Radiosurgery systems are described that are configured to deliver a therapeutic dose of radiation to a target structure in a patient. In some embodiments, inflammatory ocular disorders are treated, and in some embodiments, other disorders or tissues of a body are treated with the dose of radiation.
Radiosurgery systems are described that are configured to deliver a therapeutic dose of radiation to a target structure in a patient. In some embodiments, inflammatory ocular disorders are treated, and in some embodiments, other disorders or tissues of a body are treated with the dose of radiation. In some embodiments, target tissues are placed in a global coordinate system based on ocular imaging. In some embodiments, a fiducial marker is used to identify the location of the target tissues.
대표청구항▼
1. A method, of applying x-ray radiation to target tissue, comprising: obtaining imaging data indicative of a target tissue;identifying, based on the imaging data, a location of the target tissue;repeatedly mapping the location of the target tissue in a coordinate system, thereby producing mapped lo
1. A method, of applying x-ray radiation to target tissue, comprising: obtaining imaging data indicative of a target tissue;identifying, based on the imaging data, a location of the target tissue;repeatedly mapping the location of the target tissue in a coordinate system, thereby producing mapped locations of the target tissue in the coordinate system;positioning, based on the mapped locations of the target tissue in the coordinate system, an x-ray collimator that directs an x-ray beam to the target tissue; andemitting the x-ray beam from the collimator to the target tissue, wherein the x-ray beam has a dose distribution at a beam spot in a plane at the target tissue, such that a dose of the x-ray beam at a region within the plane and outside the beam spot is less than 20% of a dose at a centroid of the beam spot. 2. The method of claim 1, further comprising making an incision in tissue overlying the target tissue, prior to emitting the x-ray beam toward the target tissue. 3. The method of claim 1, wherein positioning the x-ray collimator further comprises placing a probe at or adjacent the target tissue. 4. The method of claim 1, wherein the target tissue is located in the vasculature of a patient. 5. The method of claim 1, wherein the target tissue comprises peripheral vasculature. 6. The method of claim 1, wherein the target tissue is located in the heart of a patient. 7. The method of claim 1, wherein the target tissue is located in the gastrointestinal tract of a patient. 8. The method of claim 1, wherein the target tissue comprises the colon or rectum of a patient. 9. The method of claim 1, wherein a tumor comprises the target tissue. 10. The method of claim 1, wherein the target tissue is located in a breast of a patient. 11. The method of claim 1, wherein the target tissue comprises musculoskeletal tissue. 12. The method of claim 1, wherein the target tissue comprises at least one of the liver and the spleen of a patient. 13. The method of claim 1, wherein the beam spot has a cross-sectional dimension smaller than 1 mm. 14. The method of claim 1, wherein the target tissue the beam spot has a diameter of between 1 mm and 5 mm. 15. The method of claim 1, wherein the x-ray beam comprises alternating regions of higher intensity and lower intensity. 16. The method of claim 1, further comprising positioning the target tissue in or on a holding module, wherein the holding module holds the target tissue substantially stationary while the location of the target tissue is mapped in the coordinate system.
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이 특허에 인용된 특허 (183)
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