A device containing a temperature-sensitive material comprises a first part containing the material, a second part which engages the first part and allows, or can be disengaged or displaced to allow, the material to be dispensed or utilised, a locking means, and a temperature-sensitive activator for
A device containing a temperature-sensitive material comprises a first part containing the material, a second part which engages the first part and allows, or can be disengaged or displaced to allow, the material to be dispensed or utilised, a locking means, and a temperature-sensitive activator for the locking means that is activated at a predetermined temperature, and thereby irreversibly prevents the material from being dispensed or utilised should it become frozen or exposed to temperatures below a predetermined limit.
대표청구항▼
1. A device containing a freeze-sensitive liquid containing a pharmaceutical or medical product suitable for use in therapy or diagnosis, the device comprising a first part containing the freeze-sensitive liquid, a second part which engages the first part and allows, or can be disengaged or displace
1. A device containing a freeze-sensitive liquid containing a pharmaceutical or medical product suitable for use in therapy or diagnosis, the device comprising a first part containing the freeze-sensitive liquid, a second part which engages the first part and allows, or can be disengaged or displaced to allow, the liquid to be dispensed or utilised, a locking means for irreversibly preventing the freeze-sensitive liquid from being dispensed, and a freeze-sensitive activator for the locking means, wherein the freezing of an aqueous liquid engages the locking means, whereby thawing of the aqueous liquid will not reverse the locking means. 2. The device according to claim 1, which also includes an indicator of the state of the locking means. 3. The device according to claim 1, wherein the first part is a syringe barrel. 4. The device according to claim 3, wherein the freeze-sensitive liquid comprises the aqueous liquid, whereby expansion of the aqueous liquid in the syringe barrel activates the locking means. 5. The device according to claim 4, which includes a means to facilitate mixing of the freeze-sensitive liquid prior to administration. 6. The device according to claim 3, wherein the syringe barrel includes a luer-lock, luer-slip or other type of connector to enable a closure to be attached to an end of the syringe barrel which can be removed to allow a syringe needle to be attached to an end of the first part prior to use. 7. The device according to claim 3, wherein the syringe barrel has an attached needle. 8. The device according to claim 3, which includes a means to prevent re-use of the a syringe integral with the second part. 9. The device according to claim 8, wherein the means to prevent re-use is a needle retraction system. 10. The device according to claim 3, which includes a means to prevent a needle stick injury integral with the second part. 11. The device according to claim 10, wherein the means to prevent a needle stick injury is a needle retraction system. 12. A device containing a freeze-sensitive liquid, the device comprising: a compartment containing the freeze-sensitive liquid;a delivery system integral with the compartment comprising a mechanical structure that disperses the freeze-sensitive liquid;a locking mechanism that disables the delivery system; andan aqueous liquid proximate to the locking mechanism, wherein the locking mechanism is actuated by a change in a physical property of the aqueous liquid. 13. The device of claim 12, wherein the locking mechanism is integral with the delivery system.
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이 특허에 인용된 특허 (15)
Hjorth Richard N. (King of Prussia PA), Adjuvants for viral vaccines.
D'Annunzio, Lindsay L.; D'Annunzio, Anthony J.; D'Annunzio, Courtney L.; Shannon, Russell A; Quiter, John, Device and method for preventing the use of a compromised pharmaceutical that is stored in a vial or similar container.
Spencer Treesa A. (1882 Winnebago El Toro CA 92630), Disposable hypodermic syringe and needle combination having retractable, accident preventing sheath.
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