Compositions and methods for reducing body fat
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61K-031/165
A61K-031/5575
A61K-009/00
출원번호
US-0504788
(2014-10-02)
등록번호
US-9144574
(2015-09-29)
발명자
/ 주소
Grosskreutz, Cynthia L.
Pasquale, Louis R.
Singer, Michael S.
Kalayoglu, Murat V.
출원인 / 주소
Topokine Therapeutics, Inc.
대리인 / 주소
Wolf, Greenfield & Sacks, P.C.
인용정보
피인용 횟수 :
7인용 특허 :
53
초록
The present invention relates to compositions, such as bimatoprost, latanoprost and travoprost, and methods to reduce fat in the body of an individual, for example, by topical administration, injection, and/or implantation of such compositions.
대표청구항▼
1. A method for reducing fat in a body of an individual, the method comprising administering to the skin of a portion of the body a composition comprising bimatoprost, represented by the formula: or a 9-, 11-, or 15-ester thereof, or a pharmaceutically acceptable salt thereof; wherein the portion o
1. A method for reducing fat in a body of an individual, the method comprising administering to the skin of a portion of the body a composition comprising bimatoprost, represented by the formula: or a 9-, 11-, or 15-ester thereof, or a pharmaceutically acceptable salt thereof; wherein the portion of the body has an excess deposit of body fat. 2. The method of claim 1, wherein the individual has a cosmetic condition that comprises excess body fat. 3. The method of claim 1, wherein the individual has obesity. 4. The method of claim 1, wherein the excess deposit of body fat comprises obesity. 5. The method of claim 1, wherein the excess deposit of body fat is diffuse. 6. The method of claim 1, wherein the excess deposit of body fat is local. 7. The method of claim 1, wherein the excess deposit of body fat is on an area of the body selected from the group consisting of face, chin, neck, arms, chest, abdomen, buttocks, hips, thighs, and legs. 8. The method of claim 1, wherein the reducing occurs at a localized area selected from the group consisting of face, chin, neck, arms, chest, abdomen, buttocks, hips, thighs, and legs. 9. The method of claim 1, wherein the administering is to a localized area selected from the group consisting of face, chin, neck, arms, chest, abdomen, buttocks, hips, thighs, and legs. 10. The method of claim 1, wherein the route of administration is local. 11. The method of claim 1, wherein the composition is selected from the group consisting of a solution, a cream, an ointment, a gel, a lotion, a foam, a spray, a patch, and an implantable depot. 12. The method of claim 1, wherein the composition comprises a sustained-release formulation. 13. The method of claim 1, wherein the route of administration is selected from the group consisting of topical, subcutaneous, intradermal, subdermal, and transdermal. 14. The method of claim 13, wherein the route of administration is topical. 15. The method of claim 13, wherein the route of administration is subcutaneous. 16. The method of claim 13, wherein the route of administration is intradermal. 17. The method of claim 13, wherein the route of administration is subdermal. 18. The method of claim 13, wherein the route of administration is transdermal. 19. The method of claim 1, wherein the composition comprises bimatoprost.
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