초록 ▼

A system for mixing or reconstituting agents including engageable syringe barrels, one of which having a male engagement region and the other a female engagement region. Each of the male and female engagement regions is provided with a screen. The screens are closely spaced from one another when the

A system for mixing or reconstituting agents including engageable syringe barrels, one of which having a male engagement region and the other a female engagement region. Each of the male and female engagement regions is provided with a screen. The screens are closely spaced from one another when the first and second syringe barrels are engaged with one another. The screens may take the form of a mesh, a plurality of protuberances, or cantilevered wedges having tapering thicknesses.

대표청구항 ▼

1. A method for reconstituting a powdered agent comprising: providing a first syringe barrel including a main chamber defined by a cylindrical barrel wall, an open proximal end, and a male engagement region at a distal end, the male engagement region including a first screen, wherein the first scree

1. A method for reconstituting a powdered agent comprising: providing a first syringe barrel including a main chamber defined by a cylindrical barrel wall, an open proximal end, and a male engagement region at a distal end, the male engagement region including a first screen, wherein the first screen comprises a first plurality of cantilevered wedges, each of the first plurality of cantilevered wedges having a single pointed tip;wherein each of the first plurality of cantilevered wedges has a thickness along a longitudinal axis of the first syringe barrel that tapers, with the thickness of the cantilevered wedge along the longitudinal axis of the first syringe barrel decreasing from a perimeter of the first screen to the pointed tip of the cantilevered wedge;wherein a first screen slot is defined between each pair of the first plurality of cantilevered wedges; andwherein each of the first plurality of cantilevered wedges is configured to bend in a direction of flow of solution across the first screen and each of the first screen slots increases in width during flow of solution across the first screen;providing a second syringe barrel including a main chamber defined by a cylindrical barrel wall, an open proximal end, and a female engagement region at a distal end, the female engagement region including a second screen, wherein the second screen comprises a second plurality of cantilevered wedges, each of the second plurality of cantilevered wedges having a single pointed tip;wherein each of the second plurality of cantilevered wedges has a thickness along a longitudinal axis of the second syringe barrel that tapers, with the thickness of the cantilevered wedge along the longitudinal axis of the second syringe barrel decreasing from a perimeter of the second screen to the pointed tip of the cantilevered wedge;wherein a second screen slot is defined between each pair of the second plurality of cantilevered wedges; andwherein each of the second plurality of cantilevered wedges is configured to bend in a direction of flow of solution across the second screen and each of the second screen slots increases in width during flow of solution across the second screen;depositing the powdered agent into the main chamber of one of the first syringe barrel or the second syringe barrel;inserting a plunger in the open proximal end of the first syringe barrel;inserting a plunger in the open proximal end of the second syringe barrel;drawing a diluent into the main chamber of one of the first syringe barrel or the second syringe barrel;engaging the male engagement region of the first syringe barrel with the female engagement region of the second syringe barrel; andtilting the engaged first and second syringe barrels back and forth to mix the powdered agent and diluent to form a mixture. 2. The method of claim 1, wherein in providing the first syringe barrel, the first syringe barrel includes a neck portion and the male engagement region includes a cylindrical inner wall and a cylindrical outer wall, each of the cylindrical inner and outer walls axially extending in a distal direction from the neck portion and defining a threaded channel therebetween and the first screen extends radially inwardly from the cylindrical inner wall. 3. The method of claim 1, wherein in providing the second syringe barrel, the second syringe barrel includes a neck portion, the female engagement region includes an axially extending cylindrical wall including at least one male thread on an outer surface thereof, and the second screen extends radially inwardly from the axially extending cylindrical wall of the second syringe barrel. 4. The method of claim 1, wherein in providing each of the first syringe barrel and the second syringe barrel, each of the first syringe barrel and second syringe barrel includes a pair of flanges projecting radially outwardly therefrom, and in engaging the male engagement region of the first syringe barrel with the female engagement region of the second syringe barrel, substantially aligning the pair of flanges projecting radially from the first syringe barrel with the pair of flanges projecting radially from the second syringe barrel when the first syringe barrel and the second syringe barrel are fully engaged with one another. 5. The method of claim 1, wherein in tilting the engaged first and second syringe barrels back and forth, expanding the width of the slots between each pair of the first plurality of adjacent cantilevered wedges and expanding the width of the slots between each pair of the second plurality of adjacent cantilevered wedges. 6. The method of claim 1, further comprising, after tilting the engaged first and second syringe barrels back and forth: tilting the engaged first and second syringe barrels so that the mixture is disposed in the second syringe barrel;disengaging the first and second syringe barrels; andattaching an adapter to the female engagement region of the second syringe barrel.