Comfortable ophthalmic device and methods of its production
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
G02C-007/04
A61L-027/34
A61L-027/50
A61L-027/54
B29D-011/00
G02B-001/04
A61L-012/04
출원번호
US-0836133
(2013-03-15)
등록번호
US-9052529
(2015-06-09)
발명자
/ 주소
McCabe, Kevin P.
Steffen, Robert B.
Aguilar, Hélène
Martin, W. Anthony
Neadle, Susan W.
Meyers, Ann-Marie W.
Vanderlaan, Douglas G.
Gourd, Dominic P.
Canavan, Kristy L.
Hill, Gregory A.
출원인 / 주소
Johnson & Johnson Vision Care, Inc.
대리인 / 주소
Harding, Karen A.
인용정보
피인용 횟수 :
0인용 특허 :
138
초록
This invention relates to comfortable ophthalmic devices and methods of producing such devices. The ophthalmic devices are contacted with a polyamide wetting agent and heated to a temperature of at least about 50° C. to about 150° C.
대표청구항▼
1. A method of producing an ophthalmic lens comprising, treating a polymerized ophthalmic lens that does not comprise a wetting agent prior to its polymerization with about 350 to about 1000 ppm wetting agent having a number average molecular weight of about 400,000 or greater, a polydispersity of l
1. A method of producing an ophthalmic lens comprising, treating a polymerized ophthalmic lens that does not comprise a wetting agent prior to its polymerization with about 350 to about 1000 ppm wetting agent having a number average molecular weight of about 400,000 or greater, a polydispersity of less than about 2 and selected from the group consisting of poly(N,N-dimethylacrylamide), poly(N-methylacrylamide), poly(N-2-hydroxyethylmethacrylamide), and poly(glucosamineacrylamide)], and mixtures thereof, and heating said lens to a temperature of at least about 50° C. to about 150° C. 2. The method of claim 1 wherein treating comprises heating the polymerized ophthalmic lens and wetting agent in a packaging solution. 3. The method of claim 2 wherein the packaging solution comprises deionized water, or saline solution. 4. The method of claim 2 wherein the packaging solution comprises a borate buffer or a phosphate buffer. 5. The method of claim 1 wherein the wetting agent comprises poly(N-2-hydroxyethylmethacrylamide). 6. The method of claim 1 wherein said wetting agent is water soluble polymer and has a number average molecular weight of 500,000 to about 3,000,000. 7. The method of claim 6 wherein said wetting agent has a polydispersity of between about 1 and about 2. 8. The method of claim 1 wherein treating comprises heating the polymerized ophthalmic lens in a packaging solution at a temperature of greater than about 80° C. 9. The method of claim 1 wherein treating comprises heating the polymerized ophthalmic lens in a packaging solution comprising at a temperature of greater than about 120C to about 150° C. 10. The method of claim 6 wherein the treating step is conducted in an individual sealed contact lens package. 11. The method of claim 1 wherein the treating step is conducted in an individual sealed contact lens package. 12. The method of claim 6 wherein the ophthalmic lens is selected from the group consisting of acofilcon A, alofilcon A, alphafilcon A, amifilcon A, astifilcon A, atalafilcon A, balafilcon A, bisfilcon A, bufilcon A, comfilcon, crofilcon A, cyclofilcon A, darfilcon A, deltafilcon A, deltafilcon B, dimefilcon A, drooxifilcon A, epsifilcon A, esterifilcon A, etafilcon A, focofilcon A, genfilcon A, govafilcon A, hefilcon A, hefilcon B, hefilcon D, hilafilcon A, hilafilcon B, hioxifilcon B, hioxifilcon C, hixoifilcon A, hydrofilcon A, lenefilcon A, licryfilcon A, licryfilcon B, lidofilcon A, lidofilcon B, lotrafilcon A, lotrafilcon B, mafilcon A, mesifilcon A, methafilcon B, mipafilcon A, nelfilcon A, netrafilcon A, ocufilcon A, ocufilcon B, ocufilcon C, ocufilcon D, ocufilcon E, ofilcon A, omafilcon A, oxyfilcon A, pentafilcon A, perfilcon A, pevafilcon A, phemfilcon A, polymacon, silafilcon A, siloxyfilcon A, tefilcon A, tetrafilcon A, trifilcon A, and xylofilcon A. 13. The method of claim 6 wherein the ophthalmic lens is selected from the group consisting of genfilcon A, lenefilcon A, lotrafilcon A, lotrafilcon B, balafilcon A, comfilcon, etafilcon A, nelfilcon A, hilafilcon, and polymacon. 14. The method of claim 6 wherein the ophthalmic lens is selected from the group consisting of genfilcon A, lenefilcon A, etafilcon A, nelfilcon A, hilafilcon, and polymacon. 15. The method of claim 6 wherein the ophthalmic lens is selected from the group consisting of etafilcon A, nelfilcon A, hilafilcon, and polymacon. 16. The method of claim 1 wherein the ophthalmic lens is selected from the group consisting of etafilcon A, nelfilcon A, hilafilcon, and polymacon. 17. The method of claim 6 wherein the ophthalmic lens is selected from the group consisting of etafilcon A. 18. The method of claim 1 wherein the ophthalmic lens is selected from the group consisting of etafilcon A. 19. The method of claim 6 wherein the polymerized ophthalmic lens is an un-hydrated polymerized ophthalmic lens. 20. The method of claim 19 wherein treating comprises contacting the un-hydrated polymerized ophthalmic lens with a packaging solution comprising a borate buffer or a phosphate buffer. 21. The method of claim 20 wherein the treating further comprises heating the un-hydrated polymerized ophthalmic lens and the packaging solution to a temperature of at least about 50° C. to about 100° C. 22. The method of claim 20 wherein the treating further comprises maintaining the un-hydrated polymerized ophthalmic lens and the packaging solution at a temperature of at least about 10° C. to about room temperature. 23. An ocular device comprising a polymerized ophthalmic lens wherein said polymerized ophthalmic lens does not comprise a wetting agent prior to its polymerization, and is treated with about 350 to about 1000 ppm wetting agent, having a number average molecular weight of about 400,000 or greater, a polydispersity of less than about 2 and selected from the group consisting of poly(N,N-dimethylacrylamide), poly(N-methylacrylamide), poly(N-2-hydroxyethylmethacrylamide), and poly(glucosamineacrylamide)], and mixtures thereof. 24. The method of claim 23 wherein the wetting agent comprises poly(N-2-hydroxyethylmethacrylamide). 25. The device of claim 23 wherein said device does not distort the user's vision. 26. The device of claim 23 wherein said wetting agent remains in the ophthalmic lens after about 6 hours to about 24 hours of wear by a user. 27. The method of claim 1, 14 or 15 wherein the wetting agent comprises poly(N,N-dimethyl acrylamide).
연구과제 타임라인
LOADING...
LOADING...
LOADING...
LOADING...
LOADING...
이 특허에 인용된 특허 (138)
Hirt Thomas ; Lohmann Dieter,CHX ; Hopken Jens,DEX ; Liu Qin, Amphiphilic, segmented copolymer of controlled morphology and ophthalmic devices including contact lenses made therefrom.
Abrams Richard W. (Jacksonville FL) Hutchinson Ben A. (Atlantic Beach FL) Maroukis David M. (Huntersville NC) Monsees Claude E. (Fort Mill SC), Apparatus and method for sterilization and secondary packaging.
Abrams Richard W. (Jacksonville FL) Matsumoto Hiroshi (Saitama-Pref. JPX) Wang Daniel T. (Jacksonville FL) Pricer Kenneth K. (Switzerland FL), Apparatus and method for sterilization and secondary packaging.
McCabe, Kevin P.; Molock, Frank F.; Hill, Gregory A.; Alli, Azaam; Steffen, Robert B.; Vanderlaan, Douglas G.; Young, Kent A., Biomedical devices containing internal wetting agents.
Heiler David J. (Avon NY) Marsh David A. (Rochester NY) Jonasse Matthew S. (Sodus NY) Panicucci Rick (Rochester NY), Cleaning hydrophilic contact lenses by electrochemical means.
Sherman Guy J. (St. Tammany LA), Cleaning, conditioning, storing and wetting system and method for rigid gas permeable contact lenses and other contact l.
McCabe, Kevin P.; Steffen, Robert B.; Aguilar, Helene; Martin, W. Anthony; Neadle, Susan W.; Meyers, Ann-Marie W.; Gourd, Dominic P.; Canavan, Kristy L.; Hill, Gregory A.; Vanderlaan, Douglas G., Comfortable ophthalmic device and methods of its production.
McCabe, Kevin P.; Steffen, Robert B.; Aguilar, Helene; Martin, W. Anthony; Neadle, Susan W.; Meyers, Ann-Marie W.; Vanderlaan, Douglas G.; Gourd, Dominic P.; Canavan, Kristy L.; Hill, Gregory A., Comfortable ophthalmic device and methods of its production.
Dziabo Anthony J. (El Toro CA) Karageozian Hampar (Laguna Hills CA) Ripley Paul S. (Irvine CA) Lam Sam W. (Laguna Niguel CA) Espiritu J. Abraham (Oceanside CA), Compositions and methods to clean contact lenses.
Sanka Ravi Sankar (Jacksonville FL) Wang Daniel Tsu-Fang (Jacksonville FL) Abrams Richard Wayne (Jacksonville FL) Lepper John Mark (Jacksonville FL) Martin Wallace Anthony (Orange Park FL) Walker Cra, Computer system for quality control correlations.
Zhang Hong J. ; Ellis Edward J. ; Wrobel Stanley J. ; Potini Chimpiramma, Contact lens cleaning and wetting solutions containing a non-amine polyethyleneocy adduct having a HLB value of at leas.
Seiderman Maurice (3306 Deronda Drive Hollywood CA 90028), Contact lens from hydrophilic gel polymers of polyvinylpyrrolidone and hydroxyalkyl methacrylate.
Annie C. Maiden ; Douglas G. Vanderlaan ; David C. Turner ; Robert N. Love ; James D. Ford ; Frank F. Molock ; Robert B. Steffen ; Gregory A. Hill ; Azaam Alli ; Kevin P. McCabe, Hydrogel with internal wetting agent.
Gyulai Peter (Santa Ana CA) Thomas Larry K. (Fullerton CA) Osterwald Hermann (Bovenden-Eddigehausen DEX), Hydrogen peroxide destroying compositions and methods of making and using same.
Geyer Otto-Christian (Wetzlar DEX) Wingler Frank (Leverkusen DEX), Hydrophilic copolymers, the use thereof as biomedical materials and contact-optical articles produced therefrom.
Bambury Ronald E. (63 Matthew Dr. Fairport NY 14450) Choo Dong J. (Department of Chemistry ; Kyung-Hee University Dongdaemun-ku ; Seoul ; 131 KRX), Hydrophilic oxygen permeable polymers.
Li, Hongwen; Ruscio, Dominic V.; Lai, Yu Chin; Huang, Horngyih, Lens molds with protective coatings for production of contact lenses and other ophthalmic products.
Byram David Clarence ; Duncan Gregory Scott ; Mills Marlaine Gail ; Peck James Malcolm ; Pricer Kenneth Kurt, Method and support for supporting packages only at their edges during steam sterilization.
Heiler David J. (Avon NY) Jonasse Matthew S. (Sodus NY) Marsh David A. (Rochester NY) Rogalskyj Jill S. (Livonia NY), Method for indicating neutralization of contact lens disinfecting solutions.
Wajs Georges (Ivry FR) Lenne William (Gagny FR), Method for preparing a crosslinked graft copolymer of silicone and polyvinylpyrrolidone for use as a contact lens, and a.
Huth Stanley W. (Newport Beach CA) Lam Sam W. (Irvine CA) Kiral Richard M. (Irvine CA), Method for the simultaneous cleaning and disinfecting of contact lenses.
Holly Frank J. (301 York Ave. Lubbock TX 79416) Tonge Stephen R. (Birmingham GB2), Method for using an antimicrobial agent for ophthalmic formulations.
Kindt-Larsen Ture (Vedbaek FL DKX) Heaton John C. (Jacksonville FL) Rastrelli Edmund C. (Jacksonville FL), Method of forming shaped hydrogel articles including contact lenses.
Kindt-Larsen Ture (Vedbaek FL DKX) Heaton John C. (Jacksonville FL) Rastrelli Edmund C. (Jacksonville FL) Hill Gregory A. (Jacksonville FL), Method of forming shaped hydrogel articles including contact lenses.
Huth Stanley W. (Newport Beach CA) Lam Sam W. (Laguna Niguel CA) Espiritu Abraham M. (Oceanside CA), Non-oxidative method and composition for simultaneously cleaning and disinfecting contact lenses using a protease with a.
Abrams Richard (Jacksonville FL) Edwards Russell J. (Jacksonville FL) Ebel James A. (Jacksonville FL) Keene Darren S. (Jacksonville FL), Ophthalmic lens package.
Troy Vernon Holland ; Thomas Hirt CH; Jacalyn Mary Schremmer ; Richard Carlton Baron ; Wilson Leonard Terry, Jr. ; Aaldert Rens Molenberg CH, Organic polymers.
Lust Victor ; Abrams Richard Wayne ; Beaton Stephen Robert ; Renkema Kornelis ; van der Meulen Wybren,NLX ; Wu Jongliang ; Wang Daniel Tsu-Fang, Packaging arrangement for contact lenses.
Wu Jongliang ; Wang Daniel Tsu-Fang ; Beaton Stephen Robert ; Renkema Kornelis ; Van Der Meulen Wybren ; Lust Victor ; Abrams Richard Wayne, Packaging arrangement for contact lenses.
Sherman Guy J. (Mandeville LA), Preservative system for ophthalmic and contact lens solutions and method for cleaning disinfecting and storing contact l.
Wu Chi-San (Wayne NJ) Curry James F. (Wayne NJ) Cullen James P. (Bartonsville PA), Process for making narrow molecular weight distribution polyvinylpyrrolidone K-90 polymers.
Shih Jenn S. (Paramus NJ) Chuang Jui-Chang (Wayne NJ) Login Robert B. (Oakland NJ), Process for making polyvinylpyrrolidone polymer having predetermined characteristics.
Le Boeuf Albert R. (Sturbridge MA) Grovesteen William R. (West Dudley MA), Pyrrolidone-methacrylate graft copolymers from 3-stage polymerization process.
Seidner Leonard (Brooklyn NY) Spinelli Harry J. (Wilington DE) Ali Mohammed I. (Aberdeen NJ) Weintraub Lester (Mount Laurel NJ), Silicone-containing contact lens polymers, oxygen permeable contact lenses and methods for making these lenses and treat.
Seidner Leonard (Brooklyn NY) Spinelli Harry J. (Wilington DE) Ali Mohammed I. (Aberdeen NJ) Weintraub Lester (Mount Laurel NJ), Silicone-containing contact lens polymers, oxygen permeable contact lenses and methods for making these lenses and treat.
Anton Waifong L. (Claymont DE) Coleman Henry D. (Brooklyn NY) Ali Mohammed I. (Aberdeen NJ) Weintraub Lester (Mount Laurel NJ), Silicone-containing polymers, compositions and improved oxygen permeable hydrophilic contact lenses.
Spinelli Harry J. (Wilmington DE) Anton Waifong L. (Claymont DE) Seidner Leonard (Brooklyn NY) Coleman Henry D. (Brooklyn NY) Ali Mohammed I. (Aberdeen NJ) Weintraub Lester (Mount Laurel NJ) White Pa, Silicone-containing polymers, oxygen permeable hydrophilic contact lenses and methods for making these lenses and treati.
Nakada Kazuhiko,JPX ; Matano Yutaka,JPX, Solution for preserving contact lenses for shipping and method for preserving contact lenses for shipping employing it.
Goldberg Eugene P. (Gainesville FL) Burns James W. (Holliston MA) Kumar G. Sudesh (Maharastra MO INX) Osborn David C. (Manchester MO) Larson Jeffrey A. (Santa Barbara CA) Sheets John W. (Pasadena CA), Surface modified surgical instruments, devices, implants, contact lenses and the like.
Goldberg Eugene P. (Gainesville FL) Burns James W. (Natick MA) Kumar G. Sudesh (Maharastra MO INX) Osborn David C. (St. Louis MO) Larson Jeffrey A. (Monrovia CA) Sheets John W. (Clearmont CA) Yahiaou, Surface modified surgical instruments, devices, implants, contact lenses and the like.
Goldberg Eugene P. (Gainesville FL) Vahiaoui Ali (Gainesville FL), Surface modified surgical instruments, devices, implants, contact lenses and the like.
Su Kai C. (Alpharetta GA) Robertson J. Richard (Alpharetta GA), Wettable, flexible, oxygen permeable, substantially non-swellable contact lens containing block copolymer polysiloxane-p.
Robertson J. Richard (Alpharetta GA) Su Kai C. (Alpharetta GA), Wettable, rigid gas permeable, substantially non-swellable contact lens containing block copolymer polysiloxane-polyoxya.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.