A cover for a substrate including: a body defining a cavity, for positioning over the substrate to form a reaction chamber; and a projection extending from the body to define a fluid reservoir, when the cover is fitted to the substrate, the fluid reservoir being in fluid communication with the cavit
A cover for a substrate including: a body defining a cavity, for positioning over the substrate to form a reaction chamber; and a projection extending from the body to define a fluid reservoir, when the cover is fitted to the substrate, the fluid reservoir being in fluid communication with the cavity.
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1. A cover for a microscope slide comprising: a body defining a cavity when positioned over the microscope slide to form a reaction chamber, said body positioned such that a space of a first height is provided between a top surface of the slide and a bottom surface of the body, said space defining t
1. A cover for a microscope slide comprising: a body defining a cavity when positioned over the microscope slide to form a reaction chamber, said body positioned such that a space of a first height is provided between a top surface of the slide and a bottom surface of the body, said space defining the cavity;a projection extending from a first end of the body and laterally across a width of the body and being positioned above the bottom surface of the body to define a fluid reservoir with the top surface of the microscope slide when positioned over the slide, said fluid reservoir having a second height greater than the first height where the second height corresponds to a distance from the top surface of the slide to a bottom surface of the projection, the fluid reservoir being separate from and in fluid communication with the cavity; andan outlet at a second end of the cover distal from the first end. 2. A cover for a microscope slide according to claim 1, wherein the bottom surface of the body is supported on the slide. 3. A cover for a microscope slide according to claim 1 wherein the bottom surface of the body is substantially supported on the slide. 4. A cover for a microscope slide according to claim 1, wherein a portion of the bottom surface of the body is inclined with respect to the top surface of the microscope slide by a first angle, θ1 which is greater than zero. 5. A cover for a microscope slide according to claim 4, wherein a portion of the bottom surface of the projection is inclined with respect to the top surface of the microscope slide by a second angle, θ2, which is greater than zero. 6. A cover for a microscope slide according to claim 5, wherein θ2 is greater than θ1. 7. A cover for a microscope slide according to claim 6, the projection further comprising two lateral sides and a distal end wherein the projection is tapered on each lateral side such that the width of the projection gets smaller towards the projection distal end. 8. A cover for a microscope slide according to claim 7, the projection further comprising a fluid receiving zone. 9. A cover for a microscope slide according to claim 8, wherein the fluid receiving zone is arcuate. 10. A cover for a microscope slide according to claim 8, wherein the fluid receiving zone is semicircular. 11. A cover for a microscope slide according to claim 1, wherein the bottom surfaces of the projection and the body each have planar portions used to define the first and second heights respectively. 12. A cover for a microscope slide according to claim 1, wherein the projection has protruding section with an indent. 13. A cover for a microscope slide according to claim 1, wherein the first end is an external end and the second end is an external end opposite the first end across a length of the body. 14. A cover for a microscope slide comprising: a body defining a cavity when positioned over the microscope slide to form a reaction chamber, said body including a bottom surface substantially supported on the slide such that a space defining the reaction chamber is provided between a top surface of the slide and the bottom surface of the body; anda protruding section extending from an exterior first end of the body and laterally across a width of the body having tapered corners and being positioned above the bottom surface of the body to define a fluid reservoir with the top surface of the microscope slide when positioned over the slide,wherein the fluid reservoir is in fluid communication with the reaction chamber. 15. A microscope slide processing module, comprising: a tray capable of holding a plurality of microscope slides;at least one of the plurality of microscope slides provided on the tray and having indicia thereon for providing information related to the slide; anda cover configured to be positioned over the slide and including a body having sealing portions extending therefrom which define a sealing chamber with the slide when the cover is positioned over the slide, said cover being configured to receive a clamping force to provide a seal between the sealing portions and the slide,wherein the cover is configured to be lifted relative to the slide so as to be displaced therefrom by a lifting mechanism provided on the cover,wherein in an opened position the lifting mechanism is configured to maintain engagement with the tray. 16. A microscope slide processing module, comprising a tray capable of holding a plurality of microscope slides;at least one of the plurality of microscope slides provided on the tray and having indicia thereon for providing information related to the slide; anda cover including a body defining a cavity when positioned over the microscope slide to form a reaction chamber, said cover only partially covering the slide such that the indicia is uncovered,wherein the cover is configured to be lifted relative to the slide so as to be displaced therefrom by a lifting mechanism provided on the cover,wherein in an opened position the lifting mechanism is configured to maintain engagement with the tray. 17. The microscope slide processing module of claim 16, wherein said cover is configured to receiving a clamping force to provide a seal between sealing portions of the cover and the slide. 18. A cover for a microscope slide comprising: a body defining a cavity when positioned over the microscope slide to form a reaction chamber, said body including a bottom surface and barrier walls which support the body such that a space is provided between a top surface of the slide and the bottom surface of the body, said space defining the cavity; anda protruding section extending from an external end of the body and laterally across a width of the body to define a fluid receiving zone, the fluid receiving zone being separate from and in fluid communication with the cavity. 19. A cover for a microscope slide according to claim 18, wherein the fluid receiving zone is arcuate. 20. A cover for a microscope slide according to claim 18, wherein the fluid receiving zone is semicircular. 21. A method of treatment of a sample on a sample holding region of a microscope slide, comprising: locating a cover over the microscope slide, so that a cavity having a first height relative to the slide is provided to form a closed reaction chamber over the sample holding region; anddepositing fluid into a fluid reservoir having a second height relative to the microscope slide to allow the fluid to be drawn along the slide and into the reaction chamber,wherein the second height greater than the first height, andthe fluid reservoir and the reaction chamber contact each other in a covered state. 22. A method of treatment of a sample on a sample holding region of a microscope slide according to claim 21, further comprising adjusting the position of the cover with respect to the microscope slide so as to change the size of the reaction chamber.
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이 특허에 인용된 특허 (12)
Chu, Wei-Sing, Apparatus and methods for efficient processing of biological samples on slides.
Bowman David J. (Manchester GB2) Cosgrove Raymond F. (Wallasey GB2) Male Terence P. (Helsby GB2) Evans Robert (Liverpool GB2), Tissue processing apparatus.
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