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Formulations for topical delivery of bioactive substances and methods for their use 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61Q-017/04
  • A61Q-019/00
  • A61K-008/37
  • A61K-008/66
  • A61K-047/14
  • A61K-008/46
  • A61K-008/67
  • A61K-008/97
  • A61K-009/00
  • A61K-009/14
  • A61K-047/10
  • A61K-047/42
  • A61K-047/44
  • A61Q-017/00
출원번호 US-0535213 (2006-09-26)
등록번호 US-9162084 (2015-10-20)
발명자 / 주소
  • Vromen, Jacob
출원인 / 주소
  • CellMedics, Inc.
대리인 / 주소
    Verrill Dana LLP
인용정보 피인용 횟수 : 0  인용 특허 : 30

초록

The invention relates to topical delivery of bioactive agents. More particularly, the invention relates to anhydrous formulations for percutaneous absorption. The invention provides formulations that allow efficient topical delivery of high concentrations of bioactive substances for percutaneous abs

대표청구항

1. An anhydrous topical cream delivery formulation for percutaneous absorption consisting essentially of capric/caprylic triglyceride, glycerol, beta hydroxy acid, and one or more diethylene glycol monoethyl ether, dimethyl isosorbide, propylene glycol, oleic acid, epidermal enzymes, ethanol and dim

이 특허에 인용된 특허 (30)

  1. Cragoe ; Jr. Edward J. (Lansdale PA) Jones James H. (Blue Bell PA), 8-Aza-9-oxo(and dioxo)-thia-11,12-secoprostaglandins.
  2. Riedl Jutta (Berlin DEX) Gnther Clements (Berlin DEX) Lipp Ralph (Berlin DEX), Agent for transdermal administration containing ergoline derivatives.
  3. Ramirez Jose E. (Trumbull CT) Vishnupad Mohan (Monroe CT), Anhydrous foaming composition containing low concentrations of detergents and high levels of glycerin and emollients suc.
  4. Burnett Katherine M. ; Kurtz Ellen S., Anhydrous topical skin preparations.
  5. Hale Ron L. (Woodside CA) Lu Amy (Los Altos CA) Solas Dennis (San Francisco CA) Selick Harold E. (Belmont CA) Oldenburg Kevin R. (Fremont CA) Zaffaroni Alejandro C. (Atherton CA), Compositions and methods for enhanced drug delivery.
  6. Jacob Vromen AU, Cosmetic compositions comprising exfoliating enzymes and uses thereof.
  7. Fallon Renee A. (Sunnyvale CA) Wilson Donald R. (San Francisco CA), Device for administering drug transdermally which provides an initial pulse of drug.
  8. Ecanow Bernard (Wilmette IL), Drug delivery compositions and methods.
  9. Voss Gene (213 Alcade Moreno San Antonio TX 78232) Eichler Allen C. (1347 Lockhill-Selma San Antonio TX 78213), Impotence ointment.
  10. Eibl Hansjrg (Bovenden DEX), Medicament with improved penetration of the tissue membrane.
  11. Gardner John P. (El Paso TX), Method for nutritional oxygenation of the skin.
  12. Latorre ; Alvaro, Method of effecting and enhancing an erection.
  13. Curtis Ernest S. ; Kalafsky Robert ; Kaplan Elinor R., Method of treating the skin with organic acids in anhydrous microsphere delivery systems.
  14. Masiz John J. (26 High St. Topsfield MA 01983), Molecular transdermal transport system.
  15. Vargas Anthony (Monroe CT) Asplund Pamela C. (Shelton CT) Corcoran Cathleen (Bridgeport CT), Non-irritating a 상세보기
  • Allec Josiane (Antibes FRX) Ferrara Eve (Le Cannet FRX) Bara Isabelle (Paris FRX), Nongreasy/nonsticky fatty cosmetic/dermatological compositions.
  • Neumiller Phillip J. (Racine County WI), Odor absorbing compositions.
  • Konno Yutaka (Saitama JPX) Kawata Hiroitsu (Saitama JPX) Aruga Masayoshi (Saitama JPX) Sonobe Takashi (Saitama JPX) Mitomi Mitsuo (Tokyo JPX), Patch.
  • Kaiser Carl (Haddon Heights NJ) Pendleton Robert G. (Philadelphia PA), Pharmaceutical compositions and methods involving benzazepine derivatives.
  • Farhadieh Bahram (Libertyville IL) Gokhale Rajeev D. (Vernon Hills IL), Single layer transdermal drug administration system.
  • Miranda Jesus (Miami FL) Sablotsky Steven (Miami FL), Solubility parameter based drug delivery system and method for altering drug saturation concentration.
  • Mitchnick Mark A. ; Gwozdz Garry, Stabilized ascorbic acid, composition, and method of use.
  • Dumler Walter,DEX ; Frankhauser Peter,CHX ; Luther Helmut,DEX, Sunscreen compositions comprising micronized, insoluble organic UV absorbers.
  • Morishita Masataka (Shizuoka JPX) Aikawa Renji (Shizuoka JPX) Katsuragi Shigeo (Shizuoka JPX) Yamamoto Yoshiaki (Shizuoka JPX) Sugimoto Kenichi (Shizuoka JPX), Suppository preparation having excellent absorption property.
  • Godbey Kristin J. (Vadnais Heights MN) Martin Philip G. (White Bear Lake MN), Tramsdermal drug delivery device.
  • Brown Larry R. (Newton MA) Cline John F. (Westfield NJ) Davidson ; deceased James (late of Brookline MA by Betty Davidson ; executrix), Transdermal administration of amines with minimal irritation and high transdermal flux rate.
  • Grasela John C. ; Grasela Joseph E. ; Jubenville Robert M. ; McCloskey Joseph J., Transdermal delivery of medications using a combination of penetration enhancers.
  • Kochinke Frank (San Jose CA) Pfister William R. (Union City CA) Louie Jenny (Fremont CA) Arenson Dan (Escondido CA), Transdermal delivery systems for the modulated administration of drugs.
  • Fawzi Mahdi B. (Flanders NJ) Iyer Uma R. (Mendham NJ) Mahjour Majid (Netcong NJ), Use of commercial lecithin as skin penetration enhancer.
  • Zupan Jacob A. (St. Joseph MO), Use of eucalyptol for enhancing skin permeation of bio-affecting agents.
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