Metallic-nanofinger device for chemical sensing
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
G01N-021/65
G01N-021/64
출원번호
US-0879245
(2010-10-20)
등록번호
US-9274058
(2016-03-01)
국제출원번호
PCT/US2010/053304
(2010-10-20)
§371/§102 date
20130412
(20130412)
국제공개번호
WO2012/054024
(2012-04-26)
발명자
/ 주소
Li, Zhiyong
Williams, R. Stanley
출원인 / 주소
Hewlett-Packard Development Company, L.P.
대리인 / 주소
HP Inc. Patent Department
인용정보
피인용 횟수 :
0인용 특허 :
59
초록▼
A metallic-nanofinger device for chemical sensing. The device includes a substrate, and a plurality of nanofingers. A nanofinger includes a flexible column, and a metallic cap coupled to an apex of the flexible column. At least the nanofinger and a second nanofinger are to self-arrange into a close-
A metallic-nanofinger device for chemical sensing. The device includes a substrate, and a plurality of nanofingers. A nanofinger includes a flexible column, and a metallic cap coupled to an apex of the flexible column. At least the nanofinger and a second nanofinger are to self-arrange into a close-packed configuration with at least one analyte molecule disposed between at least the metallic cap and a second metallic cap of respective nanofinger and second nanofinger. A morphology of the metallic cap is to generate a shifted plasmonic-resonance peak associated with amplified luminescence from the analyte molecule. A coating encapsulating the metallic cap to respond upon exposure to a liquid, and a chemical-sensing chip including the metallic-nanofinger device are also provided.
대표청구항▼
1. A metallic-nanofinger device for chemical sensing, said device comprising: a substrate; anda plurality of nanofingers coupled with said substrate, a nanofinger of said plurality of nanofingers comprising:a flexible column;a metallic cap coupled to an apex of said flexible column; anda coating enc
1. A metallic-nanofinger device for chemical sensing, said device comprising: a substrate; anda plurality of nanofingers coupled with said substrate, a nanofinger of said plurality of nanofingers comprising:a flexible column;a metallic cap coupled to an apex of said flexible column; anda coating encapsulating said metallic cap,wherein at least said nanofinger and a second nanofinger of said plurality of nanofingers are to self-arrange into a close-packed configuration with at least one analyte molecule disposed between at least said metallic cap and a second metallic cap of respective nanofinger and second nanofinger, wherein a morphology of said metallic cap is to generate a shifted plasmonic-resonance peak associated with amplified luminescence from said analyte molecule, and wherein said coating is to develop a response upon exposure to a liquid. 2. The metallic nanofinger device of claim 1, wherein said plasmonic-resonance peak associated with luminescence from said analyte molecule is shifted towards longer wavelengths. 3. The metallic nanofinger device of claim 1, wherein said plasmonic-resonance peak associated with luminescence from said analyte molecule is shifted towards shorter wavelengths. 4. The metallic-nanofinger device of claim 1, wherein said morphology of said metallic cap as measured by a roughness average of a surface roughness of said metallic cap is such that said roughness average is less than about 5 nanometers (nm). 5. The metallic-nanofinger device of claim 1, wherein said morphology of said metallic cap as measured by a shape parameter of said metallic cap is such that said shape parameter varies from metallic cap to metallic cap of respective metallic nanofingers by no more than between plus 10 nm to minus 10 nm from an average value of said shape parameter. 6. The metallic-nanofinger device of claim 5, wherein said morphology of said metallic cap is substantially spherical, and said shape parameter comprises an average radius of said metallic cap. 7. The metallic-nanofinger device of claim 5, wherein said morphology of said metallic cap is truncated substantially spherical, and said shape parameter comprises an average radius of said metallic cap. 8. A metallic-nanofinger device for chemical sensing, said device comprising: a substrate; anda plurality of nanofingers coupled with said substrate, a nanofinger of said plurality of nanofingers comprising:a flexible column;a metallic cap coupled to an apex of said flexible column; anda coating encapsulating said metallic cap,wherein at least said nanofinger and a second nanofinger of said plurality of nanofingers are to self-arrange into a close-packed configuration with at least one analyte molecule disposed between at least said metallic cap and a second metallic cap of respective nanofinger and second nanofinger, andwherein said coating is to develop a response upon exposure to a liquid. 9. The metallic-nanofinger device of claim 8, wherein said liquid comprises a solute; said solute comprises said analyte molecule; and, said coating has an affinity to react with said analyte molecule. 10. The metallic-nanofinger device of claim 8, wherein said coating comprises properties enabling said coating to dissolve via interacting with a solvent of said liquid. 11. The metallic-nanofinger device of claim 10, wherein said liquid further comprises a solute; said solute comprises said analyte molecule; said coating has an affinity to react with said analyte molecule; and, wherein said analyte molecule is left bound to said metallic cap. 12. The metallic-nanofinger device of claim 8, wherein said coating comprises properties such that said coating does not dissolve via interaction with said liquid. 13. The metallic-nanofinger device of claim 12, wherein said liquid further comprises a solute; said solute comprises said analyte molecule; said coating has an affinity to react with said analyte molecule; and, wherein said analyte molecule is left bound to said coating encapsulating said metallic cap. 14. The metallic-nanofinger device of claim 8, wherein said coating comprises a substance selected from tile group consisting of polymethylmethacrylate, a compound soluble in a solvent, a compound insoluble in a solvent, at least one antibody, at least one antigen, at least one deoxyribonucleic acid segment, at least one ribonucleic acid segment, at least one protein, at least one protein segment, substances to develop a response upon exposure to said liquid, and substances to develop a response upon exposure to an analyte molecule in said liquid. 15. A chemical-sensing chip, comprising: a metallic-nanofinger device for chemical sensing, said device comprising:a substrate; andan array of patches, a patch of said array comprising: a plurality of nanofingers coupled with said substrate, a nanofinger of said plurality of nanofingers comprising: a flexible column; anda metallic cap coupled to an apex of said flexible column; anda coating encapsulating said metallic cap;wherein at least said nanofinger and a second nanofinger of said plurality of nanofingers are to self-arrange into a close-packed configuration with at least one analyte molecule disposed between at least said metallic cap and a second metallic cap of respective nanofinger and second nanofinger; andwherein said coating of said metallic cap in said patch is functionalized with a certain probe molecule to develop a specific response upon exposure to certain targets in a liquid comprising said targets in a complex analyte solution.
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