The present application relates to novel antimicrobial compositions and methods of using said antimicrobial compositions for inhibiting and treating microbial growth, microbial infections, inflammatory diseases, viral diseases, cardiovascular diseases, diabetes and/or conditions that may be regulate
The present application relates to novel antimicrobial compositions and methods of using said antimicrobial compositions for inhibiting and treating microbial growth, microbial infections, inflammatory diseases, viral diseases, cardiovascular diseases, diabetes and/or conditions that may be regulated or associated with microbial infections, such as cancer.
대표청구항▼
1. A method of treating, inhibiting or reducing a condition or disease, comprising administering to a subject a therapeutically effective amount of an antimicrobial solution comprising: water;from about 20% to about 60% by volume of ethanol;from about 0.5% to about 7.5% by volume of a peroxide or pe
1. A method of treating, inhibiting or reducing a condition or disease, comprising administering to a subject a therapeutically effective amount of an antimicrobial solution comprising: water;from about 20% to about 60% by volume of ethanol;from about 0.5% to about 7.5% by volume of a peroxide or peroxide-generating agent; andfrom about 5 mg/mL to about 40 mg/mL of a chelating agent wherein the chelating agent includes ethylenediamine tetraacetic acid (EDTA), acids of EDTA, salts of EDTA, or any combination thereof. 2. The method of claim 1, wherein the condition or disease is a bacterial condition or disease, a viral condition or disease, an inflammatory condition or disease, or immune response condition or disease. 3. The method of claim 1, wherein the solution is administered by topical application, intravenous injection, intraperitoneal injection or implantation, intramuscular injection or implantation, intralesional injection, subcutaneous injection or implantation, intradermal injection, suppositories, pessaries, enteric application, or nasal route. 4. The method of claim 1, wherein the solution is administered to a site selected from the group consisting of a wound site, a catheter site, a surgical site, an injection site, a catheter, a catheter lumen, a thermal burn site, a chemical burn site, a radiation burn site, a skin lesion, oral sites, bony sites, anal sites, vaginal sites, cervical sites, vulvar sites, penile sites, ulcerated skin sites, acne sites, actinic keratosis sites, inflamed sites, irritated sites, gastric sites, gastrointestinal sites, esophageal sites, esophagogastrointestinal sites, intestinal sites, cardiac sites, vascular sites, nasal sites, nasopharyngeal sites, and aural sites. 5. The method according to claim 1, wherein the low molecular weight alcohol is present at a concentration of about 50% by volume. 6. The method of claim 1, wherein the peroxide or peroxide-generating agent is present at a concentration of about 1.5% by volume. 7. The method according to claim 1, wherein the chelating agent is present at a concentration of about 10 mg/ml. 8. The method according to claim 1, wherein the peroxide or peroxide-generating agent comprises hydrogen peroxide. 9. The method according to claim 1, further comprising a viscosity increasing agent. 10. The method according to claim 9, wherein said viscosity increasing agent is carboxymethyl cellulose (CMC), hydroxypropyl methylcellulose (HPMC), methyl cellulose, methyl hydroxyethyl cellulose (MHEC), hydroxyethyl cellulose, sodium hydroxyalkyl celluloses, or admixtures thereof. 11. A method of treating, inhibiting or reducing a condition or disease, comprising administering to a subject a therapeutically effective amount of an antimicrobial solution consisting essentially of: water;from about 20% to about 60% by volume of ethanol;from about 0.5% to about 7.5% by volume of a peroxide or peroxide-generating agent; andfrom about 5 mg/mL to about 40 mg/mL of a chelating agent wherein the chelating agent includes ethylenediamine tetraacetic acid (EDTA), acids of EDTA, salts of EDTA, or any combination thereof. 12. The method according to claim 11, wherein the peroxide or peroxide-generating agent comprises hydrogen peroxide.
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