System and method for measuring the pressure of a fluid system within a patient
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61B-005/03
A61B-019/00
출원번호
US-0496871
(2009-07-02)
등록번호
US-9220424
(2015-12-29)
발명자
/ 주소
Wilson, Stephen F.
Dextradeur, Alan J.
출원인 / 주소
DePuy Synthes Products, Inc.
대리인 / 주소
Nutter McClennen & Fish LLP
인용정보
피인용 횟수 :
1인용 특허 :
58
초록▼
A pressure sensing apparatus has a pressure sensor component that includes a pressure sensing port, a pressure sensor for sensing a pressure of a fluid in the pressure sensing port, and a digital processor communicating with the pressure sensor for performing calculations involving fluid pressures s
A pressure sensing apparatus has a pressure sensor component that includes a pressure sensing port, a pressure sensor for sensing a pressure of a fluid in the pressure sensing port, and a digital processor communicating with the pressure sensor for performing calculations involving fluid pressures sensed. The pressure sensing apparatus further includes a first chamber in fluid contact with the pressure sensing port, a second chamber fluidically connectable with a patient's cerebrospinal fluid system, and a membrane located between the first and second chambers so as to transmit fluid pressure from the second chamber to the first chamber.
대표청구항▼
1. A pressure sensor component comprising: a pressure sensing port for containing a fluid for pressure sensing; anda pressure sensor for measuring a pressure of the fluid in the pressure sensing port, wherein the pressure measured is indicative of a patient's cerebrospinal fluid pressure;wherein the
1. A pressure sensor component comprising: a pressure sensing port for containing a fluid for pressure sensing; anda pressure sensor for measuring a pressure of the fluid in the pressure sensing port, wherein the pressure measured is indicative of a patient's cerebrospinal fluid pressure;wherein the pressure sensor component includes a digital processor in electrical communication with the pressure sensor, the pressure sensor component being configured to calculate at least two selected from the group consisting of resting pressure, outflow resistance, and pressure volume index based on the cerebrospinal fluid pressure. 2. The pressure sensor component of claim 1, wherein the pressure sensor component includes a display. 3. The pressure sensor component of claim 2, wherein the pressure sensor component is configured to display a graph of fluid pressures sensed over time. 4. The pressure sensor component of claim 1, wherein the pressure sensor component is configured to calculate at least one selected from the group consisting of resting pressure, outflow resistance, and pressure volume index in multiple iterations with selective calculation of mean results. 5. The pressure sensor component of claim 1, wherein the pressure sensor component is configured to calculate each of a resting pressure, an outflow resistance, and a pressure volume index. 6. The pressure sensor component of claim 1, wherein the pressure sensor component is an integral, hand-held component. 7. The pressure sensor component of claim 6, further comprising a pressure transmission medium in fluid contact with the pressure sensing port. 8. The pressure sensor component of claim 7, wherein the pressure transmission medium is a liquid. 9. The pressure sensor component of claim 8, wherein the liquid is other than cerebrospinal fluid. 10. The pressure sensor component of claim 6, further comprising a catheter connected to the pressure sensing port. 11. The pressure sensor component of claim 10, wherein the catheter includes a membrane that divides the catheter into a first chamber in fluid contact with the pressure sensing port and a second chamber fluidically connectable with a patient's cerebrospinal fluid system, the membrane transmitting fluid pressure from the second chamber to the first. 12. The pressure sensor component of claim 11, wherein the first chamber is filled with a liquid. 13. The pressure sensor component of claim 10, wherein the catheter includes a port for adding a liquid bolus to a patient's cerebrospinal fluid system. 14. The pressure sensor component of claim 13, wherein the port is a three-way stopcock. 15. The pressure sensor component of claim 2, wherein the pressure sensor component includes at least one button for operating the component. 16. The pressure sensor component of claim 15, wherein the processor is configured to calculate at least one selected from the group consisting of outflow resistance and pressure volume index. 17. The pressure sensor component of claim 16, wherein the pressure sensor component is configured to prompt a user through a sequence of measurement steps, the measurement steps including the injection of a bolus into the fluid system being measured. 18. The pressure sensor component of claim 17, wherein the pressure sensor component is configured to prompt a user to infuse the fluid system being measured with a measured volume of fluid. 19. The pressure sensor component of claim 18, wherein the pressure sensor component is configured to prompt a user to wait for a predetermined amount of time. 20. The pressure sensor component of claim 18, wherein the pressure sensor component is configured to prompt a user to wait for a predetermined pressure reading. 21. The pressure sensor component of claim 18, further comprising a catheter connected to the pressure sensing port. 22. The pressure sensor component of claim 21, wherein the catheter includes a port for adding a liquid bolus to a patient's cerebrospinal fluid system. 23. The pressure sensor component of claim 1, wherein the pressure sensor component is configured to calculate the pressure volume index (PVI) as a pressure change resulting from a rapid injection or withdrawal of a bolus fluid from a patient's CSF space. 24. The pressure sensor component of claim 23, wherein the pressure sensor component is further programmed configured to calculate the PVI as: PVI=Vo/Log(Pp/Po)where:Vo is the volume of the bolus;Po is the resting pressure; andPp is the peak pressure resulting from the addition of the bolus. 25. The pressure sensor component of claim 1, wherein the pressure sensor component is programmed configured to calculate the outflow resistance (Ro) as indicative of a return trajectory of a patient's CSF pressure following the addition of a bolus fluid to a patient's CSF space. 26. The pressure sensor component of claim 25, wherein the pressure sensor component is further configured to calculate Ro as: Ro=t2×Po/PVI×Log {(P2/Pp)(Pp−Po)/(P2−Po)}where:t2 is a measured time;Po is the resting pressure;PVI is the pressure volume index;P2 is a measured pressure reading at time t2 after the bolus addition; andPp is the peak pressure resulting from the addition of the bolus.
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