An apparatus and system for treating a wound having a cavity is disclosed. The apparatus comprises a scaffold including a scaffold lamina and a tissue lamina wherein the scaffold lamina forms a laminate in fluid communication with the tissue lamina. The laminate is rolled into a generally cylindrica
An apparatus and system for treating a wound having a cavity is disclosed. The apparatus comprises a scaffold including a scaffold lamina and a tissue lamina wherein the scaffold lamina forms a laminate in fluid communication with the tissue lamina. The laminate is rolled into a generally cylindrical shape having two end surfaces. The apparatus further comprises a manifold having a port for coupling to a source of reduced pressure and that is positioned in fluid communication with the scaffold to provide reduced pressure to the scaffold lamina and the wound. The apparatus also comprises a drape formed of substantially impermeable material to cover the scaffold and the manifold within the wound. A method for treating a wound having a cavity is also disclosed and comprises positioning a scaffold lamina adjacent a tissue lamina to form a laminate in fluid communication with the tissue lamina, rolling the laminate into a generally cylindrical shape having two end surface, and positioning the scaffold within the cavity of the wound to provide reduced pressure to the wound. The method further comprises positioning a manifold in fluid communication with the scaffold to provide reduced pressure to the scaffold lamina and the wound.
대표청구항▼
1. A system for,treating a wound having a cavity, the system comprising: a pressure source to supply reduced pressure;a scaffold having a generally cylindrical shape having a first end surface adapted to be inserted into the cavity of the wound and a second end surface adapted to receive reduced pre
1. A system for,treating a wound having a cavity, the system comprising: a pressure source to supply reduced pressure;a scaffold having a generally cylindrical shape having a first end surface adapted to be inserted into the cavity of the wound and a second end surface adapted to receive reduced pressure from the pressure source to be provided to the wound, and comprising (i) a scaffold lamina being formed from a strip of material having surfaces extending between two edges, wherein the material includes a reticulated foam having a porous structure adaptedtoprovide a structural matrix for the formation of tissue within the cavity of the wound and support protein adhesion, and(ii) a tissue lamina being formed from a strip of material having surfaces extending between two edges, wherein the surfaces of the tissue lamina and the scaffold lamina are in fluid communication and rolled into the generally cylindrical shape of the scaffold and the edges of the tissue lamina and the scaffold lamina form the first and second end surfaces of the scaffold, respectively; anda manifold in fluid communication with the pressure source and the second end surface of the scaffold to provide reduced pressure to the scaffold lamina and the wound. 2. The system of claim 1, further comprising a drape formed of substantially impermeable material to cover the scaffold and the manifold within the wound to substantially maintain the reduced pressure within the wound when provided by the manifold. 3. The system of claim 1, wherein the manifold is positioned adjacent the second end surface of the scaffold. 4. The system of claim 1, wherein an end portion of the scaffold lamina is in fluid communication with the manifold. 5. The system of claim 1, wherein the tissue lamina comprises adipose tissue. 6. The system of claim 5, wherein the adipose tissue is derived from lipoaspirate. 7. The system of claim 1, wherein the tissue lamina comprises allograft, autograft or xenograft tissue. 8. The system of claim 1, wherein the scaffold lamina is formed from a bioinert or bioabsorbable material. 9. The system of claim 1, wherein the scaffold lamina comprises a bioactive agent selected from the group consisting of an antibiotic, an antibody, and a growth factor. 10. The system of claim 9, wherein the bioactive agent is a growth hormone (GH), a bone morphogenetic protein (BMP), transforming growth factor-α (TGF-α), a TGF-β, a fibroblast growth factor (FGF), granulocyte-colony stimulating factor (G-CSF), granulocyte/macrophage-colony stimulating factor (GM-CSF), epidermal growth factor (EGF), platelet derived growth factor (PDGF), insulin-like growth factor (IGF), vascular endothelial growth factor (VEGF), hepatocyte growth factor/scatter factor (HGF/SF), an interleukin, tumor necrosis factor-α (TNF-α) or nerve growth factor (NGF). 11. The system of claim 8, wherein the scaffold lamina is composed of collagen. 12. The system of claim 1, wherein the manifold is composed of a bioinert material. 13. The apparatus of claim 1, wherein the manifold is composed of a bioabsorbable material. 14. The system of claim 1, wherein the scaffold lamina comprises a high void fraction for the growth of cells and the formation of tissue. 15. The system of claim 1, wherein the scaffold lamina comprises a material adapted to support cellular ingrowth. 16. The system of claim 1, wherein a thickness of the scaffold lamina is greater than a thickness of the tissue lamina.
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