초록 ▼

A vacuum assist apparatus can comprise a microplate. The microplate can comprise a first surface and an opposing second surface. A plurality of wells can be formed in the first surface of the microplate. Each of the plurality of wells can be sized to receive an assay therein. A support base can comp

A vacuum assist apparatus can comprise a microplate. The microplate can comprise a first surface and an opposing second surface. A plurality of wells can be formed in the first surface of the microplate. Each of the plurality of wells can be sized to receive an assay therein. A support base can comprise a fluid passage. The microplate can be positioned adjacent and in contact with the support base. A pressure device, in fluid communication with the fluid passage, can exert a vacuum within the fluid passage to actively retain the microplate in the contact with the support base.

대표청구항 ▼

1. A sequence detection system, comprising: a liquid handling device comprising a substrate, the substrate further comprising a main body and at least one microfluidic channel within the main body for retaining an assay;a thermal system comprising, at least one sample block, the sample block further

1. A sequence detection system, comprising: a liquid handling device comprising a substrate, the substrate further comprising a main body and at least one microfluidic channel within the main body for retaining an assay;a thermal system comprising, at least one sample block, the sample block further comprising a first surface and a second surface, wherein the first surface comprises at least one channel;a vacuum source fluidly coupled to the at least one channel in the first surface of the sample block capable of evacuating the channel;at least one thermoelectric device coupled to the second surface of the sample block;a control system electrically connected to the at least one thermoelectric device and at least one temperature sensor and configured to regulate a desired thermal output of the sample block;an excitation system comprising at least one optical emission device, optically coupled to the liquid handling device and configured to illuminate the liquid handling device; anda detection system comprising a segmented detector, optically coupled to the liquid handling device and configured to gather emission from the liquid handling device. 2. The sequence detection system of claim 1, wherein the at least one optical emission device comprises at least one light emitting diode (LED). 3. The sequence detection system of claim 1, wherein the segmented detector comprises a CCD. 4. The sequence detection system of claim 1, wherein the detector is configured to gather fluorescence emission from the liquid handling device.