A container is provided for storing a product, such as a fat containing liquid product, and includes a body defining a chamber for receiving the product; and a container closure including a sealing portion for sealing the product within the chamber. The container closure includes a member forming a
A container is provided for storing a product, such as a fat containing liquid product, and includes a body defining a chamber for receiving the product; and a container closure including a sealing portion for sealing the product within the chamber. The container closure includes a member forming a substantially fluid-tight seal between the container closure and the body; a nipple in fluid communication with the chamber that seals the chamber with respect to the ambient atmosphere during storage of the product in the chamber and that can be opened to dispense product from the chamber therethrough; and a needle penetrable and laser resealable portion that is penetrable by the needle for aseptically filling the chamber with the product, and that is thermally resealable by the application of laser radiation thereto to seal the product within the chamber.
대표청구항▼
1. An apparatus comprising: a housing defining an inlet end, an outlet end, and a sterile zone between the inlet and outlet ends;a conveyor located at least partially within the sterile zone and configured to support and move a container in a conveyor movement direction from the inlet end toward the
1. An apparatus comprising: a housing defining an inlet end, an outlet end, and a sterile zone between the inlet and outlet ends;a conveyor located at least partially within the sterile zone and configured to support and move a container in a conveyor movement direction from the inlet end toward the outlet end through the sterile zone;a fluid sterilant station located within the sterile zone and configured to transmit a a fluid sterilant onto at least a penetrable portion of the container during movement of the container through the sterile zone to thereby sterilize at least the penetrable portion of the container;at least one sterilant removing station located within the sterile zone and downstream of the fluid sterilant station in the conveyor movement direction, and configured to transmit sterile gas onto at least the penetrable portion of the container during movement of the container through the sterile zone to thereby at least substantially remove the fluid sterilant from at least the penetrable portion of the container; anda filling station located within the sterile zone and downstream of the fluid sterilant station in the conveyor movement direction, the filling station including an injection member that is moveable relative to the container and operable to penetrate the penetrable portion of the container, fill the container through the penetrable portion, and withdraw from the container after filling. 2. An apparatus as defined in claim 1, wherein the fluid sterilant is hydrogen peroxide. 3. An apparatus as defined in claim 1, wherein the sterilant removing station comprises a source of sterile gas coupled in fluid communication with the sterile zone for creating an over pressure of sterile gas within the sterile zone, and means for directing a flow of sterile gas substantially in a direction from the outlet end toward the inlet end of the housing to thereby prevent fluid sterilant from flowing onto containers located downstream of the sterilant removing station. 4. An apparatus as defined in claim 3, wherein the means for directing flow is configured to cause air within the sterile zone to flow in a direction opposite the conveyor movement direction. 5. An apparatus as defined in claim 4, wherein the means for directing flow comprises a first vacuum source located adjacent to an inlet end of the sterile zone, and a second vacuum source located adjacent to an outlet end of the sterile zone, wherein the first vacuum source creates a higher vacuum than the second vacuum source, thereby causing air within the sterile zone to flow in a direction opposite the conveyor movement direction. 6. An apparatus as defined in claim 1, wherein the conveyor includes a plurality of pivotally mounted container supports that engage opposing sides of a respective container supported thereon relative to each other, and substantially isolate a sterile portion of the container located above the container supports relative to a portion of the container located below the container supports to thereby prevent contamination on the lower portion of the container from contaminating the sterile upper portion of the container. 7. An apparatus as defined in claim 1, wherein the temperature of the sterile gas is at least 60° C. 8. An apparatus as defined in claim 1, wherein the fluid sterilant station is coupled in fluid communication with a source of fluid sterilant. 9. An apparatus as defined in claim 1, wherein the sterilant removing station is coupled in fluid communication with a source of sterile gas. 10. An apparatus as defined in claim 1, wherein the injection member is configured to introduce substance into and withdraw or vent gas from the container including a container body defining a chamber for receiving a product and the penetrable portion sealing the chamber with respect to the ambient atmosphere forming a sealed, aseptic, empty chamber therein, the injection member is further configured to penetrate through the penetrable portion and into the chamber, and defines a first passageway for introducing a substance into the container and a second passageway for withdrawing or venting displaced gas from the container; and a pump comprising a first head or channel and a second head or channel, wherein the first head or channel is coupled to the first passageway and the second head or channel is coupled to the second passageway, and configured to inject the substance into the container via the first passageway and simultaneously withdraw or vent the displaced gas from the container via the second passageway. 11. An apparatus as defined in claim 10, wherein the injection member comprises a non-coring filling needle that defines a first lumen and a second lumen, wherein the first lumen defines the first passageway and the second lumen defines the second passageway. 12. An apparatus as defined in claim 10, wherein the injection member comprises a first non-coring needle that defines the first passageway and a second non-coring needle that defines the second passageway. 13. An apparatus as defined in claim 12, wherein the second non-coring needle is laterally spaced relative to the first non-coring needle. 14. An apparatus as defined in claim 10, wherein the second passageway is defined by grooves formed in an outer surface of the injection member for said withdrawing or venting the displaced gas from the container. 15. An apparatus as defined in claim 14, wherein the injection member further comprises a cylindrical sleeve surrounding the grooves, adapted to prevent the penetrable portion from filling or blocking the grooves where the injection member passes through the penetrable portion. 16. A method comprising: mounting a container on a conveyor, the container including a container body defining a chamber for receiving a product, a container closure sealing the chamber with respect to the ambient atmosphere forming a sealed, aseptic, empty chamber therein, and a penetrable portion in fluid communication with the chamber that is penetrable therethrough by an injection member;moving the container by or within housing, a housing said housing containing an inlet end, an outlet end, and a sterile zone between the inlet and outlet ends, in a conveyor movement direction from the inlet end toward the outlet end through the sterile zone;transmitting within the sterile zone a fluid sterilant onto at least the penetrable portion and, in turn, sterilizing with the fluid sterilant at least the penetrable portion;transmitting within the sterile zone and downstream of the fluid sterilant station in the conveyor movement direction a sterile gas onto at least the penetrable portion;substantially removing with the sterile gas the fluid sterilant from at least the penetrable portion;inserting an injection member that is in fluid communication with a source of product through the penetrable portion and into fluid communication with the chamber;aseptically introducing product through the injection member and into the chamber; andwithdrawing the injection member from the penetrable portion. 17. A method as defined in claim 16, further comprising moving the filled container outside of the sterile zone after said withdrawing step. 18. A method as defined in claim 16, further comprising directing an overpressure of sterile gas within the sterile zone, and directing at least a portion of the sterile gas in a flow direction generally from an outlet end of the sterile zone toward an inlet end of the sterile zone to, in turn, prevent fluid sterilant from contacting a container during the filling thereof. 19. A method as defined in claim 16, further comprising the step of heating the sterile gas to at least 60° C. prior to transmitting it onto the at least the penetrable portion of the container. 20. A method as defined in claim 16, wherein the removing step includes flowing air within the sterile zone in a direction opposite the conveyor movement direction. 21. A method as defined in claim 20, wherein the flowing step includes creating a first vacuum located adjacent to an inlet end of the sterile zone and creating a second vacuum located adjacent to an outlet end of the sterile zone, wherein the first vacuum is higher than the second vacuum, thereby causing air within the sterile zone to flow in a direction opposite the conveyor movement direction.
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