Protein stabilized antimicrobial composition formed by melt processing
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A01N-025/02
A01N-025/10
A01N-025/12
A01N-025/28
A01N-025/34
A01N-043/90
A01N-065/00
B29B-007/42
B29C-047/00
B29C-047/02
B29C-047/60
B29C-047/92
A01N-031/08
출원번호
US-0899615
(2013-05-22)
등록번호
US-9271487
(2016-03-01)
발명자
/ 주소
Topolkaraev, Vasily A.
Scholl, Neil T.
Lee, Jaehong
Ambrose, Dianna L.
Kim, YoungSook
출원인 / 주소
Kimberly-Clark Worldwide, Inc.
대리인 / 주소
Dority & Manning, P.A.
인용정보
피인용 횟수 :
0인용 특허 :
65
초록▼
A method for forming an antimicrobial composition that includes mixing an antimicrobially active botanical oil (e.g., thymol, carvacrol, etc.) and protein within a melt blending device (e.g., extruder) is provided. Despite the problems normally associated with melt processing proteins, the present i
A method for forming an antimicrobial composition that includes mixing an antimicrobially active botanical oil (e.g., thymol, carvacrol, etc.) and protein within a melt blending device (e.g., extruder) is provided. Despite the problems normally associated with melt processing proteins, the present inventors have discovered that the processing conditions and components may be selectively controlled to allow for the formation of a stable, melt-processed composition that is able to exhibit good mechanical properties. For example, the extrusion temperature(s) and shear rate employed during melt blending are relatively low to help limit polypeptide dissociation, thereby minimizing the impact of aggregation and embrittlement. While the use of such low temperature/shear conditions often tend to reduce mixing efficiency, the present inventors have discovered that a carrier fluid may be employed to enhance the ability of the botanical oil to flow into the internal structure of the protein where it can be retained in a stable manner. The composition is also typically anhydrous and generally free of solvents. In this manner, the protein will not generally disperse before use and prematurely release the botanical oil.
대표청구항▼
1. A melt-processed antimicrobial composition comprising at least one monoterpene phenol in an amount of from about 0.1 wt. % to about 30 wt. %, at least one melt-processible plant protein in an amount of from about 30 wt. % to about 95 wt. %, and at least one carrier fluid in amount of from about 1
1. A melt-processed antimicrobial composition comprising at least one monoterpene phenol in an amount of from about 0.1 wt. % to about 30 wt. %, at least one melt-processible plant protein in an amount of from about 30 wt. % to about 95 wt. %, and at least one carrier fluid in amount of from about 1 wt. % to about 50 wt. %. 2. The composition of claim 1, wherein the monoterpene phenol is thymol, carvacrol, or a mixture thereof. 3. The composition of claim 1, wherein the plant protein is wheat gluten. 4. The composition of claim 1, wherein the carrier fluid is a polyhydric alcohol. 5. The composition of claim 4, wherein the polyhydric alcohol is glycerol. 6. The composition of claim 1, wherein the carrier fluid is an aliphatic carboxylic acid. 7. The composition of claim 1, wherein monoterpene phenols constitute from about 0.5 wt. % to about 20 wt. % of the composition, melt-processible plant proteins constitute from about 40 wt. % to about 90 wt. % of the composition, and carrier fluids constitute from about 5 wt. % to about 30 wt. % of the composition. 8. The composition of claim 1, wherein the composition is general free of solvents. 9. The composition of claim 1, wherein the composition is in the form of particles. 10. The composition of claim 9, wherein the particles have an average size of from about 100 to about 600 micrometers. 11. A wipe comprising the melt-processed antimicrobial composition of claim 1, wherein the wipe includes a fibrous material. 12. The wipe of claim 11, wherein the fibrous material contains absorbent fibers. 13. The wipe of claim 12, wherein the fibrous material is a composite of absorbent fibers and synthetic thermoplastic fibers. 14. A method for removing bacteria from a surface, the method comprising contacting the surface with a wipe that comprises a fibrous material that contains a melt-processed antimicrobial composition comprising at least one monoterpene phenol in an amount of from about 0.1 wt. % to about 30 wt. %, at least one melt-processible plant protein in an amount of from about 30 wt. % to about 95 wt. %, and at least one carrier fluid in amount of from about 1 wt. % to about 50 wt. %. 15. The method of claim 14, wherein prior to contacting the surface with the wipe, an aqueous solution is applied to the composition to release the monoterpene phenol. 16. The method of claim 15, wherein the concentration of the monoterpene phenol released in the aqueous solution is greater than about 0.1 wt. %. 17. The method of claim 15, wherein the concentration of the monoterpene phenol released in the aqueous solution is from about 1 wt. % to about 10 wt. %. 18. The method of claim 15, wherein the aqueous solution contains an acid. 19. The method of claim 14, wherein the composition is in the form of particles. 20. The method of claim 19, wherein the particles have an average size of from about 100 to about 600 micrometers.
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