Film-forming composition, and use thereof for treating herpes
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61Q-017/00
A61Q-019/00
A61L-026/00
A61K-009/00
A61K-047/38
A61K-009/70
출원번호
US-0127237
(2012-06-21)
등록번호
US-9226989
(2016-01-05)
우선권정보
FR-11 55493 (2011-06-22)
국제출원번호
PCT/FR2012/051417
(2012-06-21)
§371/§102 date
20131218
(20131218)
국제공개번호
WO2012/175879
(2012-12-27)
발명자
/ 주소
Derain, Nathalie
출원인 / 주소
LABORATOIRES URGO
대리인 / 주소
McAndrews, Held & Malloy Ltd.
인용정보
피인용 횟수 :
0인용 특허 :
6
초록▼
The present invention relates to a topical film-forming composition including, in a pharmaceutically acceptable medium: 5 to 30 wt % of ethyl cellulose; 0.1 to 10 wt % of an auxiliary film-forming agent; 0.1 to 20 wt % of one or more triacids, at least one of which is boric acid; and 60 to 95 wt % o
The present invention relates to a topical film-forming composition including, in a pharmaceutically acceptable medium: 5 to 30 wt % of ethyl cellulose; 0.1 to 10 wt % of an auxiliary film-forming agent; 0.1 to 20 wt % of one or more triacids, at least one of which is boric acid; and 60 to 95 wt % of an organic solvent, the percentages being expressed by weight relative to the total weight of the composition. The invention also relates to the use of such a composition in a method for treating herpes, in particular herpes labialis.
대표청구항▼
1. A topical film-forming composition comprising, in a pharmaceutically acceptable medium: 5% to 30% by weight of ethylcellulose;0.1% to 20% by weight of an auxiliary film-forming agent;0.1% to 5% by weight of one or more triacids, at least one of which is boric acid; and60% to 95% by weight of an o
1. A topical film-forming composition comprising, in a pharmaceutically acceptable medium: 5% to 30% by weight of ethylcellulose;0.1% to 20% by weight of an auxiliary film-forming agent;0.1% to 5% by weight of one or more triacids, at least one of which is boric acid; and60% to 95% by weight of an organic solvent,the percentages being expressed by weight, relative to the total weight of the composition. 2. The composition of claim 1, wherein the ethylcellulose is present in a content ranging from 8% to 20% by weight relative to the total weight of the composition. 3. The composition of claim 2, wherein the ethylcellulose is present in a content ranging from 8% to 15% by weight, relative to the total weight of the composition. 4. The composition of claim 1, wherein the auxiliary film-forming agent is chosen from oxyethylenated derivatives. 5. The composition of claim 4, wherein the oxyethylenated derivative is an oxyethylenated oil. 6. The composition of claim 5, wherein said oxyethylenated oil is vegetable oil. 7. The composition of claim 1, wherein the auxiliary film-forming agent is present in a content ranging from 2% to 12% by weight, relative to the total weight of the composition. 8. The composition as of claim 1, wherein the triacid comprises a mixture of boric acid and citric acid. 9. The composition of claim 8 wherein the mixture of boric acid and citric acid is in a weight ratio of between 1:2 and 2:1. 10. The composition of claim 1, wherein the organic solvent is chosen from alcohols which are liquid at ambient temperature. 11. The composition of claim 10, wherein the alcohol is selected from the group consisting of ethanol, isopropanol, diacetone alcohol, 2 butoxyethanol, cyclohexanol, and mixtures thereof. 12. The composition of claim 11, wherein the alcohol is ethanol. 13. The composition as of claim 1, wherein the organic solvent represents 65% to 85% by weight, relative to the total weight of the composition. 14. The composition of claim 1, wherein said composition further comprises water. 15. The composition of claim 14, wherein said water content is present ranging from 1% to 20% by weight of said composition. 16. The composition of claim 15 wherein said water content is present ranging from 5% to 15% by weight of said composition. 17. The composition of claim 1, wherein it does not contain any additional pharmaceutically active agent for the treatment of herpes. 18. A method for treating herpes, comprising the application of a composition as of claim 1. 19. A method according to claim 18 wherein treating herpes is herpes labialis.
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