Low profile actuator and improved method of caregiver controlled administration of therapeutics
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61M-031/00
A61M-005/142
A61M-005/148
A61M-005/172
출원번호
US-0395627
(2010-09-10)
등록번호
US-9238102
(2016-01-19)
국제출원번호
PCT/US2010/048489
(2010-09-10)
§371/§102 date
20120312
(20120312)
국제공개번호
WO2011/032011
(2011-03-17)
발명자
/ 주소
Banister, Mark
Bloom, William G.
Geronov, Yordan M.
McWilliams, Mark D.
Swenson, David
Van Veen, Mark A.
출원인 / 주소
MEDIPACS, INC.
대리인 / 주소
Hayes Soloway P.C.
인용정보
피인용 횟수 :
0인용 특허 :
162
초록
A polymer actuator, power supply and method of using the activation are described.
대표청구항▼
1. A low profile medication delivery device comprising: a chassis having a first dimension X, a second dimension Y orthogonal to the first dimension X, and a third dimension Z orthogonal to both first dimension X and second dimension Y, wherein the first dimension X and the second dimension X form a
1. A low profile medication delivery device comprising: a chassis having a first dimension X, a second dimension Y orthogonal to the first dimension X, and a third dimension Z orthogonal to both first dimension X and second dimension Y, wherein the first dimension X and the second dimension X form a plane, and wherein the chassis has a first pocket and a second pocket;an actuator assembly overlaying a plurality of collapsible reservoirs disposed within the first pocket; andelectronics disposed within the second pocket and coupled to the actuator assembly, the actuator assembly being configured to separately control expansion and compression of each collapsible reservoir in response to current being passed through the actuator assembly. 2. The low profile medication delivery device of claim 1, wherein the actuator assembly includes an upper electrode, a lower electrode, and a polymeric actuator between the upper electrode and the lower electrode; and wherein the actuator assembly optionally further includes:a sealed flexible outer housing surrounding the upper electrode, the lower electrode, and the polymeric actuator; andan electrolyte solution within the housing and in contact with the polymeric actuator, wherein the polymeric actuator is configured to expand in response to pH changes in the electrolyte solution induced by the current, wherein one of the electrodes preferably is surrounded, at least in part, by a porous separator membrane that facilitates modulation of the pH via charges separation. 3. The low profile medication delivery device of claim 1, further comprising: an upper support adjacent to the upper electrode; anda lower support adjacent the collapsible reservoir, wherein the lower electrode is adjacent to the collapsible reservoir and is configured to function as a piston plate that compresses the collapsible reservoir between the lower support and the lower electrode as the polymeric actuator expands. 4. The low profile medication delivery device of claim 1, further comprising: an upper support adjacent to the upper electrode;a lower support adjacent the plurality of collapsible reservoirs; anda piston plate disposed between the lower electrode and the plurality of collapsible reservoirs. 5. The low profile medication delivery device of claim 1, further comprising: wherein the chassis has a third pocket, and further comprising a second actuator assembly overlaying a second collapsible reservoir disposed within the third pocket. 6. The low profile medication delivery device of claim 1, further comprising: wherein at least two but not all of the collapsible reservoirs are configured to be simultaneously pressurized by the actuator when current is passed through the actuator. 7. The low profile medication delivery device of claim 1, further comprising: wherein the chassis has a length defined along a primary lateral axis, a width defined along a secondary lateral axis, and a depth defined along a depth axis, the chassis having a first pocket and a second pocket arranged and separated along the primary lateral axis to minimize the depth, the length greater than the width, the width greater than the depth;the actuator assembly overlaying the plurality of collapsible reservoirs disposed within the first pocket; andelectrical leads coupling the electronics to the actuator assembly. 8. The low profile medication delivery device of claim 7, further comprising: wherein the actuator assembly expands along the depth axis in response to charge passed from the electronics to the actuator;the actuator assembly includes a polymeric actuator that expands in response to pH changes within the actuator assembly, and the electronics are configured to deliver current to the actuator assembly that modulates the pH; andthe primary lateral axis, the secondary lateral axis, and the depth axis are mutually perpendicular. 9. The low profile medication delivery device of claim 1, further comprising: further comprising:a lower support;an upper support fixedly coupled to the lower support;a collapsible fluid reservoir positioned adjacent to the lower support;an actuator assembly positioned between the collapsible fluid reservoir and the upper support, the actuator assembly including:an upper electrode proximate the upper support; anda polymeric actuator positioned adjacent to the upper electrode; anda piston plate positioned between the polymeric actuator and the collapsible fluid reservoir. 10. The low profile medication delivery device of claim 9, further comprising: wherein the polymeric actuator is configured to change dimensionally in response to pH changes within the actuator assembly;the piston plate is a lower electrode within the actuator assembly;the actuator assembly includes a lower electrode that is proximate to the piston plate; andthe upper electrode has a first area, the piston plate has a second area that is larger than the first area to maximize volumetric efficiency of the low profile medication delivery apparatus. 11. The low profile medication delivery device of claim 10, further comprising: (v) further comprising a housing having mutually orthogonal axes including a major lateral axis having a first dimension, a minor lateral axis having a second dimension, and a depth axis having a third dimension, the housing enclosing two pockets that are arranged along the major lateral axis including a first pocket and a second pocket, the actuator assembly overlaying the plurality of collapsible reservoirs within the first pocket, the depth axis less than either the first dimension or the second dimension, wherein the second pocket optionally contains electronics coupled to the actuator assembly and configured to deliver current to the actuator assembly, the actuator assembly configured to increase a dimension in the depth axis and to compress the plurality of collapsible reservoirs in response to the current. 12. A low profile medication delivery device comprising: a chassis having a first dimension X, a second dimension Y orthogonal to the first dimension X, and a third dimension Z orthogonal to both first dimension X and second dimension Y, wherein the first dimension X and the second dimension Y form a plane, and wherein the chassis has a first pocket and a second pocket;an actuator assembly including a rigid electrode which functions as a rigid platen overlaying a collapsible reservoir disposed within the first pocket; andelectronics disposed within the second pocket and coupled to the actuator assembly, the actuator assembly being configured to control expansion and compression of the collapsible reservoir in response to current being passed through the actuator assembly. 13. The low profile medication delivery device of claim 12, wherein the actuator assembly includes an upper electrode, a lower electrode, and a polymeric actuator between the upper electrode and the lower electrode; and wherein the actuator assembly optionally further includes:a sealed flexible outer housing surrounding the upper electrode, the lower electrode, and the polymeric actuator; andan electrolyte solution within the housing and in contact with the polymeric actuator, wherein the polymeric actuator is configured to expand in response to pH changes in the electrolyte solution induced by the current, wherein one of the electrodes preferably is surrounded, at least in part, by a porous separator membrane that facilitates modulation of the pH via charges separation. 14. The low profile medication delivery device of claim 12, further comprising: an upper support adjacent to the upper electrode; anda lower support adjacent the collapsible reservoir, wherein the lower electrode is adjacent to the collapsible reservoir and is configured to function as a piston plate that compresses the collapsible reservoir between the lower support and the lower electrode as the polymeric actuator expands. 15. The low profile medication delivery device of claim 12, further comprising: an upper support adjacent to the upper electrode;a lower support adjacent the collapsible reservoir; and a piston plate disposed between the lower electrode and the collapsible reservoir. 16. The low profile medication delivery device of claim 12, further comprising: wherein the chassis has a third pocket, and further comprising a second actuator assembly overlaying a second collapsible reservoir disposed within the third pocket. 17. The low profile medication delivery device of claim 12, further comprising: wherein at least two collapsible reservoirs configured to be simultaneously pressurized by the actuator when current is passed through the actuator. 18. The low profile medication delivery device of claim 12, further comprising: wherein the chassis has a length defined along a primary lateral axis, a width defined along a secondary lateral axis, and a depth defined along a depth axis, the chassis having a first pocket and a second pocket arranged and separated along the primary lateral axis to minimize the depth, the length greater than the width, the width greater than the depth;the actuator assembly overlaying collapsible reservoir disposed within the first pocket; andelectrical leads coupling the electronics to the actuator assembly. 19. The low profile medication delivery device of claim 18, further comprising: wherein the actuator assembly expands along the depth axis in response to charge passed from the electronics to the actuator;the actuator assembly includes a polymeric actuator that expands in response to pH changes within the actuator assembly, and the electronics are configured to deliver current to the actuator assembly that modulates the pH; and the primary lateral axis, the secondary lateral axis, and the depth axis are mutually perpendicular. 20. The low profile medication delivery device of claim 12, further comprising: further comprising:a lower support;an upper support fixedly coupled to the lower support;a collapsible fluid reservoir positioned adjacent to the lower support;an actuator assembly positioned between the collapsible fluid reservoir and the upper support, the actuator assembly including:an upper electrode proximate the upper support; anda polymeric actuator positioned adjacent to the upper electrode; anda piston plate positioned between the polymeric actuator and the collapsible fluid reservoir. 21. The low profile medication delivery device of claim 20, further comprising: wherein the polymeric actuator is configured to change dimensionally in response to pH changes within the actuator assembly;the piston plate is a lower electrode within the actuator assembly;the actuator assembly includes a lower electrode that is proximate to the piston plate; andthe upper electrode has a first area, the piston plate has a second area that is larger than the first area to maximize volumetric efficiency of the low profile medication delivery apparatus. 22. The low profile medication delivery device of claim 21, further comprising: (v) further comprising a housing having mutually orthogonal axes including a major lateral axis having a first dimension, a minor lateral axis having a second dimension, and a depth axis having a third dimension, the housing enclosing two pockets that are arranged along the major lateral axis including a first pocket and a second pocket, the actuator assembly overlaying the collapsible reservoir within the first pocket, the depth axis less than either the first dimension or the second dimension, wherein the second pocket optionally contains electronics coupled to the actuator assembly and configured to deliver current to the actuator assembly, the actuator assembly configured to increase a dimension in the depth axis and to compress the collapsible reservoir in response to the current.
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