Integrated delivery device for continuous glucose sensor
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61M-031/00
A61M-001/00
A61M-005/315
A61B-005/00
A61B-005/145
G06F-019/00
A61M-005/172
A61B-005/1486
출원번호
US-0559454
(2012-07-26)
등록번호
US-9155843
(2015-10-13)
발명자
/ 주소
Brauker, James H.
Tapsak, Mark A.
Saint, Sean T.
Kamath, Apurv Ullas
Neale, Paul V.
Simpson, Peter C.
Mensinger, Michael Robert
Markovic, Dubravka
출원인 / 주소
DexCom, Inc.
대리인 / 주소
Knobbe Martens Olson & Bear, LLP
인용정보
피인용 횟수 :
1인용 특허 :
270
초록▼
Systems and methods for integrating a continuous glucose sensor, including a receiver, a medicament delivery device, and optionally a single point glucose monitor are provided. Manual integrations provide for a physical association between the devices wherein a user (for example, patient or doctor)
Systems and methods for integrating a continuous glucose sensor, including a receiver, a medicament delivery device, and optionally a single point glucose monitor are provided. Manual integrations provide for a physical association between the devices wherein a user (for example, patient or doctor) manually selects the amount, type, and/or time of delivery. Semi-automated integration of the devices includes integrations wherein an operable connection between the integrated components aids the user (for example, patient or doctor) in selecting, inputting, calculating, or validating the amount, type, or time of medicament delivery of glucose values, for example, by transmitting data to another component and thereby reducing the amount of user input required. Automated integration between the devices includes integrations wherein an operable connection between the integrated components provides for full control of the system without required user interaction.
대표청구항▼
1. A diabetes management system for semi-automated integration of a continuous glucose sensor and a medicament delivery device to maintain a host's glucose levels within a desired target range, the system comprising: a continuous glucose sensor configured to continuously measure glucose in a host an
1. A diabetes management system for semi-automated integration of a continuous glucose sensor and a medicament delivery device to maintain a host's glucose levels within a desired target range, the system comprising: a continuous glucose sensor configured to continuously measure glucose in a host and to output a data stream including one or more sensor data points;a processor module operably connected to the continuous glucose sensor, wherein the processor module is configured to receive the data stream, evaluate a clinical risk, determine whether to operate in either a first mode or a second mode based on whether the clinical risk meets one or more predetermined criteria, and send therapy instructions to a medicament delivery device in the first mode but not in the second mode; anda medicament delivery device operably connected to the processor module and configured to receive and execute the therapy instructions. 2. The diabetes management system of claim 1, wherein the clinical risk is an identified danger or potential risk to the health of the host based on a glucose concentration value of the host measured by the continuous glucose sensor. 3. The diabetes management system of claim 1, wherein the clinical risk is an identified danger or potential risk to the health of the host based on a rate of change of the glucose concentration of the host measured by the continuous glucose sensor. 4. The diabetes management system of claim 1, wherein the clinical risk is an identified danger or potential risk to the health of the host based on an acceleration of the glucose concentration of the host measured by the continuous glucose sensor. 5. The diabetes management system of claim 1, wherein the clinical risk is determined based on an evaluation of a glucose value measured by a single point glucose monitor. 6. A method for calculating and sending therapy instructions to a medicament delivery device to maintain a host's glucose levels within a desired target range, the method comprising: generating a data stream from a substantially continuous glucose sensor, the data stream including one or more sensor data points;receiving the data stream, by a processor module;detecting, by the processor module, a clinical risk; andcalculating, by the processor module, instructions for administration of a medicament by a medicament delivery device; anddetermining, by the processor module, whether to send the instructions for administration of the medicament to the medicament delivery device based on whether the clinical risk meets a predetermined criterion; andsending the instructions to the medicament delivery device based on the determination. 7. The method of claim 6, wherein the clinical risk is an identified danger or potential risk to the health of the host based on a measured or estimated glucose concentration value of the host. 8. The method of claim 6, wherein the clinical risk is an identified danger or potential risk to the health of the host based on a measured or estimated rate of change of the glucose concentration of the host. 9. The method of claim 6, wherein the clinical risk is an identified danger or potential risk to the health of the host based on an estimated or measured acceleration of the glucose concentration of the host. 10. The method of claim 6, wherein the clinical risk is determined based on clinical acceptability evaluation of a discrepancy between a glucose value measured by a single point glucose monitor and the one or more sensor data points of the continuous glucose sensor that could cause a risk to the patient if incorrect therapy is administered. 11. An integrated diabetes management system comprising a non-transitory computer readable medium stored in memory that is configured to cause a processor to receive a data stream from a substantially continuous glucose sensor, the data stream including one or more sensor data points, calculate a therapy comprising instructions for administration of a medicament, and automatically send the instructions to a medicament delivery device in a fully-automated mode unless a semi-automated mode is triggered, wherein the fully automated mode does not require user interaction to send instructions to the medicament delivery device, wherein the semi-automated mode requires user interaction before sending instructions to the medicament delivery device, and wherein the semi-automated mode is triggered responsive to detection of a clinical risk.
연구과제 타임라인
LOADING...
LOADING...
LOADING...
LOADING...
LOADING...
이 특허에 인용된 특허 (270)
Starkweather, Timothy J.; Lebel, Ronald J.; Shahmirian, Varaz; Weiss, Philip T., Ambulatory medical apparatus and method having telemetry modifiable control software.
Lebel, Ronald J.; Shahmirian, Varaz; Starkweather, Timothy J.; Weiss, Philip T.; Villegas, Daniel H.; Dennard, Robert C.; Armstrong, John T.; Richert, John D., Ambulatory medical apparatus and method using a telemetry system with predefined reception listening periods.
Say James ; Tomasco Michael F. ; Heller Adam ; Gal Yoram,ILX ; Aria Behrad ; Heller Ephraim ; Plante Phillip John ; Vreeke Mark S. ; Friedman Keith A. ; Colman Fredric C., Analyte monitoring device and methods of use.
Causey ; III James D. ; Kovelman Paul H. ; Purvis Richard E. ; Mastrototaro John J., Analyte sensor and holter-type monitor system and method of using the same.
Bcker Dirk (Heidelberg DEX) Haar Hans-Peter (Wiesloch DEX) Blasberg Peter (Weinheim DEX) Kotulla Reinhard (Lambsheim DEX), Analytical system for monitoring a substance to be analyzed in patient-blood.
Fuller Milton E. (500 Winchester Dr. Reno NV 89506) Cherne Frank J. (1295 Wesley Dr. Reno NV 89503), Apparatus and method for radio frequency spectroscopy using spectral analysis.
Simons Tad Decatur ; Greenstein Michael ; Freeman Dominique ; Leonard Leslie Anne ; King David A. ; Lum Paul, Cassette of lancet cartridges for sampling blood.
Steil, Garry M.; Rebrin, Kerstin; Goode, Jr., Paul V.; Mastrototaro, John J.; Purvis, Richard E.; Van Antwerp, William P.; Shin, John J.; Talbot, Cary D., Closed loop system for controlling insulin infusion.
Malave, Luis J.; Estes, Mark C.; Yonemoto, Jay; Barlow, J. Jeffrey; Gross, Todd M.; Shin, John; Cheney, II, Paul S.; Dobbles, Mike; Hague, Clifford W.; Ruppert, Deborah; Wells, Kevin C., Communication station and software for interfacing with an infusion pump, analyte monitor, analyte meter, or the like.
Gough David A. (Cardiff CA) Lucisano Joseph Y. (La Jolla CA) Armour Jon C. (La Jolla CA) McKean Brian D. (San Diego CA), Complete glucose monitoring system with an implantable, telemetered sensor module.
Ham Fredric M. (Indialantic FL) Cohen Glenn M. (Indialantic FL), Determination of concentrations of biological substances using raman spectroscopy and artificial neural network discrimi.
Bret Berner ; Chia-Ming Chiang ; Michael D. Garrison ; Janan Jona ; Russell O. Potts ; Janet A. Tamada ; Michael J. Tierney, Device for monitoring of physiological analytes.
Berner, Bret; Dunn, Timothy C.; Farinas, Kathleen C.; Garrison, Michael D.; Kurnik, Ronald T.; Lesho, Matthew J.; Potts, Russell O.; Tamada, Janet A.; Tierney, Michael J., Device for signal processing for measurement of physiological analytes.
James Say ; Michael F. Tomasco ; Adam Heller ; Yoram Gal IL; Behrad Aria ; Ephraim Heller ; Phillip John Plante ; Mark S. Vreeke, Electrochemical analyte sensor.
Maley Thomas C. (Medway MA) D\Orazio Paul A. (Mendon MA) Dalzell Bonnie C. (Sherborn MA) Edelman Peter G. (Franklin MA) Flaherty James E. (Attleboro MA) Mason Richard W. (Millis MA) McCaffrey Robert , Electrochemical sensors.
D\Orazio Paul A. (Mishawaka IN) Eddy ; Jr. Arthur R. (Depew NY) Fogt Eric J. (Maple Grove MN) Jones James E. (Elkhart IN) Oberhardt Bruce J. (Mishawaka IN), Enzyme electrode membrane.
Gregg Brian A. (13940 Braun Dr. Golden CO 80401) Heller Adam (5317 Valburn Cir. Austin TX 78731) Kerner Wolfgang (Universitat Zu Lubeck ; Klinik Fur Innerere Medizin ; Razeburger Allee 160 D-2400 Lub, Enzyme electrodes.
Lord Peter C. (Santa Clarita CA) Van Antwerp William P. (Brentwood CA) Mastrototaro John J. (Los Angeles CA) Cheney ; II Paul S. (Beverly Hills CA) Schnabel Nannette M. (Valencia CA), Flex circuit connector.
Savage Douglas R. (Del Mar CA) Betts Ronald E. (La Jolla CA) Koerner Richard J. (San Diego CA) Hillier Douglas R. (San Juan Capistrano CA), Fluid sample analyte collector and calibration assembly.
Schulman Joseph H. (10650 Comet Way Santa Clarita CA 91351) Rule ; III Orville R. (2572 Basil La. Los Angeles CA 90077), Fluidic infusion system for catheter or probe.
Young Chung C. (Weston MA) Gary Kenneth (Belmont MA) Winarta Handani (Waltham MA) Chen Chin-Chun (Wayland MA), Glucose electrode and method of determining glucose.
Schulman Joseph H. (Santa Clarita CA) Rule ; III Orville R. (Los Angeles CA) Whitmoyer David I. (Los Angeles CA) Lebel Ronald J. (Sherman Oaks CA) Lucisano Joseph Y. (Saugus CA) Mann Alfred E. (Bever, Glucose monitoring system.
Schulman Joseph H. (Santa Clarita CA) Rule ; III Orville Rey (Los Angeles CA) Whitmoyer David I. (Los Angeles CA) Lebel Ronald J. (Sherman Oaks CA) Lucisano Joseph Y. (Saugus CA) Mann Alfred E. (Beve, Glucose sensor assembly.
Allen Douglas J. (Indianapolis IN) Johnson Kirk W. (Indianapolis IN) Nevin Robert S. (Indianapolis IN), Hydrophilic polyurethane membranes for electrochemical glucose sensors.
Dionne Keith E. ; Emerich Dwaine F. ; Hoffman Diane ; Sanberg Paul R. ; Christenson Lisa ; Hegre Orion D. ; Scharp David W. ; Lacy Paul E. ; Aebischer Patrick,CHX ; Vasconcellos Alfred V. ; Lysaght M, Implantable biocompatable immunoisolatory vehicle for delivery of selected therapeutic products.
Joseph H. Schulman ; Charles L. Byers ; Gerald E. Adomian ; Michael S. Colvin, Implantable enzyme-based monitoring systems having improved longevity due to improved exterior surfaces.
Bessman Samuel P. (2025 Zonal Ave. Los Angeles CA 90033) Layne Ennis C. (9128 Huntington Dr. San Gabriel CA 91775) Thomas Lyell J. (1900 Pelican Ave. San Pedro CA 90732), Implantable glucose sensor.
Wilson George S. (Lawrence KS) Bindra Dilbir S. (Lawrence KS) Hill Brian S. (Lawrence KS) Thevenot Daniel R. (Paris Cedex FRX) Sternberg Robert (Thiais FRX) Reach Gerard (Paris Cedex KS FRX) Zhang Ya, Implantable glucose sensor.
Kimball Victor E. ; Lynch Laurie E. ; Pierskalla Irvin T. ; Porter Christopher H., In situ calibration system for sensors located in a physiologic line.
Brauker, James H.; Tapsak, Mark A.; Saint, Sean T.; Kamath, Apurv U.; Neale, Paul V.; Simpson, Peter C.; Mensinger, Michael Robert; Markovic, Dubravka, Integrated delivery device for continuous glucose sensor.
D\Angelo Joseph P. (Miami FL) Schur Henry B. (Miami FL) Han Kedu (Miami FL) Glenn Daniel J. (Hollywood FL), Integrated system for biological fluid constituent analysis.
Gravel Marian ; Gasparello Benjamin ; Ferraro Joseph ; Sharma Ashutosh ; Strowe Robert John ; Bendek Antonio A. ; Uschold Robert C. ; Antoshkiw William Thomas, Integrated system including medication delivery pen, blood monitoring device, and lancer.
Erickson Brian J. (Woodbury MN) Hilgers Michael E. (Roseville MN) Hendrickson Tracy A. (Minnetonka MN) Shapland J. Edward (Shoreview MN) Solomon Frank A. (Plymouth MN) Knudson Mark B. (Shoreview MN), Interstitial fluid collection and constituent measurement.
Liess Hans D. (Muensing DEX) Heinze Roland (Munich DEX), Measuring instrument for intracardial acquisition of the blood oxygen saturation of a patient for controlling the pacing.
Poulsen,Jens Ulrik; Christensen,Lars Hofmann; Aasmul,Soren, Method and a system for assisting a user in a medical self treatment, said self treatment comprising a plurality of actions.
Yacynych Alexander (2 Bernard Rd. East Brunswick NJ 08816), Method for making electrochemical sensors and biosensors having a polymer modified surface.
Genshaw Marvin A. (Elkhart IN) Huang Dijia (Granger IN) Musho Matthew K. (Granger IN) Yip Kin Fai (Elkhart IN), Method for reducing bias in amperometric sensors.
Khalil, Omar S.; Yeh, Shu-jen; Hanna, Charles F.; Kantor, Stanislaw, Method for the non-invasive determination of analytes in a selected volume of tissue.
Bartkowiak, Miroslaw; Harper, Wesley S.; Kulcu, Eray; Lesho, Matthew J.; Tamada, Janet A., Micropressors, devices and methods for use in analyte monitoring systems.
Lebel, Ronald J.; Shahmirian, Varaz; Bowman, IV, Sam W.; Starkweather, Timothy J.; Morgan, Wayne A., Microprocessor controlled ambulatory medical apparatus with hand held communication device.
Lebel, Ronald J.; Shahmirian, Varaz; Bowman, IV, Sam W.; Starkweather, Timothy J.; Morgan, Wayne A., Microprocessor controlled ambulatory medical apparatus with hand held communication device.
Lebel, Ronald J.; Shahmirian, Varaz; Bowman, IV, Sam W.; Starkweather, Timothy J.; Villegas, Daniel H.; Choy, David Y.; Weiss, Philip T., Microprocessor controlled ambulatory medical apparatus with hand held communication device.
Lebel, Ronald J.; Shahmirian, Varaz; Starkweather, Timothy J.; Villegas, Daniel H.; Weiss, Philip T., Microprocessor controlled ambulatory medical apparatus with hand held communication device.
Bartkowiak, Miroslaw; Harper, Wesley S.; Kulcu, Eray; Lesho, Matthew J.; Tamada, Janet A., Microprocessors, devices and methods for use in analyte monitoring systems.
Berner Bret ; Chiang Chia-Ming ; Garrison Michael D. ; Jona Janan ; Potts Russell O. ; Tamada Janet A. ; Tierney Michael J., Monitoring of physiological analytes.
McCaffrey Robert (Franklin MA) Dalzell Bonnie (Sherborn MA) Tkacik Katarina (Concord MA) Holbert Susan (Holliston MA) Boden Mark (Millbury MA) Flaherty James (Attleboro MA) Flanagan Michael (Needham , Multilayer enzyme electrode membranes and methods of making same.
Tarr Randall V. (Atlanta GA) Steffes Paul G. (Norcross GA), Non-invasive blood glucose measurement system and method using stimulated Raman spectroscopy.
Oka Tohru,JPX ; Takakura Makoto,JPX, Physical information monitor system having means for determining reference range for abnormality determination, based.
Clark ; Jr. Leland (Cincinnati OH), Polarographic method for measuring both analyte and oxygen with the same detecting electrode of an electroenzymatic sens.
Fidler John C. (DeKalb) Bobis James P. (Downers Grove) Penrose William R. (Naperville) Stetter Joseph R. (Naperville IL), Potentiostatic apparatus and methods.
Shin, John J.; Holtzclaw, Kris R.; Dangui, Nandita D.; Kanderian, Jr., Sami; Mastrototaro, John J.; Hong, Peter I., Real time self-adjusting calibration algorithm.
Berner Bret ; Dunn Timothy C. ; Farinas Kathleen C. ; Garrison Michael D. ; Kurnik Ronald T. ; Lesho Matthew J. ; Potts Russell O. ; Tamada Janet A. ; Tierney Michael J., Signal processing for measurement of physiological analysis.
Alvarez Khristopher Edward ; Berry Paul Anthony ; Stanga Michael Allen ; Strong Michael Raymond, Silicone gel composition and silicone gel produced therefrom.
Benjamin J. Feldman ; Adam Heller ; Ephraim Heller ; Fei Mao ; Joseph A. Vivolo ; Jeffery V. Funderburk ; Fredric C. Colman ; Rajesh Krishnan, Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator.
Keith,Steven; Parker,Robert S.; Harvey,Noel G.; Pettis,Ronald J.; DeNuzzio,John D.; Vonk,Glenn, System and method for initiating and maintaining continuous, long-term control of a concentration of a substance in a patient using a feedback or model-based controller coupled to a single-needle or .
Starkweather, Timothy J.; Lebel, Ronald J.; Shah, Rajiv; Miller, Michael E., System and method for providing closed loop infusion formulation delivery.
Talbot, Cary D.; Estes, Mark C.; Mastrototaro, John J.; Moberg, Sheldon B.; Mueller, Jr., John C.; Vallet Tolle, “Mike” Charles; Williams, Gary L., System for providing blood glucose measurements to an infusion device.
Grill ; Jr. Warren M. (Cleveland Hts. OH) Creasey Graham H. (Cleveland Hts. OH) Ksienski David A. (Hermosa Beach CA) Veraart Claude S. (Brussels OH BEX) Mortimer J. Thomas (Chagrin Falls OH), Thin film implantable electrode and method of manufacture.
Brauker James H. (Harvard IL) Hill Ronald S. (Grayslake IL) Martinson Laura A. (Lake Villa IL) Boggs Daniel R. (Libertyville IL) Johnson Robert C. (Bartlett IL), Tissue inplant systems and methods for sustaining viable high cell densities within a host.
Cheney ; II Paul S. (Beverly Hills CA) Mastrototaro John J. (Los Angeles CA) Schnabel Nannette M. (Valencia CA) Lord Peter C. (Valencia CA) Van Antwerp William P. (Los Angeles CA) Clark Raymond D. (V, Transcutaneous sensor insertion set.
Lord Peter C. (Santa Clarita CA) Van Antwerp William P. (Brentwood CA) Mastrototaro John J. (Los Angeles CA) Cheney ; II Paul S. (Beverly Hills CA) Schnabel Nannette M. (Valencia CA), Transcutaneous sensor insertion set.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.