A patient controls the delivery of therapy through volitional inputs that are detected by a biosignal within the brain. The volitional patient input may be directed towards performing a specific physical or mental activity, such as moving a muscle or performing a mathematical calculation. In one emb
A patient controls the delivery of therapy through volitional inputs that are detected by a biosignal within the brain. The volitional patient input may be directed towards performing a specific physical or mental activity, such as moving a muscle or performing a mathematical calculation. In one embodiment, a biosignal detection module monitors an electroencephalogram (EEG) signal from within the brain of the patient and determines whether the EEG signal includes the biosignal. In one embodiment, the biosignal detection module analyzes one or more frequency components of the EEG signal. In this manner, the patient may adjust therapy delivery by providing a volitional input that is detected by brain signals, wherein the volitional input may not require the interaction with another device, thereby eliminating the need for an external programmer to adjust therapy delivery. Example therapies include electrical stimulation, drug delivery, and delivery of sensory cues.
대표청구항▼
1. A method comprising: receiving an electrical signal sensed from a patient, wherein the electrical signal comprises an electromyogram (EMG) signal;receiving an indication of an input indicative of a patient activity;associating at least one biosignal with the input indicative of the patient activi
1. A method comprising: receiving an electrical signal sensed from a patient, wherein the electrical signal comprises an electromyogram (EMG) signal;receiving an indication of an input indicative of a patient activity;associating at least one biosignal with the input indicative of the patient activity, wherein the at least one biosignal is based on the electrical signal;detecting, from the patient, the at least one biosignal that results from a volitional patient input corresponding to the input indicative of the patient activity; andcontrolling, by a processor and based on the detection of the at least one biosignal, adjustment of a parameter that at least partially defines therapy delivery to the patient. 2. The method of claim 1, further comprising controlling a therapy module to deliver therapy to the patient according to at least the adjusted parameter. 3. The method of claim 1, wherein detecting the at least one biosignal comprises detecting the at least one biosignal from a brain of the patient. 4. The method of claim 3, wherein the electrical signal is a first electrical signal and the EMG signal is a first EMG signal, and wherein the biosignal is extracted from a second electrical signal comprising at least one of an electroencephalogram (EEG) signal, second EMG signal, electrocorticogram (ECoG) signal or a field potential within the brain of the patient. 5. The method of claim 1, wherein detecting the at least one biosignal comprises detecting the at least one biosignal from one or more muscles associated with the patient activity. 6. The method of claim 1, wherein the biosignal comprises at least one of a frequency component of the electrical signal, an amplitude of the electrical signal, or a pattern in an amplitude waveform of the electrical signal. 7. The method of claim 1, wherein controlling the adjustment of the parameter comprises adjusting the parameter of therapy by at least one of increasing or decreasing a therapy parameter value, shifting between stored therapy programs, or modifying a sensory cue. 8. The method of claim 1, further comprising controlling a feedback mechanism to indicate that the biosignal was detected. 9. The method of claim 1, wherein: receiving the indication of the input indicative of the patient activity comprises receiving, by an implantable medical device, the indication of the input indicative of the patient activity; andassociating the at least one biosignal with the input indicative of the patient activity comprises associating, by the implantable medical device, the at least one biosignal with the input indicative of the patient activity. 10. The method of claim 1, wherein: receiving the indication of the input indicative of the patient activity comprises receiving, by an external programmer for an implantable medical device configured to deliver the therapy to the patient, the indication of the input indicative of the patient activity, the input indicative of the patient activity received via a user interface of the external programmer; andassociating the at least one biosignal with the input indicative of the patient activity comprises associating, by the external programmer, the at least one biosignal with the input indicative of the patient activity. 11. The method of claim 1, wherein the electrical signal is a first electrical signal and the at least one biosignal is an at least one first biosignal, and wherein the method further comprises: receiving a second electrical signal sensed from the patient; andassociating at least one second biosignal with the input indicative of the patient activity, wherein: the at least one second biosignal is based on the second electrical signal,detecting the at least one first biosignal that results from the volitional patient input comprises detecting both of the at least one first biosignal and the at least one second biosignal that each result from the volitional patient input corresponding to the input indicative of the patient activity, andcontrolling adjustment of the parameter comprises controlling, based on the detection of both the at least one first biosignal and the at least one second biosignal, adjustment of the parameter that at least partially defines therapy delivery to the patient. 12. A system comprising: a processor configured to: receive an electrical signal sensed from a patient, wherein the electrical signal comprises an electromyogram (EMG) signal,receive an indication of an input indicative of a patient activity, andassociate at least one biosignal with the input indicative of the patient activity,wherein the at least one biosignal is based on the electrical signal;a biosignal detection module configured to detect, from the patient, the at least one biosignal that results from a volitional patient input corresponding to the input indicative of the patient activity; anda therapy module configured to deliver therapy to the patient, wherein the therapy is at least partially defined by a parameter adjusted based on the detection of the at least one biosignal. 13. The system of claim 12, wherein the biosignal detection module is configured to detect the at least one biosignal from a brain of the patient. 14. The system of claim 13, wherein the electrical signal is a first electrical signal and the EMG signal is a first EMG signal, and wherein the biosignal detection module is configured to extract the biosignal from a second electrical signal comprising at least one of an electroencephalogram (EEG) signal, second EMG signal, electrocorticogram (ECoG) signal or a field potential within the brain of the patient. 15. The system of claim 12, wherein the biosignal detection module is configured to detect the at least one biosignal from one or more muscles associated with the patient activity. 16. The system of claim 12, wherein the biosignal comprises at least one of a frequency component of the electrical signal, an amplitude of the electrical signal, or a pattern in an amplitude waveform of the electrical signal. 17. The system of claim 12, further comprising a feedback mechanism separate from the therapy module, wherein the processor is configured to control the feedback mechanism to indicate that the biosignal was detected. 18. The system of claim 12, further comprising an implantable medical device that comprises the processor, and wherein the processor is configured to control, based on the detection of the at least one biosignal, adjustment of the parameter that at least partially defines therapy delivered by the therapy module. 19. The system of claim 12, wherein the processor is a first processor, and wherein the system further comprises: an external programmer that comprises the first processor; andan implantable medical device comprising a second processor configured to control, based on the detection of the at least one biosignal, adjustment of the parameter that at least partially defines therapy delivered by the therapy module. 20. A non-transitory computer-readable storage medium comprising one or more instructions that, when executed, cause one or more processors to: receive an electrical signal sensed from a patient, wherein the electrical signal comprises an electromyogram (EMG) signal;receive an indication of an input indicative of a patient activity;associate at least one biosignal with the input indicative of the patient activity, wherein the at least one biosignal is based on the electrical signal;detect, from the patient, the at least one biosignal that results from a volitional patient input corresponding to the input indicative of the patient activity; andcontrol, based on the detection of the at least one biosignal, adjustment of a parameter that at least partially defines therapy delivered to the patient. 21. The non-transitory computer-readable storage medium of claim 20, further comprising instructions that cause the one or more processors to control a feedback mechanism to indicate that the biosignal was detected. 22. A system comprising: means for receiving an electrical signal sensed from a patient, wherein the electrical signal comprises an electromyogram (EMG) signal;means for receiving an indication of an input indicative of a patient activity;means for associating at least one biosignal with the input indicative of the patient activity, wherein the at least one biosignal is based on the electrical signal;means for detecting, from the patient, the at least one biosignal that results from a volitional patient input corresponding to the input indicative of the patient activity; andmeans for controlling, based on the detection of the at least one biosignal, adjustment of a parameter that at least partially defines therapy delivery to the patient. 23. The system of claim 22, wherein the means for detecting the at least one biosignal comprises means for detecting the at least one biosignal from a brain of the patient. 24. The system of claim 22, wherein the means for detecting the at least one biosignal comprises means for detecting the at least one biosignal from one or more muscles associated with the patent activity. 25. A method comprising: receiving, by an external programmer, an electrical signal sensed from a patient, the external programmer including a user interface and a telemetry module;receiving, by the external programmer and via the user interface, an input indicative of patient activity;associating, by the external programmer, at least one biosignal with the input indicative of the patient activity, wherein the at least one biosignal is based on the electrical signal;detecting, from the patient, the at least one biosignal that results from a volitional patient input corresponding to the input indicative of the patient activity; andcontrolling, by a processor and based on the detection of the at least one biosignal, adjustment of a parameter that at least partially defines therapy delivery to the patient. 26. A system comprising: an external programmer comprising a user interface and a telemetry module, the external programmer configured to: receive an electrical signal sensed from a patient,receive, via the user interface, an input indicative of a patient activity, andassociate at least one biosignal with the input indicative of the patient activity,wherein the at least one biosignal is based on the electrical signal;a biosignal detection module configured to detect, from the patient, the at least one biosignal that results from a volitional patient input corresponding to the input indicative of the patient activity; anda therapy module configured to deliver therapy to the patient, wherein the therapy is at least partially defined by a parameter adjusted based on the detection of the at least one biosignal.
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이 특허에 인용된 특허 (110)
Meyerson Scott C. (Mounds View MN) Linder William J. (Golden Valley MN) Maile Keith R. (New Brighton MN), Acceleration-sensitive cardiac pacemaker and method of operation.
Esteller,Rosana; Echauz,Javier Ram?n; Litt,Brian; Vachtsevanos,George John, Adaptive method and apparatus for forecasting and controlling neurological disturbances under a multi-level control.
Goedeke Steven D. ; Haubrich Gregory J. ; Keimel John G. ; Thompson David L., Adaptive, performance-optimizing communication system for communicating with an implanted medical device.
Yoav Kimchi IL; David Prutchi ; Itzhak Shemer IL, Apparatus and method for determining a mechanical property of an organ or body cavity by impedance determination.
Thakor,Nitish V; Bezerianos,Anastasios; Al Hatib,Feras; Al Nashash,Hasan; Paul,Joseph; Sherman,David; Tong,Shanbao; Venkatesha,Santosh, Apparatus and methods for brain rhythm analysis.
Adkins Robert A. ; O'Donovan Cormac A. ; Terry ; Jr. Reese S., Automatic activation of a neurostimulator device using a detection algorithm based on cardiac activity.
Olsen Dale E. (Columbia MD) Lesser Ronald P. (Baltimore MD) Harris John C. (Gaithersburg MD) Webber W. Robert S. (Howard County MD) Cristion John A. (Columbia MD), Automatic detection of seizures using electroencephalographic signals.
Salo Rodney W. (Fridley MN) Spinelli Julio C. (Shoreview MN) Tockman Bruce A. (Minneapolis MN), Cardiac stimulating apparatus and method for heart failure therapy.
Nordeng Arnold E. (4311 S. 4th Ave. Everett WA 98203), Chopper stabilized amplifier having an additional differential amplifier stage for improved noise reduction.
Olive Arthur L. (Stacy MN) Pederson Brian D. (St. Paul MN) Salo Rodney W. (Fridley MN), Closed loop control of cardiac stimulator utilizing rate of change of impedance.
Settle Wayne L. (1311 33rd Ave. San Francisco CA 94122) Funston Lowell G. (1309 33rd Ave. San Francisco CA 94122), Electroencephalographic activated control system.
Dal Molin, Renzo, Measurement of intracardiac impedance in a multisite-type, active implantable medical device, in particular a pacemaker, defibrillator and/or cardiovertor.
Dal Molin, Renzo, Measuring a trans-septum bio-impedance in an active implantable medical device, in a particular pacemaker, defibrillator and/or cadiovertor and/or multisite device.
Litt, Brian; Vachtsevanos, George; Echauz, Javier; Esteller, Rosana, Method and apparatus for predicting the onset of seizures based on features derived from signals indicative of brain activity.
Huvelle, Etienne; Sanchez, Francisca Cuesta, Method and apparatuses for monitoring hemodynamic activities using an intracardiac impedance-derived parameter.
Litt Richard O. (Rapid City IL) Schilb Christopher J. (Bettendorf IA) Gorge Brian C. (Moline IL), Method and device for aligning a tool held by a robot.
Andres M. Lozano CA; Mark T. Rise, Method of treating movement disorders by electrical stimulation and/or drug infusion of the pendunulopontine nucleus.
Hartley Jesse W. ; Cohen Marc H. ; Stessman Nicholas J. ; Reedstrom Scott A. ; Check Steven D. ; Nelson James P., Rate adaptive cardiac rhythm management device using transthoracic impedance.
Pless, Benjamin D.; Archer, Stephen T.; Baysinger, Craig M.; Gibb, Barbara; Gurunathan, Suresh K.; Kirkpatrick, Bruce; Tcheng, Thomas K., Seizure sensing and detection using an implantable device.
Goetz, Steven M.; Houchins, Andrew H.; Keacher, Jeffrey T.; King, Gary W.; Heruth, Kenneth T.; Testerman, Roy L.; Lee, Michael T.; Torgerson, Nathan A.; Nolan, Joseph J., Shifting between electrode combinations in electrical stimulation device.
Vonk B. F. M. (Wehl NLX) Van Someren Eugenio Johannes W. (Amsterdam NLX), System an method for detecting tremors such as those which result from parkinson\s disease.
Bornzin, Gene A.; Florio, Joseph J.; Sloman, Laurence S., System and method of identifying fusion for dual-chamber automatic capture stimulation device.
Teller, Eric; Stivoric, John M.; Kasabach, Christopher D.; Pacione, Christopher D.; Moss, John L.; Liden, Craig B.; McCormack, Margaret A., System for monitoring health, wellness and fitness.
Dorfmeister Josef ; Frei Mark ; Lerner David ; Osorio Ivan ; Ralston John, System for the prediction, rapid detection, warning, prevention, or control of changes in activity states in the brain o.
Molnar, Gregory F.; Gill, Steven S.; Miesel, Keith A.; Lent, Mark S.; Denison, Timothy J.; Panken, Eric J.; Wahlstrand, Carl D.; Werder, Jonathan C., Therapy control based on a patient movement state.
Wernicke Joachim F. (League City TX) Terry ; Jr. Reese S. (Houston TX) Zabara Jacob (Philadelphia PA), Treatment of neuropsychiatric disorders by nerve stimulation.
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