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특허 상세정보

Polymeric tissue sealant

특허상세정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판) A61K-031/74    A61L-024/04    A61L-031/06    C08G-065/332    C08G-065/333    C08G-065/334    C08L-071/02    A61L-024/00    C08G-063/00    A61K-047/34   
출원번호 US-0598786 (2015-01-16)
등록번호 US-9180222 (2015-11-10)
발명자 / 주소
출원인 / 주소
대리인 / 주소
    Pabst Patent Group LLP
인용정보 피인용 횟수 : 0  인용 특허 : 91
초록

Methods for making biomaterials for use as a tissue sealant, kits containing precursors for forming the biomaterials, and the resulting biomaterials are described herein. The biomaterials are formed from a composition comprising at least a first and a second precursor molecule, wherein: i) the first precursor molecule is a poly(ethylene glycol) based polymer having x nucleophilic groups selected from the group consisting of thiol or amino groups, wherein x is greater than or equal to 2ii) the second precursor molecule is of the general formula: A-(C3H6O)...

대표
청구항

1. A kit comprising: i) a poly(ethylene oxide) molecule comprising x nucleophilic groups selected from the group consisting of thiol and amino groups, wherein x is greater than or equal to 2; andii) a molecule of general formula: A-[(C3H6O)n-(C2H4O)m-B]iwherein m and n are integers from 1 to 200;i is greater than 2;A is a branch point; andB is a conjugated unsaturated group. 2. The kit of claim 1, further comprising a basic solution. 3. The kit of claim 2, wherein the basic solution comprises sodium carbonate. 4. The kit of claim 1, further comprising a ...

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