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Kafe 바로가기국가/구분 | United States(US) Patent 등록 |
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국제특허분류(IPC7판) |
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출원번호 | US-0825406 (2007-07-05) |
등록번호 | US-9265725 (2016-02-23) |
우선권정보 | IL-152486 (2002-10-25) |
발명자 / 주소 |
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출원인 / 주소 |
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대리인 / 주소 |
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인용정보 | 피인용 횟수 : 18 인용 특허 : 527 |
The present invention teaches a foamable pharmaceutical carrier comprising a benefit agent, selected from the group consisting of a dicarboxylic acid and a dicarboxylic acid ester; a stabilizer selected from the group consisting of at least one surface-active agent; at least one polymeric agent and
The present invention teaches a foamable pharmaceutical carrier comprising a benefit agent, selected from the group consisting of a dicarboxylic acid and a dicarboxylic acid ester; a stabilizer selected from the group consisting of at least one surface-active agent; at least one polymeric agent and mixtures thereof; a solvent selected from the group consisting of water, a hydrophilic solvent, a hydrophobic solvent, a potent solvent, a polar solvent, a silicone, an emollient, and mixtures thereof, wherein the benefit agent, stabilizer and solvent are selected to provide a composition that is substantially resistant to aging and to phase separation and or can substantially stabilize other active ingredients. The invention further relates to a foamable composition further containing a liquefied hydrocarbon gas propellant.
1. A foamable composition comprising a formable carrier and a propellant, the foamable carrier comprising: a) about 15% by weight of an azelaic acid;b) about 11% by weight of medium-chain triglycerides;c) about 11% by weight of propylene glycol;d) about 5% by weight of dimethyl isosorbide;e) about 3
1. A foamable composition comprising a formable carrier and a propellant, the foamable carrier comprising: a) about 15% by weight of an azelaic acid;b) about 11% by weight of medium-chain triglycerides;c) about 11% by weight of propylene glycol;d) about 5% by weight of dimethyl isosorbide;e) about 3% by weight of PEG-40 stearate;f) about 1% by weight of a cetostearyl alcohol;g) about 1% by weight of polysorbate 80;h) about 0.5% by weight of a monoglyceride, a diglyceride, or a combination;i) about 0.3% by weight of a xanthan gum;j) about 0.1% by weight of methylcellulose;k) about 0.1% by weight of a benzoic acid;l) water;m) sodium hydroxide; andwherein the pH of said foamable carrier is about 4.5-5.3; andwherein the propellant is at a concentration of about 3% to about 25% by weight of the total composition. 2. The foamable composition of claim 1, wherein the medium-chain triglycerides are caprylic/capric triglycerides. 3. The foamable composition of claim 1, wherein the monoglyceride is glyceryl stearate. 4. The foamable composition of claim 1, wherein the medium-chain triglycerides are caprylic/capric triglycerides and the monoglyceride is glyceryl stearate. 5. A foamable carrier comprising: a) about 15% by weight of an azelaic acid;b) about 11% by weight of medium-chain triglycerides;c) about 11% by weight of propylene glycol;d) about 5% by weight of dimethyl isosorbide;c) about 3% by weight of PEG-40 stearate;f) about 1% by weight of a cetostearyl alcohol;g) about 1% by weight of polysorbate 80;h) about 0.5% by weight of a monoglyceride, a diglyceride, or a combination thereof;i) about 0.3% by weight of a xanthan gum;j) about 0.1% by weight of methylcellulose;k) about 0.1% by weight of a benzoic acid;l) water;m) sodium hydroxide; andwherein the pH of said foamable carrier is about 4.5-5.3. 6. The foamable carrier of claim 5, wherein the medium-chain triglycerides are caprylic/capric triglycerides. 7. The foamable carrier of claim 5, wherein the monoglyceride is glyceryl stearate. 8. The foamable carrier of claim 5, wherein the medium-chain triglycerides are caprylic/capric triglycerides and the monoglyceride is glyceryl stearate.
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