome and the excimer laser. 4. The system of claim 1, wherein the first eye treatment system includes a thermokeratoplasty system, the thermokeratoplasty system including an applicator that applies energy to shrink corneal tissue and apply the reshaping forces. 5. The system of claim 1, wherein the first eye treatment system includes a cross-linking treatment system, the cross-linking treatment system including an applicator that applies a cross-linking agent to the cornea and a light source that provides photoactivating light for the cross-linking agent, the photoactivating light acting on the cross-linking agent initiating cross-linking activity in the selected regions to apply the reshaping forces. 6. The system of claim 5, wherein the cross-linking treatment system further comprises optical elements that direct the photoactivating light to the selected regions of the cornea with the applied cross-linking agent. 7. The system of claim 1, wherein the selected regions of the cornea for the secondary incisions determined by the controller include regions of posterior corneal tissue to relieve stress associated with the reshaping forces applied to the anterior corneal tissue. 8. A method for treating an eye, comprising: applying, with a first eye treatment system, reshaping forces to a cornea;forming, with a cutting instrument of a second eye treatment, secondary incisions in selected regions of the cornea along layers of collagen fibrils in the selected regions to form slip planes parallel to a surface of the cornea that relieve stresses resulting from intraocular pressure associated with the reshaping forces applied by the first eye treatment system; anddetermining the selected regions of the cornea for the secondary incisions formed by the cutting instrument of the second eye treatment based on the reshaping forces applied by the first eye treatment system, the secondary incisions relieving the stresses associated with the reshaping forces, the reshaping forces and the secondary incisions combining to achieve a predetermined corrective reshaping of the cornea. 9. The method of claim 8 wherein the cutting instrument includes a femtosecond laser. 10. The method of claim 8 wherein the first eye treatment system includes a LASIK surgery system, the LASIK surgery system including a microkeratome and an excimer laser, wherein applying the reshaping forces includes ablating corneal tissue with the excimer laser after creating a corneal flap with the microkerotome, the microkeratome and the excimer laser acting separately from the cutting instrument of the second eye treatment system, the secondary incisions formed by the cutting instrument being separate from the results of the actions of the microkeratome and the excimer laser. 11. The method of claim 8 wherein the first eye treatment system includes a thermokeratoplasty system, the thermokeratoplasty system including an applicator, wherein applying the reshaping forces includes applying energy with the applicator to shrink corneal tissue. 12. The method of claim 8 wherein the first eye treatment system includes a cross-linking treatment system, the cross-linking treatment system including an applicator that applies a cross-linking agent to the cornea and a light source that provides photoactivating light for the cross-linking agent wherein applying the reshaping forces includes applying the cross-linking agent and directing the photoactivating light to the cross-linking agent in the selected regions to initiate cross-linking activity. 13. The method of claim 12 wherein the cross-linking treatment system further comprises optical elements that direct the photoactivating light to the selected regions of the cornea with the applied cross-linking agent. 14. The method of claim 8 wherein forming the secondary incisions includes forming the secondary incisions in posterior corneal tissue to relieve stress associated with the reshaping forces applied to the anterior corneal tissue. 15. A method for treating an eye, comprising: applying a first treatment to an eye, the first treatment resulting in a requirement for post-procedural refractive correction of the cornea;determining an amount of the refractive correction of the cornea to be achieved by cross-linking after the first treatment applied to the eye;determining one or more doses of cross-linking agent and one or more corresponding doses of photoactivating light according to the determined amount of refractive correction of the cornea;applying the one or more doses of cross-linking agent to the cornea; anddelivering, from a light source, the one or more doses of photoactivating light to the eye, the one or more doses of photoactivating light combining with the one or more doses of cross-linking agent to induce the determined amount of refractive correction of the cornea, the determined amount refractive correction of the cornea being induced without assistance of a mold applied to the eye during the delivery of the one or more doses of photoactivating light to the eye. 16. The method of claim 15 wherein the cross-linking agent includes Riboflavin, and the one or more doses of photoactivating light includes a dose of ultraviolet light greater than 5.4 J/cm2. 17. The method of claim 15 wherein applying the first treatment to the eye includes conducting cataract surgery on the eye, the cataract surgery resulting in a residual myopia that requires the refractive correction of the cornea. 18. The method of claim 15 wherein applying the first treatment to the eye includes conducting LASIK surgery on the cornea, the LASIK surgery requiring additional reshaping of the cornea to achieve a desired corneal shape. 19. The method of claim 15 wherein applying the first treatment to the eye includes applying thermokeratoplasty to the cornea, the thermokeratoplasty requiring additional reshaping of the cornea to achieve a desired corneal shape. 20. The system of claim 1, wherein the secondary incisions at least partially disassociate or separate anterior corneal tissue from posterior corneal tissue in one or more of the selected regions. 21. The system of claim 1, wherein the second eye treatment system is configured to form the secondary incisions without ablation. 22. The method of claim 8, wherein the secondary incisions at least partially disassociate or separate anterior corneal tissue from posterior corneal tissue in one or more of the selected regions. 23. The method of claim 8, wherein the secondary incisions are formed after applying the first eye treatment system to reshape the cornea.
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